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Archive for the ‘Hormone Clinic’ Category

Lorraine Keane reveals ‘scheduled sex’ during IVF battle took romance out of relationship – Dublin Live

Former Ireland AM presenter Lorraine Keane has told how scheduled sex during her IVF battle took the romance out of her relationship.

The screen and stage star said the scientific approach to making love put a strain on her and musician hubby Peter Devlins marriage.

But the 47-year-old revealed that with the right hormone balance shes bringing sexy back.

Mum-of-two Lorraine opened up on losing clumps of hair, breaking out in adult acne and having a low libido, as the gruelling perimenopause took its grip.

She said her failed IVF attempts were directly linked to her hormone imbalance and she counts herself lucky to have her daughters.

Lorraine told Dublin Live: I kept it to myself for all of the time that we thought it might happen.

It was really difficult to come out and talk about being perimenopausal. But then it made sense to come out and talk about the whole truth.

Maybe I didnt talk about doing IVF during it because I thought, If I do have a baby maybe I wont want to say thats how we conceived.

But then I got such an amazing reaction for opening up about the menopause, it gave me the confidence to speak out and to help other women who may have an opportunity to conceive and maybe their hormones are the reason that theyre not.

Id hate for them to go through three sessions of IVF for all of those reasons, because of the mental and physical harm that it does to you, your wallet as well.

The star admitted the gruelling IVF sessions were tough on her relationship.

She said: It takes the romance out of things, before you even do the business, youre looking at calendars and scheduling in time to have sex, its not very romantic.

Im sure most men are thinking, Id love that but when youre actually in it, the pressure of, Please God make this work it takes away the spontaneity completely.

But thank God myself and Peter always had two healthy babies to go back to.

I feel for people who dont have children, we could count our blessings with the two that we have.

Opening up on her hormonal imbalance, Lorraine said: If you are going to go through menopause then you will go through perimenopause first.

Its a milder version of full-blown menopause Im told.

For example, I havent had a hot flush, or I dont have any problems with my nether regions.

I know during menopause women have terrible pain there, especially during sex, but there is so much help out there, lots of options, whether it be natural, medical, even diet can help.

The symptoms I had were I did get night sweats before I started taking MenoMin and made a visit to endocrinologist Dr Mary Ryan to check my hormone levels.

Clumps of my hair fell out in the shower, it was all hormone related, I had extensions for ages but the worst was the hormonal breakouts, adult acne.

Now I feel balanced, like the 35-year-old me I sleep better (I was waking three to five times a night), my libido has returned, Ive less joint pain, no more hair loss, no hormonal breakouts, I feel brilliant.

Lorraine was approached to front the Cleanmarine brand and despite her initial shock at being approached, shes never looked back.

With perimenopausal symptoms starting when she was 37, she wished she knew her hormones were the main reason she couldnt add to her family. She said: I didnt realise it was something I could fix, maintain and control.

Myself and Peter would have loved to have had more children but we were in one of these situations that was unexplained infertility.

I found out I went into perimenopause very young, normally its 40-plus, I was 37 or 38 going into this.

There I was spending a fortune on IVF, emotionally, physically and mentally suffering through a few phases of it.

Neither one of us were infertile, so it could have been down to hormones and the fact I was in the perimenopause.

I felt low, no energy, very slow, I was annoyed with myself because Ive so much to be grateful for and then Id feel annoyed because I wasnt singing, whistling or being chirpy about life. I discovered taking the right supplements you can have perimenopause and menopause and still be sexy, its just hormones.

Lorraine is urging the public to help support Fashion Relief in aid of Oxfam at Dublins RDS on March 27 and 28.

She said: I travelled to Bangladesh to visit the refugee camp in 2019 and raised 203,000.

To know that theyll have clean safe drinking water and to have a health clinic on site because of Fashion Relief is incredible. Not even half of that will be needed for the camp and it will keep the camp running safely for another year.

The people dont want to be there, but they cant go back home as its unsafe, so at least while there, we know theyll be safe, healthy and educated, weve teachers on site too.

That was down to everyone giving their services and talents for free, the clothes on the day people donate pre-loved designer clothing, it doesnt always have to be designer. Boutiques, wholesalers and designers all donate, its an amazing day out, everything we dont sell goes back into the Oxfam shops.

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Lorraine Keane reveals 'scheduled sex' during IVF battle took romance out of relationship - Dublin Live

NHS Mental Health Director Claire Murdoch Warns Game Developers Of Loot Box Risks To Children – The Hear UP

Protein shakes have become rather essential in this modern era for people of different age groups. It does not just help you to build lean muscles and repair damaged ones, it also gives you the strength to carry out throughout the day without any loss of energy. There are several types of protein shakes in the market. Although all the brands claim to be one of the best in the market, it is not true all the time. Since it is a matter of your own health, it is important that you choose nothing but the best. Thus, TrueFit Lean Protein Shake is a good option for you.

RSP is one of the popular supplement companies that was started by a group of former student-athletes. During the initial days, the company used to concentrate only on bodybuilding products. However, with time, they shifted their focus to more general health supplements. The founders of the company state that they wish the company to become a lifestyle brand that customers can use in their everyday lives.

RSP has come up with several amino acid powder products in the past. However, TrueFit happens to be their flagship product. According to the makers, this protein shake provides users with an ideal balance of veggies, fruits, and high-quality protein, along with 9gm of carbs, dietary fiber, and healthy fats.

Every serving of these health supplements gives you 25gm of protein, 160 calories, 12gm of carbs comprising of 2gm of sugar and 8gm of fiber, and 3gm of fat. Your body will also get approximately 9% of your daily sodium and 20% of your daily cholesterol supply from each scoop. When you talk about the minerals and vitamins in the protein shake, TrueFit comprises of roughly 30% of the daily recommended dose of vitamins and minerals for an adult. This includes vitamins A, B, C, D, E, magnesium, and biotin.

The protein content in TrueFit Lean Protein Shake (see full details at comes from whey isolate and concentrate. The different flavorings of the product also come from natural flavors, cocoa, artificial sweeteners such as sucralose, and stevia. However, the product is free from artificial flavors, colors, and preservatives. Even the content of artificial sweeteners is about less than 0.1gm in each scoop.

The fiber in this product comes from 8.5gm of prebiotic soluble fiber, as well as, from sweet potato powder. It also contains 1gm of a mixture of different types of vegetables and fruits such as berries, broccoli sprouts, carrots, and tomato to name a few. The presence of 7 different digestive enzymes, such as bromelain, protease, lipase, papain, amylase, cellulose, and lactase, as well as, 1 billion probiotic bacteria ensure proper digestive health for you.

From a first timers point of view, it is a good thing that the TrueFit Lean Protein Shake comes with a good list of ingredients that focus on your gut. The pre and probiotics, digestive enzymes, and fiber ensure that your digestive system does not take a beating when you have the protein shake. These ingredients also make sure that all the essential nutrients get absorbed in your system properly, making it a great choice for those of you who suffer from digestive issues.

The high fiber content results in a low amount of net carbs in the shake, which along with low-fat content makes it a great meal replacement. In other words, it is more than a mere protein shake for you. According to the makers, one scoop of the protein shake will give you everything that your body needs in terms of nutrition. It will give you a balanced diet and also ensure that you remain full for quite some time.

However, there are some nutrients that are missing in this product. Nutrients such as choline and vitamin K are missing out in this supplement, which does not make it a nutritionally complete health drink. It even lacks zinc, iron, and potassium and contains a losing percentage of calcium. These are essential nutrients for your health and missing out on these nutrients can be dangerous in the long run.

In short, it can be said that RSP TrueFit Lean Protein Shake is rather good as a high fiber protein nutritious shake that has special attention towards your digestive system. Although it is pretty low in carbs, which is a good thing, it is also quite low in iron, fat, and potassium, which may not be that good for your health.

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NHS Mental Health Director Claire Murdoch Warns Game Developers Of Loot Box Risks To Children - The Hear UP

Health Department announces services for the week of Jan 27 – Teutopolis Press-Dieterich Gazette

The Fulton County Health Department has scheduled the following health clinics and services.

CANTON The Fulton County Health Department has scheduled the following health clinics and services. Please call the number listed with each service for an appointment or more information.

Maternal child health: Health screenings, WIC nutrition education and supplemental food coupons for women, infants and children. To make an appointment or for more information call 647-1134 (ext. 254). For Astoria clinic appointments call 329-2922.

Canton - Clinic - Monday, Jan 27 - 8-4 - Appt needed

Canton - WIC Nutrition Education - Tuesday, Jan 28 - 8-4 - Appt needed

Astoria - Clinic, WIC Nutrition Educ. - Wednesday, Jan 29 - 9-3 - Appt needed

Canton - Clinic - Thursday, Jan 30 - 8-4 - Appt needed

Adult Health Immunizations: Various vaccines are available. There is a fee for immunization administration. Medicaid cards are accepted. To make an appointment or for more information call 647-1134 (ext. 254).

Other times available by special arrangement at Canton, Cuba and Astoria.

Blood Lead Screening: Blood lead screenings are available for children ages one to six years. A fee is based on income. To make an appointment or for more information call 647-1134 (ext. 254). For Astoria appointments call 329-2922.

Family Planning: Confidential family planning services are available by appointment at the Canton office for families and males of child-bearing age. Services provided include physical exams, pap smears, sexually transmitted disease testing, contraceptive methods, pregnancy testing, education and counseling. Services are available to individuals of all income levels. Fees are based on a sliding fee scale with services provided at no charge to many clients. Medicaid and many insurances are accepted. After hours appointments are available. To make an appointment or for more information call the 647-1134 (ext. 244). *Program funding includes a grant from the US DHHS Title X.

Pregnancy testing: Confidential urine pregnancy testing is available at the Canton and Astoria offices. This service is available to females of all income levels. A nominal fee is charged. No appointment is needed. A first morning urine specimen should be collected for optimal testing and brought to the health department. Services are provided on a walk-in basis on the following days each week:

Canton: Every Wednesday & Thursday, 8-3:30 (for more information call 647-1134 ext. 244)

Astoria: Every Wednesday, 9-2:30 (for more information call 329-2922)

Womens Health: A womens clinic for pap tests, clinical breast examinations and vaginal examinations is available by appointment. There is a nominal fee for this service. Medicaid cards are accepted. Financial assistance is available for a mammogram. Cardiovascular screenings may be available to age and income eligible women. To make an appointment or for more information call 647-1134 (ext. 244).

Mammograms: Age and income eligible women may receive mammograms at no charge. Speakers are available to provide information to clubs and organizations. For more information or to apply for financial assistance, call 647-1134 (ext. 254).

Mens Health: Prostate specific antigen (PSA) blood tests are available for men for a fee. To make an appointment or for more information call 647-1134 (ext. 224).

Canton - Clinic - Monday, Jan 27 - 8-12 - Appt needed

Sexually Transmitted Disease (STD) Clinic: Confidential STD and HIV testing services are available by appointment to males and females at the Canton office. Services include physical exams to identify STDs, a variety of STD testing, HIV testing, education, counseling, medications and condoms. There is a nominal fee for services. Services are available to individuals of all income levels. Medicaid cards are accepted. To make an appointment or for more information call 746-1134 (ext. 224).

HIV Testing and Counseling: Confidential HIV testing and counseling services are available by appointment through the sexually transmitted disease (STD) clinic at the Canton office. To make an appointment or for more information call 647-1134 (ext. 224).

Tuberculosis (TB) Testing: TB skin tests are available at no charge by appointment. To make an appointment or for more information call 647-1134 (ext. 254).

Blood Pressure Screenings: The Fulton County Health Department provides blood pressure screenings at no charge on a walk-in basis during the following times:

Canton - Screening - Monday, Jan 27 - 8-5 - Walk in/Room 108

Cuba - Screening - Monday, Jan 27 - 8-12 - Walk in

Astoria - Screening - Wednesday, Jan 29 - 9-12 - Walk in

Health Watch Wellness Program: The Health Watch Program provides low cost lab services. Through this program adults can obtain venous blood draws for a variety of blood tests. Blood tests offered without a doctors order Comprehensive Metabolic Panel (CMP), Complete Blood Count (CBC), Lipid Panel, Prostate Specific Antigen (PSA) test, Hepatitis C test, and Thyroid Stimulating Hormone (TSH). A wide variety of blood tests are also available with a doctors order. There is a charge at the time of service. To make an appointment or for more information call 647-1134 (ext. 254).

Canton - Clinic - Monday, Jan 27 - 8-12 - Appt needed

Dental Services: The Dental Center offers a variety of basic dental services to children and adults. An appointment is needed. Medicaid and Kid Care cards are accepted. To make an appointment or for more information call 647-1134 (ext. 292).

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Health Department announces services for the week of Jan 27 - Teutopolis Press-Dieterich Gazette

Sleep cages and ice baths: The extreme lifestyle of local biohackers – Minneapolis Star Tribune

In the predawn darkness, you can see an eerie red glow shining from the windows of the Hudson, Wis., home of Thaddeus Owen and his fiance, Heidi Sime.

The couple are awake, having slept in their Faraday cage a canopy over their bed that blocks electromagnetic fields like the Wi-Fi signals or radiation from cellphone towers, which they believe are harmful.

Their primal sleeping environment also has special pads under the bed that are supposed to mimic the effect of sleeping on the ground under the influence of the Earths magnetic field, thus combating Magnetic Field Deficiency Syndrome.

Their house is bathed in red light because they think white incandescent, LED and fluorescent lighting robs them of sleep-regulating melatonin hormones. They wear special sunglasses indoors for the same reason, blocking the blue light from computers, cellphones or televisions when its dark outside.

Their morning routine includes yoga in a shielded, infrared sauna designed to create an EMF-free ancestral space, and putting tiny spoonfuls of bitter white powders under their tongues. These are nootropics, so-called smart drugs, which are supposed to improve focus, mood or memory.

When day breaks, they go out in their yard and face the rising sun Thaddeus in shorts and no shirt, Heidi in a sports bra and yoga pants doing Qigong in the snow and 25-degree air.

Getting early-morning sunlight, they believe, will correctly set the circadian rhythm of their bodies. Exposing their skin to the freezing temperatures, they hope, will help release human growth hormone, stimulate their immune system and trigger the body to burn fat to heat itself.

Forget Blue Zones. This is what your morning looks like if youre biohacking your way to an optimal you.

Biohacking is a DIY biology movement that started in Silicon Valley by people who want to boost productivity and human performance and engineer away aging and ordinary life spans. Think of it as high-tech tinkering, but instead of trying to create a better phone, biohackers are trying to upgrade to a faster, smarter, longer lasting, enhanced version of themselves.

Owen, 44, describes it as a journey of self-experimentation, using practices that are not talked about by mainstream media and your family doctor. His aim is to combine the latest technology and science with ancient knowledge to modify his environment, inside and out.

My entire goal is to basically age in reverse, he said.

Aiming for supernormal

Owen, who is from New York, studied chemical engineering in college. He worked for Procter & Gamble, helping to create beauty care products, and for pharmaceutical firms, developing manufacturing processes.

Now he works from home, managing worldwide product regulations in the sustainability department for office furniture company Herman Miller. But he moonlights as a biohacking guru.

He started a Twin Cities biohacking Meetup group that organizes weekly cold-water immersions at Cedar Lake in Minneapolis. Hes given a TEDx talk urging audience members to wear blue-light-blocking glasses indoors at night.

Hes helping to organize a Cold Thermogenesis and Heat Shock retreat at the end of next month in Pequot Lakes, Minn., where 50 people will pay up to $2,300 to spend four days going on shiver walks, drinking Bulletproof coffee and plunging into ice water.

He founded the website and he and the 45-year-old Sime (who also goes by the name Tomorrow) run a website called, where they market biohacking products like red light panels, a baby blanket that blocks EMF radiation and a $5,499 Faraday cage sauna thats the same type used by Twitter founder Jack Dorsey.

Owen said he relies on tons of research to support avoiding blue light at night and the healing properties of the early morning sun.

The Harvard Health Letter, for example, said that blue light from devices, LED and compact fluorescent bulbs can throw off the bodys circadian rhythm, affect sleep and might contribute to cancer, diabetes, heart disease and obesity. Some studies have shown that exposing people to cold temperatures burns calories and repeated cold-water immersions might stimulate the immune system.

And those infrared saunas? They dont appear to be harmful and maybe they do some good, according to Dr. Brent Bauer, an internal medicine expert at the Mayo Clinic.

But being healthy really doesnt need to be that complicated, according to Dr. Michael Joyner, a human performance specialist at the Mayo Clinic.

All these things sound great, Joyner said of the biohacks. Theres a ring of what I call bioplausibility to them.

But Joyner said its often hard to find evidence that biohacking practices actually work and that most Americans would be healthier if they just followed basic advice.

You need to go for a walk, not smoke, not drink too much, dont eat too much, he said.

But Owens goal is not to be merely healthy.

I want my biology to be shifted to that supernormal range, where Im optimally healthy, he said.

Moving into the mainstream?

When he started biohacking about 12 years ago, Owens goal was to improve his sleep. As a competitive athlete, he was fit, but he had problems with anxiety and insomnia.

So he started wearing special glasses to block blue light. His co-workers used to think he was odd. Now Owens company is asking him for advice on what kind of lighting should be used in work settings to keep employees healthy. And his sleep and anxiety problems have gone away.

I went from being the weird guy to being consulted, he said.

We all sort of watch what he does, said Gabe Wing, director of sustainability at Herman Miller and Owens boss. Wing said Owen has influenced some co-workers to try blue-light-blocking tools. But no one at the Michigan-based company is going outside shirtless in the winter.

Still, more people are biohacking. When Owen first got into it, he didnt know of any other biohackers in the Twin Cities. Now there are more than 500 people in the Biohackers Twin Cities Meetup group.

Susan Eiden regularly gets advice from Owen. The Minneapolis resident said using red lights at home has drawn comments from neighbors, but the lights combined with blue-blocking glasses and turning off the Wi-Fi at night have improved her sleep.

While many biohacks seem odd now, Owen is convinced that some of them will become common practices.

This whole blue light thing, its not going away, he said. More research comes out every day and its becoming more mainstream. And using nootropics is growing bigger and bigger every day, he said.

Owen takes supplements, some of which are considered prescription drugs in Europe and Russia, like phenylpiracetam, which is said to have boosted stamina among Soviet cosmonauts. Other preclinical compounds he and Sime use are in a regulatory gray area in the United States. Nootropic developers give them supplements that arent on the market yet because theyre biohacking influencers.

Were like lab rats. They send us stuff. We try it out, Sime said.

All for longevity

Owen and Sime have five of their children, ages 8 to 17, living with them. The kids wear blue-light-blocking glasses when they watch TV, but theyre OK with it, the couple said. Some of the kids have made videos or given talks to peers about the benefits of the glasses.

I think cellphone radiation is going to be the new lead, asbestos and smoking, said Owen, who turns his Wi-Fi off at night, keeps his cellphone in a special Faraday pouch when he sleeps and sometimes wears radiation-proof underwear.

(The National Institute of Environmental Health Sciences says scientific evidence has not conclusively linked cellphone use with any adverse human health problems, although scientists admit that more research is needed.)

Owens diet isnt typical, either.

Hes been a vegan and a vegetarian. Now he eats what he describes as a local, seasonal diet: local vegetables, fruits, nuts and honey during the growing season. Thats followed by a high-fat, low-carb ketogenic diet in late fall and early winter. Then an all-carnivore diet in late winter, including animals hes raised at a friends farm.

One of the few white light bulbs he has in his house is pointed at the stove because in red light, its hard to tell if meat is cooked.

He also consumes ceremonial grade cacao, coffee with collagen peptides and chocolate ghee and homemade sauerkraut thats fermented and subjected to special music that has the frequency of love.

Those are living microbes, so I infused them with a love frequency to make them happy and healthy, said Owen, who has a masters degree in holistic nutrition.

While he used to do marathons and triathlons, he now exercises for longevity rather than competition, with high-intensity training, weights, racquetball and cross-country skiing.

If its too cold to be barefoot when he goes out in the morning, hell put special straps on his boots to create a conductive connection between his body and the Earth.

Its a practice called grounding or Earthing thats supposed to allow electrons to pass between the Earth and his body to reduce inflammation and neutralize free radicals. Gwyneth Paltrow swears by it, according to an article on

Owen doesnt have a particular longevity goal, unlike biohacker and Bulletproof Coffee founder Dave Asprey, who has said he wants to live to at least 180.

Owen just wants to be healthy and independent for as long as he lives.

I want to maximize the health of my biology to what its capable of, he said. I want to live the best life that I can. I want to be happy. And I want to have a body and a mind that does the things I want them to do.

Sleep cages and ice baths: The extreme lifestyle of local biohackers - Minneapolis Star Tribune

Solving Depression and Anxiety in Veterans – Newsmax

Between 2000 and 2012, the Department of Veterans Affairs reported a 327% increase in anxiety disorders among military members. A recent study suggests that this may be due to the discovery of a so-called "worry gene." Researchers from Yale University in New Haven, Connecticut, and the University of California in San Diego analyzed the genes of 200,000 U.S. veterans and identified six genetic variants linked to anxiety a discovery that may help explain why anxiety and depression often go hand in hand.

The study authors hailed their finding as "the richest set of results for the genetic basis of anxiety to date." But leading psychologists say that while genes may load the gun, it's most often environment that pulls the trigger on mental health disorders.

According to Mental Health First Aid, 20 veterans die by suicide each day. Over 30% of active duty and military personnel deployed in Iraq and Afghanistan have a mental health problem requiring treatment, but only half of these returning veterans receive the care they need.

"We should spend as much money on helping these veterans re-enter their civilian lives as we do in training them for the military," Dr. Terry Lyles, Ph.D., an internationally recognized expert on dealing with trauma and stress, tells Newsmax. "The study points the finger at genetics on why our military personnel have mental health issues. However, we basically all have the same genetic patterns but when threatened with violence, danger, and combat stress, we release levels of cortisol, the stress hormone, that drains our bodies of the natural resources to deal with that constant bombardment.

"Cortisol literally eats serotonin, the hormone that helps regulate mood and social behavior. So, when these veterans are subjected to constant threats, improper nutrition, lack of sleep, and sunlight it's no wonder they become rewired to exhibit anxiety and depression."

Lyles, known as America's "Stress Coach," uses highly specialized techniques to help veterans and other individuals such as the rescue workers at Ground Zero and those in the tsunami-torn area in Asia to help channel mental negativity and chaos into more productive and positive pathways.

Dr. Lois Mueller, a clinical psychologist from Tampa who worked at the U.S, Department of Veterans Affairs, Outpatient Clinic for 10 years, tells Newsmax, that people with a genetic predisposition toward anxiety will have a 10-fold increased risk of developing a mental disorder when being placed in a combat situation where people around you are wounded or dying.

"Whatever they came with genetically was certainly affected by their environment," she says. "The proof of impact of combat would be to compare vets before being in the military and five years after combat. Don't forget, a lot more were traumatized not only by combat itself but also by associated military duties such as picking up and bagging bodies or delivering the folded flags to mothers here in the States.

"My experience with vets with PSTD is very often people who were calm and worry-free prior to combat ended up anxious and fearful after leaving the military. Early treatment can make a difference but length of exposure to combat can make it very difficult to eliminate the problem. We are still learning about treatment techniques."

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Solving Depression and Anxiety in Veterans - Newsmax

Nanoparticle Therapy Shows Promise With Breast Cancer – UMB News

Researchers at theUniversity of Maryland School of Medicine (UMSOM) developed a new nanoparticle drug formulation that targets a specific receptor on cancer cells and appears to be more effective than a standard nanoparticle therapy currently on the market to treat metastatic breast cancer, according to a study published today in the journal Science Advances. The new DART (decreased, non-specific adhesivity, receptor-targeted) nanoparticles bypass healthy cells and tissues and bind to tumor cells, dispersing evenly throughout the tumor while releasing the chemotherapy drug paclitaxel.

The marketed drug Abraxane, a nanoformulation containing paclitaxel that is currently used to treat women with aggressive breast cancer, is an effective agent, but it was not designed to selectively deliver paclitaxel to only the cancerous cells within the body, said study corresponding co-author Jeffrey Winkles, PhD, a professor of surgery at UMSOM. Our DART nanoparticle specifically targets the Fn14 receptor found abundantly on breast cancer cells; it uses this receptor to gain entry through the plasma membrane and deliver the drug to destroy the cancer. Winkles group discovered the Fn14 receptor and described its potential as a target for new therapeutics more than a decade ago.

For this study, UMSOM researchers engineered and tested a new therapeutic nanoparticle platform to deliver the drug paclitaxel to treat triple-negative breast cancer. About one in five women with breast cancer have this type of aggressive tumor, which is particularly difficult to treat; these cancers lack receptors commonly expressed by most breast cancer cells, like hormone receptors, for which effective drugs have been designed. But many triple-negative breast cancers express high levels of Fn14; indeed, most solid tumor types, including lung, prostate, and colorectal cancer, overexpress this cell surface receptor.

After much initial hype and some disappointments in the field, nanoparticle delivery systems for cancer treatment are starting to show real promise for patients, said study co-author Graeme Woodworth, MD, professor and interim chair in the Department of Neurosurgery at UMSOM. We established a proof-of-concept with this study, outlining the design of an optimized nanoparticle delivery system that balances the specific binding to cancer cells while minimizing non-specific, off-target binding to other cells in a very fine-tuned way.

To accomplish this, the research team attached a monoclonal antibody called ITEM 4 to the surface of the nanoparticle because it specifically binds to Fn14, providing a key to unlock entry into the cancer cell. The surface of the nanoparticles also was coated with polyethylene glycol to keep them circulating through the bloodstream and lymph system until they reached the tumor and to prevent them from being quickly flushed out of the body.

Many drug delivery carriers exhibit non-specific binding to healthy cells and tissues in addition to the diseased cells they are targeting, which often leads to unintended side effects or toxicities, said study corresponding co-author Anthony Kim, PhD, associate professor of neurosurgery and pharmacology at UMSOM. This DART nanoparticle platform has unique capabilities to improve therapeutic delivery to difficult-to-treat locations within the body while also allowing us to potentially increase the maximum tolerated dose of the encapsulated drug without increasing side effects to patients.

The researchers filled their optimized DART nanoparticle formulation with paclitaxel and tested it against Abraxane (the marketed nanoparticle that also contains paclitaxel) in animals with triple-negative breast cancer tumors. In one set of experiments, the nanoparticles were delivered to mice harboring breast tumors grown above the natural breast region. They found the DART formulation led to a significantly increased median overall survival (68 days) compared to Abraxane treatment (45 days). They also saw a clear benefit to using the DART nanoparticles when they compared the treatments again in animals that harbored breast tumors implanted in the brain (akin to a metastatic brain tumor).

This is a compelling finding and significant step forward in the use of nanoparticles to treat cancer, said UMSOM Dean E. Albert Reece, MD, PhD, MBA, the John Z. and Akiko K. Bowers Distinguished Professor and University of Maryland, Baltimore executive vice president for medical affairs. It fits squarely with our School of Medicines mission to advance the field of potentially lifesaving therapies for patients with the most difficult to treat cancers.

The UMSOM researchers are members of the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center. A former PhD student, Jimena Dancy, PhD, and a former postdoctoral fellow, Aniket Wadajkar, PhD, are listed as co-first authors on the publication. Researchers from the Translational Genomics Research Institute in Phoenix, Ariz., and the Mayo Clinic Arizona in Scottsdale, Ariz., also contributed to the work.

This study was primarily funded by the National Institutes of Health.

Future research includes testing the DART therapy in other cancer types, including an aggressive form of brain cancer called glioblastoma and developing a similar version of the nanoparticle designed to work specifically in humans. This would involve using a humanized antibody on the surface of the nanoparticle and scaling up the formulation. The researchers recently received a grant from the TEDCO Maryland Innovation Initiative Commercialization Program to move forward with efforts to adapt their nanoparticle system and eventually test the treatment in cancer patients.

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Nanoparticle Therapy Shows Promise With Breast Cancer - UMB News

Endometriosis and cannabis: THC improves symptoms – Health Europa

Endometriosis is a painful condition where the lining of the uterus grows on other parts of the organ such as the fallopian tubes. The new study, published in eLife, shows initial results from treating endometriosis in mice with cannabinoids suggesting they can alleviate symptoms of the disease.

The researchers say this new finding will pave the way for further clinical research.

The findings have led to the start of a clinical trial in collaboration with the Gynecology Service of the Hospital Clinic of Barcelona, Spain. The trial will evaluate the possible benefits of the naturally occurring cannabinoid 9-tetrahydrocannabinol (THC; the main psychoactive constituent of the cannabis plant) in women with endometriosis.

Endometriosis is a common, chronic and painful disease caused when the lining of the womb the endometrium grows outside of the womb cavity. These growths affect reproductive organs and can cause pain, infertility, anxiety, depression and result in a considerable impact on quality of life. Treatment options include surgery or hormone therapy, but these are not always effective and often have significant side-effects.

Rafael Maldonado, Professor at the University Pompeu Fabra of Barcelona, Spain, said: With a lack of effective treatments, women with endometriosis usually rely on self-management strategies like dietary changes or exercise. Although cannabis comes with a large number of potential side effects, its medicinal properties could provide pain relief in endometriosis and other conditions.

Since medical THC is available in some countries, the findings of our study may be of interest for gynecologists and pain specialists who manage the treatment of women with endometrial pain.

The team studied mice with endometrial implants in their pelvis to mimic endometriosis in humans. Those with the implants were more sensitive to pain in their pelvis that can also be associated with emotional and cognitive alterations similar to symptoms seen in some women with endometriosis.

The team next found that mice with endometriosis had similar anxiety-like symptoms experienced by some women with the condition. This was measured by the amount of time the animals spent in open areas of a maze, as those with higher anxiety levels tend not to explore too far. However, their experiments could not reveal whether THC had any significant effects in treating this anxiety.

As endometriosis can be known to impair cognitive function in some women, the team also studied memory performance in the mice. They provided the animals with two identical objects and allowed them to become familiar with them. They then replaced one of the objects and timed how long the mice spent exploring the new versus familiar object, to give an indication of what the animals remembered.

The team found that memory was impaired in the mice with endometriosis compared with those that did not have the condition. However, mice treated with THC did not show this impairment, suggesting that THC may have a protective effect.

Finally, the team studied the effects of THC on the endometrium inside and outside of the womb, and found that mice with endometriosis treated with THC for 32 days had smaller endometrial growths.

First author Alejandra Escudero-Lara, a PhD student at the University Pompeu Fabra of Barcelona, said: Together, our findings show that THC limits the development and symptoms of endometriosis in an experimental model, and highlight the interest of conducting further research to ensure the safety and beneficial effects of this treatment in women with endometriosis.

Continued here:
Endometriosis and cannabis: THC improves symptoms - Health Europa

Get Rid of Stubborn Belly Fat With 9 Expert Backed Tips – Men’s Health

Stubborn belly fat is more than just an annoyanceit can be dangerous. That's because stomach fat is visceral and surrounds vital organs such as the pancreas and intestines, says Rachel Stahl, R.D. at Weill Cornell Medicine.

It's also biologically active, meaning this type of fat changes the normal balance of hormones and can cause metabolic problems.

"They are not just standard cells storing fat," Stahl tells Men's Health.

Excess belly fat could also be a sign that you have too much fat surrounding your heart, liver, and kidneys, says endocrinologist Dr. Rasa Kazlauskaite, M.D. at Rush University Medical Center in Chicago, IL. When this happens "You are that much closer to developing diabetes," Kazlauskaite tells Men's Health.

So how much belly fat is too much?

Guys who have a waist circumference greater than 40 inches are at a higher risk of diabetes and heart disease, according to the National Institute of Health.

Measure around the middle of your waist, just above the hipbones, using a tape measure, advises the NIH.

Although losing belly fat isn't easy, there are ways to reduce your waistline:

Unfortunately, you can't force fat reduction in one area of your body, says Dr. W. Scott Butsch, M.D., and Director of Obesity Medicine at the Cleveland Clinic.

Instead, you'll want to focus on reducing overall calories, Butsch tells Men's Health.

"Weight loss in general should lead to a decrease in belly fat," he says.

Men's Health

Brain scans show that protein lowers activity in regions of the brain that stimulate food cravings. Protein also increases hormones that make you feel satiated, so you feel fuller for longer periods of time.

They're nutrient dense and provide plenty of fiber, meaning you'll get full on fewer calories. Load up half of your plate with vegetables, or begin every meal with a salad.

Kazlauskaite says guys who want to reduce belly fat should watch how much alcohol they consume. Aside from the obviousempty caloriesalcohol needs to be metabolized by the body, which briefly stops fat burning, she says.

Losing weight shouldn't be your only motivation to hit the gym. And exercise doesn't burn as many calories as you may believe. However, paired with a healthy overall diet, a regular workout routine can help you maintain a calorie deficit.

Clinically, Butsch says many of his patients notice a decrease in belly fat when they incorporate strength training. In fact, obese adolescents who incorporated both aerobic and strength training into their workouts lost the highest amounts of visceral fat, according to a 2014 study published in the Journal of Sports Sciences.

Sugar from juice and sodas are rapidly absorbed into the bloodstream, which spikes insulin, says Kazlauskaite. There's no evidence that these beverages actually cause obesity. However, studies show that frequently drinking sugar-sweetened beverages is linked to weight gain, obesity, and type 2 diabetes, according to the Centers for Disease Control & Prevention.

Eating an apple is different from a drinking a glass of apple juice, explains Kazlauskaite.

That's because you consume more nutrients like fiber when you consume the food in its natural form, she says. Plus, the process of chewing and consuming the food more slowly can help keep you full. "When you eat an apple, you eat slower," she says. "Your body has more time to digest it."

Cortisol, known as the stress hormone, is linked to a higher percent of belly fat and weight gain. In fact, people who have high levels of cortisol for long periods of time are more likely to develop abdominal obesity, according to a 2018 review of studies published in Current Obesity Reports.

Butsch says simple activities like yoga, meditation, or simply avoiding conflict can help keep your waistline trim.

"I think even just taking the higher road in an argument [helps]," he tells Men's Health.

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Get Rid of Stubborn Belly Fat With 9 Expert Backed Tips - Men's Health

Buses and Uncertainty –

BY Mary E. Burman

The table is loaded with food and the conversation is freewheeling with lots of laughter. Suddenly I remember that I have metastatic breast cancer. I'm feeling generally good with few side effects from my current treatment that hopefully will keep the rogue cells in my bones. At times like this, I can forget that I have metastatic breast cancer which will most likely cause my death. When that will happen is unknowable, and uncertainty is now a constant part of my life. Of course, all of us face uncertainty.

As the saying goes, anybody can walk out the door, get hit by a bus and be dead in seconds. However, as someone with a metastatic disease said, "The only thing I can think of is that I'm going to die. And that's the one certainty that I have, and I know people say () you could cross a street and be run over by a bus. But you live your life not thinking about it. I have to deal with it. My bus is here. All the time. And my bus is outside the door every morning and uncertainty is always with me.

For me, uncertainty manifests itself in several ways. There is a lot of ambiguity about my breast cancer which is "atypical" starting out as hormone positive but is now probably triple negative. It is not as aggressive as I was initially diagnosed with breast cancer 10 years ago. That makes the future unpredictable since most studies don't capture the outcomes for someone like me who is a healthy 60-year-old with an atypical cancer. While metastatic breast cancer is unfamiliar to me, my family has experienced a rare form of ataxia that has resulted in the death of several siblings for most of my adult life I've wondered whether I'd get it. Returning to the bus metaphor, while I was thinking Bus #9 (the ataxia bus) would hit me, it turned out to be Bus #3 (the breast cancer bus) resulting in a new and different uncertainty.

The feeling of uncertainty waxes and wanes and is stressful, fatiguing, intrusive, unending and isolating. Ultimately, uncertainty in metastatic breast cancer is not something you get past. It's always there waiting for the results of tests, figuring out the best treatment, wondering about prognosis and feeling anxious about costs of care. However, paradoxically, uncertainty leaves the door open for hope. Persons with metastatic breast cancer live in two worlds that of uncertainty and that of hope. My future is not written in stone because there is no way of knowing if I will live 2 years or 15 years. Consequently, that leaves space for envisioning the future, e.g., hope for time with my family, hope for being able to accomplish some things, and hope for new treatments.

Simultaneously living with uncertainty while embracing hope is not easy but it can be done. Arthur Brooks explores career transitions in the Atlantic magazine in an article entitled "Your professional decline is coming (much) sooner than you think: Here's how to make the most of it". While not about living with metastatic breast cancer, it a useful framework for living with uncertainty.

He promotes four different strategies for living well. First, jump which means focusing on what is most important in our personal and professional lives and walking away what isn't important. For me that meant stepping out of my administrative roles at work and downsizing to a much smaller and more manageable house and yard. Second, we should find ways to serve and help others. For me, I have renewed my volunteer work for a nonprofit clinic in my community, which provides me much satisfaction. Third, worship by exploring our own spiritual self and I've found great joy in reading, thinking and exploring new realms of spirituality. Finally, Brooks advocates that we connect dedicating time to meaningful and purposeful relationships.

Connecting and reconnecting with others who are comfortable with metastatic breast cancer has been extremely beneficial to me. Ultimately, the bus doesn't leave my street, but it doesn't have to impact my daily life which can be filled with hope, meaningful activities, and relationships despite the uncertainty.

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Buses and Uncertainty -

Breakthrough diabetes insulin drug developed with help from Buffalo – Buffalo News

Some people watch what they eat. Paige and Tanner Szczesekhave to watch when they eat.

The two children, ages 6 and 2, from Cheektowaga, have Type 1 diabetes. Like others with their condition, they must take extra insulin before meal and snacks. It takes time to work. Eat too soon, and blood sugar can climb dangerously high a constant worry for their mother, Ashley.

My biggest goal is that my children can just feel like children, she said.

Thanks to a new drug developed with an assist in Western New York, they have more of a chance.

The Food and Drug Administration last month approved of a drug that brings researchers a step closer to developing an artificial pancreas that will provide fast-acting insulin in proper amounts at just the right time for those with diabetes.

Fiasp, made by Novo Nordisk, starts working in 2 minutes, hits full force within 10 minutes and even can be taken shortly after someone withdiabetesstarts eating.

Previous fast-acting insulins took at least two or three times as long to do that job.

The newest drug has been available to adults since 2017, but the Food and Drug Administration wanted testing on children before making it available to them. More than 700 children in 17 countries participated in the clinical trial, including five children ages 13 to 17 who have been patients in the diabetes centers at UBMD Pediatrics and next door at Oishei Childrens Hospital on the Buffalo Niagara Medical Campus.

This was a big commitment for the families, said Dr. Kathleen E. Bethin, a clinical professor in the Department of Pediatrics in the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, and a physician at both diabetes centers. The kids were in the study for almost a year. There were a lot of extra blood draws and more blood sugar checks than are typically required.

Fiasp brings diabetes researchers closer to mimicking a closed-loop system that uses a glucose monitor, continuous insulin infusion pump and other technologies to allow people whose bodies dont make insulin to live like those whose do.

The new fast-acting insulin drug Fiasp boosts the prospects for a closed-loop insulin system often referred to as "an artificial pancreas," diabetes researchers in Buffalo and elsewhere say. (John Hickey/Buffalo News)

The goal in the diabetes field is to develop insulin analogs that behave more like natural insulin, which is rapid on, rapid off, meaning its quickly released, then quickly dissipates, said Dr. Lucy D. Mastrandrea, chief of the Division of Endocrinology/Diabetes at UBMD Pediatrics and medical director for the Oishei Childrens Hospital Diabetes Center. Part of the reason this drug was developed was to have a better timeline of action thats closer to natural insulin.

The body breaks down carbohydrates into blood sugar to use for energy. Insulin is a hormone needed to bring glucose from the bloodstream into human cells. When blood sugar gets too low, the process breaks down and can lead to learning challenges, seizures, loss of consciousness and death. When it spikes, especially often and over time, complications include limb amputation, heart and kidney disease, and stroke.

For those without diabetes, the pancreas, liver and other organs work together to automatically and seamlessly produce insulin and adjust levels as needed.

Type 2 diabetes is diagnosed when the body doesnt use insulin properly. It often can be managed through a combination of healthy eating, regular exercise and oral medications. Sometimes, insulin also is needed.

Those with Type 1 diabetes produce no insulin. They need to inject manufactured basal insulin to maintain levels throughout each day, load carbs or take medication when blood sugar levels get too low, and add fast-acting insulin to lower them when blood sugar levels climb.

Nearly 18,000 new cases of Type 1 diabetes are diagnosed each year. The majority of children have Type 1, while the majority of those diagnosed in adulthood have Type 2.

Our goal is to keep them in as best control as possible during their childhood years, so that they're not running the risk of dealing with complications when they're in their 20s and 30s, Mastrandrea said.

Drug-maker Eli Lilly engineered the first human-derived insulin, Humulin, in 1981. The company in 1996 developed a faster-acting insulin, Humalog, which is still routinely used. NovoLog and Apidra are among other brands that can lower blood sugar within 20 to 30 minutes after they are injected through a needle or an insulin pump, said Dr. Paresh Dandona, a leading international diabetes researcher, head of the Western New York Center of Diabetes-Endocrinology in Amherst and distinguished professor and chief of endocrinology, diabetes and metabolism in the UB medical school.

Administering the drugs takes planning and guesswork because eating, exercise, stress, illness and other factors affect blood sugar levels. That means those with diabetes need to predict related dips and spikes well in advance. Mealtimes generally are the most challenging because they can spark pronounced spikes.

The food hits you a lot faster than the insulin does, said Szczesek.

Fiasp changes the equation. The newer formulation of NovoLog includes niacinamide (vitamin B3) to boost the speed of absorption.

There still is a lag, but it's the best thing we have, said Dandona, whose clinic helped with adult trials several years ago and who has prescribed the drug to some of his patients during the last two years, with good results.

Paige Szczesek, 6, of Cheektowaga, looks at her personal diabetes manager, which helps her and others more closely track her blood glucose levels and insulin use. (John Hickey/Buffalo News)

Paige and Tanner Szczesek are on the front end of the learning curve when it comes to keeping a proper balance. Their father, Shane, also was diagnosed as a child with Type 1 diabetes.

Greater speed is a godsend for the children, each of whom has a continuous glucose monitor and insulin pump to help control their blood sugar. Paige also has a personal diabetes manager, as part of her pump, that helps her family determine when she needs more insulin and how much. Sweet treats are always on hand for times when their blood sugar drops.

When she needs more fast-acting insulin, someone needs to decide when to administer it, then see how it's working. Ashley Szczesek uses a smartphone to keep tabs on blood glucose levels for both children. She teams up with Paiges school nurse and teachers to address shortfalls and spikes. There are phone calls or text messages every time blood sugar readings warrant, as well as reports about when and what the first-grader has eaten.

I can't just send my kid into school and say, I'll see you at the end of the day,' Ashley Szczesek said. I have an alarm set on my phone for when they're high or they're low. On top of that, especially during the night, I'll normally set several alarms to get up and check their blood sugars. If they're low, I go wake them up and give them something to bring up their blood sugar. If they're high enough, I give them some extra insulin. Between us as parents and the children, there's a lot of sleep loss."

Paige started using Fiasp last year after the clinical trial ended. Mastrandrea prescribed it off-label. Her brother started taking it a few weeks ago.

Paiges A1c level has dropped by 1 percent, to about 7 percent, higher than those without diabetes but in a good range for someone Paiges age with the condition.

Fiasp can ease the diabetes burden, but not erase it.

Those without adequate health insurance may be unable to cover higher co-pays or other out-of-pocket costs. Some people have not wanted to switch for that reason, Mastrandrea said.

Meanwhile, researchers continue to pursue a biologic cure, as well as an insulin pump that works with a continuous glucose monitor to deliver insulin on a minute-by-minute basis as needed.

In order to do that really well, Mastrandrea said, you want to have insulins that are faster-acting, absorb better and behave the way my pancreas does. Fiasp is in that category.

Some of Dandonas patients already have the most advanced insulin pump, the Medtronic 670G, though the device can be complicated for most adults to use, let alone children, he said, and still needs agents to more quickly bring blood sugars into the balanced range.

Still, for those in the field and for families like the Szczeseks, recent progress has been nothing short of remarkable.

Early prototypes of closed-looped models like the 670G once weighed two to three times that of adult patients, Dandona said, and now we have a tiny device doing the same thing.

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Breakthrough diabetes insulin drug developed with help from Buffalo - Buffalo News

Barbara Kay: Will 2020 will be the year of reason in the cancel-culture wars? – National Post

In the hard news business, it is well understood that if it bleeds, it leads. In cultural news, the same principle applies. Not a day goes by that we dont see a story of a panel discussion in jeopardy or cancelled, a controversial film withdrawn, or an academic on the incorrect side of a cultural debate de-platformed. One could be forgiven for assuming that cancel culture reigns supreme in the public forum.

Its gratifying, therefore, to report that a speaking engagement featuring a highly controversial researcher and clinician in the hot-button field of gender dysphoria will take place as planned at McGill University. The cancel-culture mould in this case was not broken by chance. A good strategic plan prevented a predictable brush fire of protest from becoming a conflagration.

Within the Department of Psychiatry at McGill University, the Division of Social and Transcultural Psychiatry (DSTP) pursues and promotes research, training and consultation in the domains of social and cultural psychiatry. Under the rubric of the Culture, Mind and Brain Program, an ongoing sub-division of the DSTP, with links to affiliated faculty in other McGill departments and worldwide, the DSTP is presenting a lecture, titled Children and Adolescents with Gender Dysphoria: Some contemporary research and clinical issues, to be delivered Jan. 23 by Dr. Ken Zucker, professor of psychiatry at the University of Toronto.

The cancel-culture mould in this case was not broken by chance

Dr. Zucker, a pioneer and leading expert in the field of gender dysphoria, is a cancel-culture veteran, and remains a magnet for trans activists ire. In 2015, when he headed up the Gender Identity Clinic at Torontos Centre for Addiction and Mental Health (CAMH), a post hed held for decades, he was targeted for condemnation by trans activists, who accused him of practicing conversion therapy, a false allegation that led to his summary dismissal. Dr. Zucker successfully refuted the charge in a later lawsuit against CAMH, resulting in a payout and retractions, but not in reinstatement. Dr. Zucker does in fact endorse supervised hormone therapy where warranted for adolescents on a case-by-case basis, but is a proponent of watchful waiting and for treating patients holistically.

DSTP Professor Samuel Veissire, organizer of this event, has been keeping me up to date on responses. To be honest, when I received his invitation to the talk and I saw Dr. Zuckers name, I entered it into my calendar with a question mark. I assumed the odds were high that he would be de-platformed by an administration browbeaten by activists. Im happy to be proven wrong.

Thats not to say there was no opposition. Queer McGill issued a warning on its Facebook page, repeating the canard about conversion therapy and advising friends that the talk would be given from a non-trans perspective. Prof. Veissire made a point of meeting with Queer McGill to hear their complaints and concern. Their position was basically no conversation without us at first, but he argued persuasively and respectfully that it is also reasonable for parents to assume their right and to honour their responsibility to be involved in decisions around radical physical changes in their children. This outreach in itself, letting people who object to the talk know that their perspectives are welcome in the conversation, I imagine went some distance in calming potentially roiled waters.

The Facebook pages comments were refreshingly diverse, and maturely considered. One queer woman of colour posted, I understand that this talk isnt for everyone, but I feel like we tend to be quick on condemning what we perceive like an attack, and police each other instead of practicing patience with different levels of understanding or even taking the opportunity to speak our truth.

Prof. Veissire also sent out a call for support on a sex research email list. Other scholars then shared it on Twitter. Responses were intended for both the administration at McGill and the public record, to show people or groups who had asked for the talk to be cancelled that there was widespread support for Dr. Zucker.

The Facebook page's comments were refreshingly diverse

Letters attesting to Dr. Zuckers eminence in his field flowed in from authoritative colleagues, such as Northwestern University psychology professor J. Michael Bailey, Columbia Universitys Developmental Psychoendocrinology Program director Heino F. L. Meyer-Bahlburg, University of Toronto psychiatry professor Ray Blanchard, and Harvard University psychology professor Steven Pinker.

Most touching was an ardent testimonial from Pique Resilience Project, a support group for detransitioned women. They wrote that they themselves would greatly have benefited from the more careful, evidence-based treatment approach that Dr. Zucker uses in his clinical practice. Their email concludes, Perspectives like Dr. Zuckers are critical to ensuring that more individuals dont make the mistake we did.

Most people, Prof. Veissire believes, want to see more brave conversations on difficult topics, but are reluctant to be publicly associated with politically unorthodox views. His private conversations with students have convinced him that when they see evidence that other people they trust are also open to these conversations, peoples fears ease up a bit.

Perhaps, as Prof. Veissire mused, 2020 will be the year of reason in the culture wars spin. Perhaps. Just minutes before filing this column, I was made aware that the Pride Therapy Network of Montreal had sent a letter dated Jan. 20 to Prof. Veissires asking that Dr. Zucker be de-platformed. And on Wednesday McGills Joint Board-Senate Subcommittee on Queer People also wrote the organizers to express disappointment and ask that the event be cancelled. It wont be. A more constructive approach would be for their members to attend the presentation and contribute their perspectives to the discussion in a civil fashion.

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Barbara Kay: Will 2020 will be the year of reason in the cancel-culture wars? - National Post

Former transgender patient will tell court that sex change clinic is putting children on ‘torturous’ path – The Telegraph

At a hearing in London on Wednesday, Mrs A's barrister, Jeremy Hyam QC, formally requested that Ms Bell, 23, be made a claimant in the case, and Mr Justice Supperstone, overseeing the case, agreed.

In a statement after the hearing, Ms Bell said: "I have become a claimant in this case because I do not believe that children and young people can consent to the use of powerful and experimental hormone drugs like I did.

"I believe that the current affirmative system put in place by the Tavistock is inadequate as it does not allow for exploration of these gender dysphoric feelings, nor does it seek to find the underlying causes of this condition.

"Hormone-changing drugs and surgery does not work for everyone and it certainly should not be offered to someone under the age of 18 when they are emotionally and mentally vulnerable.

"The treatment urgently needs to change so that it does not put young people, like me, on a torturous and unnecessary path that is permanent and life-changing."

At a hearing in London, Mrs A's barrister, Jeremy Hyam QC, said:"What is challenged is the current and continuing practice of the defendant ... to prescribe puberty-suppressing hormone blockers and then subsequently cross-sex hormones to children under the age of 18."

Former transgender patient will tell court that sex change clinic is putting children on 'torturous' path - The Telegraph

News Spread the love: Today is National Hugging Day! Cleveland Clinic 8:11 AM, Jan 21 – WXYZ

(WXYZ) Everyone needs a good hug every now and then.

And, according to Emily Mudd, Ph.D., of Cleveland Clinic Childrens, when we hug our children, it actually helps them regulate their emotions, and helps their brains develop.

We know that even from the moment were born, that touch, physical touch, attention, and hugs, are so very important for both nervous system regulation, and brain development, she said. From the moment were born we talk about kangaroo care and the importance of skin-to-skin contact and that really continues through childhood.

Dr. Mudd said research has shown that when we receive a hug, our brains release oxytocin which is the feel good brain chemical.

She said receiving a hug can also help children manage stress, by calming the release of cortisol which is the stress hormone.

When a child is having a meltdown or is overly stressed, Dr. Mudd said giving them a hug can help them calm down. When kids receive warmth and affection from their parents at a very young age, research has shown they are more likely to have greater resiliency, get better grades, and have better parent-child relationships into adulthood. But if your child isnt a hugger or gets shy around family members, Dr. Mudd said dont force them to give a hug.

Its okay to keep a very simple message, for whatever the age of the child is, that youre in control of your body, and if you dont want to hug an aunt or an uncle at this gathering, thats okay, but you can find another way to show them affection, she said. Instead, you can share a special memory with them, give them a high-five; spend extra time with them, and be sure to explain this in advance to your relatives too.

Dr. Mudd said, of course, hugs will change as your children get older, because teenagers dont have the same physical attention needs as toddlers.

But regardless of their age, letting your child know that you are there for them, unconditionally, is essential for their development and well-being.

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News Spread the love: Today is National Hugging Day! Cleveland Clinic 8:11 AM, Jan 21 - WXYZ

Hair VitaminsHow to Choose the Best Hair Vitamins and How Long Do You Have to Take Them? – Parade

Im stepping into 2020 with the healthiest hair Ive ever had, beauty influencer Brittanie Evans recently posted on Instagram, touting her partnership with SugarBearHair supplements. Celebrities like Kylie Jenner, Vanessa Hudgens and Gwyneth Paltrow have also credited hair vitamins for their luxurious locks.

But, do hair vitamins actually work? It depends, says New Orleans-based dermatologist Mary Lupo.

She compares hair supplements to chicken soupthey cant really hurt and may help. But, if you have a medical condition causing hair loss or other hair issues, hair vitamins likely wont help, and medical treatment may be needed.

What I think is important is that a person kind of go through a little checklist and make sure that before they spend money on vitamins, that theyve ruled out other things that can cause the problem, she says.

You may wish your hair was thicker or shinier or that it would grow longer more quickly. There are several reasons why your hair may not be cooperating.

Stress is a big one: Cortisol is your stress hormone, and a lot of women lose hair or shed hair, or their hair doesnt grow as long because of stress, Lupo says.

Stress can cause a condition called telogen effluvium, a scalp disorder that leads to hair shedding or thinning. It often occurs after instances of stress on the body, like surgery, illness or having a baby, Lupo says.

Other reasons you have issues with your hair:

Some conditions actually damage the hair follicle, Lupo says. Cicatricial alopecia, for example, is caused by scar tissue in the hair follicle, making hair fall out, and its usually irreversible. Alopecia areata is an autoimmune disease, causing quarter-sized chunks of hair to fall out.

Genetics also play a role in hair loss or conditions that cause it.

Hair loss because of chemotherapy could benefit from hair vitamins, Lupo says.

When you have hair loss from chemo, your hair has to cycle back and maybe the hair vitamins can speed it up a little bit, she says. I dont think its going to be anything earth-shattering, but I dont think it would hurt and it might help a little bit.

Related: Everything You Need to Know About Hair Extensions

For someone without a medical condition, vitamins could improve hair, but it will take time, six months or more to see a result, Lupo says. Thats because hair follicles grow in cycles.

According to the Cleveland Clinic, the anagen, or growing, phase, may last two to eight years, and refers to most of the hair you have. The catagen phase, which takes two to three weeks, refers to the timeframe when hair follicles shrink. The telogen, or resting, phase is when the hair falls out and can take two to four months.

If your hair cycles into the telogen phase too quickly, it may not grow as long as youd like, since once the hair sheds, and the process starts all over again, Lupo says. Seeing results from hair vitamins depends on taking them regularly for several months.

One month isnt going to make any difference at all, she says. Then, once you see the result, what I tell my patients is you can lower the dose of the vitamin. Like if it tells you to take four a day, you could cut it down to two a day or whatever as a maintenance dose after youve taken it for about a year. But, dont discontinue it or youll lose the benefit.

When shopping for hair vitamins, read the list of ingredients to ensure they contain substances that promote healthy hair: B vitamins, especially biotin, and vitamin E promote hair, nail and skin health, Lupo says.

The way vitamins help hair is really more from the antioxidant or anti-inflammatory (standpoint) to make the scalp healthier and the hair follicle healthier, she explains.

Many hair vitamins also contain plant-based ingredients, like ashwagandha and saw palmetto, which encourage hair health.

Ashwagandha has been shown to lower cortisol and also has anti-inflammatory properties, which promotes healthy hair. Saw palmetto is an ingredient in may products for men that helps with hair loss and prostate cancer.

Related: Is Hairprint the Secret to Covering Your Gray Naturally?

The U.S. Food and Drug Administration(FDA) does not review supplements, including hair vitamins, for safety before theyre allowed on the market. Lupo says hair vitamins are generally safe, though.

She suggests reviewing a hair vitamin products list of ingredients and choosing ones without too many additives. Also, look for ones that are Good Manufacturing Practice (GMP) certified, like the Natures Bounty brand.

Finally, be wary of any hair vitamins that make medical or any too-good-to-be-true claims.

I think that theyre safe for anybody, Lupo says. Its just the danger is if you have a medical condition that is undiagnosed and unrecognized that is causing you to lose your hair. If youre just taking vitamins, you might be wasting your time and your money, and youre not getting a proper diagnosis so that you can get appropriate treatment.

Along with hair vitamins, prescription drugs like Propecia and Rogaine can help treat hair loss, Lupo says, but women shouldnt take Propecia unless they are postmenopausal.

Dermatologists may also use platelet-rich plasma (PRP) therapy injections to trigger hair follicles to grow more hair. Lupo says usually four to six sessions of PRP are needed, and need to be repeated after several months to maintain results.

PRP is pretty much considered the gold standard of a therapeutic option, Lupo says. Its perfectly safe because you take your own blood, its spun down, you extract the platelets, and its injected into the scalp.

Diet also improves hair quality. Eating plenty of protein, omega-3 fatty acids, and fruits and vegetables, especially dark green veggies, can make your hair thicker and shinier.

If you have hair loss, thinning or other problems, Lupo suggests visiting your dermatologist to rule out any medical problems, even before trying hair vitamins or if youve tried hair vitamins with no results.

I would urge a person if theyve got a real hair loss problem to get the appropriate evaluation by a dermatologist and any recommended blood work that the dermatologist gives you sooner rather than later, she says.

Tempted to try a lash lift? Check out our guide.

Hair VitaminsHow to Choose the Best Hair Vitamins and How Long Do You Have to Take Them? - Parade

6 reasons dogs truly are mans best friend – Big Think

Under cover of darkness, a pack of ancient wolves slowly stalk the camps of our nomadic ancestors. But they are not on the prowl. These timid, congenial Canidaes have discovered they can scavenge human kills and midden piles for more reward, and far less risk, than the hunt.

Over successive generations, their offspring grow more docile and more dependent on their human benefactors. In time humans adopt these four-legged moochers, taking them into their service with the tacit agreement of better food and companionship. And so, the human-dog relationship was born.

That's one possibility at least. All that's generally agreed upon is that dogs became man's best friend as early as 15,000 years ago though some fossil evidence suggests domestication as far back as 30,000 years. As science writer James Gorman points out, this means we loved our tail-wagging besties before inventing agriculture, language, or permanent homes and even before we domesticated cows, goats, and, of course, cats.

"As we became friends with them, they became friends with us, and we have a dependency that's charming," Bill Nye, science guy and lover of all good dogs, told us in a 2015 interview. "It's enriched both the dog lives and the human lives."

For humans, the perks of the dog-human relationship run much deeper than games of fetch or a handy excuse to go for a nice, long walk.

Dogs see their people as family, and the feeling seems to be mutual.

(Photo: PxHere)

It's not our imaginations or a poetic attempt to explain behavior through personification. Dogs do view their people as family.

Cognition scientists at Emory University placed dogs in an MRI machine and scanned their brains while presenting them with different odors. Some aromas were of food. Others were from other dogs. And some were from the dogs' human companions. The dogs' brains' reward centers lit up most when presented with the human scents, showing they prioritized human relationships.

These results bolstered other research that shows dogs act similarly to human sounds and that they are the only non-primates to run toward humans for protection and comfort.

A little girl meets Lothair and Molly, two certified therapy dogs, at U.S. Air Force Base Hospital Langley.

(Photo: Brittany Paerschke-O'Brain/U.S. Air Force)

Dogs may be able to curb the risk of some mental diseases. That's the conclusion of research published in the peer-reviewed journal PLoS ONE, which found a link between dog ownership and a reduced risk of schizophrenia.

The researchers looked at 1,371 men and women across the socioeconomic spectrum. Roughly 400 participants suffered from schizophrenia, another 400 from bipolar disorder, and about 600 were controls. After a survey in which the participants were asked about pets, the researchers compared ownership with rates of mental illness.

They discovered that dog ownership before the age of 13 correlated with a 25 percent reduced risk of schizophrenia. Participants who owned dogs in the first years of life showed the largest protective effect.

"There are several plausible explanations for this possible 'protective' effect from contact with dogs," lead author Robert Yolken said in a statement. "Perhaps something in the canine microbiome that gets passed to humans and bolsters the immune system against or subdues a genetic predisposition to schizophrenia."

Sorry, ailurophiles. Cats did not show a similar link between ownership and a reduced risk of mental diseases.

Regular walks with your dog is great exercise and boosts cardiovascular health.

(Photo: PxHere)

The health benefits aren't just in the mind. Preliminary research published in Mayo Clinic Proceedings: Innovations, Quality & Outcomes suggests that pet ownership boosts heart health, especially if that pet is a dog.

Researchers evaluated roughly 1,800 participants using the American Heart Association's Life's Simple 7, seven life factors that people can improve to help achieve cardiovascular well-being. They then compared the health of pet owners with those who did not own pets and found a correlation between dog ownership and heart health. The researchers associated this salubrious effect with increased engagement and physical activity.

"In general, people who owned any pet were more likely to report more physical activity, better diet and blood sugar at an ideal level," Andrea Maugeri, a researcher with the International Clinical Research Center at St. Anne's University Hospital in Brno, said in a statement. "The greatest benefits from having a pet were for those who owned a dog, independent of their age, sex and education level."

Follow-up evaluations are scheduled until 2030.

An older gentleman sits with his canine companion.

(Photo: Pxfuel)

Better heart health means a better chance to live longer. That's according to a recent study and meta-analysis published in Circulation: Cardiovascular Quality and Outcomes.

The research found that dog owners who survived a heart attack were at a 33 percent reduced risk of early death compared to non-dog survivors. The same held true for stroke survivors (27 percent). Better still, dog ownership correlated with a 24 percent reduced risk of all-cause mortality, likely explained by an increase in physical activity and a decrease in depression and loneliness.

A study published in Scientific Reports corroborates a canine's life-giving, heart-healthy impact. The researchers reviewed the national registries for more than 3.4 million Swedes with no cardiovascular disease before 2001. Looking at the association between dog ownership and cardiovascular health, they found that single dog owners had a lowered risk of death, either due to cardiovascular disease (11 percent) or other causes (33 percent).

In a statement, lead junior author Mwenya Mubanga noted, "A very interesting finding in our study was that dog ownership was especially prominent as a protective factor in persons living alone, which is a group reported previously to be at higher risk of cardiovascular disease and death than those living in a multi-person household. Perhaps a dog may stand in as an important family member in the single households."

Put simply, dogs are better at ignoring bad advice than their human peers. Research out of Yale University's Canine Cognition Center tasked dogs with retrieving treats from a puzzle. The researchers presented the steps to solve the puzzle but included many extraneous steps in the demonstration. When it was the dogs' turn, they nimbly skipped the unnecessary steps, thereby showing their ability to filter information effectively.

How did human children perform? Not so great. The children settled on pure imitation, regardless of whether a step proved useful in solving the puzzle.

"This tells us something really important about how humans learn relative to other animals," Big Think author Arpan Bhattacharyya wrote on the study. "We're really trusting of the information that we get from other individuals even more trusting than dogs are.

"And what this means is we have to be really careful about the kinds of information we present ourselves with. We're not going to have the right filter for bad information, so we should stick to looking at information that's going to be positive, information that's going to be good."

Dogs really do resemble their owners.

(Photo: PxHere)

Dogs resemble their owners in more ways than floppy jowls or a perky gait. Dogs mirror their owners' personalities, and owners can use this information to better understand themselves.

Research published in the Journal of Research in Personality surveyed more than 1,600 dog owners, representing about 50 different breeds. They found that dog owners shaped their dogs' personalities. Extroverted owners rated their dogs as more active and playful, while the owners of more fearful dogs tended to exhibit more negative emotions. Similarly, more agreeable owners were guardians of less aggressive pets.

"We expected the dogs' personalities to be fairly stable because they don't have wild lifestyle changes humans do, but they actually change a lot. We uncovered similarities to their owners, the optimal time for training and even a time in their lives that they can get more aggressive toward other animals," lead author William Chopik said in a release.

Another study in Scientific Reports showed similar findings regarding stress. The researchers took hair and fur samples from owners and their dogs to measure both for the stress hormone cortisol. They found a correlation in long-term stress between the two.

These are six ways that science has discovered dogs aid their interspecies partner. As genetic research advances, dogs may prove they are man's best friends in unforeseen ways. Scientists studying the canine genome have found a number of canine disorders that closely resemble those found in humans, including some cancers. Further study may provide a wealth of information that could help us solve our own genetic mysteries.

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6 reasons dogs truly are mans best friend - Big Think

Doctors seek couples to test male birth control gel – and they’ll get paid 3,000 – Mirror Online

In news that will come as music to the ears of many women, scientists have developed a male birth control gel - and theyre looking for volunteers to test it out.

Researchers at the University of Kansas have developed the gel, and are seeking willing couples to try it.

The clear gel needs to be applied to the mans shoulders every day for two years, where its absorbed into the skin.

Couples will be paid $4,000 (3,063) in compensation to try it, although they must be willing to have a baby in case the gel fails.

The gel, called NES/T is expected to be more effective than condoms, but can cause a range of side effects, including acne and weight gain, according to the researchers.

It contains two hormones. The first hormone, progestin, naturally blocks the action of testosterone, keeping the testes from producing sperm.

Meanwhile, the second hormone, testosterone, ensures that the mans levels are normal, preventing side effects such as low sex drive, mod changes and erectile dysfunction.

According to the researchers, the gel is 90% effective - roughly 3% more reliable than condoms.

Thankfully, these effects are reversible within three to four months.

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For the trial, men will be paid $2,985 (2,286) to visit the clinic 31 times over two years, while their partner will receive $1,140 (873) for visiting 10 times.

Overall, the researchers are seeking 420 couples, including at centres in Edinburgh, Manchester, Los Angeles, Washington, Italy and Sweden.

Further details about the clinical trial can be found here .

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Doctors seek couples to test male birth control gel - and they'll get paid 3,000 - Mirror Online

Why Scottsdale, Arizona Is The Best Health & Wellness Destination To Relax And Recharge – Forbes

Sonora desert yoga.

A wellspring of wellness-based experiences await you in Scottsdale, Arizona. Certainly, it remains a mecca for PGA Golf tournaments and a boisterous hive for bachelor parties, but considering that wellness tourism is the fastest growing sector in travel, the region has seen a swift evolution in terms of integrating spiritual spa sanctuaries into overall experiential lifestyle stays that encompass a plethora of holistic modalities.

According to data from the Global Wellness Institute (GWI), wellness is an overall $4.2 trillion dollar industry which has seen 12 percent growth in the past 5 year with wellness tourism itself garnering $639 billion in sales. GWI Senior Researchers Katherine Johnston and Ophelia Yeung note that wellness tourism burst into the consumer consciousness just a few years ago, and its hard to grasp the speed of its growth and evolution. They add that hospitality and travel are converging, which sees the introduction of healthy hotels, wellness destinations, retreats and related tours going mainstream: this concept is transforming almost every facet of travel, and wellness tourism will only grow faster in the years ahead.

Meanwhile in Scottsdale, Dr. Meghana Thanki - proprietor of Second Nature Clinic, explains that the city was an early health and wellness adopter of due to its geography (being one with nature), golf + spa resorts, and overall open-minded sensibilities. What Im observing is that locals and visitors are seeking balance. Instead of attending an intense meditative retreat in a secluded location, people prefer to travel to a destination like Scottsdale - enjoy that decadent meal with wine on one day - then seek us out on another to learn about alternative healing and restorative treatments. I think we appeal to a diverse audience because Scottsdale offers this wonderful flexibility - our varying approaches and levels of holistic healing accomodate everyone from the curious to the critical.

With growing receptivity to Eastern and Western wellness philosophies, there is growing agency and programming initiatives being offered by niche and mainstream companies; and as a result, guests and locals can expect to have opportunities that combine classic vacations stays along with elements that benefit mental and spiritual health.

With that in mind, these are the best wellness-based discoveries in Scottsdale:

Spiritual Adventure

REI Co-op Experiences

REI Co-op offers Scottsdale guides tours that include hiking, kayaking, camping, and more.

The easiest way to recharge, connect with yourself, and get a digital detox is to immerse yourself in the natural beauty of the Sonoran Desert. Through REI Co-op, their guided hikes allow you to appreciate the serenity of the region and the glory of its verdant cacti-riddled landscape. You first meet at the McDowell Sonoran Preserve Gateway Trailhead and meander through 3 miles of sandy trails via Browns Ranch to reach the mountain summit. On your journey, your expert guide teaches you about the local flora, fauna, geology and history of the region. Marc Berejka, president of the REI Foundation adds that we aim to shine a light on the symbiotic relationship between health and nature. Nature is good for us, so we must be good to nature, and time outside should be part of every doctors toolkit. At the summit, there is an opportunity to sit, pause and soak up the calming beauty of the area all to yourself.

Rest & Relax

Four Seasons Scottsdale Resort & Spa

Patio with views of Pinnacle Peak at Four Seasons Resort Scottsdale at Troon North.

Hugged by Pinnacle Peak and the Tonto National Forest, the hotel is a mountainous retreat located approximately 30 minutes north of downtown Scottsdale. For the last 20 years, its been the heart of the Sonoran Desert offering guests watercolor vistas and saguaro cacti-enriched landscapes. Along with its spacious 210 casita-style rooms and 22 suites, their spa and fitness programming is a leader in the region. Spa Director Lia Rowland encourages the fusion of fitness and mindfulness. This is best exemplified in their integrative programming, with the following highlights:

Zen Hike: Guests are encouraged to stop, breathe and take in the beauty of nature as they enjoy a guided hike that starts on property and meanders up to Pinnacle Peak. With a duration of about 90 minutes, the trail hike incorporates yoga poses at numerous pit stops on your journey to the summit. With an emphasis on being present in the moment, this is a unique way to invigorate body and mind.

Guided Meditation: Ideal for those who are curious about meditation but dont know how to begin. Participants are given direction and guidance via use of mental imagery, breathing exercises and focusing/channelling of energy - with the desired outcome to attain a state of relaxation for both the mind and the body via the learned skills and cultivation of becoming focused and present in ones state.

Aroma Design Experience: An Alchemista provides guidance to the guest who selects and customizes their own personal essential oil blend to enhance their well-being. Everything from birthdate, biological cycle, mood, and intention are taken into consideration. Once the custom oil blend is added to the organic body butter, the experience is followed by a customized massage.

Tai-Chi: A new offering for the spa and an alternative way to incorporate exercise with present mindfulness. The instructor guides participants through a series of methodical, gentle and meditative movements that resemble that of dancing underwater or moving in slow motion.

Omni Scottsdale Resort & Spa at Montelucia

Joya Spa's Relaxation area at Omni Scottsdale Resort Montelucia.

The spanish-styled hotel is set against Camelback Mountain and conveniently located a 13-minute drive from Old Town Scottsdale and Downtown Scottsdale.

Their award-winning Joya Spa is modelled on the old-world traditions of bathhouse rituals and ceremonies inspired by Moroccan deserts and Andalusia in Southern Spain. The lavish 31,000 square-foot space features numerous intention areas, saunas/steam areas, and treatment rooms. Upon entering the spa, youre greeted by the Joy of Purification - which is a 55lb quartz crystal for which guests are asked to place their hands on and breathe in/exhale to expel negative energy and worries. There are also protective amulets called the Hand of Fatima that are hung outside treatments rooms to bless and empower guests.

Services and treatments are extensive and Joya Spa offers everything from massage and facials; wellness and meditation; and naturopathic services. Highlights include the following:

Neuromuscular Massage: Ideal for those who sit for extended periods of time, such as at the office. Targeting specific areas, the massage is designed to release postural contractions and alleviate soft tissue distress.

Cranial Sacral Massage: A holistic practice which targets the central nervous system. Intuitive pressure is used to provide balance and alignment in mind, body and spirit.

Stress Management Meditation: A useful and practical session that allows you to recognize triggers and stressors. From there, skills and tools are provided to help you focus, achieve balance, reduce tension, release stress, and improve overall well-being.

Holistic Healing and Self-Care

Second Nature Clinic

Second Nature Clinic offers a vast range of services and treatments that include Ayurvedic Medicine, ... [+] Vitamin Shots, IV Drip Therapy, Massages and Aesthetics.

Dr. Meghana Thanki, owner of Second Nature Clinic in Old Town Scottsdale offers Naturopathic and Ayurvedic Medical therapies. She is a strong believer of introducing natural health/self-care into our lifestyle regularly until the point where it becomes second nature. Endeavoring to provide an accessible and comfortable environment, her Zen Lounge Experience is an ideal place to integrate these practices into ones life - such as her Healing and Happy Hour event. Every Thursdays between 5-7pm Dr. Thanki offers healing/restorative treatments for mind, body and soul at special prices that include 50% off vitamin shots, $20 off IV infusions, an aromatherapy bar, meditation workshops, and guest vendors.

The Phoenician Scottsdale

Gemstone healing facial is a 100% natural, vegan experience. Crystals and gem stones are placed on ... [+] and around the body for healing energy, bringing peace, clarity, and physical well-being.

After nearly 30 years of service, the new Phoenician Spa (replacing The Centre for Well-Being) completed its last phase of multi-million dollar renovation efforts in 2019. Now the 40,000 square-foot Phoenician Spa features a rooftop pool, 24 treatment rooms, salon services and an aroma design bar. Indulgent experiences are tailored to your level of comfort, from the more familiar facials and body polishes to modern fusions of Eastern Healing Philosophies such as their energy-transfer sessions (with the use of healing crystals); and Harmonic Bowl Healing, which uses sound energy that corresponds to one of the seven chakras to provide restoration, deep relaxation, or energy - all depending on the guests needs.

Movement Restoration

Floatation Therapy.

Opened in 2006 by certified massage therapist Trisha Haws and partner Brynn Martin, their companys philosophy is founded upon a massage therapy concept that emphasizes the restoration of natural movements via massage treatments - for instance, anything from soreness due to sitting at an office or recovery from that round of golf. Moreover, this popular space is where you can see everyone from fitness buffs to olympic competitors book a visit. The minimalist desert studio offers everything from traditional registered massage therapy, fascial stretching, cupping, to scrapping and floatation therapy via their 180 gallon saltwater float tank - which is said to take pressure off of the body for optimal relaxation and circulation. The magnesium in the epsom salts also boosts mental awareness, calmness, reduces inflammation, and alleviates sore joints and muscles.

We Do Men: The Man Spa

Client receives a facial treatment at We Do Men - A Male Concept Spa.

The wellness trend and respective surge in popularity can bring out staunch skeptics who are unsure of its effectiveness. But wellness doesnt necessarily mean you must dabble in astrological soul reading and energy therapy, rather, it also equates with self-care. For males, We Do Men is an ideal spot for wellness rookies to get their proverbial feet wet. Owner Stacey Grondahl, aka boss lady and manhandler - is all about creating a spa for men that addresses surrounding taboos and stereotypes about the industry, everything from skin care to grooming. She takes a humorous yet professionally direct no-B.S. approach to her respective services for guests. Along with educational one-on-one consultations and tailoring to lifestyle needs via what she describes as learning the way your male mind works, she even offers a booze, tunes and taboos menu - which involves using products with boozy elements in them (e.g. sake and blue agave tequila), as well as provide guests with local spirit samples (in a traditional beverage format).

Viticulture and Gastronomy

LDV Winery

LDV Winery is located in Old Town Scottsdale and features varietals grown from their own winery in ... [+] Southeastern Arizona.

Boasting vegan and natural wines, owners Curt Dunham and Peggy Fiandaca have been grape growing and winemaking over a decade. They champion the viticulture of Southeastern Arizona in each of their wine varietals. Due to the Chiricahua Mountains, theyre afforded a micro-climate of hot mornings and cool nights. As a result, the terroir and its temperature variances actually help intensify flavors and create vibrant acidity. Also, the integrity of wines are preserved as best as possible, so theres no tampering or manipulation done (e.g. no fining and filtration agents are used). Due to growing considerations for health and wellness, more people are exercising conscious consumption and LDV is able to appease to such needs of enjoying quality rather than quantity. If youre unfamiliar with their winery, an ideal starting point is to try their trio of award-winning estate grown Petite Sirah via their PS (Petite Sirah) I Love You package, which can be tasted at the wine bar or ordered online.

True Food Kitchen

Food philosophy of the restaurant is built about delicious dining and conscious nutrition. Pictured ... [+] here is their popular Edamame Guacamole dish.

A homegrown brand founded in 2008 that now boasts numerous locations, arguably their Scottsdale Quarter outpost remains one of the most popular spots. One of the founders, Dr. Andrew Weil explains that the restaurants mantra is simply that eating well is always in season. True Food emphasizes conscious nutrition that can be tasted in every one of the creations - without sacrificing flavor, creativity or indulgence. As much as possible, their dishes feature ingredients that are anti-inflammatory, boosts antioxidants, and immunity. Crowd favorites include their edamame guacamole, butternut squash pizza, and their unbeetable burger that uses beets, kuzu, jicama slaw, vegan mayonnaise, and crushed avocado.

Farm & Craft

Colorful, flavorful and healthy dishes whose food philosophy is featuring a "wellness menu".

Based in Scottsdale and founded by Riot Hospitality Group, Farm & Crafts seasonal wellness menu emphasizes four pillars to health in an overall welcoming and community-minded atmosphere: anti-inflammatory diet, increasing probiotic levels, maintaining high levels of antioxidants, and reducing overall stress. This is accomplished by offering guests sustainable, gluten-free, organic, and hormone-free ingredients in their dishes. Best of all, its flexitarian - whereby, you can opt for a strictly vegan and cleansing meal - such as their Chilled Raw Pad Thai; or something indulgent such as their Grass-Fed Steak Wrap. Beverages also cater to your needs and mood - where you can opt for an alcoholic cocktail thats served in a hollowed out watermelon, or something more holistically-minded such as their Carrot Cleanse juice (which is high in antioxidants, supports vision health, and offers anti-inflammatory properties with its mixture of carrot, orange, turmeric, lemon & ginger).

FnB Restaurant

FnB Scottsdale is owned by Pavle Milic and chef Charleen Badman. They feature uncomplicated seasonal ... [+] cooking and highlight an all-Arizona wine list, including their own vineyard creations from Los Milics Winery.

For an elevated dining experience, seek out this charming restaurant located in the historic Craftsman Court in downtown Scottsdale. Helmed by James Beard Foundations 2019 Best Chef: Southwests Charleen Badman, FnB boasts global flavors and seasonally changing menus. While she does offer traditional protein-enriched dishes (beef, poultry, fish, etc that are hormone-free, sustainable, and ethically raised), its actually her cruciferous creations that showcase her culinary prowess. In highlighting Arizona's bounty of local ingredients from nearby farming and agricultural communities, the veggie whisperer breathes life into otherwise humble ingredients - turnips are transformed with chimichurri; butternut squash is bolstered with sage, roasted garlic and pecorino; and spicy grilled broccoli (a crowd favorite) arrives to the table with the vibrancy of meyer lemon aioli and the salty crunch of pistachios.

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Why Scottsdale, Arizona Is The Best Health & Wellness Destination To Relax And Recharge - Forbes

Young women turning to egg donation for quick cash – Daily Nation

By ANGELA OKETCHMore by this Author

This is the in thing at universities. A quick way to make money. Egg donation among humans is a biological way to help women who cannot conceive naturally to have children.

However, for many young women in Kenya, the process has been turned into a quick way to earn money from clinics in Nairobi, which are themselves making a killing by selling them to the women who cannot conceive naturally.

Responding to adverts by these clinics on social media, hundreds of young women are giving away their eggs for just Sh50,000 to Sh70,000, oblivious of the risks they are exposing themselves to, and without knowledge of what these eggs fetch for the clinics.

Egg donation involves taking eggs from one woman, fertilising the viable ones, and then transferring them into the uterus of either the aspiring mother or a surrogate, in the hope of achieving pregnancy. This procedure is known as in-vitro fertilisation (IVF).

Last week, the La Femme Healthcare clinic, a fertility clinic along Ngong Road, Nairobi, placed an advert on its Facebook and Instagram pages seeking to recruit voluntary donors who would later be paid Sh50,000 should they turn out to be potential donors.

The voluntary donors were expected to be fit and healthy, 25 years old or younger.

At the end of the ad, the clinic placed Sh50,000 as monetary compensation to the donors. Visit us at the Green House Mall, Ngong Road, the advert states.

Dr Martha Kuruga, a fertility specialist at the facility, says several volunteers are required to match them to the women seeking eggs for IVF.

Interestingly, she says women seeking IVF using donor eggs have to part with Sh500,000. The amount includes the cost of the procedure and the treatment for the donor before the egg harvesting and afterwards should complications arise.

The Nation established that the cost could go as high as Sh1 million in other health facilities.

At the clinic, a donor is required to produce the National Identification card, school certificates and a photograph, for a start.

The information is then shared with women seeking donated eggs, who select a potential donor, based on physical appearance and academic qualifications.

Tests, including to check the blood group, are then conducted to match the donor to the recipient.

Once selected, the young woman is put on hormonal treatment to speed up the production of eggs in preparation for harvesting. Egg production depends on the individuals response to the hormonal treatment, and some women can produce as many as 40 eggs while some manage only five.

At the age of 23, Maria Nyokabi (not her real name) decided to sell her eggs without a second thought just because she needed the money.

Like many of her peers, she had on several occasions found herself broke. Being an orphan with no one to go to whenever she needed the money, she started a small business of packing and selling groundnuts at her campus room.

She would use the proceeds to pay rent and buy food but, with all these, she was still struggling.

So what do you do to realise your dream? How do you pay rent and how do you eat? Yet you have dangling cash at your disposal just to donate an egg?

The possible answer then was to sell my egg at Sh70,000. I was editing my college newspaper and would constantly see ads titled Donate Your Eggs At Sh70,000 and everyone was welcome if you met the criteria. I went for it, says Ms Nyokabi.

At first, she could not imagine that selling her eggs would be an option she would pursue. Fast forward, two years later she developed an interest.

A friend at the university directed her to a clinic where she had done it and was selected.

After tough scrutiny and answering a number of questions, she was chosen as a donor.

Weeks before the procedure, she wanted to give up but the Sh70,000 outweighed all her fears.

On her appointment day, she sat in the waiting room listening to music and reading a book.

After a few minutes, I received three taps on my shoulder asking me to proceed to the doctors office. We sat and looked over paperwork, blood was drawn, and then I went for an ultrasound to make sure everything looked fine. The doctor warned me that I might become overwhelmed with emotion during the process, she says.

No drinking, no sex, and no exercise until the end of the process, the nurse told me. She showed me how to administer the hormone shots myself, and off I went.

After four days, she had to return to the clinic to check her vitals and get an ultrasound check on how the eggs were multiplying. At the second day, she had a few noticeable symptoms of withdrawal other than boredom, her life revolved around the process.

Each day she went back to the clinic, she had three or four more follicle pouches filled with eggs popping up. Every day something new was happening in her body.

Two days before she was scheduled for the egg retrieval, she had more than 10 follicles in the ovaries, the nurse waved the cold metal rod up, down and around searching for more follicle pouches. The more follicles that appeared, the more uncomfortable she became.

Though painless and quick, the 45-minute procedure was life threatening, she says. She was weak and could not stand on her own. She was given antibiotics.

Third day after the surgery, she felt her body was rejecting everything she tried to put into it.

She had developed ovarian hyperstimulation syndrome and needed to have a procedure to drain all the excess fluid from her abdominal cavity.

She went back to the hospital and the fluid was drained; a suction cup was inserted into her vagina that sucked the liquid out.

I felt better and, from then, I swore never to do it again. I think my body can only survive one egg donation and I would never do it again because of money. That was physically painful, she says.

The same case applied to Monica Nyasukuta (not her real name). Last year, she had no one to turn to when she needed a bailout, fortunately, or unfortunately, when she sought help from her gynaecologist friend, she was advised to go and donate eggs.

Since she was clutching at straws, she had no option but to sign up to donate eggs. It was such a risky and top-secret experience that she only confided in her closest friend.

She doesnt like to talk about it, her friend recounts.

She had a series of tests to confirm her viability to donate eggs. She made the cut and the process began. It earned her Sh80,000 that temporarily put a smile on her face.

She signed a few legal documents that bound her never to go back to the clinic asking for her egg, and she left.

The hospital only keeps tabs when complications related to the procedure arise. If not, it lets go of the girl with it was nice doing business with you written on their faces.

Egg donors still take on medical risks: Women can suffer subsequent health problems, most commonly ovarian hyperstimulation syndrome (OHSS), in which the ovaries swell too much, causing fluid to leak into the abdomen and chest. This can be fatal, says Dr Paul Mitei, a gynaecologist and obstetrician.

Other symptoms include bloating, weight gain, nausea and, in rare severe cases, blood clots and kidney failure.

He says that before retrieval is done, a donor is first given an oral birth control pill for 21 days to stabilise the egg donors (ED) hormones and make it possible to time other medications. This causes breast tenderness, temporary weight gain, mood changes, missed periods and decreased libido.

She is then placed on steroids to suppress some hormones in donors with polycystic ovaries (PCO) for a week. Then they are later placed on follicle-stimulating hormones to stimulate and mature the eggs that will be donated. The hormones have serious side-effects to the young girls including headache, temporary weight gain, ovarian hyperstimulation syndrome (rare), multiple gestations (rare), ectopic (tubal) pregnancy (rare), ovarian twisting and injection site skin reactions. If done continuously, it might interfere with their fertility, he said

The donors are then given injections of gonadotrophin-releasing hormone antagonist to prevent premature release of hormones during the cycle; prevents ovarian hyperstimulation syndrome and human chorionic gonadotrophin, a trigger shot to (36-40 hours before retrieval) fully mature the eggs before they are retrieved

Finally, before retrieval, they are given two small injections of gonadotrophin-releasing hormone agonists to stop the production of some fertility hormones this allows the donor to donate a good number of high-quality eggs.

This is followed by antibiotics to decrease the risk of infection during egg retrieval.

Egg retrieval is always performed under ultrasound guidance. However, there is always a risk that a needle may puncture surrounding tissue or organs causing injury, bleeding and/or infection. Some of the hormones given to the young women are too strong for them and might [not] be necessary at their age, he said.

No one can say exactly what will happen if you donate your eggs because theres not much research into the long-term health risks egg donors may face, says Dr Diane Tober, who studied egg donors.

There have been reported cases of OHSS (which can be life-threatening), ovarian torsion, blood clots, development of long-term health problems, infertility and, according to some researchers, even cancer.

In October, arguing that egg donation carries the same risks as other surgical procedures involving anaesthesia, the San Francisco civil-rights lawyer MonaLisa Wallace petitioned the US Justice Department to crack down on the illegal egg-trafficking industry.

In a website of support and advocacy groups known as We Are Egg Donors, donors have found the donation process to be physically painful, emotionally jarring or both.

Some donors find the experience, which involves hormone injections for 10 days or more until a doctor pierces the vaginal wall with thick needles to suck out the extra eggs, produced differs greatly from the marketing.

There's a huge lack of data there to help women to make informed decisions. This is a big problem, simply because, people are making decisions that could affect their future health, well-being, and their ability to have children, Dr Tober said.

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Young women turning to egg donation for quick cash - Daily Nation

Teen detransitioners are telling their stories on YouTube – The Post Millennial

Authors note: I am grateful to the recently-launched caWsbar (Canadian Womens Sex-based Rights) for bringing the McLean Clinic, and its aggressive marketing techniques, to my attention, as well as for files they contributed to this column. Dr. Alicia Hendley, Phd in psychology and founding member of caWsbar told me: Were very alarmed about the current trend of young women having double mastectomies to treat their dysphoria.We urge medical professionals to move beyond the external pressures they are being faced with and to put into action their most sacred principlefirst do no harm.

The rapid escalation of gender-fluid identification amongst young people in the West is nothing short of astounding. Adolescent females are now in a majority of those seeking transition. An Ottawa clinic, CHEO, used to see one or two patients a year. Last year it saw 189. Its the same in other provinces:

Girls who are dissatisfied with their post-puberty bodies and wish to present as boys, naturally focus on their burgeoning breasts. They may use binders to flatten them, or they may seek surgical removal, referred to in the gender-fluidity world as top surgery.

Until fairly recently, a patient needed to undergo psychiatric testing before receiving OHIP approval for funding. Now a patient can be diagnosed by a GP or any other expert in gender health. Effectively, OHIP is now approving funding for any teenager who self-diagnoses as gender dysphoric, since Ontario law forbids any health professional from practicing conversion therapy. That is, any attempt by a doctor to inquire into contributing factors such as autism, anxiety, sexual preference, depression or other influencing factors could easily be construed as illegal.

The primary destination for top surgery in Ontario is the McLean Clinic, run by Dr. Hugh A. McLean, who has himself performed hundreds of top surgeries and who is not shy about promoting his clinic as a place where gender-fluidity dreams come true.

On the clinics Instagram page you can see dozens of photos of post-op FTM (female-to-male) clients posing bare-chested and happy. The clinic cheers on their patientsand prospective patientswith encouraging posts such as Postop one day! What a way to start the holiday season. Nice job, Dr. McLean! and Ready for a topless summer. Some of the females seem extremely young. Other adolescents comment, I cant wait to have this surgery too! Im jealous! In one photo, fellow surgeon Dr. Giancarlo McEvenue (more on him anon) wearing a mask and a Santa Claus hat holds up two buckets labelled Breast tissue, accompanied by a Dr McLean post: For all you good boys, Dr McEvenue is not bringing gifts, hes taking them away!

We already know that adolescence is a notoriously labile period in the maturation cycle, and that teenagers under the age of 18 (at a minimumour brains are not fully mature until 25) cannot be assumed to be making momentous decisions with truly informed consent. This Instagram page straddles a line between affirmation and recruitment.

Dr. McEvenue, Dr. McLeans (until recently) colleague at the McLean clinic (he is listed as a surgeon here now), is as well a paid consultant for Johnson & Johnson, whose products and services are employed in these surgeries. Under their sponsorship, Dr. McEvenue participated in a gender reassignment surgery panel last September in Markham, Ontario. You can watch the panel and his performance here.

In the video, you see a marked transformation in Dr. McEvenues pitch. Hes jettisoned the Instagram-friendly Santa hat and the buckets of breast tissue. He is now the smooth, Madman-esque embodiment of Corporate Guy, representing a mammoth company that brands itself as so LGBT-friendly they are bursting with Pride and self-congratulation.

Dr. McEvenue tells us that there could be as many as two million people with gender dysphoria in Canada about 1.5% of the population considerably more than the DSM-5s estimation of .002-.003%. Not only is the wish for top surgery not indicative of a disorder, he says, but it is even not a distress, and in fact it may not be necessarily exclusively related to gender dysphoria. Sometimes it is just breast dysphoria, he says, a term new to me, which turns out to mean that you dont like your breasts. If that is your issue, Dr. McEvenue is there for you, and will remove them. Because he has a passion for what he does.

At the 14:30 minute mark, Dr. McEvenue inadvertently demonstrates the health communitys general dumbing-down of the transition process that he is abetting.

He says, Believe it or not, when a patient wanted top surgery five or ten years ago, they had to go to a psychiatrist to get diagnosed. (Here he grins, presumably at the craziness of the very idea that a woman wanting to lop her breasts off might benefit from sorting through her motives with a mental health expert). He continues, If a woman comes to me for breast augmentation, I dont make her go to a psychiatrist. I say, okay, are you an adult? Do you understand the surgery? (laughter, applause. This audience really really wants to believe that top surgery on teenage girls is no big deal.)

So lets unpack these statements. Dr. McEvenue is comparing breast removal to breast augmentation as though they were two sides of the same coin. But theyre not. The parallel to a breast augmentation is a breast reduction. Both surgeries are performed on women who identify as women, but for reasons of comfort (reduction) or perceived enhanced sexual allure (augmentation), seek surgical alterations. Of course such women do not require psychiatric evaluations. How is augmentation in any way logically comparable to top surgery for transitioning girls who want their breasts removed so they can present as male? It isnt, unless you are attempting to trivialize both the operation and its psychological implications.

Furthermore, he asks his augmentation patients, are you an adult? But from the photos on the Instagram account, a great number of Dr. McEvenues patients are not adults at all. How does he know they truly understand what they are doing? Why wouldnt he want them to see a psychiatrist beforehand? If they are sure of what they are doing, what harm can deeper exploration do? And if they are not sure, whats the down side of them changing their mind? There is a long waiting list at the McLean Clinic, according to Dr. McEvenue. If one or two drop off it after consulting with a mental-health expert, wheres the tragedy there? Dr. McEvenue claims it is a matter of respect not to challenge his patients self-diagnosis. And at the 18-minute mark, he says, Why would I send [a patient] for a second opinion? Yet second opinions are standard in every other field of surgery, and no other surgeons consider them a sign of disrespect. (I guess its a good thing Dr. McEvenue isnt an oncologist.)

Dr. McEvenue enthuses about the benefits of Instagram (Instagram has been huge for us) and boasts of the clinics 14,000 followers. He claims that he doesnt moderate the discussion generated, although, If I see a negative comment, I delete it. The McLean Clinic is certainly dedicated to FTM transitioning as a fun experience.

Representing the patient experience on the panel is a likable transman, Yuri, who is warm, amiable and articulate, clearly at home in his new persona and eager to extol the benefits of his top surgery. Notably, he is now 30 years old, and had the surgery in his 20s. So he is hardly representative of the growing demographic that is seeking the surgery. If all the clinics patients were in their 20s, this panel wouldnt have been needed. The subject is only controversial because the age of those undergoing it is moving downward. Parents are of course concerned, confused and occasionally desperate for objective advice.

They wont find objectivity on this panel. Two of the speakers, the J & J host and Dr. McEvenue, are stakeholders in the business end of top surgeries. One of the panellists is a mature patient who had gone through years of reflection as an adult before doing it, and the last panellist, Melissa, is the parent of a child to whom she has given her full affirming support since her (then) daughter was four years old and refused to dress in princess clothes.

Melissa, unfortunately, plays the suicide card, saying, Id rather stand beside my son than over top of his grave. Suicide is a big possibility, Melissa says, and a parents job isnt to understand, its to support the dysphoric child. Dr. McEvenue reinforces her message with, a lot of time this is a life-saving operation. But since he is committed never to second-guessing the patients self-diagnosis, he cannot be sure that psychiatric help wouldnt be equally life-saving.

Brown University researcher Lisa Littman, who coined the term Rapid Onset Gender Dysphoria (ROGD) found that many adolescent girls with problems other than gender dysphoriaautism, anxiety, depressionglommed on to gender dysphoria as the source of their troubles through sites like Reddit and Tumblr, where social contagion took hold of them. These sites school new adherents in the kind of tropessuch as threatening suicidethat are sure to get their parents on board and assure instant affirmation from therapists. Parents should know this.

So just how real is the risk of suicide if a young girl does not get her double mastectomy? In a very recent article published in Quillette, psychoanalyst Marcus Evans, who formerly served as Consultant Psychotherapist and Associate Clinical Director of Adult and Adolescent Service at the Tavistock and Portman NHS Trust, the Tavistock Clinic being Englands premier public gender clinic, has this to say on the subject of suicide risk: Those who advocate an unquestioning affirmation-based approach to trans-identified children often will claim that any delay or hesitation in assisting a childs desired gender transition may cause irreparable psychological harm, and possibly even lead to suicide. They also typically will cite research purporting to prove that a child who transitions can expect higher levels of psychological health and life satisfaction. None of these claimsalignsubstantially with any robust data or studies in this area. Nor do they align with the cases I have encountered over decades as a psychotherapist.

What else is missing from this panel presentation? Questions that werent puffballs. For example, nobody asked whether Dr. McEvenue had ever had to reconstruct breasts after a client felt regret over the top surgery? (The McLean Clinic website says that very few trans folk regret their decision to undergo top surgery as part of their transition to their experienced gender, but they do not reference any studies.) Regretful detransitioners abound, and many of them want to be heard, but trans activists make life difficult for them when they speak out. Or another unasked question: Do you talk to these adolescent girls about their sexual preferences before planning their surgeries? Some girls presenting as trans are in fact merely lesbians who have difficulty processing that notion. In such cases, transitioning is neither required or advisable. But the subject did not arise on the panel.

As noted in a balanced, in-depth Atlantic magazine article on the subject by seasoned researcher Jesse Singal, the American Psychological Associations guidelines observe that adolescents can become intensely focused on their immediate desires. It goes on: This intense focus on immediate needs may create challenges in assuring that adolescents are cognitively and emotionally able to make life-altering decisions. The McLean Clinic is marketing itself to this demographic, and far from appearing to see challenge in this demographics vulnerability, they show every sign of seeing only market opportunity.

It will be clear to any objective observer that the McLean Clinics fun approach to top surgery and its dependence on social media promotes a perspective that underplays the complexity of the issue and overplays the magical-solution angle. The McLean Clinics bruited compassion for their patients is commendable. But their Instagram culture makes a mockery of the informed consent they claim to respect.

From a business perspective, the Mclean Clinics long waiting list is a sign of success. Their marketing techniques are not illegal. But are they ethical? That is a subject the Canadian Society of Plastic Surgeons might wish to take under deliberation.

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Teen detransitioners are telling their stories on YouTube - The Post Millennial

Exercise can help in the fight against cancer, but how do we persuade patients to do it? – The Globe and Mail

When a major new set of international guidelines on exercise and cancer was released in October, most of the headlines understandably focused on two key promises: That appropriate levels of physical activity could enhance quality and possibly length of life in those with a cancer diagnosis; and that they might help others avoid developing cancer in the first place.

The evidence for these two claims was dissected in depth in a pair of papers published simultaneously in Medicine & Science in Sports & Exercise, the fruits of a lengthy roundtable process involving more than three-dozen researchers from 17 health organizations around the world, including the Canadian Society for Exercise Physiology.

Less heralded, however, was a third paper from the same group that addressed a knottier problem thats all too familiar to exercise researchers: How do you move from knowing that something is a good practice to getting people to actually do it? Establishing a regular exercise habit can be challenging for just about anybody, but there are extra hurdles for people with cancer.

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Theyre all in different types of treatment, theyve had different surgeries, says Kristin Campbell, the director of the University of British Columbias Clinical Exercise Physiology Lab and one of the authors of the new guidelines. As a result, cancer survivors themselves have a lot of questions, like Is this safe for me?

The answer, in most cases, is yes but with some adjustments. While a previous set of guidelines published in 2010 had suggested that those undergoing cancer treatment should aim for the same amount of exercise as everyone else, meaning at least 150 minutes of moderate to vigorous exercise for each week, the new guidelines revise that target down to three weekly sessions of 30 minutes each.

That adjustment, based on a wealth of new evidence published in the past decade, is a good change, says Margie McNeely, the director of the University of Albertas Cancer Rehabilitation Clinic, and a more realistic standard for a survivor undergoing or in the early stages of recovering from cancer treatment.

For reasons that arent fully understood theories include reduced inflammation and oxidative stress, better blood-sugar control and changed hormone levels exercise has powerful effects on cancer cells.

Theres now strong evidence that regular physical activity lowers your risk of at least seven different types of cancer, and moderate evidence that it raises your chances of survival if you do get diagnosed. For those undergoing cancer treatment, it staves off reductions in physical function and helps reduce anxiety, depression and cancer-related fatigue.

In other words, the pressing question isnt whether cancer survivors should exercise its how to give them the confidence and information they need to do it.

Oncologists and oncology nurses are not trained in exercise, Campbell points out. They dont really know how to screen people or what to prescribe for exercise, because its just not their wheelhouse.

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In the third roundtable paper, Campbell and her colleagues propose a three-step process for oncologists: Assess, advise and refer. Simply asking about a patients current exercise capacity assessing is a good way to raise awareness, and basic advice about the new exercise guidelines advising may be enough to send some people down the right path.

But many will need a referral for more detailed help from an exercise specialist. Thats where initiatives such as the Alberta Cancer Exercise program, a continuing study led by McNeely, come in. Over the last year, more than 1,500 people with cancer have taken part in the supervised 12-week program at sites across the province.

About a quarter of the participants have what McNeely calls chronic cancer. Theyre not cured, but are living with the disease and will likely live for a long time while cycling in and out of treatment. Prescribing exercise for these people is trickier, but the benefits quality of life, physical function and the fitness to withstand their treatments are even more significant.

Given these constraints, there will never be a single set of generic exercise guidelines that applies to all cancer survivors. But the most essential message, now backed by solid science, is the simplest: Avoid inactivity, Campbell urges. Get out there and start doing whatever youre able to do.

Alex Hutchinson is the author of Endure: Mind, Body, and the Curiously Elastic Limits of Human Performance. Follow him on Twitter @sweatscience.

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Exercise can help in the fight against cancer, but how do we persuade patients to do it? - The Globe and Mail

Hormone Replacement Therapy Market Analysis, Scope, Future Trends and Opportunities During 2019-2025 – Fusion Science Academy

Microcrystalline Cellulose (MCC) Market Insights 2018, is a professional and in-depth study on the current state of the global Microcrystalline Cellulose (MCC) industry with a focus on the Global market. The report provides key statistics on the market status of the Microcrystalline Cellulose (MCC) manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry. Overall, the report provides an in-depth insight of 2018-2025 global Microcrystalline Cellulose (MCC) market covering all important parameters.

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The key points of the Microcrystalline Cellulose (MCC) Market report:

The report provides a basic overview of the Microcrystalline Cellulose (MCC) industry including its definition, applications and manufacturing technology.

The report explores the international and Chinese major industry players in detail. In this part, the report presents the company profile, product specifications, capacity, production value, and 2018-2025 market shares for each company.

Through the statistical analysis, the report depicts the global total market of Microcrystalline Cellulose (MCC) industry including capacity, production, production value, cost/profit, supply/demand and Chinese import/export.

The total market is further divided by company, by country, and by application/type for the competitive landscape analysis.

The report then estimates 2018-2025 market development trends of Microcrystalline Cellulose (MCC) industry. Analysis of upstream raw materials, downstream demand, and current market dynamics is also carried out.

The report makes some important proposals for a new project of Microcrystalline Cellulose (MCC) Industry before evaluating its feasibility.

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There are 3 key segments covered in this report: competitor segment, product type segment, end use/application segment.

For competitor segment, the report includes global key players of Microcrystalline Cellulose (MCC) are included:

competitive landscape in the market. The study encompasses market attractiveness analysis, wherein end-users are benchmarked based on their market size, growth rate and general attractiveness.

The study provides a decisive view on the global microcrystalline cellulose market by segmenting it in terms of end-users. End-user segments have been analyzed based on present and future trends. Regional segmentation includes the current and forecast demand for North America, Europe, Asia Pacific and Rest of the World (RoW). The report also covers demand for individual end-user segments in all the regions.

The study includes profiles of major companies operating in the global microcrystalline cellulose market. Key players profiled in the report include Asahi Kasei Corporation, BLANVER FARMOQUMICA LTDA, FMC Corporation, DFE Pharma GmbH & Co. KG, J. RETTENMAIER & SHNE GmbH + Co KG, Libraw Pharma, JUKU ORCHEM PRIVATE LIMITED, Sigachi Industrial Pvt. Ltd., Avantor Performance Materials, Inc., MINGTAI CHEMICAL CO., LTD. and Accent Microcell Pvt. Ltd. Market players are profiled in terms of attributes such as company overview, financial overview, business strategies and recent developments.

The report provides the market size of MCC for 2013 and forecast for the next six years. The global market size of MCC is provided in terms of both volume as well as revenue. Market volume is defined in tons, while market revenue is in US$ thousand. Market numbers are estimated based on various key end-user segments of MCC. Market size and forecast for each major end-user is provided in terms of global and regional markets.

In order to compile the research report, we conducted in-depth interviews and discussions with a wide range of key industry participants and opinion leaders. Primary research represents the bulk of research efforts, supplemented by an extensive secondary research. We reviewed key players product literature, annual reports, press releases and relevant documents for competitive analysis and market understanding. Secondary research also includes a search of recent trade, technical writing, internet sources and statistical data from government websites, trade associations and agencies. This has proven to be the most reliable, effective and successful approach for obtaining precise market data, capturing industry participants insights and recognizing business opportunities.

Secondary research sources that are typically referred to include, but are not limited to company websites, annual reports, financial reports, broker reports, investor presentations, SEC filings, Plastemart magazine, TPE magazine, internal and external proprietary databases, and relevant patent and regulatory databases such as ICIS, Hoovers, Onesource, Factiva and Bloomberg, national government documents, statistical databases, trade journals, market reports, news articles, press releases and webcasts specific to companies operating in the market.

Primary research involves e-mail interactions, telephonic interviews and face-to-face interviews for each market, category, segment and sub-segment across geographies. We conduct primary interviews on an ongoing basis with industry participants and commentators in order to validate the data and analysis. Primary interviews provide firsthand information on market size, market trends, growth trends, competitive landscape and outlook, etc. These help validate and strengthen the secondary research findings. These also help develop the analysis teams expertise and market understanding.

The report segments the globalmicrocrystalline cellulose marketas:

Microcrystalline Cellulose Market: End-user Segment Analysis

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* Estimates 2018-2025 Microcrystalline Cellulose (MCC) market development trends with the recent trends and SWOT analysis

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* Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.

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Hormone Replacement Therapy Market Analysis, Scope, Future Trends and Opportunities During 2019-2025 - Fusion Science Academy

Health Department announces services for the week of Jan 20 – Galva News

The Fulton County Health Department has scheduled the following health clinics and services. Please call the number listed with each service for an appointment or more information.

CANTON The Fulton County Health Department has scheduled the following health clinics and services. Please call the number listed with each service for an appointment or more information.

All offices of the Fulton County Health Department will be closed Monday, Jan. 20, 2020 in observance of the Martin Luther King holiday.

Maternal child health: Health screenings, WIC nutrition education and supplemental food coupons for women, infants and children. To make an appointment or for more information call 647-1134 (ext. 254). For Astoria clinic appointments call 329-2922.

Canton - WIC Nutrition Education - Tuesday, Jan 21 - 8-4 - Appt needed

Astoria - Clinic, WIC Nutrition Educ. - Wednesday, Jan 22 - 9-3 - Appt needed

Canton - Clinic - Thursday, Jan 23 - 8-4 - Appt needed

Adult Health Immunizations: Various vaccines are available. There is a fee for immunization administration. Medicaid cards are accepted. To make an appointment or for more information call 647-1134 (ext. 254).

Other times available by special arrangement at Canton, Cuba and Astoria.

Blood Lead Screening: Blood lead screenings are available for children ages one to six years. A fee is based on income. To make an appointment or for more information call 647-1134 (ext. 254). For Astoria appointments call 329-2922.

Family Planning: Confidential family planning services are available by appointment at the Canton office for families and males of child-bearing age. Services provided include physical exams, pap smears, sexually transmitted disease testing, contraceptive methods, pregnancy testing, education and counseling. Services are available to individuals of all income levels. Fees are based on a sliding fee scale with services provided at no charge to many clients. Medicaid and many insurances are accepted. After hours appointments are available. To make an appointment or for more information call the 647-1134 (ext. 244). *Program funding includes a grant from the US DHHS Title X.

Pregnancy testing: Confidential urine pregnancy testing is available at the Canton and Astoria offices. This service is available to females of all income levels. A nominal fee is charged. No appointment is needed. A first morning urine specimen should be collected for optimal testing and brought to the health department. Services are provided on a walk-in basis on the following days each week:

Canton: Every Wednesday & Thursday, 8-3:30 (for more information call 647-1134 ext. 244)

Astoria: Every Wednesday, 9-2:30 (for more information call 329-2922)

Womens Health: A womens clinic for pap tests, clinical breast examinations and vaginal examinations is available by appointment. There is a nominal fee for this service. Medicaid cards are accepted. Financial assistance is available for a mammogram. Cardiovascular screenings may be available to age and income eligible women. To make an appointment or for more information call 647-1134 (ext. 244).

Mammograms: Age and income eligible women may receive mammograms at no charge. Speakers are available to provide information to clubs and organizations. For more information or to apply for financial assistance, call 647-1134 (ext. 254).

Mens Health: Prostate specific antigen (PSA) blood tests are available for men for a fee. To make an appointment or for more information call 647-1134 (ext. 224).

Sexually Transmitted Disease (STD) Clinic: Confidential STD and HIV testing services are available by appointment to males and females at the Canton office. Services include physical exams to identify STDs, a variety of STD testing, HIV testing, education, counseling, medications and condoms. There is a nominal fee for services. Services are available to individuals of all income levels. Medicaid cards are accepted. To make an appointment or for more information call 746-1134 (ext. 224).

HIV Testing and Counseling: Confidential HIV testing and counseling services are available by appointment through the sexually transmitted disease (STD) clinic at the Canton office. To make an appointment or for more information call 647-1134 (ext. 224).

Tuberculosis (TB) Testing: TB skin tests are available at no charge by appointment. To make an appointment or for more information call 647-1134 (ext. 254).

Blood Pressure Screenings: The Fulton County Health Department provides blood pressure screenings at no charge on a walk-in basis during the following times:

Astoria - Screening - Wednesday, Jan 22 - 9-12 - Walk in

Health Watch Wellness Program: The Health Watch Program provides low cost lab services. Through this program adults can obtain venous blood draws for a variety of blood tests. Blood tests offered without a doctors order Comprehensive Metabolic Panel (CMP), Complete Blood Count (CBC), Lipid Panel, Prostate Specific Antigen (PSA) test, Hepatitis C test, and Thyroid Stimulating Hormone (TSH). A wide variety of blood tests are also available with a doctors order. There is a charge at the time of service. To make an appointment or for more information call 647-1134 (ext. 254).

Dental Services: The Dental Center offers a variety of basic dental services to children and adults. An appointment is needed. Medicaid and Kid Care cards are accepted. To make an appointment or for more information call 647-1134 (ext. 292).

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Health Department announces services for the week of Jan 20 - Galva News

Cancer patient shows his appreciation for Mayo Clinic on a billboard thank-you card –

Paul Olson wants everyone to know that he's thankful that Mayo Clinic saved his life ... twice.

That's why he purchased a high-profile billboard on South Broadway proclaiming that "I Beat Cancer Twice!" in big gold letters and thanking his doctors Larson, Kwon and Beahrs.

Actually, it's the second such billboard he put up in Rochester. The first was in 1997, five years after his first bout with prostate cancer.

"I have a perfect life thanks to Mayo. I would have been dead before I turned 50," said the retired 75-year-old Olson. "I think doctors need to get feedback from their patients. ... Everybody hears the gripes. Nobody hears the applause."

His story started in 1992, when he was referred to Mayo Clinic at age 47 and doctors discovered an advanced case of prostate cancer.

"A diagnosis like that is like looking at the end of a gun barrel," said Olson. "But the first thing they give you at Mayo is hope."

A treatment of surgery, chemotherapy and hormone therapy took care of the cancer. Olson, who was president of the Grand Rapids, Minn.-based Blandin Foundation, got on with his life. That meant travelling with his wife, running marathons, playing golf and eventually retiring.

Then in 2017, he ended up back at Mayo Clinic.

"I knew I had something funny going on," Olson said.

A special medical scanner unique to Mayo Clinic that he calls "magical" detected six tumors growing throughout his body. The prostate cancer had returned 25 years later.

Once again, his doctors at Mayo Clinic treated the cancer until no trace of the cancer was detectable in 2018.

"I just wanted to thank my doctors and Mayo for their extraordinary assistance ... for saving my life... again," he said.

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Cancer patient shows his appreciation for Mayo Clinic on a billboard thank-you card -

We Are A Safe Space: Center In Beaver County Aiming To Help LGBTQ Community And Break Stigmas – CBS Pittsburgh

BEAVER COUNTY (KDKA) A new center in Beaver County is focusing on helping the LGBTQ community.

Central Outreach Wellness Center in Aliquippa provides care while trying to break the stigma surrounding HIV and sexually transmitted diseases.

The clinic which opened Dec. 16, 2019 is the first of its kind for people in Beaver County, and the third location of its kind in the Pittsburgh region.

Alex Tatangelo, a nurse practitioner for the center, said the new location is in an area that lacks LGBTQ services.

Theres a lot of fear in that community still and theres a lot of fear going into a doctor and talking about things that may be concerning to them, Tatangelo said.

The clinic has STD testing, Hepatitis C care and hormone replacement therapy.

For the LGBTQ community, we offer PrEP, which keeps you protected for acquiring HIV, Tatangelo said. We offer HIV care and primary care for individuals who are already HIV positive.

What makes this center even more unique is it shares office space with the LGBTQ agencies PRISM and Project HOPE.

We are a safe space for LGBTQ youth and their allies to come and be themselves, PRISM founder Jaci Palmer said.

Palmer said her goal is to make LGBTQ youth feel like they matter and cut down on teen suicide.

She says LGBTQ teens are five times more likely to commit suicide than their heterosexual friends.

And as for David Adkins, whos HIV positive and the founder of Project HOPE, his goal is to create awareness for people impacted by HIV and AIDs.

He does that through outreach, support groups and fundraisers.

Ive lost a lot of friends to HIV and AIDs, and why am I still here? Theres a reason Im here to do what I can do, Adkins said.

Central Outreach Wellness Center has offices in Allegheny and Washington counties.

The center accepts appointments and walk-ins.

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We Are A Safe Space: Center In Beaver County Aiming To Help LGBTQ Community And Break Stigmas - CBS Pittsburgh

‘Sex Education’ Primer: Where Things Left Off and What to Expect From Season 2 – Hollywood Reporter

The students of Moordale Secondary are growing up in season two of Netflixs breakout Sex Education.

When creator Laurie Nunn introduced her coming-of-age comedy about teenage nobody Otis Milburn (Asa Butterfield), who launches an underground sex clinic at his school, her characters inventive riffs on teen-com clichs that exist somewhere between the present and a nostalgic re-imagining of the John Hughes era were just beginning to awkwardly fumble their way through various sexual rites of passage.

The fumbling continues in season two, a way for Nunn to mine humor and relatability from this tale of a sensitive boy searching for his place (and libido) in the grand scheme of things. But theres a sureness of step now, for both Nunn and her colorful collection of misfits, who use the shows sophomore season to explore urges and fetishes and the kind of hormone-fueled existential crises grown-ups remember with detached amusement.

Season two of Sex Education delivers more heartfelt laughs and engaging storylines about a handful of fan-favorite characters, but it also pushes its storytelling, introducing new faces, confronting even more controversial issues, and asking viewers to grow with it. Before season two debuts Jan. 17, here is a refresher on the biggest storylines from season one and a look ahead at what to expect from the new episodes.

Old Dramas

The debut season ended with resolved conflicts and more than a few unanswered questions. After pining after school rebel Maeve Wiley (Emma Mackey) all season, Otis began a relationship with Ola (Patricia Allison), a fellow weirdo and the daughter of handyman Jakob (Mikael Persbrandt). Jakob and Otis mother, Jean Milburn (Gillian Anderson), were shacking up, but neither teenager knew thatyet. Just as Otis began to embrace his stunted sexual appetites, forgiving his mother for penning a book about his repressed urges and inability to pleasure himself, his romance with Ola kick-started his sex drive.

Meanwhile, Maeve, who spent much of season one struggling to survive on her own, was forced to say goodbye to her unreliable brother and her academic career after shouldering the blame for his illegal drug dealing at school. Eric (Ncuti Gatwa), who was tormented by school bully Adam (Connor Swindells) for much of the year, was left contemplating a confusing, violent hookup as Adams father, Mr. Groff (Alistair Petrie), sent him packing to military school.

Season two will check in on the status of Otis and Olas relationship and that of their parents as well as Erics romantic endeavors and Maeves life at the trailer park now that her business venture and friendship with Otis have been put on the back burner.

New Kids

With a new year comes new students, and a trio of characters make their mark early on in season two.

I still think that Otis very much leads us through the world, and he's still our protagonist, but I really wanted to be able to kind of get under the skin of some of our other characters, showrunner Nunn told The Hollywood Reporter about the shift in focus.

Expanding the world of Moordale means storylines focusing on fan favorites like Aimee (Aimee Lou Wood), Lily (Tanya Reynolds) and Jackson (Kedar Williams-Stirling). Newcomers include Rahim (Sami Outalbali), a French foreign exchange student who factors into Erics story in surprising ways; Viv (Chinenye Ezeudu), a brilliant young woman who shares a special bond with Jackson following a traumatic event; and Isaac (George Robinson), Maeves sarcastic new neighbor, who comes to her aid when her mother (Anne-Marie Duff), a former addict, pushes her way back into her daughters life.

In many ways, season two seems to bid farewell to childhood, untethering itself from former friendships and expected character arcs in favor of bolder storytelling. Otis seems content in his dalliance with Ola, and though he continues to dole out his brand of "sexpertise" to his fellow students, the days of bathroom confessionals are long gone. Eric, who went through an identity crisis in season one following a horrific assault, sports an enviable amount of self-confidence, even when lamenting his nonexistent love life. Maeve, whose cynicism masked her dreams and ambition, is forced to fight for what she wants for once.

The influx of new characters also means that Andersons soft-spoken sex therapist will take on a bigger role in season two, venturing from the safety of her home office and finding new clientele at Moordale Secondary after an episode of STI hysteria makes it painfully clear just how archaic the schools sex education curriculum is.

More Sex

Speaking of sex, theres certainly more of it, and in greater variety, in season two. Otis, who achieved the impossible by finally having an erection in the season one finale, is mastering the art of masturbation and learning how to please his girlfriend. Butterfield is given a big comedic moment in season two that involves a self-pleasuring montage set to the heavenly choir cover of the Divinyls' I Touch Myself that encapsulates everything this show does well before abruptly ending in the most nightmarish of ways.

This season also explores queer sex, using Eric and Rahims friendship to cover topics that feel taboo, even in these modern times, and forcing other mainstays to question their impulses in interesting, comical ways. There are fetishes and female orgasms galore, but there are also meditations on the aftermath of sexual assault, repressed desires and pregnancy scares.

Even More Questions

One thing Sex Education has also done well, and continues to shine at in season two, is letting its characters exist in a state of ambiguity. Yes, there are big payoffs, victories for underdogs, reconciliations for strained relationships, but Nunn poses as many questions as she answers by the time the eight episodes are over. Will Eric and Adam reunite? Will Maeve and Otis finally admit their feelings for one another? Will Jean write her book? Will Otis lose his virginity? Nothing is tied up too neatly this season, which might disappoint some, but its also proof that this series is fully dialed into the story its trying to tell, a messy, conversation-starting contemplation on the joys and pains of growing up thats as sincere as it is silly.

The second season of Sex Educationlaunches Jan. 17 on Netflix. Stay tuned to THR for additional coverage.

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'Sex Education' Primer: Where Things Left Off and What to Expect From Season 2 - Hollywood Reporter