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Archive for the ‘Hormone Physician’ Category

Dr. Gaines Provides Insight Into How People Can Best Protect Themselves and Their Families From the COVID-19 Virus – Yahoo Finance

Dr. Gaines of Life Gaines Medical & Aesthetics Center sends out info about the COVID-19 virus for concerned patients and the general public in South Florida

Boca Raton, Florida--(Newsfile Corp. - March 20, 2020) - LifeGaines reaches out to its patients and community who are concerned about COVID-19, the novel coronavirus.

"Dear LifeGaines Medical & Aesthetics Family,

"The staff at LifeGaines takes your health and safety seriously and we won't compromise when it comes to protecting our patients. We are closely monitoring the World Health Organization and CDC with regard to ongoing developments of the coronavirus (COVID-19) and we are committed to providing you a safe and clean environment.

"In an effort to reassure our patients, we want to inform you that we are continuing our rigorous routines to keep our practice sanitized and clean and will continue to take every precaution to keep you safe. Our daily safety standards include disinfecting our treatment rooms and equipment after each treatment and thoroughly washing our hands. We also wear new, clean gloves when applying products to our patients' skin and discard after each use. Also, our office is cleaned daily including wiping down tabletops, doorknobs, and equipment using medical-grade disinfectants."

Dr. LifeGaines reaches out to patients and community in light of COVID-19

To view an enhanced version of this graphic, please visit:https://media.zenfs.com/en-us/newsfile_64/2f7e8700c7c06672c2bf9192647742d9

Please don't hesitate to contact us with any questions or concerns at (561) 931-2430. We look forward to seeing you soon.

https://www.facebook.com/LifeGaines/posts/1067452740282001 - Dr. Gaines gives a message on Facebook about how he is boosting his immune system as the COVID-19 virus spreads across the U.S.

Dr. Gaines talks about the benefits of IV ozone therapy. In addition to immunotherapy which helps boost someone's immune system, one should also drink plenty of water and get enough rest.

Story continues

LifeGaines is mobile and visiting patients at their homes with the IV ozone therapy treatment. Inquire about this by calling LifeGaines.Learn about IV Vitamin Therapy here: https://lifegaines.com/wellness-therapies/iv-vitamin-therapy/

Don't hesitate to contact LifeGaines with any questions or concerns at (561) 931-2430.

About Dr. Gaines' LifeGaines team:

LifeGaines is one of the most highly respected age management medical teams anywhere. Age management medicine pioneer Dr. Richard Gaines has years of experience specializing in hormone replacement therapy, sexual wellness, platelet-rich plasma, stem cells, aesthetics, and advanced age management protocols.

About Dr. Gaines:

Dr. Richard Gaines graduated from Boston University School of Medicine in 1981. He completed his internship at Tufts University School of Medicine in 1981 and his residency at Harvard Medical School in 1985, where he was an anesthesiology fellow at Brigham and Women's Hospital. He served as a physician at Huntington General Hospital, as an anesthesiologist at Harvard Community Health Plan and at Sheridan Healthcorp. Dr. Gaines opened an age management and wellness practice after a 40-year career as a physician and health care executive. He has a Fellowship in Anti-Aging and Regenerative Medicine (FAARM) from the American Academy of Anti-Aging Medicine, he's board-certified from the American Board of Anti-Aging & Regenerative Medicine (ABAARM) and he's certified as a Functional Medicine Practitioner with advanced training at The Institute for Functional Medicine.

LifeGaines is responsible for this press release.

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/53638

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Dr. Gaines Provides Insight Into How People Can Best Protect Themselves and Their Families From the COVID-19 Virus - Yahoo Finance

Eric Gopel, MD, on Growth Hormone Therapy in Patients With IGF1R Mutation – MedPage Today

While patients who are born small for their gestational age (SGA) have shown improvement with recombinant human growth hormone (rhGH) therapy, not much research has been conducted on patients who have the IGF1R mutation.

That's why Eric Gpel, MD, and colleagues conducted a study of these patients, which has been published in the Journal of Clinical Endocrinology & Metabolism. They found that while IGF1R carriers did show a lower growth response, they did catch up with other SGA patients.

Dr. Gpel answered some of MedPage Today's questions about their research on hormone therapy for these patients.

Why did you decide to study growth hormone (GH) therapy response in IGF1R patients?

Gpel: Although IGF1R mutations were first described in SGA patients more than 15 years ago, studies examining patient characteristics and treatment options in a cohort are very rare. Most probably IGF1R patients have been treated with the diagnosis "small for gestational age without catch-up growth" for a long time, without knowing the molecular diagnosis, and while case descriptions provided first hints on therapeutic success, cohort analyses were lacking.

You found that IGF1R mutation carriers showed a more pronounced growth retardation and lower response to rhGH therapy than others and that IGF1R mutation good responders showed catch-up growth to the levels of SGA patients. Were these results surprising to you?

Gpel: The clinical experience of our pediatric endocrinologists and various case reports gave the impression of a poorer therapeutic outcome compared to SGA patients. In addition, a lower response to GH could be expected due to the fact that the (aberrant) IGF1 receptor is at the lower end of the growth hormone axis. However, we were surprised by the high variability among patients; the more as we could not find any significant correlation with the kind of mutation. However, growth is a multifactorial process and other, genetic or non-genetic factors, can be expected to modify the response to GH.

What would you say to a physician who finds these results discouraging when it comes to treating patients with the IGF1R mutation?

Gpel: The decision in favor of a GH therapy should, of course, not be taken lightly. However, our study showed that -- despite a somewhat poorer average response -- some patients in the group of IGF1R mutation carriers clearly can benefit from GH therapy. Currently, it is simply not predictable how well or poorly a specific patient will respond to GH therapy. For this reason, we recommend favoring a treatment, re-evaluating the success of therapy periodically, and considering discontinuation of treatment in case of a poor response.

What would you like to see happen as a result of your study? More research? Clinical practice changes?

Gpel: IGF1R deficiency is a relatively rare finding and our study cohort is comparably small. Therefore, further studies are needed to identify factors that make GH treatment success in individual patients more predictable. This will make therapy decisions easier for pediatricians and parents. A distant aim would be to provide an estimation of therapy success according to the patients' individual mutation based on large cohort studies.

You concluded that IGF1R mutation should not be excluded from rhGH treatment, but that a critical re-evaluation of success should be performed periodically. How often do you recommend re-evaluation? What are some key things clinicians should be looking for when they re-evaluate?

Gpel: We would suggest regular control intervals of about half a year with special attention to changes of growth rate. The increment of height velocity SDS values within the first year of treatment could provide initial information about responsiveness. Of course, other aspects such as therapy adherence, socio-psychological aspects, and potential side effects have to be taken into account since GH therapy is a long-lasting treatment.

Is there anything else physicians should know about IGF-1 serum levels?

Gpel: We think that therapy monitoring by IGF-1 serum levels is one of the most difficult aspects in the treatment of SGA patients with IGF1R defects. They tend to have elevated IGF-1 levels, especially under treatment with GH. Because we do not have long-time outcome data, it is difficult to advise which is the upper acceptable limit in a patient with IGF-1 resistance under GH treatment that is both safe and that provides the best therapeutic outcome. Therefore, we recommend following these patients closely and collecting data carefully.

You can read expert commentary about the clinical implications of this study here and review the abstract here.

Last Updated March 17, 2020

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Eric Gopel, MD, on Growth Hormone Therapy in Patients With IGF1R Mutation - MedPage Today

Identify the root of your symptoms using functional blood tests at RedRiver Health and Wellness – St George News

Stock image, St. George News

CONTRIBUTED CONTENT Have you seen your doctor because you suffer from fatigue, brain fog, hair loss, digestive issues, joint pain, or other symptoms, and you were told your blood test is normal? You may have even been given a prescription for antidepressants, because your tests dont seem to indicate you have a physical health problem.

You know something is wrong and that youre not supposed to feel this way, but what is the cause? At RedRiver Health and Wellness Center, we believe the reason your blood test didnt show anything wrong with you is because most doctors use lab ranges instead of functional ranges when evaluating the results.

A lab range identifies acute disorders and diseases, while a functional range uses parameters of optimal health and identifies problems that often can still be reversed. This allows you to do something about the problem before its too late.

For instance, using a functional range, you can identify hypothyroidism even though your primary thyroid marker is normal according to a lab range.

Address your health problem before its too late

In functional medicine, we identify and manage the root cause of symptoms instead of using drugs or surgery to stamp them out although medications or surgery may still be necessary in some cases. The most common analogy we use in functional medicine is that when the check engine light comes on, we look under the hood to diagnose the problem instead of turning off the engine light.

Functional blood test ranges, which outline the parameters of good health, are an important tool to help us with this.

What is the difference between functional ranges and lab ranges on a blood test?

For the most part, lab ranges are based on a bell-curve analysis of the people who had blood drawn at that lab over a certain period of time. Naturally, many of these people are getting their blood drawn because they have a health problem.As a result, lab ranges have broadened over the last 20-30 years as the health of the United States population has declined.

This means many people with health issues may be told nothing is wrong because their labs fit in with most people at that lab. If you want to evaluate your health in terms of what is optimal, then functional ranges are the way to go.

Looking for patterns on a functional blood test

With a functional blood test, we also look at patterns of markers instead of looking at each marker in isolation. This is based on understanding that various aspects of human physiology are interrelated and affect one another. Doing this allows us to see how different systems influence one another to cause a pattern of symptoms.

For instance, evaluating immune cells more broadly can give us clues as to whether inflammation is chronic or acute and whether it is caused by a virus, bacteria, allergies or parasites. Other patterns can help us spot fatty liver, leaky gut, different types of anemia or autoimmune disorders. This then helps us determine what types of testing are further needed.

Functional blood tests are more thorough

Functional medicine blood tests are also more comprehensive than a standard blood test.For example, a basic thyroid test from your doctor probably only looks at TSH, or thyroidstimulating hormone. However, because autoimmune Hashimotos, which attacks and destroys the thyroid gland, causes 90% of hypothyroid cases in the United States, we run autoimmunemarkers to screen for Hashimotos. We also look at other markers to see whether additional factors are contributing to your low thyroid symptoms.

Ask my office for more information regarding a functional blood test if you are struggling withchronic health symptoms that are sabotaging your quality of life.

Written by JOSH REDD, chiropractic physician atRedRiver Health and Wellness Center.

S P O N S O R E D C O N T E N T

About Dr. Josh Redd

Josh Redd, MS, DABFM, DAAIM, is a chiropractic physician and author of the Amazon bestselling book The Truth About Low Thyroid. Redd owns seven functional medicine clinics in the western United States and sees patients from across the country and around the world who are suffering from challenging autoimmune, endocrine and neurological disorders. He also teaches thousands of health care practitioners about functional medicine and immunology, thyroid health, neurology, lab testing and more.

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Identify the root of your symptoms using functional blood tests at RedRiver Health and Wellness - St George News

Use these items to appropriate hormone imbalance – Sahiwal Tv

Imbalance of hormones causes many issues. When any hormone current within the physique turns into kind of than the prescribed restrict, then illnesses begin to happen. It is essential for ladies and men to stay wholesome that the steadiness of hormones within the physique is maintained. Hormones have an effect on not solely the physique but additionally the mind and feelings.

AIIMS physician Anurag Shahi, related to http://www.myupchar.com, says that hormones are the chemical parts of the physique, which make many glands within the physique. These highly effective chemical compounds are unfold all through the physique together with blood and helps the tissues and inside organs of their work. When the steadiness of hormones turns into ineffective, a selected hormone both decreases or turns into an excessive amount of.

->This situation is named hormone imbalance or hormone imbalance.

Specific meals may help steadiness hormones. There is a risk of enchancment in total well being with out taking any drugs. Although everybody's physique reacts otherwise, these wholesome meals are possible to make sure a nutritious diet that helps the physique operate higher.

Flaxseed seedsLinseed seeds can have all types of advantages for hormones. Linseed seed is a superb supply of 'phytoestrogens' and it particularly incorporates a sort of phytoestrogen, which is named lignan. Lignans have each estrogenic and antiestrogenic results, and are identified to have protecting advantages towards particular kinds of most cancers. Linseed seeds are additionally a very good supply of omega-Three fatty acids, fiber and antioxidants.

The nutsNuts like almonds have an effect on the endocrine system, which can assist cut back levels of cholesterol. They may assist decrease insulin and steadiness blood sugar ranges.

Walnuts specifically include polyphenols, which might defend the guts by combating free radicals within the physique. This ingredient may include anti-inflammatory brokers and is wealthy in omega-3s, that are wonderful for mind well being.

PomegranateThis antioxidant-rich fruit could assist in blocking estrogen manufacturing within the physique. Pomegranate has the power to stop the kinds of breast most cancers that react to estrogen. Pomegranate incorporates a pure agent that may inhibit an enzyme within the physique of girls that converts estrone into estradiol. It is a robust estrogen that may play a task within the origin of hormonal most cancers.

turmericTurmeric is at all times often known as a very good methodology for the remedy of irritation, as its made from curcumin. Many therapeutic properties are present in turmeric. This conventional Indian spice has the power to scale back ache throughout arthritis. Curcumin, the lively ingredient of turmeric, can simulate estrogen exercise. This herb may help cut back the ache of durations.

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Use these items to appropriate hormone imbalance - Sahiwal Tv

Polygamy, abortion, affordable housing: What passed during Utah’s legislative session – Daily Herald

The Utah State Legislature passed 510 bills over this years 45-day general session, ranging from a bill to fund affordable housing projects to a law regulating the disposal of fetal remains.

While this is lower than the number of bills passed during last years session, 574, or the 2018 session, 533, Utahs lawmakers still considered hundreds of bills that will impact the lives of residents.

Here is a look at some of the bills that did, and didnt, make it through the 2020 legislative session:

Bills that passed

Polygamy decriminalization: Sen. Deidre Henderson, R-Spanish Fork, sponsored a bill this session to reclassify bigamy as an infraction instead of a third-degree felony. Henderson said polygamists in Utah are tired of being treated like second-class citizens and feel like Utah has legalized prejudice against them. S.B. 102 received overwhelming support from lawmakers, 19 of whom signed on as co-sponsors. Prosecutors and polygamists testified in legislative committees that decriminalizing bigamy would prevent abuse in polygamist communities and lead to social integration.

Affordable housing: A bill sponsored by Lehi Republican Sen. Jacob Anderegg asked the legislature for $35 million to fund the development of affordable housing and provide rental assistance to families who are at risk of becoming homeless. While S.B. 39s funding was cut to $10 million, it successfully made it through the House and Senate. Anderegg said the bill is the result of work by the states Commission on Housing Affordability and believes it will help low-income Utahns who are legitimately one life event away from being homeless. The $10 million will go into the states Olene Walker Housing Loan Fund and be used to fund housing for low and moderate-income residents.

Violence against Indigenous women task force: Rep. Angela Romero, D-Salt Lake City, introduced a bill to create a Murdered and Missing Indigenous Women and Girls Task Force to study violence experienced by Native American women. The task force would consist of members of the House and Senate, a representative of a Native American victim advocate organization, and the director of the Utah Division of Indian Affairs. Native American women experience domestic abuse, sexual assault and other forms of violence at rates higher than nearly any other group. The House and Senate both passed H.B. 116 unanimously.

Fetal remains disposal: Sen. Curt Bramble, R-Provo, sponsored a bill to require medical facilities to either cremate or bury the fetal remains of abortions or miscarriages, leaving the decision between the two forms of disposition up to the mother. Bramble said the bill gives women more choices and ensures that fetal remains are disposed of in a dignified way. Critics of the bill say women already have a choice over disposition options and that it unnecessarily interferes with the doctor-patient relationship. Lawmakers amended the bill to only focus on abortion, but that amendment was later abandoned.

Abortion prohibition: A bill sponsored by Sen. Dan McCay, R-Riverton, would ban abortions in Utah at any stage of gestation, although it wouldnt go into effect unless the United States Supreme Court overturned its 1973 Roe v. Wade ruling. S.B. 174 passed through both chambers and, if Roe v. Wade were overturned, would make it a second degree felony for a physician to perform an abortion in Utah, with exceptions made for cases of rape, incest, or if the life of the mother were in danger.

Mental health services: A bill sponsored by Rep. Steve Eliason, R-Sandy, will expand Utahs mobile crisis outreach teams and fund the development of a behavior health receiving center. The bill asks for $5.9 million in one-time funds and an additional $10.8 million in ongoing money. H.B. 32 passed through both chambers unanimously. Another bill of Eliasons, H.B. 35, would study the need for adult beds at the Utah State Hospital.

Prosecutor and jail data collection requirements: Provo Republican Rep. Marsha Judkins sponsored a bill that would up the reporting requirements for attorneys offices and county jails throughout the state. Specifically, H.B. 22 would require county jails to compile information on inmate gender, race and ethnicity and require prosecutors to report whether charges were brought or if a plea bargain was reached, among other data points. Judkins said the bill will help increase transparency in Utahs criminal justice system and give lawmakers a better understanding of how to address concerns.

Public education funding: Lawmakers passed a proposal to amend the Utah Constitution to expand how income tax dollars can be spent to allow spending on children and individuals with a disability. Additionally, they passed a bill sponsored by Rep. Robert Spendlove, R-Sandy, to provide growth and stabilization in public education funding.

Pornography labeling: A bill introduced by Rep. Brady Brammer, R-Highland, would require all pornography in state to include a label warning about the harms porn can cause minors. The attorney general or any member of the public would be able to bring action against pornography manufacturers who failed to do so.

Bills that didnt pass

County government changes: Brammer also sponsored a bill this session that would require counties with populations greater than 500,000 to switch to either an executive-council form of government or council-manager form. The bill targeted Utah County, which will ask voters in November whether the county should switch from a three-member commission to a full-time mayor and part-time five-member council. H.B. 257 stalled in the House Political Subdivisions Committee on Feb. 12.

Clergy abuse reporting requirements: Rep. Romero also sponsored a bill this session that would remove child abuse reporting exemptions for clergy members and religious leaders. The bill received pushback from the Catholic League for Religious and Civil Rights, who argued that it would require priests to break the Seal of Confession. The bill was numbered but never made it to a House committee.

Hormone therapy for transgender minors: After abandoning legislation that would ban gender reassignment surgery and hormone therapy for transgender Utahns under the age of 18, Rep. Brad Daw, R-Orem, proposed a bill to study existing research on the health impacts of such practices. Daw said research that puberty blockers like Lupron have been shown to have negative side effects while LGBTQ+ activists said the bill targeted transgender youth. H.B. 449 failed in the House on a 17-55 vote.

Mandatory ultrasounds: West Jordan Republican Rep. Steve Christiansen sponsored a bill that would mandate that physicians performing abortions display fetal images of each unborn child to the mother and make each unborn childs heartbeat audible. All six of Utahs women senators, both Democrats and Republicans, walked off the Senate floor in protest of H.B. 364. While the bill originally passed both chambers, it was held in the House on the last day of the session.

Rent control: Rep. Jennifer Dailey-Provost, D-Salt Lake City, introduced a bill that would give cities and counties the authority to impose rent control measures within their jurisdiction. Currently, there is a state provision prohibiting municipalities from doing so. H.B. 131 was never heard in committee.

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Polygamy, abortion, affordable housing: What passed during Utah's legislative session - Daily Herald

Match Q&A: Will You Find What You’re Looking For? – AAFP News

Results of the National Resident Matching Program will be released on March 20. As Match Day drew near, Margaret Miller, student member of the AAFP Board of Directors and a fourth-year medical student at East Tennessee State University's Quillen College of Medicine, met with Kelly Thibert, D.O., M.P.H., resident member of the Board and a third-year resident at the Grant Family Medicine Residency at the OhioHealth Grant Medical Center, to discuss their respective Match experiences.

We're sharing their conversation below for the benefit of others awaiting Match results this week, as well as medical students who will participate in the process in the future. We also have been sharing other fourth-year students' answers to some of these same questions recently on Instagram.(www.instagram.com)

Kelly: Matching is a long process, and you're finally almost at the end. What has it been like for you?

Margaret: My experience is a little unique in that I am "couples matching." My husband is matching into internal medicine, so my experience is probably different than most applicants'. I did a few more interviews than a single applicant might, so that made my interview season longer.

I really didn't anticipate how exhausting the process would be! I like to think of myself as an outgoing person, but you meet a lot of new people and get fed a lot of information at each interview. It can be quite overwhelming sometimes to be traveling, to be away from your partner and trying to imagine yourself as a doctor in a new place you're not familiar with. I'm glad that's behind me. I'm anxious to find out where I'll be going.

What's the Match experience like from the other side, as a resident meeting candidates?

Kelly: The Match process from the resident side is actually really exciting and fun, which is a great change from going through the Match as a student. We get to participate in recruitment season, interview season and, of course, Match Day. Throughout the entire yearlong process of getting to know so many people -- who are potentially going to be part of your program -- you get inspired by all the passion they have and their excitement about becoming family doctors.

One of my favorite things about being a resident on Match Day is that we get to celebrate and welcome new people to our family. As residents, we spend many hours away from our families with this other family. These are people you want to know and love and like. It's exciting to see who is going to be part of your residency family. In my program, we have a Match Day celebration where we close the office during the second half of the day in anticipation of the release of names. This year, the celebration will look a bit different; more technology will be used than we typically would have, and we will not gather together in person to celebrate (social distancing), but we will unveil our newest 10 family members electronically and with no less excitement than any other year. We will then reach out to shower the newest residents with the "Grant Love" that our program is known for. It's really exciting from our end, which is a very different experience from the student perspective.

Margaret: My favorite interviews were definitely the ones where I had great conversations with faculty and residents who inspired me, and I was really excited by the opportunity that I might get to work with them as mentor or role model if I was a resident there. I would agree there are moments that can be really inspiring and invigorating for students as well, but it's still a lot!

What would you tell your pre-Match self if you could go back in time?

Kelly: Probably the biggest thing I would tell myself is just to chill out. I would say, "You have worked so hard to get where you are, from studying all the time to taking board exams and passing board exams. You've gotten to the point where you're about to become a physician. I know the Match is a huge thing and a huge step and it feels like you have no control over it. You have done marvelous things, and great things are coming your way. Things will work out as they will, and now it's out of your hands, so just chill out."

Margaret: I think that's the most difficult thing at this point. Things really are out of my hands. I don't have any control over the process from here on out. I've already sent my rank list and we're just in a waiting period, so good distractions are always welcome.

Kelly: What were you looking for in programs, and do you think you found it?

Margaret: I hope I found it. I definitely think I did at a handful of places.

There are a lot of things across the board that are pretty similar between programs because of certain core requirements that every program has to meet. For me, there were a few things that stood out to make a program different. One would be access to education and training opportunities in particular medical areas that I'm interested in, including hormone replacement therapy and caring for LGBTQ populations, and also a program that incorporated getting certification to do medication-assisted therapy. Other things I am interested in are advocacy and finding a place willing to let me continue working with the AAFP and other organizations.

Having a diverse group of residents was important to me -- people from different backgrounds from different parts of the country, people who look different from me and have different perspectives on medicine.

Lastly, the biggest thing that differentiates a program is the people you meet. I felt like I met more faculty than residents, so for me finding faculty I felt I could be close to, train under and learn a lot from was what I was looking for. I definitely think I found that. I hope I end up at one of those places where I felt like I found it.

Kelly: What are you excited or nervous about, knowing you're soon going to be a family physician?

Margaret: There are a lot of things I'm nervous about, but I'm actually more excited. I feel so ready to move on to the next part of my training.

I'm excited to have my own patients. As a student, you work so much as part of a team and introduce yourself as part of the team. It will be nice to see people over the course of my residency and help them deal with issues over time.

There are parts of medicine I'm nervous about, but the thing I really am hopeful about is that places I interviewed at -- and I would say this about almost all of them -- is that the support systems and faculty at each one really felt passionate about teaching, and that's why they were there. Maybe their particular emphasis of what they were interested in teaching wasn't what I was looking for, but they were still really supportive, kind people who were looking to train great residents, so I feel less nervous than I do excited. I'm more nervous about the Match than I am residency itself.

What have been the most meaningful moments of being a family physician for you?

Kelly: Being able to have my own patients and care for the whole family while practicing full-spectrum family medicine. People often say we are the cradle-to-grave specialty, and it's so true. We care for prenatal patients, deliver their babies and see them in the office with their families. They might bring Grandma in, too, because they liked the way you cared for them. Then you get to care for the whole family, even up through hospice and palliative care, which is a really important part of medicine.

We're so fortunate to be part of patients' lives. They allow us to be part of very intimate moments -- whether good or bad -- sometimes things they don't allow family members to be part of. These have been the most memorable things for me.

But also getting to know more about family medicine. You think you know about the specialty you are matching into, but you don't know the breadth and how incredible the specialty is until you're in it. You get to participate in things like the AAFP and get to know so many more people and the things they are doing in family medicine. I'm inspired daily by the family physicians I meet. I'm really happy I chose this profession and specialty.

Margaret: What's your advice for students transitioning to residency?

Kelly: Don't study. Take a break.

I had a different path to residency. I spent a year doing health policy between medical school and residency, so I felt like I had to study, and I did review some clinical stuff. Looking back, I don't know how much that helped me compared to the things I actually learned firsthand in the hospital. All the things you learned in medical school will help you, but nothing will give you what you need more than just being there and doing it as a resident.

You have worked so hard to get to this point. Take a break and celebrate the fact that you are about to become a family doctor.

So, what would you tell a first-year student already nervous about matching?

Margaret: The Match is definitely not something I worried about as a first-year, and I would not recommend worrying about it as first-year. Focus on the day-to-day of what you are doing. Nothing will prepare you more for your fourth year than first year, second year and third year, each in their time. You have enough on your plate to worry about first year!

As far as tips for nerves in general, try to balance your life the best you can. I think that's different for everyone in medical school. For me it was sometimes yoga or traveling, but it also was vegging out on the couch and watching Netflix after a big test. Getting involved in things that reminded me why I wanted to be a doctor in the first place was my saving grace.

What about your Match experience? When you were going through it, what affected where you applied and what were you looking for?

Kelly: I was all over the place because I was looking specifically for training. Location didn't matter so much because I thought whether I trained in a rural or suburban area, as long as I had the acuity and patient load, I would learn what I needed to learn and could go wherever I wanted, whether that be a rural or suburban setting.

Margaret: Family medicine is so different for different people. What kind of questions were you asking on the interview trail?

Kelly: It's funny because I was asking a lot of same questions you asked. I was looking for MAT training, gender-affirming care experiences, comprehensive reproductive health care, opportunities to participate in advocacy and social justice, and the ability to remain involved in the Academy. I think all those things are important.

Patients are so often marginalized and people might not have the bandwidth or knowledge set to provide these aspects of care. It's such a passion of mine. I wanted to be able to provide these things for patients no matter where I ended up.

I also was looking for places where I would be heavily trained in inpatient care and obstetrics. I feel wholeheartedly that it's important to be trained in inpatient and obstetric medicine as a family medicine doctor. We need to understand what has medically happened during a patient's admission because we then continue to manage the outcomes once they are discharged -- some of us even continue to care for patients in those inpatient and obstetric settings as family medicine doctors.

That's what's great about family medicine: We have such a breadth of practice that one can always find what they're looking for.

Margaret: Did you find all the things you were looking for?

Kelly: I 100% did, which is really incredible.

The rest is here:
Match Q&A: Will You Find What You're Looking For? - AAFP News

Angiotensin and the Coronavirus – Science Magazine

Theres quite a bit of confusion around the ACE proteins and coronavirus infection, and I can see why. The names in this area are pretty confusing, for one thing, and if youre not familiar with the tangled feedback loops that you get in human biology, it all starts to look like a tangle of wires pretty quickly. So lets have a look at the outlines of the system.

At right is a (pretty darn simplified) scheme. Angiotensinogen is a 452-amino-acid protein thats secreted by the liver (and has several functions all by itself). Its first ten amino acids are cleaved off by the enzyme renin to give you Angiotensin-I (also known as proangiotensin). That small peptide is then made even smaller by angiotensin-converting enzyme 1 (ACE-1), and interestingly, no ones ever found a function for angiotensin-1 other than to sit around and get cleaved in this way. This extra regulatory step has presumably come in handy over the eons.

ACE-1 takes off two more amino acids to give you the octapeptide known as angiotensin-II, and that one has profound effects on raising blood pressure (it has many other functions as well). It does this by binding to cell-surface proteins called angiotensin receptors (theres more than one type of these and they have a whole list of other downstream functions, but that takes us further afield). So you can see how an ACE-1 inhibitor could be good for high blood pressure, by blocking any formation of angiotensin II, and a renin inhibitor would be as well, by blocking the whole process a bit further upstream, and something that blocked that last binding step (an antagonist of the angiotensin receptor) would also probably work. All three of those are in fact classes of hypertension drugs the ACE-1 inhibitors came first (captopril in 1980, a famous triumph of 1970s med-chem and led to a whole slew of improved -opril drugs). The angiotensin receptor blockers came next (drugs with the -sartan suffix), and there are several of them. Renin inhibitors were far more painful to discover and develop, for a lot of reasons, and theres still only one on the market (from 2007).

Now to the coronavirus connection. Youll note that ACE-2 enzyme in the chart, and that one (formerly rather obscure) is having its moment in the the spotlight. Its expressed near the surface of various epithelial cells blood vessels, for sure, but also lung, intestine, and others. As shown, it is capable of clipping both angiotensin-I and angiotensin-II down further, to even small peptides (angiotensin 1-9 and 1-7) that have activities of their own. So it has its cardiovascular roles to play, but its become known for being a protein recognized by various coronaviruses to gain cell entry. There are others, naturally, and their relative importance can differ from virus to virus, but ACE-2 was shown to be important for the earlier SARS virus, and this current SARS-CoV-2 is quite similar. A cryo-EM structure of full-length ACE-2 with a coronovirus spike protein has recently appeared.

So something that binds to ACE2 and interferes with that viral hijacking would probably be quite interesting. Problem is, we dont have much of anything like that. ACE-1 inhibitors, as fate would have it, are not inhibitors of ACE-2 the enzymes are cousins, but not similar enough for the activity to cross over. Its not completely clear to me if a small molecule inhibitor in the active site would interfere with the viral interaction anyway, and it would be nice to have a few to see, but Im not aware of any such compounds. The confusion around the phrase angiotensin receptors has led to some people outside of the medical field wondering if the antagonist drugs (the sartans) would interfere with ACE-2, but that doesnt happen, either (theres another story with those, though see below).

A recent letter to The Lancet has noted that comorbidities reported so far for severe coronavirus patients include hypertension and either type I or type II diabetes. These patients are often being treated with ACE-1 inhibitors or angiotensin-receptor antagonists. The tricky part is that both diabetes itself and treatment with either of those drug classes increases the expression of ACE-2 protein. At first thought, that would probably not be a good thing, loading up the cells with more viral target proteins. But wait: theres another effect, as noted in this new paper. It builds on reports from China to suggest that a mechanism of lung injury during the viral infection may be through inappropriate effects of excess free angiotensin-II protein, which is floating around out there because the ACE-2 that would normally be soaking it up is occupied by coronavirus particles. If thats the problem, then increasing the amount of ACE-2 protein might paradoxically be just what you want to do to restore some balance to the angiotensin system. In that case administering more angiotensin receptor antagonists would be an effective way to upregulate the production of ACE-2.

There are a lot of such bounce-shot three-cushion mechanisms out there, so its not a crazy suggestion. That second paper proposes sorting through the existing patient data to see if there are correlations between severity of infection and angiotensin receptor antagonist therapy in particular, and I believe that this is ongoing. Epithelial cells are going to have ACE-2 protein on their surfaces no matter what, so the virus is going to be attacking those as a route of entry. If that second paper is right, then it could be that throwing more ACE-2 onto those membrane doesnt make the viral infection much worse, but does lessen the associated lung injury. If were going to have a lot more coronavirus patients, this would be a very good thing to know.

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Angiotensin and the Coronavirus - Science Magazine

Your circadian rhythm is the key to good sleep — here’s how to regulate it – CNET

Find out how to optimize your circadian rhythm so you can sleep better.

What do blue-light blocking glasses, sleep trackers, tech fasts and sleep supplements all have in common? Besides the fact that they are meant to help you sleep better, they all, in some way, attempt to help you regulate or optimize your circadian rhythm.

Read more:8 products to help you stop snoring

Your circadian rhythm is the internal "clock" that helps your body function, adapt and yes -- sleep. The two things that affect your circadian rhythm the most are environment and light, according to Dr. Craig Heller, Professor of Biology at Stanford where his research focuses on sleep and circadian rhythms. And while controlling your environment and light around you seems a bit difficult (read: impossible), there are definitely things you can do to reduce the risk that you are disrupting your circadian rhythm more than necessary.

To learn more about your circadian rhythm, how it works, and what you can do to optimize it so you will sleep better, keep reading.

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Your circadian rhythm is your internal clock that runs on a 24-hour cycle. This internal clock tells your body when you feel tired or awake throughout the day. You've probably noticed you have a pattern of when you feel the most awake or energized, and when you usually want to take a nap. The circadian rhythm is what drives that pattern, but not everyone has the same patterns.

Your body has an "internal clock "system known as the circadian rhythm.

"Circadian rhythms are internal cycles in many body systems and behavior that have a periodicity. Circadian systems enable the body to anticipate future events (e.g., food availability), coordinate body functions (e.g., sleep and hormone release), and optimize physiological processes with respect to each other," Heller says.

Since your circadian rhythm helps regulate many important processes in your body, it makes sense that disrupting it is bad news for your sleep, and therefore your health in general.

So what exactly disrupts your circadian rhythm the most? "Most commonly jet lag, shift work, bright light and especially blue light (computer and TV screens) when it should be dark," Heller says. Another big circadian rhythm disruption is when you transition to daylight saving time.

Signs that your circadian rhythm is disrupted include problems falling asleep, feeling energized or wired at unusual times, or feeling super tired for periods during the day. One thing that can help keep your circadian rhythm on track is trying to stick to a consistent sleep and wake-up time, which is not always easy.

Here are a few things to try if you think your circadian rhythm is off:

Keep a consistent sleep and wake up time: and try to keep it close to what feels natural to you (i.e., don't fight the fact that you are a night owl or morning person)

Get light in the morning: Get sunlight in your eyes first thing in the morning when you can. Getting light early in the day tells your body it's time to "wake up."

Avoid bright lights in the evening: Like Heller said, light can affect your circadian rhythm, which is why avoiding bright lights in the evening and dimming your lights can make a difference.

Avoid blue light at night: Turn off the TV and other devices that emit blue light at least three hours before bed. If you can't turn them off completely, install an app likeF.lux or wear blue light or amber-tinted glasses to block the light.

Traveling across time zones can disrupt your body's internal clock.

Sometimes your job or lifestyle forces you to do things you know aren't great for your sleep, but you want to make the best out of your situation regardless. Activities like working nights or traveling across time zones -- especially when the time difference is more than a few hours -- can really wreak havoc on your sleep.

"Presumably, you can't avoid travel across time zones or shift work, so you can learn the best ways to retrain rhythms by appropriate timing of light exposure and practice of good sleep hygiene," Heller says. "Apart from circadian considerations, there are many other things to do to improve sleep, most effectively through thermoregulation to support the temperature fluctuations of the body to maintain sleep continuity."

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The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

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Your circadian rhythm is the key to good sleep -- here's how to regulate it - CNET

RELIEF THERAPEUTICS HOLDING SA (SIX: RLF) Announces Plans to Test Aviptadil for the Treatment of COVID-induced Acute Respiratory Distress Syndrome…

GENEVA--(BUSINESS WIRE)--RELIEF THERAPEUTICS Holding SA (SIX-RLF, Relief or the Company) is initiating an urgent phase 2 clinical trial of RLF-100 (Aviptadil) in coordination with the Senior Leadership of the Government of Israel for the treatment of Acute Respiratory Distress Syndrome (ARDS) in patients with COVID-19 infection. The trial is being coordinated by Prof. Jonathan Javitt, MD, MPH, acting Chairman of the Scientific Advisory Board of Relief in coordination with Dr. Miki Halberthal, MD, CEO of the Rambam Healthcare Campus and Dr. Boaz Lev, head of Israels COVID task force and former Director General of Israels Ministry of Health.

RLF-100, acquired by Relief from Mondo Biotech, AG, has Investigational New Drug clearance from the US FDA and the European Medicines Agency for phase 2 trials in ARDS and has been awarded orphan drug designation by both agencies for treatment of ARDS, Acute Lung Injury, and Sarcoidosis. Aviptadil is Vasoactive Intestinal Polypeptide (VIP), a naturally-occurring peptide hormone that is known to be concentrated in the lungs. VIP has been shown in five species of animal models to have potent effect in models of ARDS and Acute Lung Injury. In these models, Aviptadil has shown potent anti-inflammatory and specifically anti-cytokine activity in the lungs.

The first clinical protocol will compare intravenous administration of Aviptadil to its administration via an endotracheal tube in patients who are already on mechanical ventilation because of ARDS. Assuming no new safety signals are detected, a second protocol will quickly be initiated to treat patients with early signs of respiratory distress in the hopes of preventing progression to ARDS and the need for mechanical ventilation.

After carefully reviewing the preclinical and clinical data, we believe that RLF-100 has a chance to be a safe and effective treatment for Acute Respiratory Distress Syndrome in patients infected by COVID-19, who otherwise have less than 50% chance of survival, despite intensive care. The State of Israel is eager to test this potentially lifesaving treatment in patients who today have no other therapeutic option, said Dr. Halberthal. We will try every possible mechanism to help safeguard our patients in this global crisis.

As a third-generation physician and the father of newly-trained physician, I am deeply honored to be working with longtime colleagues in Israels Ministry of Health on critical initiative. Owing to the rapidly expanding size of the epidemic and the extraordinary unmet medical need, we intend to initiate phase 2 clinical trials on an urgent schedule in order to bring a potentially life-saving drug to patients.

About RLF-100

RLF-100 (Aviptadil) is a patented formulation of Vasoactive Intestinal Polypeptide (VIP) that was originally developed and is currently marketed in Europe for the treatment of erectile dysfunction. VIP is known to be highly concentrated in the lung and to inhibit a variety of inflammatory cytokines. Aviptadil was awarded Orphan Drug Designation in 2001 by the US FDA for treatment of Acute Respiratory Distress Syndrome and in 2005 for treatment of Pulmonary Arterial Hypertension. Aviptadil was awarded Orphan Drug Designation by the European Medicines Agency in 2006 for the treatment of Acute Lung Injury and in 2007 for the treatment of Sarcoidosis. Both the US FDA and the EMEA have granted Investigational New Drug licenses for human phase 2 trials of Aviptadil.

About Acute Respiratory Distress Syndrome

Acute respiratory distress syndrome (ARDS) is a type of respiratory failure characterized by rapid onset of widespread inflammation in the lungs. Symptoms include shortness of breath, rapid breathing, and bluish skin coloration. Among those who survive, a decreased quality of life is relatively common.

Causes may include viral infection, sepsis, pancreatitis, trauma, pneumonia, and aspiration. The underlying mechanism involves diffuse injury to cells which form the barrier of the microscopic air sacs of the lungs, surfactant dysfunction, activation of the immune system, and dysfunction of the body's regulation of blood clotting. In effect, ARDS impairs the lungs' ability to exchange oxygen and carbon dioxide.

The primary treatment involves mechanical ventilation together with treatments directed at the underlying cause. The syndrome is associated with a death rate between 35 and 50%.

RELIEF THERAPEUTICS Holding SA is listed on the SIX Swiss Exchange under the symbol RLF. For further information, please visit the Relief website at http://www.relieftherapeutics.com or contact at contact@relieftherapeutics.com

Disclaimer: This communication expressly or implicitly contains certain forward-looking statements concerning RELIEF THERAPEUTICS Holding SA and its business. Such statements involve certain known and unknown risks, uncertainties and other factors, which could cause the actual results, financial condition, performance or achievements of RELIEF THERAPEUTICS Holding SA to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. RELIEF THERAPEUTICS Holding SA is providing this communication as of this date and does not undertake to update any forward-looking statements contained herein as a result of new information, future events or otherwise.

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Why Do Some People Eat When Stressed, While Others Stress-Starve – The Swaddle

Ah, stress. That inevitable, commonplace pandemic. Everyones stressed in the 21st century, and nobody seems to think it too much of a big deal, until that seemingly slight mental turbulence starts exerting a serious negative influence upon our health and daily functioning.

Stress is the bodys attempt to adapt to any unusual negative changes that it must face. For me, stress manifests in the way I eat. When Im stressed to a certain extent, I need copious amounts of chicken-cheese momos, or a batch of spicy fries. Then, as my stress progresses to something worse, I cant eat no matter how hard my gut groans for food. Why do I eat when Im stressed? And why cant I eat when I become more stressed?

Apparently, I am not unique. People tend to overeat when theyre stressed in order to distract themselves from whatever is on their minds. And people stop eating when theyre stressed because they simply cannot take their minds off whats stressing them, killing the need to do other things.

Related on The Swaddle:

Stress Is Contagious, but Heres How We Can Avoid Infecting Each Other

According to Harvard Health, feeling stressed makes our brain send cues to our bodies that it thinks might help us deal with the threat weve recognized. This is done via the stress hormone cortisol, which makes us crave food especially of the sugary, salty, fatty sort because it helps stock up on energy to fight whatever threat were dealing with. Increased stress also leads to a drop in metabolism, which can lead to rapid weight gain.

On the other hand, stress also stimulates the brain to secrete hormones like corticotropin-releasing factor (CRF), which activates the sympathetic nervous system that brings about the fight-or-flight response. Hormones like CRF are known to suppress appetite, decreasing how much or often we feel hungry, Dr. Kimbre Zahn, a family physician, told Shape. She adds, Individuals with persistent stress or those affected by generalized anxiety may be more likely to have chronic elevations of these hormones, resulting in prolonged appetite suppression. Often, stress can also lead to feeling nauseous, which also kills an individuals appetite. Losing ones appetite is particularly hard on the body, as increased cortisol leads to increased production of acid in the stomach. And if theres nothing but acid in the stomach, the organ will develop ulcers.

In any case, either eating too much or not eating at all, especially when stressed, are particularly bad habits, as they aid to the bodys struggle to cope. To avoid stress eating, take refuge in other comforting behaviors rather than eating junk food for example, eating healthy snacks and/or talking to a friend. As for a lack of appetite, what helps is to find foods that one can eat without feeling intense nausea. And drinking smoothies or milkshakes, which are easy to digest, will ensure the body has enough calories to keep it going through that turbulent period.

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Why Do Some People Eat When Stressed, While Others Stress-Starve - The Swaddle

Even among young men, healthier diet tied to higher sperm counts – Physician’s Weekly

By Lisa Rapaport

(Reuters Health) Young men who care about their sperm quality might want to lay off the cheeseburgers and fries, according to a new study that links a typical Western diet with a lower sperm count.

Men in the study who ate a mostly Western diet characterized by pizza, fries, sweets, sodas and red and processed meats typically had a lower sperm count by about 26 million than men who ate far less of these unhealthy foods. With a Western diet, men also had lower levels of reproductive hormones needed for optimal fertility.

Conversely, men with the healthiest eating habits with lots of fish, chicken, vegetables, fruits, and water typically had a sperm count 43 million higher than those who ate the lowest amounts of these foods.

Your sperm is what you eat, said coauthor Dr. Feiby Nassan of the Harvard T. H. Chan School of Public Health in Boston.

Diets rich in seafood, poultry, nuts, whole grains, fruits and vegetables provide antioxidants and omega-3 fatty acids that are essential for good sperm production, Nassan said by email.

Our results suggest the possibility of using dietary intervention as a possible approach to improve sperm quality of men in reproductive age, Nassan said.

A normal sperm count can range from 15 million to 200 million sperm per milliliter of semen.

Sperm quality and certain sex hormone levels have decreased substantially over the past few decades, driven in part by worsening diets in many parts of the world, the researchers note in JAMA Network Open.

The current analysis included 2,935 healthy men in Denmark, ages 19 or 20 on average. Researchers divided them according to how closely their diets matched four patterns: a Western diet; a healthy diet described as a prudent pattern of eating; a so-called open-sandwich diet consisting of whole grains and lots of cold cuts, fish, condiments, and dairy; and a vegetarian-like diet with lots of veggies, soy, milk, and eggs and little if any red meat or chicken.

Total sperm count with the Western diet was significantly lower than with any of the other three eating patterns.

The study wasnt designed to prove whether diet directly affects sperm or fertility. Researchers also focused on young, healthy men who might not yet be trying to conceive, and they didnt examine what happened in older men who wanted to become fathers.

Still, the study adds to evidence suggesting a healthy diet is good for mens reproductive health, Dr. Muhammad Imran Omar of the University of Aberdeen in the UK said by email.

And, men, like women, should try to adopt a healthy diet, cut back on alcohol and stop smoking months before they want to start trying for a baby.

However, men should be aware that it takes three months to produce sperm, said Allan Pacey, a researcher at the University of Sheffield in the UK who wasnt involved in the study.

If a man alters his diet on a Friday it wont improve his sperm by Monday, Pacey said by email.

SOURCE: https://bit.ly/2VQrYmr JAMA Network Open, online February 21, 2020.

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Even among young men, healthier diet tied to higher sperm counts - Physician's Weekly

How to Boost Your Immune System During the Coronavirus Outbreak – Entrepreneur

Simple methods to take care of your body and business.

Opinions expressed by Entrepreneur contributors are their own.

The following article is written by Ben Angel. Author of the book, Unstoppable: A 90-Day Plan to Biohack Your Mind and Body for Success. Buy it now from Amazon | Barnes & Noble | iBooks | IndieBound. And be sure to order The Unstoppable Journal, the only journal of its kind based on neuroscience, psychology and biohacking to help you reach your goals.

As we all grow accustomed to life in the age of novel coronavirus COVID-19, and scientists continue working on antivirals and vaccines,many experts are suggestingthe public take a holistic approach to general health maintenance. And as biohackers know better than most, positiveimmune responsecan beessential to staying healthy.While the following suggestionsare not ways to prevent you from contracting the virus, they areeasyways to keep yourself as healthy as possible.

As noted in a recent studyfrom the Sleep Foundation, "Without sufficient sleep, your body makes fewer cytokines, a type of protein that targets infection and inflammation, effectively creating an immune response. Cytokines are both produced and released during sleep, causing a double whammy if you skimp on shut-eye. Chronic sleep loss even makes the flu vaccine less effective by reducing your bodys ability to respond."

onsequently, the study advises taking two 30-minute-or-less daily napsto help mitigatesleep deprivation's effects on the immune system. But if you're having a difficult time getting to sleep, you can try the many binaural beats found on YouTube (Jody Hattons Power Napsis a good place to start)to help grab some winks on your coffee break.

Getting rid of sugar biohacks your immune system by removing a food source for the bad bacteria in your gut that can kill off your good bacteria. Autoimmune problems anddigestive issues are telltale signs of gut imbalance. Ideally, your gut should be 85 percentgood bacteria or probiotics.

You can check for gut dysbiosis through gut-microbiome tests from companies like Thryve Inside, as well as take stock of what youre eating on a daily basis. Fermented foods like sauerkraut, kombucha and kimchi can all help repopulate the good bacteria in your gutas well, leaving you with more energy and vitality.

Its been known for centuries that fasting has been used as a health protocol. Paracelsus, a great healer in the Western tradition, wrote 500 years ago that,Fasting is the greatest remedy, the physician within. In 2014, Dr. Valter Longo of the University of Southern California discovered that fasting for threedays (having nothing but water) could essentially reset the immune system. As summarized on Humann.com, holding off on eating for at least 16-18 hours after your last meal allowsyour bodys attention to become "focused on the current immune cells, recycling them and getting rid of the damaged cells. This means that during the fast, your body is running lean and mean with its white blood cells."

This practice, of course, should only be done if youre already healthy. But provided that's the case, who wouldnt want more time to completeprojects at workand get healthier at the same time?

Stress causes an inflammatory response within the body that can greatly affect your fight-or-flight response by releasing too much of the stress hormone cortisol. It also leaves us more vulnerable to infections and disease, both in and out of the office. That's why mindfully meditating has become a must forany biohacking entrepreneurs. There arevarious forms of mindfulness practices, ranging from the slow-moving poses ofyoga and tai chi to myriad breathing techniques. And arecentstudyinTranslational Psychiatry adds that "there seems to be something intrinsic about meditation itself that can shift gene expression and even boost mood over time."

Many airlines are now monitoring travelers's health before and after flights. According to the CDC, those with no respiratory symptoms do not need to wear a medical mask. The CDC also recommends the use of masks for people who have symptoms of the virus and for those caring for individuals who have symptoms, such as cough and fever.

In his book, Cockpit Confidential, author Patrick Smithstates that in an airplane, Between 94 and 99.9 percent of airborne microbes are captured, and theres a total changeover of air every two or three minutes far more frequently than occurs in offices, movie theatersor classrooms.

This is all the more reason why taking your vitamins during stressful times is important, since many of our essential minerals and vitamins can become depleted during stress. Vitamins C,B and D, as well as zinc,all support your immune system. Research shows that zinc alone can help keep inflammation at bay so that your immune response is better supported.

Related: Coronavirus and a Looming RecessionHow to Raise Capital in Uncertain Times

Although we are in uncertain times, we dont have to wait to see if we are healthy enough to overcome any type of sickness or disease. By implementing some of these holistic steps to boost your immune system, it will inevitably be a win-win situation for not only your health and well-being, but for keeping your business running like a well-oiled machine.Bottom line: Dont panic, and take advice from the medical professionals who are specialists in this area.

This article solely reflects the opinion of the author and is not intended as an alternative to recommended official government guidelines. For more updates and information about the novel coronavirus, visit the CDC's website.

Are you ready to become unstoppable?

Visit http://www.areyouunstoppable.com and take your FREE 60-second online quiz now. By answering a series of simple questions, my software will analyze your results and provide you with a comprehensive report that will indicate your identity type and lead you to the tools and tips you need to close that gap between who you are and who you could be. Take the quiz to get started!

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How to Boost Your Immune System During the Coronavirus Outbreak - Entrepreneur

When Dread Becomes You – Thrive Global

The Covid-19 crisis is triggering global fears that are beginning to cross over into panicky feelings (especially if you or a loved one is over 80 and in a nursing home). That state of mind is called dread.

In this piece I will endeavor describe and explain what is going on in your brain and mind when you are in a state of dread.

A disclaimer. It is empirically (i.e. observationally and experience) based and neither evidence nor research based. In fact, I would ask such researchers to weigh in and make what follows more scientifically sound.

Nevertheless, I hope it will help you better understand what is going on inside you and in so doing be calming, reassuring to you and even inform you and others who read this about what might psychologically stem the tide of rising fears.

When youre fearful, its because the way you have been living your life and the reassuring assumptions about the world that keep you calm enough to make good decisions are suddenly upended. Its as if the beliefs you have that help you to maintain your daily sanity and orientation are suddenly ripped away and the future you were living into, is suddenly extremely gone.

When thisoccurs a stress hormone called cortisol is released by your adrenal glands toalert your body to doing what it needs to do to survive. Added to that isanother hormone secreted by your adrenal glands called adrenaline whichdirectly gets your body physically ready to deal with stress which can comefrom either fear or excitement.

As your cortisol and adrenaline rise, so too does dread and a part of your brain which deals with emotions, also referred to as your mammalian/middle brain (more on that later), called your amygdala becomes highly activated.

Your amygdala is a combination emotional sentinel and point guard rolled into one. If your amygdala senses this is a time for survival it can hijack you away from accessing the prefrontal part of your cerebral cortex, that helps you assess as situation, consider options and then make rational decisions. The hijack actually coincides with more blood flow going into your middle and then lower/reptile brain to take action to survive and away from going to your upper/human brain where you can think and consider options.

When an amygdala hijack causes blood flow to go more to your middle and lower brains an interesting thing happens to something called your Triune Brain.

Paul MacLean was a physician and neuroscientist who first coined the phrase Triune Brain to go along with his theory that we have three brains: an upper/human/thinking brain, a middle/mammalian/emotional brain, and a lower/reptile/fight or flight brain. He postulated that they developed through evolution and have learned to align with each other when were functioning at our best. They are kept in alignment when they are all aimed a future that were living into.

However, when a relatively predictable future becomes completely uncertain and an amygdala hijack occurs with resultant blood flow change, your three brains can become decoupled with each brain functions separately from each other. We even have metaphors that reflect that: wigged out, unglued, out of sorts, out of you mind, freaked out, etc. When that happens, you have entered into a state of dread.

When that amygdala hijack occurs and each of the three brains fend for themselves, the upper/human/thinking brain can flip into obsessive thinking (thinking the same thoughts repetitively), the middle/mammalian/emotional brain can flip into high anxiety (with dread causing it to flirt with terror and then panicky feelings), and the lower/reptilian/fight-flight-freeze can flip into compulsive repetitive behaviors where you run, become angry or just freeze in your tracks.

When thisoccurs, you have what I refer to as Triunal Rigidity, where the three brainshave become rigidly connected to each other after the future they were aimingtowards gets stripped away. Triunal Rigidity is what makes your mind brittleand prone to feeling fragile as if it could break and shatter (= lose yourmind). It is that feeling of brittleness leading to fragility leading toshattering that can cause a sense of impending doom, terror and panic.

What is thesolution to this?

That is what Irefer to as Triunal Agility where whatever uncertainty and unpredictability isthrown at you, you can pivot, realign with what you need to do and then takeaction. And if that action is a littleoff, your Triunal Agility can enable you to re-pivot and realign some more.

What is necessary to transform your brittle Triunally Rigid mind that is consumed by dread into a rapidly adapting Triunally Agile mind that can reason?

Lets use theCoronavirus as an example.

It is the following information regarding Covid-19:

Generalized non-factually founded reassurances or worse, consistently inconsistent messages from President Trump who doesnt appear to grasp the situation or even understand the virus rather than being assuring actually appear to increase uncertainty and dread, because he makes it difficult to believe him.

The person best qualified to deliver the message must be highly trained, experienced in such matters, calm, clear, with specific directions and someone we can believe. Dr. Anthony Fauci who is head of the National Institute of Allergy and Infectious Diseases appears to be the current go to person to advise us.

See Glossary of terms above

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When Dread Becomes You - Thrive Global

Benefits and Risks of Using CBD Products | Your Life Arizona – AZFamily

CBD Cannabidiol (or cannabis)

Since CBD products hit the market, thousands of products hit the market, some good, some not good at all. If you are taking CBD, please check to see if your product meets label claims at CBDverify.com. To understand what they do when assaying products this is the assay of our 500 mg sleep CBD:

DESCRIPTION: PLANT HEALTH R.E.M. CBD

BOTTLE: 30 mil, 1 fl oz.

CBD CONTENT ON LABEL: 500 mg

RESULT: PASS

FINAL TEST RESULT

CBD TOTAL: 513.60 mg

CBG TOTAL: 3.04 mg

THC TOTAL: ZERO

Tetrahydrocannabinol (THC), the psychoactive part of the marijuana plant and it is in only one of our products, Pachamama, which comes from Colorado. It meets the federal regulations of the amount of THC allowed in a CBD product. For anyone who may be tested in the work force, I would not allow them to get this product.

We have within us an endocannabinoid system which is made up of two types of CBD receptors CBD 1 and CBD 2. CBD 1 receptors are highly concentrated in the brain and other parts of the body and CBD 2 receptors are in the immune system and in the periphery. There are studies on CBD for the treatment and prevention of cancer through the CBD 2 receptors, regulating immune function. Not only does the research show promise with CBD in cancer patients, it also can help with nausea that comes with cancer treatment and can improve appetite.

There is also research on Multiple Sclerosis and Alzheimers Disease showing that there are more CBD receptors than in patients without either condition. It is called a compensatory response, so that, if a person with these conditions takes CBD, there is a stronger cellular response to repair.

There are contraindications with using CBD listed below:

1. If you are on medications, CBD can compete for liver pathways, leading to higher levels of the medication in your system (consult your physician)

2. It can raise liver enzymes in certain individuals, not most though. I believe this to be in patients that take multiple medications, however it can also be from a CBD product that is not organic and has pesticides and other chemicals in it. The last thing we should do is take a product for our health that is not clean, otherwise we are poisoning ourselves.

In our clinic, I prescribe CBD mainly for sleep, anxiety and pain as when CBD locks into our receptors it induces rest and relaxation as well as acting as an anti-inflammatory agent. We only carry products that are clean, meet label claims and the ones that we consistently get good clinical responses from and they are listed below.

1. The first one by Plant Health, REM 500 we prescribe for sleep.

2. The second one by Plant Health, Nutritional Tincture 2000 mg is full spectrum used mostly for pain.

3. Valo product is a capsule with 25 mg of CBD and 1 mg of Melatonin (works amazing for sleep in most patients)

4. The last one in the picture is from Pachamama in Colorado, which contains an FDA approved amount of THC, is full spectrum and they target pain with pepper, sleep with valerian, anti-inflammatory with turmeric and more.

Our topical CBD from Plant Health works wonders for local pain. Due to the fact that many CBD products do not work, have contaminants and dont meet label claims, CBD gets a bad name. Please only use reputable products where you can see the third-party testing for purity. From there dosing depends upon your needs and everyone doses slightly different to titrate to their benefit.

Dr. Theresa Ramsey is a practicing physician, speaker, lifestyle expert, author of the best-selling book, Healing 101: A Guide to Creating the Foundation for Complete Wellness & a guest expert on Arizonas top morning television show, Your Life A to Z, as their Medical Expert since 2007. Selected as a Certified Hormone Specialist, serving both local and out of state patients as her approach is Evidence Based and her prescribing is like nobody else in the valley when it comes to Quality of Life Enrichment as well as significant Aging Risk Reduction. Most physicians and lay people are uneducated on the safety and necessity of supporting our aging process which is considered a deficient state. Her prescribing is risk free. Dr. Ramsey has also been chosen as one of Phoenix Magazines Top Doc, was chosen as the Natural Choice Awards winning (1) Top Naturopathic Physician, (2) Top Womens Health Specialist and (3) Top Best Holistic M.D. in 2012 and 2013. She is also an eHow health expert. Dr. Ramsey elegantly bridges the gap between Allopathic & Naturopathic medicine as she has worked as an RN for 10 years before pursuing her career as a physician and appreciates what both sciences have to offer. The 10 years that she worked as a Registered Nurse was in Heart Surgery and ICU and then transitioned into Functional Medicine in 1996. An understanding of the cause of dis-ease is paramount in her education and inspiration for those seeking disease prevention and reversal. Her focus in her clinical practice is in Preventive Aging with Bio-Identical Hormone Replacement Therapy. Her second book, The Hormone Book covers all of the rich history through research on HRT prescribing and is anticipated to be released in the fall of 2020. https://revitalizeparadisevalley.com/: 480.970.0077.

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Benefits and Risks of Using CBD Products | Your Life Arizona - AZFamily

Menopause Treatment: Hormone Therapy & Other Remedies – HealthCentral.com

How to avoid panicking with coronavirus outbreak – ABC News

The World Health Organization just declared the novel coronavirus a pandemic.

In the past few weeks, weve seen schools closed, events canceled, transportation services halted and stores emptied of sanitation products. These disruptions are not caused by the outbreak itself but rather peoples response to the outbreak -- a public panic or "mass hysteria."

"When our wellbeing is endangered, we are easily influenced by behaviors of others who face similar endangerment," Dr. Shinwoo Kang, a psychiatrist in New York City, told ABC News. "Although technological and social advances have allowed people to be better prepared, it has also created as much anxiety, amplified by incorrect statements or egregious opinions."

When panic is present, people tend to become doubtful, fearful, pessimistic. Panicked people subconsciously make reactionary decisions to avert risk without stopping to think about the consequences of their actions. We have witnessed this first hand -- residents stocking up on hand sanitizer, toilet paper and bleach in bulk, or hoarding face masks needed by hospitals for medical personnel -- despite repeated announcements from health agencies not to do so.

Shelves of paper products sit nearly empty at a Target in Alexandria, Virginia, March 12, 2020.

The massive stock market volatility of the last few weeks, including the worst week since the 2008 financial crisis, is another example.

A study from Oxford University published in the journal Nature Neuroscience helps explain what panic does to the human brain. Researchers found that when panic and anxiety are present, these stimuli create a glitch in the brains higher-order decision-making center. More simply said, anxiety and panic can cloud our judgment.

Individuals under high stress may struggle to gauge environmental cues that could help them avoid worse outcomes, according to the Oxford researchers.

Additionally, neuroscientists at the University of Pittsburgh have found that anxiety and panic disrupt neurons in the prefrontal cortex -- the area of the brain responsible for decision making -- and that can affect long-term planning, understanding rules, calculating the consequences of various risks and rewards, regulating emotions and problem solving.

"Panic leads your brain to think with emotion rather than intellectual higher processes of your brain," said Mona Degan, a primary care physician in Los Angeles. "This can lead to irrational decisions, especially if we are part of a large group of people trying to do the same thing, such as stocking up on household supplies, which leads to unnecessary shortages."

Panic prevention should be a crucial goal of emergency management, because panic is contagious and destructive.

A woman covering her face walks down Whitehall, as a meeting takes place addressing the government's response to the coronavirus outbreak at Cabinet Office in London, March 12, 2020.

Outbreaks from recent history have evoked similar responses, including Severe Acute Respiratory Syndrome (SARS) in 2002 and Middle East Respiratory Syndrome (MERS) in 2012.

So why does mass hysteria impede more appropriate responses to containment?

"Anxiety triggers our bodies to go into flight-or-fight mode, a natural human response to danger, which in turn secretes cortisol," a stress hormone, Degan explained. When activated, stress hormones can hinder a person's immune system.

Excess anxiety also can affect other hormones, including adrenaline, said Dr. Alexander Sanchez, a psychiatrist in New York City.

"This imbalance of hormones can lead to the areas [of the brain] responsible for making responsible decisions, like the prefrontal cortex, to lose function," Sanchez added. "People lose sense of proportion and start to imagine the worst possible scenario, even if it is unlikely."

It also can lead to xenophobia and discrimination, even though, as Degan reminded us, "This virus does not infect people based off race -- anyone is susceptible."

"It is important to keep calm and act logically in the face of a potential crisis. Take a moment to take a deep breath," Sanchez said. "Read the recommendations from a trustworthy news source, develop a rational plan and then try not to dwell on all the possibilities.

"What you should do instead is all of the things that we know help people to relax in general: Get good sleep, eat well and exercise if you are healthy enough."

Yalda Safai M.D., M.P.H., is a psychiatry resident in New York City and a contributor to the ABC News Medical Unit.

See more here:
How to avoid panicking with coronavirus outbreak - ABC News

How to avoid panicking in coping with coronavirus outbreak – Abccolumbia.com

"Develop a rational plan and then try not to dwell on all the possibilities."

By Dr. Yalda Safai

ABC News The World Health Organization just declared the novel coronavirus a pandemic.

In the past few weeks, weve seen schools closed, events canceled, transportation services halted and stores emptied of sanitation products. These disruptions are not caused by the outbreak itself but rather peoples response to the outbreak a public panic or mass hysteria.

When our wellbeing is endangered, we are easily influenced by behaviors of others who face similar endangerment, Dr. Shinwoo Kang, a psychiatrist in New York City, told ABC News. Although technological and social advances have allowed people to be better prepared, it has also created as much anxiety, amplified by incorrect statements or egregious opinions.

When panic is present, people tend to become doubtful, fearful, pessimistic. Panicked people subconsciously make reactionary decisions to avert risk without stopping to think about the consequences of their actions. We have witnessed this first hand residents stocking up on hand sanitizer, toilet paper and bleach in bulk, or hoarding face masks needed by hospitals for medical personnel despite repeated announcements from health agencies not to do so.

The massive stock market volatility of the last few weeks, including the worst week since the 2008 financial crisis, is another example.

A study from Oxford University published in the journal Nature Neuroscience helps explain what panic does to the human brain. Researchers found that when panic and anxiety are present, these stimuli create a glitch in the brains higher-order decision-making center. More simply said, anxiety and panic can cloud our judgment.

Individuals under high stress may struggle to gauge environmental cues that could help them avoid worse outcomes, according to the Oxford researchers.

Additionally, neuroscientists at the University of Pittsburgh have found that anxiety and panic disrupt neurons in the prefrontal cortex the area of the brain responsible for decision making and that can affect long-term planning, understanding rules, calculating the consequences of various risks and rewards, regulating emotions and problem solving.

Panic leads your brain to think with emotion rather than intellectual higher processes of your brain, said Mona Degan, a primary care physician in Los Angeles. This can lead to irrational decisions, especially if we are part of a large group of people trying to do the same thing, such as stocking up on household supplies, which leads to unnecessary shortages.

Panic prevention should be a crucial goal of emergency management, because panic is contagious and destructive.

Outbreaks from recent history have evoked similar responses, including Severe Acute Respiratory Syndrome (SARS) in 2002 and Middle East Respiratory Syndrome (MERS) in 2012.

So why does mass hysteria impede more appropriate responses to containment?

Anxiety triggers our bodies to go into flight-or-fight mode, a natural human response to danger, which in turn secretes cortisol, a stress hormone, Degan explained. When activated, stress hormones can hinder a persons immune system.

Excess anxiety also can affect other hormones, including adrenaline, said Dr. Alexander Sanchez, a psychiatrist in New York City.

This imbalance of hormones can lead to the areas [of the brain] responsible for making responsible decisions, like the prefrontal cortex, to lose function, Sanchez added. People lose sense of proportion and start to imagine the worst possible scenario, even if it is unlikely.

It also can lead to xenophobia and discrimination, even though, as Degan reminded us, This virus does not infect people based off race anyone is susceptible.

It is important to keep calm and act logically in the face of a potential crisis. Take a moment to take a deep breath, Sanchez said. Read the recommendations from a trustworthy news source, develop a rational plan and then try not to dwell on all the possibilities.

What you should do instead is all of the things that we know help people to relax in general: Get good sleep, eat well and exercise if you are healthy enough.

Yalda Safai M.D., M.P.H., is a psychiatry resident in New York City and a contributor to the ABC News Medical Unit.

Original post:
How to avoid panicking in coping with coronavirus outbreak - Abccolumbia.com

This diagnostics startup is revolutionising cancer treatment in India – YourStory

In India, one woman is diagnosed with breast cancer every four minutes, accounting for 25 to 32 percent of all female cancers across the country. Furthermore, only 60 percent of women who are treated for breast cancer, survive for at least five years post-treatment in India as compared to 89 percent in the US. While these statistics paint a grim picture, a Bengaluru-based startup, OncoStem, is trying to turn things around.

Dr Manjiri Bakre, has a postgraduate doctoral degree in cell biology, OncoStem was built with a vision to develop innovative and affordable tests to personalise cancer treatment.

Dr. Bakres earliest encounter with breast cancer was during her PhD days, when a friend was diagnosed. But since it was diagnosed early, the tumour could be removed. However, soon the cancer relapsed, and spread to multiple organs. It was so sudden; we tried helping by sending her for various therapies, even non-traditional ones, but nothing helped, she says.

The sudden demise of her friend got Dr Bakre thinking about why, despite early detection, so many patients like her friend were unable to survive? When the tumors are small and detected early, typically, such patients should be doing well, she says.

During this time, companies in the West were developing tests that could analyse tumor biology and determine the risk of relapse in patients with early-stage breast cancer. These tests could help personalise a patients treatment plan based on their individual risk of relapse.

However, since these tests were very expensive, Dr. Bakre approached doctors in India and pitched her idea of developing a home-grown and affordable version of a similar test, which eventually led to the birth of OncoStem in 2011.

OncoStems flagship product, CanAssist Breast, is a machine learning-based prognostic test that helps personalise treatment for early-stage breast cancer patients who are hormone receptor-positive (HR+) and HER2-negative. It took 7+ years to develop, validate and get international accreditations for CanAssist Breast before going to market.

CanAssist Breast analyses a patented combination of five biomarkers, digitises historical medical records of patients, feeds into an AI-algorithm and produces a risk score. This score is used to categorise patients based on the risk of cancer recurrence clearly as either 'low or high' with no grey area in between. Patients classified as low-risk can potentially avoid chemotherapy, its costs, and side-effects. CanAssist Breast is performed in OncoStem's NABL and CAP-accredited laboratory in Bangalore. The product is also CE marked.

If the patient is low-risk as per CanAssist Breast, they can avoid chemotherapy and in turn its associated side-effects and financial burden. Chemotherapy can affect multiple different body parts causing nausea, hair loss, infection, anemia, appetite changes, fatigue nerve and muscle problems, urinary bladder and kidney problems, and fertility problems. Febrile neutropenia, a life-threatening complication, is a serious side effect of many forms of chemotherapy.

CanAssist Breast makes customised treatment possible by analysing the patients tumor in depth, and providing a patient specific report indicating if the patient has low or high risk of cancer recurrence. This clear distinction of patients based on risk of cancer recurrence allows doctors to devise chemotherapy treatment in tune with the prognosis, maintaining a balance between the benefits and side effects.

Most tests available in the market that help decide if chemotherapy is required, are from the USA and in turn prohibitively expensive and not validated on Indian patients, Dr Bakre says, adding that CanAssist Breast, launched recently, is the only test validated on Indian patients and is also the most affordable option available currently anywhere in the world at 1/5th the cost of competing tests available in the US.

OncoStem performed a study which is published in Indian Journal of Surgical Oncology, to assess the impact of CanAssist Breast on treatment of early-stage breast cancer patients. In it, they found that CanAssist Breast helped 70 percent of early-stage breast cancer patients avoid chemotherapy. Not only did these patients avoid the physical hardship, but also the financial toxicity of chemotherapy. Moreover, with 93 percent of doctors complying with the test recommendation of avoiding chemotherapy, showed that physician confidence in the test is high.

Since its founding, OncoStem has grown leaps and bounds. Based in Bengaluru, Dr Bakre today has a team of 35 people, including Pathologists, scientists and statisticians, who worked on CanAssist Breast and continue to work on new products and a sales team spread across the country.

However, this upward trajectory had to overcome its share of challenges, particularly when it came to fundraising.

Finding space to set up her laboratory to get the deep science based R&D work going was also a tough task. After months of searching for the ideal space, her investors kindly offered to use part of their office space to set up the laboratory.

Next came the daunting task of working with hospitals and doctors, especially when the company had no track record. Convincing the doctors of the science was the key to get them interested in working with us. I must have approached 50-60 hospitals to work on developing and validating CanAssist Breast, which ultimately led to 10+ large hospitals signing up.

OncoStem's mission is optimising treatment for cancer patients and helping to avoid overtreatment. Dr Bakre says that every member of her team has had interactions with their user base, and has direct knowledge of what information doctors are looking to get from their test, how to improve the user experience, etc. We also are in constant touch with our patients to counsel them, explain the test and follow up on them. OncoStem wants real world evidence of how the test is performing. So they ask patients who took the test if their treatment was as per the test result (i.e no chemotherapy if they were low risk), and also how patients are faring. OncoStem uses this data to publish new clinical utility and decision impact studies.

In the near future, OncoStem plans to expand access to CanAssist Breast to South East Asia & Middle East, while working on the complete automation of CanAssist Breast so that it can be packaged as a Kit in the future. We are also working on developing new tests for two additional cancers and partnering with hospitals across India to clinically validate these tests. We currently have a solution for hormone-positive breast cancer that is already in the market and are working on another subtype of breast cancer as well as ovarian cancer, she concludes.

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This diagnostics startup is revolutionising cancer treatment in India - YourStory

How to Boost Your Immune System During the Coronavirus Outbreak – Thehour.com

Photo: Philipp Nemenz | Getty Images

How to Boost Your Immune System During the Coronavirus Outbreak

The following article is written by Ben Angel. Author of the book, Unstoppable: A 90-Day Plan to Biohack Your Mind and Body for Success. Buy it now from Amazon | Barnes & Noble | iBooks | IndieBound. And be sure to order The Unstoppable Journal, the only journal of its kind based on neuroscience, psychology and biohacking to help you reach your goals.

As we all grow accustomed to life in the age of novel coronavirus COVID-19, and scientists continue working on antivirals and vaccines,many experts are suggestingthe public take a holistic approach to general health maintenance. And as biohackers know better than most, positiveimmune responsecan beessential to staying healthy.While the following suggestionsare not ways to prevent you from contracting the virus, they areeasyways to keep yourself as healthy as possible.

As noted in a recent studyfrom the Sleep Foundation, "Without sufficient sleep, your body makes fewer cytokines, a type of protein that targets infection and inflammation, effectively creating an immune response. Cytokines are both produced and released during sleep, causing a double whammy if you skimp on shut-eye. Chronic sleep loss even makes the flu vaccine less effective by reducing your bodys ability to respond."

onsequently, the study advises taking two 30-minute-or-less daily napsto help mitigatesleep deprivation's effects on the immune system. But if you're having a difficult time getting to sleep, you can try the many binaural beats found on YouTube (Jody Hattons Power Napsis a good place to start)to help grab some winks on your coffee break.

Getting rid of sugar biohacks your immune system by removing a food source for the bad bacteria in your gut that can kill off your good bacteria. Autoimmune problems anddigestive issues are telltale signs of gut imbalance. Ideally, your gut should be 85 percentgood bacteria or probiotics.

You can check for gut dysbiosis through gut-microbiome tests from companies like Thryve Inside, as well as take stock of what youre eating on a daily basis. Fermented foods like sauerkraut, kombucha and kimchi can all help repopulate the good bacteria in your gutas well, leaving you with more energy and vitality.

Its been known for centuries that fasting has been used as a health protocol. Paracelsus, a great healer in the Western tradition, wrote 500 years ago that,Fasting is the greatest remedy, the physician within. In 2014, Dr. Valter Longo of the University of Southern California discovered that fasting for threedays (having nothing but water) could essentially reset the immune system. As summarized on Humann.com, holding off on eating for at least 16-18 hours after your last meal allowsyour bodys attention to become "focused on the current immune cells, recycling them and getting rid of the damaged cells. This means that during the fast, your body is running lean and mean with its white blood cells."

This practice, of course, should only be done if youre already healthy. But provided that's the case, who wouldnt want more time to completeprojects at workand get healthier at the same time?

Stress causes an inflammatory response within the body that can greatly affect your fight-or-flight response by releasing too much of the stress hormone cortisol. It also leaves us more vulnerable to infections and disease, both in and out of the office. That's why mindfully meditating has become a must forany biohacking entrepreneurs. There arevarious forms of mindfulness practices, ranging from the slow-moving poses ofyoga and tai chi to myriad breathing techniques. And arecentstudyinTranslational Psychiatry adds that "there seems to be something intrinsic about meditation itself that can shift gene expression and even boost mood over time."

Many airlines are now monitoring travelers's health before and after flights. According to the CDC, those with no respiratory symptoms do not need to wear a medical mask. The CDC also recommends the use of masks for people who have symptoms of the virus and for those caring for individuals who have symptoms, such as cough and fever.

In his book, Cockpit Confidential, author Patrick Smithstates that in an airplane, Between 94 and 99.9 percent of airborne microbes are captured, and theres a total changeover of air every two or three minutes far more frequently than occurs in offices, movie theatersor classrooms.

This is all the more reason why taking your vitamins during stressful times is important, since many of our essential minerals and vitamins can become depleted during stress. Vitamins C,B and D, as well as zinc,all support your immune system. Research shows that zinc alone can help keep inflammation at bay so that your immune response is better supported.

Related: Coronavirus and a Looming RecessionHow to Raise Capital in Uncertain Times

Although we are in uncertain times, we dont have to wait to see if we are healthy enough to overcome any type of sickness or disease. By implementing some of these holistic steps to boost your immune system, it will inevitably be a win-win situation for not only your health and well-being, but for keeping your business running like a well-oiled machine.Bottom line: Dont panic, and take advice from the medical professionals who are specialists in this area.

This article solely reflects the opinion of the author and is not intended as an alternative to recommended official government guidelines. For more updates and information about the novel coronavirus, visit the CDC's website.

Are you ready to become unstoppable?

Visit http://www.areyouunstoppable.com and take your FREE 60-second online quiz now. By answering a series of simple questions, my software will analyze your results and provide you with a comprehensive report that will indicate your identity type and lead you to the tools and tips you need to close that gap between who you are and who you could be. Take the quiz to get started!

Related:Amazon Asks All Employees to Work From Home#4 Tips On How To Effectively Pitch Your Story To The Media HousesDelivery Apps, Ride Hailing Firms Call For Caution Amid Coronavirus Scare

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How to Boost Your Immune System During the Coronavirus Outbreak - Thehour.com

Friday the 13th and Fear of Coronavirus: The Positive Mindset I Hope We’ll Adopt – Christianheadlines.com

Friday the 13th and Fear of Coronavirus: The Positive Mindset I Hope We'll Adopt

On average, there is a Friday the thirteenth every 212 days. Such a day occurs in any month that begins with a Sunday. Fear of this day has been given the scientific name, paraskevidekatriaphobia, from the Greek words for Friday, thirteen, and fear.

By contrast, we dont yet have a scientific name for fear of coronavirus, but that makes such fear no less real. Or less dangerous.

Sophie Trudeau, wife of the Canadian prime minister, has tested positive for coronavirus. The Capitol, White House, and Supreme Court have been closed to the public.

US stocks had their worst day since the 1987 stock market crash. The NCAA canceled its basketball tournaments for the first time in history. All eleven Disney theme parks in North America, Europe, and Asia have been closed. The PGA has canceled the Players Championship and the next three events on the schedule.

These are frightening days, indeed.

One psychologist notes, Fear influences how we react to media coverage of health hazards. In times of anxiety, we tend to pay more attention to threat-related information, which drives up our anxiety and distress.

This bias for threat can exacerbate our reaction to the disease, leading to panic. And panic is an irrational fear reaction that, by definition, your bodys reaction and adrenaline response take over from your ability to actually rationally evaluate the situation.

Responding appropriately to fear is therefore vital not just for our psychological wellbeing but for our physical health as well.

According to Cleveland Clinic, stress causes our bodies to produce greater levels of the hormone cortisol and can cause anxiety and depression. These can lead to elevated inflammation that can compromise our immune system.

Stress also decreases the bodys lymphocytesthe white blood cells that help fight infection. The lower our lymphocyte level, the more we are at risk for viruses such as SARS-CoV-2, the virus that causes COVID-19.

Since, as one professor notes, the main way we relate to information about the world is through feelings and gut intuitions, it is vital that we focus on objective medical advice and practical steps we can take today.

And it is vital that we turn to resources that can provide peace we cannot produce ourselves.

This week, weve focused on ways the Christian faith uniquely helps us in times of crisis such as the coronavirus pandemic. Weve discussed Jesus responses to our prayers, his invitation to trust him with our fears, the power that comes from submitting to the power of God, and the relevance and hope found in Christian community.

Unfortunately, many in our culture believe we have a binary choice: we can trust God or we can trust science, but we cannot do both. This is a false dichotomy.

Scientists use minds and abilities given to them by the God who calls us to steward his creation with excellence (Genesis 2:15; Philippians 4:8). Christianity has made dramatic contributions to the development of hospitals and the advancement of medical care.

According to a University of Chicago study, 76 percent of doctors say they believe in God and 55 percent say their religious beliefs influence their practice of medicine.

It is a mistake for scientists to discount Gods wisdom, just as it is a mistake for Christians to discount scientific wisdom. The Great Physician uses physicians in his continued ministry on earth.

In John 4, it says that Jesus had to pass through Samaria (v. 4). As you may know, Jews typically avoided Samaria on their way from Judea to Galilee and vice versa.

But Jesus went where other Jews would not go. In fact, had to translates a Greek word meaning must or to be necessary. Every time we find this word in Johns Gospel, it indicates divine direction and necessity (cf. 3:7, 14, 30; 9:4; 10:16; 12:34; 20:9).

Jesus had to pass through Samaria because his Father sent him to those who could not or would not come to him. Our Lord now continues his earthly ministry through us. We are his hands and feet, the physical expression of his spiritual presence (1 Corinthians 12:27).

As a result, here is the positive mindset I hope well adopt: lets join God as he is already at work in this crisis.

He calls physicians just as he calls pastors. He uses their expertise to advance his healing ministry in our broken world. Lets pray for them, encourage them, and follow their guidance.

In addition, he calls us to use our gifts, abilities, resources, and influence in proactive ways as he leads and empowers us. People may be more open to their need for God now than they were a month ago. They may be more aware of their mortality and limitations. They may be more willing to seek help. And they may be more open to our witness and compassion.

The coronavirus pandemic is indeed unique and frightening., but it also presents a unique opportunity to take Christ to our frightened culture. The God who redeems all he allows wants to redeem this physical threat for eternal spiritual good.

How can you join him today?

Publication date: March 13, 2020

Photo courtesy: Getty Images/Elena Volf

For more from the Denison Forum, please visit http://www.denisonforum.org.

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Friday the 13th and Fear of Coronavirus: The Positive Mindset I Hope We'll Adopt - Christianheadlines.com

Varicose Veins: Everything You Need to Know About How They Form Expert Advice – Allure

Varicose veins are incredibly common especially among adult women and they are also distinct in appearance: Blue, purple-tinted twists and turns underneath the skin, which usually take shape on the legs. For some people, varicose veins are merely a cosmetic issue (that can easily and quickly be fixed, thanks to advancing technologies and approvals by the Food and Drug Administration). While for others, the presence of these swollen, enlarged veins can bring on a host of painful side effects.

Here, we asked a handful of experts to explain everything about varicose veins, including what they are in the first place, why they form, and the potential risk factors that contribute to their development. If you're an adult of any age but especially if you've ever taken oral contraceptives this is what you need to know about varicose veins.

In simple terms, varicose veins are veins that become enlarged, twisted, and pooled with blood (which gives them their distinct bluish, purple-colored appearance). Technically speaking, "varicose veins are a condition where the deeper, large veins of the legs stop working normally and cause the vein to back up with blood, [thereby] becoming stretched out and dilated," explains George Skandamis, a board-certified dermatologist in Ohio.

The result of this backlog is swelling of the veins, which causes them to become visible on the surface of the skin. Varicose veins are often diagnosable simply by their appearance, although your doctor may use an ultrasound to confirm that the valves aren't working properly.

Varicose veins can range in severity from thin, threadlike veins (spider veins) to "deeper vessels called reticular veins which appear as medium-sized bluish veins under the skin," explains Laura Haygood, a board-certified dermatologist in Tyler, Texas. "The largest deep connecting varicose veins are not usually visible unless special ultrasound devices are used. " Varicose veins are most commonly found on the lower leg and inner thighs, as well as the shins, calves, and ankles (we'll explain why).

For some people, varicose veins are purely a cosmetic issue. For others, however, varicose veins can cause potentially debilitating physical symptoms like pain, aching, cramping, and restless legs. They might also cause the skin to become irritated or itchy, and some research suggests these symptoms can potentially worsen in warmer weather.

To understand what causes veins to become varicosed, it helps to first understand the body's venous system. Our veins, when functioning properly, operate as one-way streets: Moving blood from our peripheries (legs, arms, everywhere else) back to the heart.

Healthy veins "have little trap-door valves that don't allow blood to go backward," Skandamis explains. "When the vein is overworked from having to push blood up the body against gravity, the valves seals become leaky and blood is allowed to go backward, leading to the vein becoming enlarged."

This explains why varicose veins almost always occur on the legs because when we're standing or sitting, our veins have to work against gravity to do their job. "As gravity pulls everything down, veins tend to accumulate blood and it becomes harder for blood to travel upwards back towards the heart," says Danny Del Campo, a board-certified dermatologist in Chicago. "As time goes on, this backup of pressure leads to collapse of valves in the veins."

Varicose veins often develop as part of the aging process, after years of "increased venous pressure caused by standing or sitting in one position for prolonged periods," explains Haygood.

Other potential risk factors for developing varicose veins include, "family history, pregnancy, lack of exercise, and weight gain," she says.

Everyone, but especially those who are pregnant and/or have had more than one child, are at a higher risk for developing varicose veins than the general public. In fact, varicose veins affect nearly twice as many women as men, and spider veins may be an issue for half of all women, according to the U.S. Department of Health & Human Services Office on Women's Health. Why?

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Varicose Veins: Everything You Need to Know About How They Form Expert Advice - Allure

Transgender in Idaho: a conversation with two trans women on House Bills 500 and 509 – KPVI News 6

Two bills that would affect transgender Idahoans are moving through the Idaho Legislature. KPVI spoke with two transgender women, and a doctor specializing in transgender patients, about the legislation.

Meet Katie Burdick.

She works at a local call center and moved to Pocatello at 18 years-old. Burdick says she first knew she was a girl at four-years-old.

I had this epiphany, says Burdick. I believeclose to my exact words were: Mom. Im a girl.

But while Burdicks mom is super accepting today, at the time, she wasnt.

She wasnt too keen on it then, I was young and it was a very conservative time, says Burdick.

I had two parents who love me, but they didnt understand.

20 year-old Rosetta Roberts had a similar experience.

I dont really talk to my family anymore because I dont have that much acceptance from them, says Roberts. They still mis-gender me. My mom tries to gender me correctly, which I greatly appreciate, but it still hurts and I avoid her.

Roberts is an Idaho State University student double-majoring in computer science and applied mathematics. She hopes to one day be a professor.

She says she didnt realize she was transgender until 17-years-old, when she moved out of her parents home.

Id heard about it [transgender people], but I had the misconception that they were just men wearing dresses at the time.

Even though she didnt know the word for it, she knew something was wrong.

I started having dysphoria around when I started to hit puberty and things just didnt feel right, says Roberts.

I felt like my body was fighting me and that it wasn't going the direction that I wanted.

House Bill 500

January 19, 2015 and April 23, 2018 are significant dates for Burdick and Roberts.

Roberts says April 23 is more important to her than her birthday.

"That's when my life turned around, that's when I started feeling happy," says Roberts.

Thats the date she started hormone treatments to become a woman.

Very quickly I felt a lot better in the head, says Roberts. Its also had visual effects on my appearance, which Ive grown to love. I love my body now. I still sometimes struggle with not loving my body but Im usually pretty confident now.

For Burdick, January 19 was the start of what would become a long medical journey.

Ive always wanted to be as womanly as I can, so at 24, 25, 26, the hormones werent really taking and so I was kind of still mildly depressed, says Burdick. But about a year ago they started to take effect. From an emotional standpoint I was so much happier.

Both women are now living their most authentic lives, but are worried about legislation like House Bill 500 which would ban transgender women and girls from female sports.

"I think it's archaic and almost draconian," says Burdick.

Representative Barbara Ehardt of Idaho Falls is the bill's sponsor.

She says the legislation is about protecting women and girls.

"It's been disheartening to watch through the years this slow but fast infiltration of biological boys and men participating in women's sports," says Ehardt.

Ehardt cant name an active Idaho case of a transgender woman or girl taking advantage of her strength in female sports, but says its only a matter of time before it happens.

She points to an active lawsuit in Connecticut in which three girls are suing two transgender sprinters who have frequently outperformed their cisgender competitors, according to NBCs Connecticut affiliate.

(You can read more about that case here: https://www.nbcconnecticut.com/news/local/girls-sue-to-block-participation-of-transgender-athletes/2222777/)

The NCAA and the Idaho High School Activities Association lets transgender girls and women to play on girls or womens teams if theyve been on testosterone suppression drugs for at least a year.

Ehardt says thats not enough. House Bill 500 sites a 2019 study from the Karolinska Institute which found that "Muscle strength, size and composition following 12 months of gender-affirming treatment in transgender individuals: retained advantage for the transwomen.

Doctor Neil Ragan has specialized in transgender care for seven years, and he now sees around 143 transgender patients from across southeastern Idaho. He pushes back on the Karolinska study sited in House Bill 500, saying thisissue is more nuanced thanhow it's being approached.

In my opinion they're picking and choosing, says Dr. Ragan. And you can find a study that will support any position that you want to take."

What I have observed with my own transgender women on estrogen is that their body strength clearly declines, says Dr. Ragan.

He also points out that theres a broad range of natural strength in both the male and female sex.

Burdick can relate to this.

Even though I was born with a male chromosome the hormones can work wonders, says Burdick. There are cis-gender women who are stronger than me and Im stronger than some cis-gender women.

The bill also includes a section about establishing an athlete's sex if its called into question.

The bill text says:

A student may establish sex by presenting assigned physician's statement that shall indicate the student's sex based solely on:

Dr. Ragan and other transgender advocates worry these examinations could be invasive.

Ehardt calls this a false narrative and misguided. She claims the test would be no more invasive than a routine physical, a cheek swab or a urine test.

But Dr. Ragan says it isnt always that simple.

These exams may not prove anything. There is such a thing as an intersex condition, disorders of sexual development, babies are born and you cant tell initially what sex or what gender they are. Sometimes that is an adrenal issuethere are people who have chromosomal abnormalities, says Dr. Ragan.

"The diversity in human biology is astonishing and I think that when we start trying to legislate who fits into what category, we're going to have difficulty because there will be people who dont fit neatly into either categories."

Ehardt argues that sex cannot be fluid. We are not taking away your ability to identify. You can still identify however you want. But you will have to compete under the category of your biological sex.

Roberts says it's about letting people pursue their dreams.

"I dont want these people to be blocked from their dreams. I myself have dreams if I was blocked from my dreams I would be really really hurt. I don't think transgender people in sports should be blocked."

House Bill 509

Burdick destroyed her childhood photos.

"At first it was like almost anger but then it very quickly went into like a peace and serenity of 'this is gone now'," she says.

Burdicks parents wouldnt allow her to transition, so she was forced to go through male puberty.

"It was just a part of me that I'm like 'I don't even want to look."

Roberts was also forced to grow up in a boy's body.

It made me depressed and I felt more like my body was a vehicle for my head than like a part of me. It felt like puberty was destroying my body.

Roberts can't change her past, but after a 2018 court ruling, she could change the sex on her birth certificate, which saysprotects her frombeing outed.

"One of the big problems with being trans, is that if people find out, a lot of people often become discriminatory," says Roberts.

Blackfoot Rep. Julianne Young sponsored House Bill 509, which would ban changes to sex on birth certificate after a year.

She says this would protect the state's population records.

In a statement Young says:

"Safeguarding the accuracy of our vital records is a vital part of protecting the public health and safety. In addition, many public and private policies and contracts rely on a biologically informed definition of sex.

Dr. Ragan doesnt agree with that argument.

"The sheer number of transgender patients...the number is so small it's not going to significantly skew the demographics."

Many transgender people change theirsex on other documents like drivers licenses or social security documents.

I haveall my insurance cards changed. I have legal name changed. An affidavit from Dr. Ragan saying Im legally female, says Burdick.

Dr. Ragan believes its vital that transgender people have consistent documentation.

"In order for an individual to comfortably navigate this complicated world we live in it's really important that all of their documents align."

Living comfortably sounds good to Roberts.

"I just don't want them to bother us. I want to not have to worry about things like this."

In an email to Rep. Young, Roberts asked her to stop sponsoring the bill. She never heard back.

KPVI also reached out to Rep. Young for further comment, and never got a response.

Looking Forward

Both Roberts and Rosetta say they want to move out of Idaho.

Maybe even the U.S. eventually, says Roberts.

I dont like the atmosphere that the government has towards transgender people.

Roberts has a message for Rep. Young andEhardt:

The bills that theyre sponsoring are very very hurtful to the trans community and I would ask them to stop sponsoring these bills, and to try to help the trans community as much as possible.

Burdick says she wants to live in a bigger city because she feels people are ignorant, especially at the highest levels of government.

Because they have that power, they dont really get stuff. I think they put aside the hoi polloi, the common people.

Like Roberts, Burdick hopes Idaho politicians will start focusing on legislation to help transgender people, like creating more safe spaces for transgender youth.

Try to have more empathy try to listen and understand, she says.

When asked what shes done with support the trans community, Ehardt says shes been working on curbing LGBTQ youth suicide.

Burdick hopes to educate people as much as possible.

I think educating people about transgender issues and rights is a good thing. Yelling back doesnt work, says Burdick.

She wants people to know that Were not cross dressers. Were not drag queens. Were not putting on a show.

Both House Bill 500 and 509 have passed the Idaho House of Representatives.

500 will be discussed in the State Affairs committee Friday. House Bill 509 is also set to be heard in the same committee.

Link:
Transgender in Idaho: a conversation with two trans women on House Bills 500 and 509 - KPVI News 6

U.S. Will Drop Limits on Virus Testing, Pence Says – The New York Times

All federal limits on testing will be lifted, Pence says.

Vice President Mike Pence said the Centers for Disease Control and Prevention was lifting all restrictions on testing for coronavirus, and would be releasing new guidelines to fast-track testing for people who fear they have the virus, even if they are displaying mild symptoms.

Today we will issue new guidance from the C.D.C. that will make it clear that any American can be tested, no restrictions, subject to doctors orders, Mr. Pence told reporters at the White House.

The federal government has promised to significantly ramp up testing, after drawing criticism for strictly limiting testing in the first weeks of the outbreak. But health care supply companies and public health officials have cast doubt on the governments assurances, as complaints continue that the need for testing remains far greater than the capacity.

The estimates were getting from industry right now by the end of this week, close to a million tests will be able to be performed, the head of the Food and Drug Administration, Dr. Stephen Hahn, said at a White House briefing on Monday.

But some companies developing tests say their products are still weeks away from approval.

And even if a million test kits were available, public health laboratories say they would not be able to process nearly that many within a week. A spokesman for the Department of Health and Human Services said on Monday that public health labs currently can test 15,000 people daily, though that figure is expected to grow.

The F.D.A. said that Dr. Hahn was taking into account the anticipated increased production of test kits by an outside manufacturer, Integrated DNA Technologies, which is now selling kits to the federal government and other buyers.

The C.D.C. botched the first attempt to mass produce a diagnostic kit, a discovery made only after hundreds of kits had been shipped to state laboratories. A promised replacement took several weeks, and still did not permit state and local laboratories to make final diagnoses.

Right now, Id say wed need more capacity, Dr. Hahn said at the White House briefing.

The Department of Veterans Affairs confirmed on Tuesday that a veteran had tested positive for the virus and was transferred to the V.A. hospital in Palo Alto, Calif., presenting the federal government with a new challenge a coronavirus infection in its sprawling veterans health care system.

The patient was diagnosed on Monday and is being cared for in isolation, a V.A. spokeswoman said on Tuesday. It was not clear whether local public health officials had already announced the case; Santa Clara County, Calif., has had several previous coronavirus cases, including two announced on Tuesday without any specifics.

The veterans health system, responsible for caring for more than nine million former service members, has been struggling with an overhaul of its $16 billion medical records system, which has been delayed amid technical and training glitches.

Last week, the U.S. military announced its first active-duty case, an American soldier stationed in South Korea, the country with the second-largest coronavirus outbreak after China. In response, Army officials closed the office buildings the infected soldier had used, called off social events on the base and sent clean teams to disinfect anywhere the soldier had been. A civilian employee at another American military base in South Korea has also tested positive for the virus.

[Read: China pushes back as the coronavirus crisis damages its image.]

President Trump said on Tuesday that he may further tighten limits on international travel in hopes of blocking the arrival of more visitors infected by coronavirus, but he ruled out for now any restrictions on domestic travel within the United States.

Were not looking at that at all. Theres only one hot spot, he told reporters. But were looking at other countries and were being very stringent.

The Trump administration has already imposed limits on travel from China, barred all travel to Iran and issued warnings to Americans not to travel to parts of Italy and South Korea.

Later, at the National Institutes of Health, Mr. Trump added that he was not actively considering restrictions on travel to Mexico but expressed concern about Japan, which is hosting the Summer Olympics in Tokyo and has just constructed a new stadium for the competition.

I dont know what theyre going to do, he said. They have this fabulous facility.

As for Mexico, he played down the prospect of travel limits. Were not looking at it very strongly, he said. Were not seeing a lot of evidence in that area.

Two people who died last week in the Seattle area were infected with coronavirus, officials said on Tuesday, suggesting that the virus had spread in that region days earlier than health officials had previously known.

That brought the death toll in Washington State, and in the United States, to nine. So far, those deaths have all been in the Seattle area.

The confirmation of additional deaths adds to an escalating emergency in a region that has rapidly emerged as a focal point for the virus in the United States, where there have now been at least 120 cases of coronavirus in more than a dozen states, as local health authorities from coast to coast raced to assess the risk to schools, medical centers and businesses.

The other deaths, all announced over the last few days, included residents of a nursing care facility in Kirkland, a Seattle suburb.

Health officials in North Carolina announced that states first case of coronavirus on Tuesday afternoon. They said the patient there had traveled to Washington and been exposed at a long-term care facility where there was an outbreak, an apparent reference to the Life Care nursing center in Kirkland, Wash.

The North Carolina patient was said to be doing well and isolated at home in Wake County.

Officials in Washington State were rushing to take steps to contain the spread. Health officials were asking the State Legislature for an additional $100 million in funding to help respond to the virus. Some leaders were weighing more widespread closings of events, and around Seattle, immediate steps were being taken.

In King County, officials were in the process of purchasing a motel in the region that could house people needing isolation. They were also working to repurpose modular homes that had been originally meant to be used by homeless people.

When the coronavirus first broke out in January, its impact on the travel and hospitality businesses appeared limited to China. But the outbreak has now spread to every continent except Antarctica, and the cities and industries that rely heavily on travel and tourism are bracing for pain.

One city that is anxiously watching the spread of the virus is Las Vegas, which had more than 42.5 million visitors last year, 6.6 million of them to attend business conferences, according to the citys Convention and Visitors Authority.

Some big upcoming conferences have already been canceled, including an annual Adobe Systems event with 20,000 attendees and celebrity speakers like Gwyneth Paltrow and Tom Brady. Adobe said it planned to host portions of the event online.

Major companies like Facebook, Twitter and Intel have said their employees will not attend the popular South by Southwest festival in Austin, Tex., which starts next week, but organizers insisted on Tuesday that the festival would go on.

The New York subway will be disinfected every 72 hours, officials say.

If theres one place where being packed in close quarters with crowds of strangers is unavoidable, it is the New York City subway system well known not just to the locals, but to millions of tourists and anyone who has ever watched a television show or movie set in the city. And that makes it a focus of public worry about contagion.

Officials said on Monday that industrial-grade disinfectants would be used to clean everything from train cars to MetroCard machines every 72 hours. The safety of our customers and employees is our first priority as we continue to monitor the coronavirus, said Patrick T. Warren, chief safety officer at the Metropolitan Transportation Authority.

From Monday evening to midday Tuesday, transit workers disinfected nearly all of the systems 472 subway stations, more than 1,900 subway cars and nearly 2,000 buses, officials said. Transit officials in neighboring New Jersey, which has its own vast commuter rail and bus network, have also ramped up its cleaning regimen.

The Centers for Disease Control and Prevention recommends keeping essential services like public transit in operation, in part so that health care workers and other emergency responders can get to work.

Other major cities experiencing outbreaks have announced similar precautions. In Tehran, public health officials have said they are disinfecting buses at least four times a day and cleaning trains after each trip. In Italy, buses, trains and ferries are also being disinfected regularly.

Although research on the coronavirus is still in the early stages, a 2011 study on a possible influenza outbreak in New York City found that only 4 percent of infections would occur on the subway.

Iran frees 54,000 inmates to avoid spread in prisons.

The number of people in Iran infected by the coronavirus surged past 2,300, the death toll rose to 77, and the countrys head of Parliament said that nearly two dozen lawmakers had tested positive and should avoid meeting with members of the public, the authorities announced on Tuesday.

The new tallies were reported as the judiciary, apparently hoping to minimize the risk of contagion in Irans penal system, said it had temporarily freed more than 54,000 prisoners considered to be symptom-free. But it was unclear from the announcement how many of the prisoners had actually been tested, given the shortage of testing equipment in Iran.

Gholamhossein Esmaili, a judiciary spokesman, who announced the prisoner releases, did not specify whether any of the reported cases or deaths so far have included prisoners.

Iran now has 2,336 reported cases, more than any country other than China and South Korea, and 11 more people have died, according to figures cited by the deputy health minister, Alireza Raisi, on state TV.

State news media reported on Tuesday that Ahmad Toysarkani, an adviser to the judiciary, was among those who had died. The virus has been felt at the highest levels of Iranian society, with Masoumeh Ebtekar, the presidents deputy for womens affairs and the highest-ranking woman in the government, among those who have become infected.

Ayatollah Ali Khamenei, the supreme leader, was pictured in state news media wearing plastic gloves, and he told the Iranian people to follow medical advice to help combat the outbreak, saying anything that facilitates its spread is a sin.

The death toll in Italy surges while the pope has a common cold.

The death toll in Italy jumped to 79 on Tuesday, an increase of 27 deaths in one day, Italian officials said.

Those who had died in the previous 24 hours ranged in age from 55 to 101, said Angelo Borrelli, the head of Italys Civil Protection Agency who is coordinating the countrys response to the crisis.

Most were over 70, and some had pre-existing conditions. But for the others, we still arent sure, he said at a news conference in Rome.

Of the 2,502 infections so far up from the 1,835 announced on Monday 90 percent were located in the northern Italian regions of Lombardy, Veneto and Emilia Romagna, Mr. Borrelli said. Italy has had by far the largest outbreak outside of Asia.

Meanwhile, the Vatican said Tuesday that Pope Francis was ailing with a common cold, and did not have symptoms that could be related to other pathologies.

On Tuesday, France, which has the second highest number of cases in Europe, announced 21 new cases of coronavirus on its soil, raising the total number of cases to 212. A top official at Frances health ministry also announced one new fatality from the virus, a 92-year-old man in the western Morbihan region, bringing the death toll up to four.

Gov. Andrew M. Cuomo announced on Tuesday morning a second confirmed case of the coronavirus in New York, saying that a man in his 50s in Westchester County, just outside of New York City, had tested positive.

The man initially went to a hospital in Westchester about four or five days ago, before it was confirmed he had the virus, the authorities said, acknowledging that he may have exposed doctors, nurses and others to the infection.

On Tuesday, health officials told the mans synagogue, Young Israel of New Rochelle, to call off its religious services for the foreseeable future. Citing guidance from state officials, the county also told congregants who attended Shabbat services on Feb. 22 or went to a funeral or a bat mitzvah there on Feb. 23 to quarantine themselves; the county said it would order quarantines if the affected people did not do so voluntarily.

The patient, whose test was confirmed overnight in New York City, is a lawyer who works in Manhattan and lives in New Rochelle. Mr. Cuomo said the new patient had an underlying respiratory illness and is now at NewYork-Presbyterian Hospital in the city. The mayors office said he was in serious condition.

Though he traveled recently to Miami, he had not traveled to any of the areas that are known hubs of transmission for the virus. For New York, this means the new coronavirus can no longer be thought of as an external threat that has yet to arrive.

Health authorities in New York are now scrambling to trace the chain of transmission in both directions: who infected him, and who he may have infected.

Two of the mans children have links to New York City. One child attends a Jewish high school in Riverdale, which was closed on Tuesday as a precaution. The other, a college student in the city who officials believed lives on campus, has exhibited symptoms associated with the illness.

Both of them have been quarantined and are being tested for coronavirus, according to Mr. de Blasio.

On Sunday, officials announced the states first case, a 39-year-old woman in Manhattan who had been visiting Iran, one of the epicenters of the viruss rapid worldwide spread.

Symptoms of the infection include fever, cough, difficulty breathing or shortness of breath, and gastrointestinal problems or diarrhea.

Serious cases cause lung lesions and pneumonia. But milder cases may resemble the flu or a cold, making detection of the more deadly coronavirus difficult.

Current estimates suggest that symptoms may appear in as few as two days or as many as 14 days after exposure.

If you think youre sick, stay home, except to get medical care. If you have symptoms, the C.D.C recommends that you call a medical professional if you have recently been in an area with a coronavirus outbreak, or have had close contact with someone who has been to such an area.

Fed rate cut fails to quell investor fears of a coronavirus hit to the economy.

The Federal Reserve delivered the emergency rate cut investors had been clamoring for at 10 a.m. on Tuesday. The market rally that followed lasted about 15 minutes.

By the end of trading on Tuesday, stocks were sharply lower and bond yields had plummeted to previously unthinkable lows, suggesting that investors think theres little the Federal Reserve can do to keep the coronavirus from hammering the U.S. economy.

The S&P 500 fell about 2.8 percent, undoing much of Mondays 4.6 percent surge. The yield on 10-year Treasury notes dropped below 1 percent.

Both moves suggest investors see growing threats to the outlook for economic growth and corporate profits over the next 10 months.

Economists around the globe sharply downgraded their economic growth expectations for the year. JPMorgan Chase economists and market analysts estimated that investors are pricing in a 90 percent chance of recession, according to a research note published Tuesday afternoon.

India curbs medicine exports, affecting supplies worldwide.

In response to the epidemic, the government of India on Tuesday curbed exports of 26 drugs and drug ingredients, including a wide range of antibiotics and certain vitamins, meaning that the new coronavirus could soon have ripple effects on people worldwide with other ailments.

The world relies heavily on Indias huge pharmaceutical industry for generic drugs, but Indian officials are concerned about safeguarding the supply for their own country.

Indian drug makers depend on Chinese factories for key drug ingredients, particularly for antibiotics and vitamins. The Covid-19 outbreak in China and quarantine of Hubei province, where much of the production is centered, has severely hampered Chinas ability to produce those ingredients.

Although Indian companies had stockpiled extra ingredients ahead of the annual Lunar New Year holiday, those reserves are now running low.

Its unclear whether Indias exports of the specified drugs will be completely stopped. The governments order said that exports of the drugs are restricted, which means a government permit is required before they can be shipped out of the country.

The antibiotics facing export limits are tinidazole, metronidazole, chloramphenicol, erythromycin salts, neomycin, clindamycin salts and ornidazole.

Other drugs on the restricted list include the painkiller acetaminophen, the hormone progesterone, the antiviral drug aciclovir, and the vitamins B1, B6 and B12.

Cruise ship passengers in the U.S. being released from quarantine.

Many of the more than 120 American evacuees from the Diamond Princess cruise ship in Japan were set to be released from quarantine on Tuesday from a military base in Texas, after state and local officials said the C.D.C. modified its release protocol in response to their concerns.

The former passengers have been at Lackland Air Force Base in San Antonio for roughly two weeks since being evacuated from the cruise ship. Those being released have tested negative for the virus and have not shown symptoms while in quarantine.

They were scheduled to go home on Monday, but their release was delayed at the urging of San Antonio and Texas state officials. The city tried and failed to obtain a federal court order barring the C.D.C. from releasing more people.

None of those released on Tuesday will stay at local hotels, city officials said, but instead will be taken on buses from the air base to the airport.

Quarantined people who have been infected must be symptom-free and have two negative test results within 24 hours are eligible for release.

Reporting and research were contributed by Jennifer Steinhauer, Katie Rogers, Christina Goldbaum, Reed Abelson, Sarah Kliff, Azi Paybarah, Jesse McKinley, Katie Thomas, Knvul Sheikh, Choe Sang-Hun, Peter Baker, Benjamin Mueller, Marc Santora, Joseph Goldstein, Michael Gold, Luis Ferre-Sadurni, Eric Schmitt, Helene Cooper, Roni Caryn Rabin, Russell Goldman, Paul Mozur, Raymond Zhong, Noah Weiland, Emily Cochrane, Aaron Krolik, Claire Fu, Elaine Yu, Elisabetta Povoledo, Vindu Goel, Manny Fernandez, Mitch Smith, Patrick J. Lyons, Richard Prez-Pea, Dagny Salas, Iliana Magra and Constant Meheut.

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U.S. Will Drop Limits on Virus Testing, Pence Says - The New York Times

Misinformation That May Be Costing Women Their Lives – Jewish Link of New Jersey

By Warren Slaten, M.D. | March 05, 2020

Menopause is not a disease. It is a normal phase of life that marks the end of the menstrual cycle. However, during early adulthood, women are protected by several hormones including estrogen and progesterone. These hormones help women maintain good heart health and help women maintain their bones. They also help women think clearly. When these hormones are lost at menopause, women become more vulnerable to heart diseases, osteoporosis with hip fractures and Alzheimers disease. These happen to be the three leading causes of death in older women.

Since the famous Womens Health Initiative (WHI) study, which was initially published in 2002, the use of hormones declined dramatically. Thats because the study authors and the media exaggerated the studys negative findings and underemphasized the studys many positive findings. As a result, a mass panic developed about hormone replacement such that most physicians stopped prescribing it and most women wanted nothing to do with it.

Unfortunately, when they stop using hormones, which is the most effective way to prevent the three greatest causes of womens death, women are more vulnerable to these three diseases. There have been several medical journals in the last two years that have published articles highlighting the decreased life expectancy for women as a result of not protecting themselves with hormone replacement.

The most common response I hear when I speak to women about hormone replacement is that they are afraid of breast cancer. However, this is pure myth. Estrogen does not cause breast cancer. In fact, the compendium of studies reveal that estradiol actually mildly reduces the incidence of breast cancer. The one hormone that was associated with breast cancer was Provera, which is a synthetic version of progesterone. The natural or bioidentical version actually protects against cancer as progesterone is anti-proliferative. This means that progesterone reduces the progression of cancers. The ironic thing is that as the subjects continued to be followed over the ensuing five years, even Proveras cancer association weakened, but this did not make for good headlines so even most doctors are not aware of this result. The bottom line is that estrogen does not cause cancer and, if anything, provides some protection against breast cancer. Bioidentical progesterone further protects against cancer.

The other error that many doctors make is the misconception that hormone replacement causes strokes and heart attacks. This is because in the WHI study, some of the older women started on hormone replacement had an increased risk for cardiac events during the first year they took hormones. As noted above, estrogen protects against heart disease and younger women had cardiac benefit in the WHI study. The presumed basis for these events is that estrogen causes clots to be dislodged. The older women in the study were more likely to have clots and once the clot is dislodged, strokes and heart attacks can result. Interestingly, these events tend to occur in the first year. After that, even older women received cardiac benefit from estrogen.

Another source of the cardiac error is that in the WHI study, Premarin was used. Premarin is a truncated word for pregnant mares urine. Animal rights issues aside, the biggest concern about Premarin is that it is a stronger estrogen than estradiol, which is the bioidentical version of what humans naturally produce. As a stronger estrogen, Premarin has a tendency to dislodge clots but no study has ever shown that estradiol has such a tendency. Thus, bioidentical estradiol is not associated with heart attacks or strokes. To the contrary, the relative risk of heart disease for women who take estradiol is 0.4 compared to women who do not take estradiol. That means that if a woman does not take estradiol, she is 2.5 times more likely to get heart disease.

The most costly error is that medical societies and organizations have generally recommended hormone replacement for women only when they are having menopausal symptoms such as hot flashes and to take them for the shortest possible time at the lowest dose that reduces symptoms. However, we have learned that women who have hot flashes are at higher risk of the diseases associated with menopause, including heart disease, osteoporosis and Alzheimers. One study found that women with hot flashes had increased white matter loss on brain MRIs. Even insulin resistance, which is associated with diabetes mellitus, is increased in women with hot flashes. By taking hormone replacement, women significantly reduce the risk of these diseases. The misconception that women should minimize hormone use has deprived them of a key tool to reduce the risk of such deadly diseases.

Women have been led to believe that hormone replacement is very dangerous. Many women do not even consider hormone replacement because of this; I often see a visceral reaction against hormones that is based on misleading information. I am optimistic to see the medical community starting to realize the harm caused by discouraging hormone use.

Menopause is a challenging time for many women. It is often accompanied by weight gain of 10-20 pounds, increased fatigue, insomnia, depression, decreased libido and even increased joint and muscle pain. I hope that women are encouraged that with bioidentical hormones, women can reverse all these symptoms with weight loss, improved energy, improved mood, improved sleep and improved libido. At the same time, women can reduce the risk of the three leading causes of death for older women, including heart disease, osteoporosis with deadly hip fractures and Alzheimers disease. So by starting bioidentical hormone replacement, you reduce your risk of disease and improve your quality of life.

Dr. Slaten is a wellness physician specializing in regenerative pain treatments and lifestyle counseling. He is certified in advanced bioidentical hormone replacement.

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Misinformation That May Be Costing Women Their Lives - Jewish Link of New Jersey

Reasons why you’re gaining weight out of nowhere – The Advocate

Reasons why you're gaining weight out of nowhere

Its understandable when you gain a few pounds after a vacation or if you break your ankle and spend six weeks propped on the couch binge watching cooking shows (and the sweets to go with them).

But when you can't zip your jeans for no reason at all you swear youre not eating any more or exercising any less it can feel like theres some dark magic at play. You may find yourself standing on the bathroom scale, screaming into the void:

Most likely, theres something in your life thats shifted just enough to make a difference, but not so much that youd notice, says Dr. Alexandra Sowa, an obesity specialist and clinical instructor of medicine at NYU Langone Health. I see this all the time. You may not step on the scale for a while, and you feel like you havent changed anything, and all of a sudden you go to the doctors office and notice youve gained 10 or 20 pounds, she says.

But that doesnt mean its your destiny to go up another size every year. Here are some of the most likely reasons for unexplained weight gain, and how to stop it in its tracks.

If youve been battling weight issues for a while and none of your efforts are moving the needle, make an appointment with your primary care doctor or a weight-management physician, who can assess you for insulin resistance or prediabetes. Your doctor can also test you for hypothyroidism, in which your thyroid gland doesnt produce enough hormone, slowing down your metabolism and potentially leading to weight gain.

Insulin is the hormone that signals the body to pull glucose out of the bloodstream and store it in the muscles, liver and fat, explains Dr. Tirissa Reid, an obesity medicine specialist at Columbia University Medical Center and Diplomate of the American Board of Obesity Medicine. But when youre overweight, the cells dont recognize the insulin as well, so the pancreas has to pump out more and more sometimes two or three times the normal amount until the cells respond. This is also common in women who have polycystic ovary syndrom, a condition in which the egg follicles in the ovaries bunch together to form cysts.

These high insulin levels keep the body in storage mode and make weight loss more difficult, says Dr. Reid. The beginning of this road is insulin resistance when your pancreas is working overtime, but blood sugar levels are still normal. All that extra work wears out the pancreas until it can barely do the job of keeping the blood sugar in normal range. Left unchecked, insulin resistance can lead to prediabetes, in which blood-sugar levels are slightly elevated; if thats not treated, you can develop full-blown type-2 diabetes.

What you can do: The most effective way to reverse this trend is to eat a diet low in refined carbs and added sugars, and to become more physically active, since muscles respond better to insulin after exercise, says Dr. Reid.

She recommends either investing in a fitness tracker or simply using the one that comes with your phone. People hear you need 10,000 steps each day, which sounds intimidating, but you can also use it just to see where youre at and make doable increases, Dr. Reid says. If youre at 2,000 steps, try to go up to 2,500 a day next week and continue to increase. Swapping to foods with a lower glycemic index (GI) which means theyre digested more slowly, keeping blood-sugar levels steady is also important for controlling your insulin levels. Dr. Sowa recommends these lower-GI food swaps: riced cauliflower instead of white rice; zucchini spirals or shirataki noodles (made from plant fiber) instead of pasta; and pumpernickel or stone-ground whole wheat bread instead of white bread or bagels.

If youre up at night worrying about your aging parents or your kids, this can affect your metabolism. Stress and lack of sleep can cause a cascade of hormonal changes that change your metabolism and affect your sense of hunger and fullness, Dr. Sowa explains.

Stress pumps up the hormones ghrelin and cortisol, which increase your appetite and can make you crave carbs; at the same time, it dials down the hormone leptin, which helps you feel full. Not surprisingly, a 2018 Swedish study of 3,872 women over 20 years found the more stressed you are by work, the more likely you are to gain weight. Stress also affects your ability to get a good nights sleep, and we know that lack of sleep can also throw off your metabolism rates and hunger cues.

What you can do: You can manage your stress by downloading an app such that helps you work toward personal goals such as thinking positively and decreasing anxiety by sending you meditations and visualizations to do throughout the day. To sleep more soundly, you already know you should put down your phone, computer and iPad an hour before bedtime, but research shows that shutting out all light including that sliver of moon through your window can help with both sleep and metabolism. A study at Northwestern University Feinberg School of Medicine found that after subjects spent just one night of sleeping in a room with dim light, insulin levels the next morning were significantly higher than those who slept in complete darkness, potentially affecting metabolism rates. So consider investing in some good blackout curtains.

Were not 100% sure why, but its believed that histamines, chemicals produced by your immune system to fight allergens, have a role in appetite control, says Dr. Reid. That means that antihistamines may cause you to eat more, she says. A study from Yale University confirmed that there is a correlation between regular prescription antihistamine use and obesity. Dr. Reid points out that some antihistamines such as Benadryl also cause drowsiness, which could make you less apt to exercise.

What you can do: If you suffer from seasonal allergies and are constantly taking antihistamines, talk to your allergist about alternative treatments such as nasal steroid sprays, nasal antihistamines (which have less absorption into the bloodstream, and therefore less effect on hunger), leukotriene inhibitors such as Singulair or allergy shots, suggests Dr. Jeffrey Demain, founder of the Allergy Asthma and Immunology Center of Alaska. He also says that managing your environment using a HEPA filter, washing your sheets frequently in hot water and keeping pets out of your bedroom can help reduce the need for allergy medication. While youre at it, do an inventory of any prescription medications youre taking that are known to cause weight gain (including certain antidepressants, beta blockers, corticosteroids and the birth control shot) and discuss with your doctor if there are equally effective alternatives that dont affect weight, says Dr. Reid.

Anyone whos ever sat in a vinyl booth staring down a big bowl of pasta knows that portion sizes in America are large. But research from the University of Liverpool published in 2018 found after being served large-size meals outside the home, people tend to serve themselves larger portions up to a week later, meaning supersizing appears to be normalized, says Dr. Lisa R. Young, author of Finally Full, Finally Slim.

Here's what to do: First, Young suggests you spend a few days getting a reality check on how much food youre actually eating at each meal. When you pour the cereal in the bowl in the morning, pour it back into a measuring cup. What you thought was one cup might actually be three cups, especially if youre using a large bowl, she says.

Also, instead of relying on a government agency (or the chef at your favorite restaurant) at to tell you how much to eat, learn to listen to your own body, says Young. Serve yourself just one modest portion on a small plate, and when youre done, wait 20 minutes, she says. It takes that long for the hormones in your belly to reach your brain and tell it youre full. If you get to 20 minutes and your stomach is grumbling, have a few more bites.

Lets say you switched jobs recently, and dinner is now at 9 p.m. instead of 6:30. Or your new habit of streaming Neflix until the wee hours also involves snacking well past midnight. Even if youre not eating more, per se, this change might account for the extra pounds.

Theres a delicate balance between your circadian rhythm (the way your body and brain respond to the daily cues of daylight and darkness) and your calorie intake. That can mean that same sandwich that you eat at lunchtime may actually cause more of a weight gain when eaten at night. A 2017 study at Brigham and Womens Hospital found when college students ate food closer to their bedtime and therefore closer to when the sleep-inducing hormone melatonin was released they had higher percentages of body fat and a higher body-mass index. The researchers theorize this is because the amount of energy your body uses to digest and metabolize food drops as your inner clock tells it to get ready to snooze.

What you can do: There are a few life hacks to keep the late-night snacking to a minimum. Dr. Sowa suggests you commit to writing down every bite you eat after dinner: Whether its on a sticky pad or on an app, keeping track of what youre eating, how much youre eating and how youre feeling when you eat it will hold you accountable for the calories, and it will also help you figure out if youre truly hungry or just bored, she says. She also suggests capping off your evening meal with a brain-and-heart-healthy tablespoon of fish oil. Its a healthy fat that coats your stomach and makes you feel less hungry later, she says.

Each birthday you celebrate brings on one undeniable change: your basal resting metabolism (the rate at which your body at rest burns the energy you take in from food) slows down. Its not a dramatic drop, says Dr. Cheskin. But as you age, youre probably also getting less active and more tired, and your body tends to lose muscle mass, which burns calories more efficiently than fat. So even if youre eating the exact same amount of food as you did when you were younger, your body is simply not burning it off as effectively as it did during the glory days of your 20s.

Here's what to do: You can only budge your BMR a little, but there are a few things you can do to make the math work in your favor. The first is to build up your calorie-burning muscle, says fitness expert Dr. Michele Olson, a professor of sports science and physical education at Huntingdon College. Keep up cardio three times a week for 30 minutes, but add challenging weight training on top of that, she says.

Another metabolism-boosting strategy: Replace some of the carbohydrates in your diet with proteins, which take more energy to digest, therefore burning off more calories through diet-induced thermogenesis, as well as making you feel fuller for longer. Dr. Sowa suggests you eat about 100 grams of protein over the course of the day, filling your plate with lean chicken, fish, shrimp or plant-based proteins such as garbanzo beans, tempeh and edamame, to give your meals more metabolism bang for your buck. This may only add up to a weight loss of a few pounds per year, but combined with exercise, the cumulative effect can be significant, says Dr. Sowa.

Read more here:
Reasons why you're gaining weight out of nowhere - The Advocate

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