How Hypopituitarism is Treated | Learn More About …
Posted: December 11, 2019 at 4:47 am
Hormone deficiency is treated by replacing the deficient hormones. The goals of treatment are to improve symptoms (see Table 2) and to replace the deficient hormone or hormones at a level that is as close to physiologically correct (mother nature) as possible. However, one rule of hormone replacement is that no one dose will suit every patient. Thus, when hormone replacement therapy is prescribed, the patient will need to be seen regularly after starting treatment to assess the effect. It often takes time and repeated dose changes to find the optimal dose for each patient. Typically, once the optimal dose is determined, the dose remains adequate for long-term treatment unless other medications are added or the patients condition changes in a way that alters the blood levels (e.g., introduction of GH therapy may require an increase in cortisol replacement, whereas pregnancy may require an increase in the dose of thyroid hormone).
Cortisol: On average, cortisol replacement therapy consists of giving approximately 15 mg of cortisol daily in divided doses. Approximately 2/3 of the dose is given in the morning and 1/3 in the late afternoon or evening. Excess cortisol can cause side effects (see the section on risks below), so it is best to use cortisol replacement in doses that are adequate but not too high.
Some endocrinologists prescribe prednisone instead of cortisol, and the dose of prednisone can be given once or twice a day. Patients with cortisol deficiency must always remember that during periods of stress their bodies may not be able to produce the increased level of cortisol needed. Therefore, patients should always carry a medical or steroid alert card or wear a medical alert bracelet or necklace to inform physicians that they are taking chronic steroid therapy. If patients have multiple pituitary hormone deficiencies, cortisol should always be the first hormone replaced as medications like thyroid hormone or GH can increase the bodys need for cortisol.
Thyroid hormone:Levothyroxine given daily is the therapy for thyroid hormone deficiency.
Sex-related hormones:Women: Premenopausal women who have no menstrual cycles as a result of pituitary disease (secondary hypogonadism) should receive replacement therapy with estrogen and progesterone. Estrogen can be given orally, by patch or by gel. Progesterone equivalent is only required in woman who have an intact uterus. Women who have undergone a hysterectomy can be treated with estrogen alone.
Men: In testosterone-deficient men, testosterone is given by patch, gel or injection either daily (patch or gel) or every 2-4 weeks by intramuscular injection.
GH therapy:GH prescribing practices vary depending upon local customs, national guidelines and insurance coverage. It is important to do tests to prove that patients are indeed GH deficient. Human GH is administered by daily injection. Most pituitary endocrinologists start at relatively low doses to avoid side effects and increase as needed.
DI therapy:Desmopressin is usually given in tablet or spray form (nasal tube or nasal spray). Hospitalized patients may be given desmopressin by injection.
See more here:
How Hypopituitarism is Treated | Learn More About ...
- Sheehan's syndrome - Symptoms and causes - Mayo Clinic - February 19th, 2021
- atrophy | Definition, Types, & Effects | Britannica - February 19th, 2021
- Hormone Replacement in Hypopituitarism Guideline Resources ... - February 14th, 2021
- World Alopecia Market Segmentation & Impact Analysis, by Gender, Application and Region - Featuring Profiles of Key Players Cipla Inc, Johnson AG,... - December 30th, 2020
- Global Alopecia Market is Forecast to Deliver a CAGR of 5.1% Between 2019 and 2027 - GlobeNewswire - December 14th, 2020
- Merck Announces KEYNOTE-598 Trial Evaluating KEYTRUDA in Combination With Ipilimumab Versus KEYTRUDA Monotherapy in Certain Patients With Metastatic... - November 13th, 2020
- Alopecia Market Analysis, COVID-19 Impact,Outlook, Opportunities, Size, Share Forecast and Supply Demand 2021-2027|Trusted Business Insights -... - November 10th, 2020
- Male Hypogonadism Market Projected to be Resilient During 2025 - The Market Feed - November 10th, 2020
- Alopecia Market Analysis, COVID-19 Impact,Outlook, Opportunities, Size, Share Forecast and Supply Demand 2021-2027|Trusted Business Insights - KYT24 - November 8th, 2020
- U.S. Food and Drug Administration Accepts for Priority Review Applications for OPDIVO (nivolumab) in Combination with CABOMETYX (cabozantinib) in... - October 23rd, 2020
- Man scared to return home after being stabbed and beaten by intruders in the middle of the night - Yorkshire Live - September 26th, 2020
- Disabled Sheffield man reveals horrific injuries after being stabbed in his own home - The Star - September 22nd, 2020
- BAVENCIO Pivotal Phase III JAVELIN Bladder 100 Results Published in The New England Journal of Medicine - PRNewswire - September 22nd, 2020
- Kristine Barnett: Indiana mum who abandoned 'adult' daughter who tried to kill her cleared of neglect charges - MEAWW - August 19th, 2020
- Global Alopecia Market was valued at approximately USD 2.40 billion in 2019, and is expected to generate revenue of around USD 4.45 billion by end of... - August 11th, 2020
- 20 Of The Most Shocking Plot Twists In Movies That We Never Predicted - ScoopWhoop - August 11th, 2020
- Global Alopecia Market 2020 | Analyzing The COVID-19 Impact Followed By Restraints, Opportunities And Projected Developments - Bulletin Line - August 2nd, 2020
- Diagnosis and Management of Pituitary Incidentaloma - Endocrinology Advisor - June 18th, 2020
- Male Hypogonadism Market Future Aspect Analysis and Current Trends by 2017 to 2025 - 3rd Watch News - May 21st, 2020
- Breakthrough Innovation in Cancer Care From EMD Serono Pipeline to Be Presented at ASCO 2020 - PRNewswire - May 18th, 2020
- Breakthrough Innovation in Cancer Care From EMD Serono Pipeline to Be Presented at ASCO 2020 - WFMZ Allentown - May 16th, 2020
- Hypopituitarism | Endocrine Society - April 13th, 2020
- Certain Types of Steroids Could Increase the Risk of Coronavirus - Myhealthyclick - April 13th, 2020
- EMD Serono and Pfizer Receive US FDA Breakthrough Therapy Designation and Submit Application for BAVENCIO for First-Line Maintenance Treatment of... - April 10th, 2020
- Corticosteroids With COVID-19 in Asthma, Allergies, and Arthritis Patients - MedicineNet - April 9th, 2020
- How the Sunflowers Children's Action Group has brought joy to poorly youngsters in lockdown - Grimsby Live - April 9th, 2020
- Patients on Steroids With COVID-19 Might Need Rescue Steroids - Medscape - April 6th, 2020
- Patients taking steroids with COVID-19 may need rescue steroids. - NewsDio - April 6th, 2020
- EMD Serono and Pfizer Provide Update on Phase III JAVELIN Head and Neck 100 Study - P&T Community - March 18th, 2020
- Is dwarf boy Quaden Bayles 18-year-old or just 9? Internet is divided and debate continues - International Business Times, Singapore Edition - February 28th, 2020
- 'Orphan' Prequel to Tell the Origins of 'Esther' - Bloody Disgusting - February 20th, 2020
- Acromegaly Treatment Industry 2020 Global Market Size, Demand, Growth Prospects, Key Insights, Top Companies and Forecast till 2025 - Instant Tech... - February 18th, 2020
- The motive within the serve of this man's suffering became once hiding in undeniable look - Invest Records - January 28th, 2020
- Male Hypogonadism Market Analytical Overview and Growth Opportunities by 2025 - Fusion Science Academy - January 17th, 2020
- Rare Skeleton Points to Compassion, Care, and Tragedy in Prehistoric China - Gizmodo - December 21st, 2019
- Acromegaly Treatment Industry 2019 Global Market Size, Demand, Growth Prospects, Key Insights, Top Companies and Forecast till 2025 - Market Research... - December 20th, 2019
- 5,000-Year-Old Human Found with 'Extremely Rare' Form of Dwarfism - Livescience.com - December 17th, 2019
- Acromegaly Treatment Industry 2019 Global Market Size, Demand, Growth Prospects, Key Insights, Top Companies and Forecast till 2025 - VaporBlash - December 5th, 2019
- Alopecia Market Outlook and Opportunities in Grooming Regions with Forecast to 2027 | CAPILLUS, Sun Pharmaceutical Industries, Cipla, Merck and Co,... - November 24th, 2019
- Look inside the old Natwest in Prescot after its total transformation - Liverpool Echo - November 2nd, 2019
- PRACTICALLY ACTIVE: Love your liver and it will love you back - Arkansas Democrat-Gazette - October 9th, 2019
- Male Hypogonadism Market Growth Opportunities and Dynamic Business by 2025 - NewsStoner - September 27th, 2019
- What causes prolonged menstrual bleeding? - The New Times - September 24th, 2019
- CHMP Adopts Positive Opinion for BAVENCIO (avelumab) Plus Axitinib for First-Line Treatment of Patients with Advanced Renal Cell Carcinoma -... - September 24th, 2019
- Pfizer Presents Scientific Advancements in Cancer Care at the ESMO Congress 2019 Highlighting Expanded Portfolio - Yahoo Finance - September 24th, 2019
- Acute Hypopituitarism: Overview, Diagnostic Considerations ... - May 29th, 2019
- Hypopituitarism | Endocrinology | Dartmouth-Hitchcock - May 2nd, 2019
- Hypopituitarism | Johns Hopkins Medicine - April 11th, 2019
- Hypopituitarism Symptoms & Causes | Boston Children's Hospital - March 6th, 2019
- Endocrine Diseases in Pregnancy | GLOWM - February 18th, 2019
- Non-Functioning Tumors (Endocrine-Inactive Tumors ... - January 29th, 2019
- Steroid Replacement Doses for Hypopituitary Patients ... - January 24th, 2019
- Hypopituitarism | UCLA Health - October 7th, 2018
- Hypopituitarism Disease Reference Guide - Drugs.com - October 3rd, 2018
- Hypopituitarism Treatment & Causes | Lurie Children's - October 3rd, 2018
- Hypopituitarism | You and Your Hormones from the Society for ... - August 23rd, 2018
- Panhypopituitarism: Practice Essentials, Pathophysiology ... - August 23rd, 2018
- Hypopituitarism | Lifespan - August 23rd, 2018
- OMIM Entry - # 146510 - PALLISTER-HALL SYNDROME; PHS - July 26th, 2018
- Hypopituitarism in Children | Children's Hospital of Philadelphia - July 12th, 2018
- What is hypopituitarism? | The Pituitary Foundation - July 12th, 2018
- Hypopituitarism - Diagnosis and treatment - Mayo Clinic - June 4th, 2018
- Hypopituitarism in Kids: Definition, Symptoms, Treatment - May 11th, 2018
- Hypopituitarism | Hormone Health Network - April 24th, 2018
- Hypopituitarism - Symptoms, Causes, Diagnosis and Treatment - Prime Health Channel - April 8th, 2018
- Hypopituitary: Hypopituitarism Causes, Symptoms & Treatment - March 26th, 2018
- Generalized Hypopituitarism - Endocrine and Metabolic ... - March 5th, 2018
- Hypopituitarism - Symptoms and causes - Mayo Clinic - February 28th, 2018
- Hypopituitarism: Causes, Symptoms, and Treatment - February 28th, 2018
- LABOKLIN (UK)| Genetic Diseases | Dogs| Dwarfism ... - February 8th, 2018
- Prevalence of Hypopituitarism in Veterans 42% A NEW ... - February 7th, 2018
- Pituitary Disorders - labtestsonline.org - January 7th, 2018
- Severe hyponatremia due to hypopituitarism with adrenal ... - September 20th, 2017
- Hypopituitarism | You and Your Hormones from the Society ... - August 21st, 2017
- The Pituitary Society | Glossary of Terms Related to ... - August 14th, 2017
- What Is Hypopituitarism (Dwarfism)? - Verywell - August 4th, 2017
- Hormone Replacement Therapy Market: Industry Players to Show High Growth Rate by 2024 - Monotone Critic - July 31st, 2017
- Hormone Replacement Therapy Market: Global Industry Analysis, Size, Share, Growth, Trends, and Forecasts 2016 ... - Digital Journal - July 31st, 2017
- Male Hypogonadism Market Deep Research Study with Forecast by 2025 - Digital Journal - July 12th, 2017
- Treatment of hypopituitarism - uptodate.com - May 22nd, 2017