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4th Annual genetics and genomics: advances across the lifespan September 15 Cleveland, OH

Breakthroughs in cognitive neurological disorders September 16 Cleveland, OH

Fundamental to advanced echocardiography September 1618 Cleveland, OH

Cleveland Clinic Digestive Disease Institute boot camp for the GI boards September 1619 Las Vegas, NV

Heart rhythm care in the 21st century: allied professional regional conference September 17 Cleveland, OH

Cleveland Clinic Fairview Hospital epilepsy update September 17 Cleveland, OH

2016 Primary care women's health: essentials and beyond September 22 Beachwood, OH

Women in healthcare forum: focus on resiliency September 23 Beachwood, OH, and Weston, FL

8th Annual practical management of acute stroke: fast and furious stroke care September 23 Independence, OH

Cleveland Clinic epilepsy update and review course September 2527 Cleveland, OH

11th Annual obesity summit September 2930 Cleveland, OH

Current management of prevalent cardiovascular diseases October 7 New York, NY

2016 Nephrology update October 2022 Cleveland, OH

18th Annual brain tumor update and 7th annual international symposium on long-term control of metastases to the brain and spineOctober 2223 Las Vegas, NV

3rd Annual multidisciplinary colorectal oncology course October 28 Cleveland, OH

5th Annual primary care evidence-based medicine update October 2829 Beachwood, OH

11th Annual Nemacolin international asthma conference October 2830 Farmington, PA

Exploring the functional medicine model: a case-based approach November 4 Cleveland, OH

52nd Annual gastroenterology update November 5 Warrensville Heights, OH

Advancing neurological therapeutics November 5 Las Vegas, NV

16th Annual multidisciplinary genitourinary oncology course November 10 Cleveland, OH

5th Annual comprehensive neurotoxin course for neurological conditions November 11 Cleveland, OH

2nd Cleveland Clinic beta cell therapy symposium: advances in management of diabetes November 1112 Cleveland, OH

Clinical management of MDS/MPN: a mountain of evidence for treatment selection in MDS/MPNDecember 2 San Diego, CA

Dr. Roizen's preventive, integrative, and lifestyle medicine conference December 24 Las Vegas, NV

15th Annual liver update: a report from the American Association for the Study of Liver Disease annual meeting December 9 Beachwood, OH

Clinic seminars: dermatology December 9 Beachwood, OH

19th Annual pain management symposium February 48 Orlando, FL

Digestive Disease Institute week 2017 February 1419 Boca Raton, FL

6th Annual gastroenterology and hepatology symposium February 1618 Boca Raton, FL

5th Annual basic and clinical immunology for the busy clinician: an immunology boot camp February 1718 Las Vegas, NV

Breakthroughs in neuro-cognitive disorders February 25 Fort Lauderdale, FL

Valve disease and diastology summit March 46 Miami Beach, FL

2017 Multidisciplinary head and neck cancer update March 1011 Orlando, FL

Primary vasculitides: best practices and future advances April 5 Cleveland, OH

Biologic therapies VII summit: precision medicine in the biologic era April 68 Cleveland, OH

Cleveland breast cancer symposium 2017 May 11-12 Cleveland, OH

22nd Annual diabetes day May 12 Cleveland, OH

29th Annual intensive review of internal medicine June 49 Cleveland, OH

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NATESTO (testosterone) Nasal Gel CIII | Prescriber Site

On each valid NATESTO prescription or refill, maximum savings is $150 per use, up to 13 uses. Patient is responsible for any balance remaining, and for reporting receipt of this coupon benefit to any insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using the coupon, as may be required. Patient, pharmacist, and prescriber agree not to seek reimbursement for all or any part of the benefit received by the patient through this offer.

Offer only valid for male patients over age 18 who have private health insurance. Offer not valid for uninsured patients or for patients eligible for Medicaid, Medicare, TRICARE, Veterans Affairs or any other state or federal healthcare program (including state prescription drug programs). Offer good only in USA and void where prohibited by law, taxed, or restricted. Aytu Pharmaceuticals reserves the right to rescind, revoke, or amend this offer without notice. Card is limited to one per person, is not transferable, and cannot be reproduced. This card is not health insurance.

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Talk to Nurse Rita – Health, Nursing & Clinic Matters

Lime, bearing the scientific name Citrus Aurantifolia, has been used for ages in the treatment of various ailments.The first fruit that comes to mind in terms of medicinal uses is the reliable lime. This sour citrus fruit can do what many advanced medicines cannot. Lime is consumed throughout the world in the form of sorbet, beverages, refreshing cocktails, pickles, jams, jellies, snacks, candies, sugar boiled confections and in cooking. The oil extracted from its peel or skin is extensively used in soft drink concentrates, body oils, cosmetic products, hair oils, toothpastes, toilet and beauty soaps, disinfectants, mouth washes, deodorants and innumerable other products. There are many varieties of lime found all over the world, particularly in the tropical and the Mediterranean climates. Lets take a look at the benefits and medicinal uses of lime,am sure you would be amazed. Scurvy: Lime is very well-known as a cure for scurvy, the disease which is caused from a deficiency of vitamin-C. It is characterized by frequent infections that show as normal cold symptoms, cracked lips and lip corners, ulcers on the tongue and in the mouth. You can also spot scurvy from spongy, swollen and bleeding gums. Since its cause is a deficiency of vitamin-C, its remedy is none other than vitamin-C, and lime is full of this this essential vitamin. In the past, soldiers and sailors were given lime to keep them safe from scurvy, which was a horrible and potentially fatal disease back then. Even now, it is distributed among the workers working in polluted environments like furnaces, painting shops, heat treatments, cement factories, mines, and other dangerous work environments to protect them from scurvy. Skin Care: Lime juice and its natural oils are very beneficial for skin when consumed orally or applied externally. It rejuvenates the skin, keeps it shining, protects it from infections and reduces body odor due to the presence of a large amount of vitamin-C and Flavonoids. Those are both class-1 anti oxidants, and have antibiotic and disinfectant properties. When applied externally on skin, its acids scrub out the dead cells, cures dandruff, rashes, and bruises. It can also be used to create a refreshing bathing experience if its juice or oil is mixed into your bathing water.

Digestion: Lime has an irresistible scent which causes your mouth to water and this actually aids primary digestion (the digestive saliva floods your mouth even before you taste it). The natural acidity in lime does the rest. While they break down of the macro molecules of the food, the Flavonoids, the compounds found in the fragrant oils extracted from lime, stimulate the digestive system and increase secretion of digestive juices, bile and acids. This flood of flavonoids also stimulate the peristaltic motion. This is the reason behind lemon pickle with lunch and dinner being a traditional practice in India and various neighboring countries in that region.

Constipation: Primarily, the ample amount of acids present in lime helps clear the excretory system by washing and cleaning off the tracts, just as some acids are used to clean floors and toilets. The roughage in lime is also helpful in easing constipation, but the most beneficial element is the high acidity. An overdose of lime juice with salt also acts as an excellent purgative without any side effects, thereby providing relief from constipation.

Diabetes: According to the American Diabetes Association, limes and other citrus fruits are considered a diabetes super food for a number of reasons. Mainly, the high levels of soluble fiber found in limes make it an ideal dietary aid to help regulate the bodys absorption of sugar into the bloodstream, reducing the occurrence of blood sugar spikes that are a serious risk to to diabetic patients. Also, limes and other citrus fruits have a low glycemic index, which means that they will not cause unexpected spikes in glucose levels, in addition to the benefits of soluble fibers effect.

Heart Disease: That same soluble fiber which can help diabetics maintain their blood sugar levels can also lower blood pressure and eliminate the presence of LDL cholesterol (bad cholesterol). Furthermore, soluble fiber can cut down on inflammation of the blood vessels, which is a known preventative measure against heart disease, heart attacks, and strokes.

Peptic Ulcer:In addition to vitamin-C, lime contains special compounds called Flavonoids (Limonoids such as Limonin Glucoside) which have antioxidant, anti-carcinogenic, antibiotic and detoxifying properties that stimulate the healing process of peptic and oral ulcers.

Respiratory Disorders: The flavonoid-rich oil that is extracted from limes is extensively used in anti-congestive medicines such as balms, vaporizers, and inhalers due to the presence of Kaempferol. Just scratching the peel of a lime and inhaling it gives immediate relief for congestion and nausea.

Arthritis: One of the many causes of arthritis is an excess of uric acid that builds up in the body. Uric acid is one of the waste products that normal urination will clear out of the body, but unfortunately, when too much builds up, it can make the pain and inflammation from arthritis even worse. The citric acid found in citrus fruits like limes is a solvent in which uric acid can dissolve, increasing the amounts that are eliminated in the urine. Citrus fruits in general have anti-inflammatory properties, and can be used for a number of inflammation issues.

Eye Care: Vitamin-C again! Its anti oxidant properties protect eyes from aging and macular degeneration. On top of that, flavonoids help protect them from infections.

Fever: If someone is suffering from a fever, limes and lime juice can be of great importance. Citrus fruits in general have fever-reducing qualities, and if the fever is very high, the patients diet should be restricted to lemon juice and water. However, if the fever is mild to moderate, other fruit juices, particularly citrus juices like lime juice, can be administered in order to bring the fever back a manageable level. Vitamin-C, found in high concentrations in citrus fruits, naturally lowers the temperature of the body.

Gout: There are two main causes of gout. The first source is the accumulation of free radicals in the body, and the second is accumulation of toxins in the body, primarily uric acid. Limes can help prevent both of these causes. It is a wonderful source of antioxidants & detoxifiers (vitamin-C & Flavonoids) which reduce the number of free radicals as well as detoxifying the body.

Gums: The root cause of gum problems is a deficiency of vitamin-C (Scurvy, which gives bleeding and spongy gums) and microbial growth. Sometimes, the ulcers come from physical trauma. In all of these situations, limes can help. Its vitamin-C cures scurvy, Flavonoids inhibit microbial growth and potassium and Flavonoids help heal ulcers and wounds.

Piles: Since lime helps heal ulcers and wounds in the digestive system and excretory system while providing relief from constipation, it eradicates all the root causes of piles. Piles are a different term for hemorrhoids, an uncomfortable condition that occurs in the anal region and can result in bleeding and discomfort both during excretion and general activity. It can also lead to certain forms of cancer, and limes can help prevent their formation or recurrence.

Cholera: Although it has disappeared in many parts of the world, cholera is still a dangerous and deadly disease in some places on the planet, and luckily, limes and other citrus fruits can help defend against this often fatal condition. The lime juice, when added to potentially infected water, proved to be a very effective disinfectant, and even when it was consumed regularly after someone had been exposed to cholera-infected water, fatalities were reduced. Numerous studies were done on this application of lime juice, particularly following the horrible outbreak of cholera in Guinea-Bissau in 1994.

Weight Loss: A glass of warm water with a full limes worth of juice in it is an excellent weight reducer as well as a brilliant refresher and antioxidant drink. The citric acid present in lime is an excellent fat burner. You can consume two glasses a day and see legitimate and remarkable results within a week.

Urinary Disorders: The high potassium content of limes is very effective in removal of the toxic substances and the precipitates which get deposited in kidneys and the urinary bladder. The disinfectant properties of limes also help cure infections in the urinary system. Furthermore, it stops prostrate growth (very common in males above 40) and clears blockage of urine that can come from calcium deposits in the urinary tract.

Other Benefits: It is a good appetizer and digestive. It can help to cure rheumatism, prostate and colon cancer, cholera, arteriosclerosis, fatigue and even high fevers (contrary to popular belief). The best part of it is that it has no negative side effects!


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Human chorionic gonadotropin – Wikipedia, the free …

Human chorionic gonadotropin (hCG) is a hormone produced by the embryo after implantation.[1][2] The presence of hCG is detected in some pregnancy tests (HCG pregnancy strip tests). Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant can lead to a cancer diagnosis and, if high enough, paraneoplastic syndromes. However, it is not known whether this production is a contributing cause or an effect of carcinogenesis. The pituitary analog of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages.[1][3]

Regarding endogenous forms of hCG, there are various ways to categorize and measure them, including total hCG, C-terminal peptide total hCG, intact hCG, free -subunit hCG, -core fragment hCG, hyperglycosylated hCG, nicked hCG, alpha hCG, and pituitary hCG. Regarding pharmaceutical preparations of hCG from animal or synthetic sources, there are many gonadotropin preparations, some of which are medically justified and others of which are of a quack nature. As of December 6, 2011[update], the United States FDA has prohibited the sale of "homeopathic" and over-the-counter hCG diet products and declared them fraudulent and illegal.[4][5][6]

Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 25.7 kDa.[7]

It is heterodimeric, with an (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and (beta) subunit that is unique to hCG.

The two subunits create a small hydrophobic core surrounded by a high surface area-to-volume ratio: 2.8 times that of a sphere. The vast majority of the outer amino acids are hydrophilic.[7]

Human chorionic gonadotropin interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to secrete the hormone progesterone during the first trimester. Progesterone enriches the uterus with a thick lining of blood vessels and capillaries so that it can sustain the growing fetus[citation needed].

Due to its highly negative charge, hCG may repel the immune cells of the mother, protecting the fetus during the first trimester[citation needed]. It has also been hypothesized that hCG may be a placental link for the development of local maternal immunotolerance[citation needed]. For example, hCG-treated endometrial cells induce an increase in T cell apoptosis (dissolution of T cells). These results suggest that hCG may be a link in the development of peritrophoblastic immune tolerance, and may facilitate the trophoblast invasion, which is known to expedite fetal development in the endometrium.[10] It has also been suggested that hCG levels are linked to the severity of morning sickness or Hyperemesis gravidarum in pregnant women.[11]

Because of its similarity to LH, hCG can also be used clinically to induce ovulation in the ovaries as well as testosterone production in the testes. As the most abundant biological source is women who are presently pregnant, some organizations collect urine from pregnant women to extract hCG for use in fertility treatment.[12][13]

Human chorionic gonadotropin also plays a role in cellular differentiation/proliferation and may activate apoptosis.[14]

Naturally, it is produced in the human placenta by the syncytiotrophoblast.

Like other gonadotropins, it can be extracted from the urine of pregnant women or produced from cultures of genetically modified cells using recombinant DNA technology.

In Pregnyl, Follutein, Profasi, Choragon and Novarel, it is extracted from the urine of pregnant women. In Ovidrel, it is produced with recombinant DNA technology.[15]

Regarding endogenous forms of hCG, there are various ways to categorize and measure them, including total hCG, C-terminal peptide total hCG, intact hCG, free -subunit hCG, -core fragment hCG, hyperglycosylated hCG, nicked hCG, alpha hCG, and pituitary hCG.

Regarding pharmaceutical preparations of hCG from animal or synthetic sources, there are many gonadotropin preparations, some of which are medically justified and others of which are of a quack nature.

Blood or urine tests measure hCG. These can be pregnancy tests. hCG-positive indicates an implanted blastocyst and mammalian embryogenesis. These can be done to diagnose and monitor germ cell tumors and gestational trophoblastic diseases.

Concentrations are commonly reported in thousandth international units per milliliter (mIU/ml). The international unit of hCG was originally established in 1938 and has been redefined in 1964 and in 1980.[16] At the present time, 1 international unit is equal to approximately 2.351012 moles,[17] or about 6108 grams.[18]

Most tests employ a monoclonal antibody, which is specific to the -subunit of hCG (-hCG). This procedure is employed to ensure that tests do not make false positives by confusing hCG with LH and FSH. (The latter two are always present at varying levels in the body, whereas the presence of hCG almost always indicates pregnancy.)

Many hCG immunoassays are based on the sandwich principle, which uses antibodies to hCG labeled with an enzyme or a conventional or luminescent dye. Pregnancy urine dipstick tests are based on the lateral flow technique.

The following is a list of serum hCG levels. (LMP is the last menstrual period dated from the first day of your last period.) The levels grow exponentially after conception and implantation.

The ability to quantitate the hCG level is useful in the monitoring germ cell and trophoblastic tumors, follow-up care after miscarriage, and in diagnosis of and follow-up care after treatment of ectopic pregnancy. The lack of a visible fetus on vaginal ultrasound after the hCG levels have reached 1500 mIU/ml is strongly indicative of an ectopic pregnancy.[21] Still, even an hCG over 2000 IU/l does not necessarily exclude the presence of a viable intrauterine pregnancy in such cases.[22]

As pregnancy tests, quantitative blood tests and the most sensitive urine tests usually detect hCG between 6 and 12 days after ovulation.[23] However, it must be taken into account that total hCG levels may vary in a very wide range within the first 4 weeks of gestation, leading to false results during this period.[24] A rise of 35% over 48 hours is proposed as the minimal rise consistent with a viable intrauterine pregnancy.[22]

Gestational trophoblastic disease like hydatidiform moles ("molar pregnancy") or choriocarcinoma may produce high levels of hCG (due to the presence of syncytialtrophoblasts- part of the villi that make up the placenta) despite the absence of an embryo. This, as well as several other conditions, can lead to elevated hCG readings in the absence of pregnancy.

hCG levels are also a component of the triple test, a screening test for certain fetal chromosomal abnormalities/birth defects.

A study of 32 normal pregnancies came to the result a gestational sac of 13mm was detected at a mean hCG level of 1150 UI/l (range 800-1500), a yolk sac was detected at a mean level of 6000 UI/l (range 4500-7500) and fetal heartbeat was visible at a mean hCG level of 10,000 UI/l (range 8650-12,200).[25]

Human chorionic gonadotropin can be used as a tumor marker,[26] as its subunit is secreted by some cancers including seminoma, choriocarcinoma, germ cell tumors, hydatidiform mole formation, teratoma with elements of choriocarcinoma, and islet cell tumor. For this reason a positive result in males can be a test for testicular cancer. The normal range for men is between 0-5 mIU/mL. Combined with alpha-fetoprotein, -HCG is an excellent tumor marker for the monitoring of germ cell tumors.[citation needed]

Human chorionic gonadotropin is extensively used parenterally for final maturation induction in lieu of luteinizing hormone. In the presence of one or more mature ovarian follicles, ovulation can be triggered by the administration of HCG. As ovulation will happen between 38 and 40 hours after a single HCG injection,[27] procedures can be scheduled to take advantage of this time sequence,[28] such as intrauterine insemination or sexual intercourse. Also, patients that undergo IVF, in general, receive HCG to trigger the ovulation process, but have an oocyte retrieval performed at about 34 to 36 hours after injection by, a few hours before the eggs actually would be released from the ovary.

As HCG supports the corpus luteum, administration of HCG is used in certain circumstances to enhance the production of progesterone.

In the male, HCG injections are used to stimulate the Leydig cells to synthesize testosterone. The intratesticular testosterone is necessary for spermatogenesis from the sertoli cells. Typical uses for HCG in men include hypogonadism and fertility treatment.

Several vaccines against human chorionic gonadotropin (hCG) for the prevention of pregnancy are currently in clinical trials.[29]

In the case of female patients who want to be treated with HCG Pregnyl:[30] a) Since infertile female patients who undergo medically assisted reproduction (especially those who need in vitro fertilization), are known to often be suffering from tubal abnormalities, after a treatment with this drug they might experience many more ectopic pregnancies. This is why early ultrasound confirmation at the beginning of a pregnancy (to see whether the pregnancy is intrauterine or not) is crucial. - Pregnancies that have occurred after a treatment with this medicine are submitted to a higher risk of multiplets. - Female patients who have thrombosis, severe obesity or thrombophilia should not be prescribed this medicine as they have a higher risk of arterial or venous thromboembolic events after or during a treatment with HCG Pregnyl. b)Female patients who have been treated with this medicine are usually more prone to pregnancy losses.

In the case of male patients: A prolonged treatment with HCG Pregnyl is known to regularly lead to increased production of androgen. Therefore: Patients who are suffering from overt or latent cardiac failure, hypertension, renal dysfunction, migraines or epilepsy might not be allowed to start using this medicine or may require a lower dose of HCG Pregnyl. Also this medicine should be used with extreme caution in the treatment of prepubescent teenagers in order to reduce the risk of precocious sexual development or premature epiphyseal closure. This type of patients' skeletal maturation should be closely and regularly monitored.

Both male and female patients who have the following medical conditions must not start a treatment with HCG Pregnyl: (1) Hypersensitivity to this medicine or to any of its main ingredients. (2) Known or possible androgen-dependent tumors for example male breast carcinoma or prostatic carcinoma.

In the world of performance-enhancing drugs, HCG is increasingly used in combination with various anabolic androgenic steroid (AAS) cycles. As a result, HCG is included in some sports' illegal drug lists.

When exogenous AAS are put into the male body, natural negative-feedback loops cause the body to shut down its own production of testosterone via shutdown of the hypothalamic-pituitary-gonadal axis (HPGA). This causes testicular atrophy, among other things. HCG is commonly used during and after steroid cycles to maintain and restore testicular size as well as normal testosterone production.[31]

High levels of AASs, that mimic the body's natural testosterone, trigger the hypothalamus to shut down its production of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Without GnRH, the pituitary gland stops releasing luteinizing hormone (LH). LH normally travels from the pituitary via the blood stream to the testes, where it triggers the production and release of testosterone. Without LH, the testes shut down their production of testosterone.[32] In males, HCG helps restore and maintain testosterone production in the testes by mimicking LH and triggering the production and release of testosterone.

If HCG is used for too long and in too high a dose, the resulting rise in natural testosterone would eventually inhibit its own production via negative feedback on the hypothalamus and pituitary gland.[citation needed]

Professional athletes who have tested positive for HCG have been temporarily banned from their sport, including a 50-game ban from MLB for Manny Ramirez in 2009[33] and a 4-game ban from the NFL for Brian Cushing for a positive urine test for HCG.Mixed Martial Arts fighter Dennis Siver was fined $19,800 and suspended 9 months for being tested positive after his bout at UFC 168.[35]

British endocrinologist Albert T. W. Simeons proposed HCG as an adjunct to an ultra-low-calorie weight-loss diet (fewer than 500 calories).[36] Simeons, while studying pregnant women in India on a calorie-deficient diet, and "fat boys" with pituitary problems (Frlich's syndrome) treated with low-dose HCG, observed that both lost fat rather than lean (muscle) tissue.[36] He reasoned that HCG must be programming the hypothalamus to do this in the former cases in order to protect the developing fetus by promoting mobilization and consumption of abnormal, excessive adipose deposits. Simeons in 1954 published a book entitled Pounds and Inches, designed to combat obesity. Simeons, practicing at Salvator Mundi International Hospital in Rome, Italy, recommended low-dose daily HCG injections (125IU) in combination with a customized ultra-low-calorie (500 cal/day, high-protein, low-carbohydrate/fat) diet, which was supposed to result in a loss of adipose tissue without loss of lean tissue.[36]

Simeons' results were not reproduced by other researchers and in 1976 in response to complaints the FDA required Simeons and others to include the following disclaimer on all advertisements:[37]

These weight reduction treatments include the injection of HCG, a drug which has not been approved by the Food and Drug Administration as safe and effective in the treatment of obesity or weight control. There is no substantial evidence that HCG increases weight loss beyond that resulting from caloric restriction, that it causes a more attractive or "normal" distribution of fat, or that it decreases the hunger and discomfort associated with calorie-restrictive diets.

1976 FDA-mandated disclaimer for HCG diet advertisements

There was a resurgence of interest in the "HCG diet" following promotion by Kevin Trudeau who was later banned from making HCG diet weight-loss claims by the U.S. Federal Trade Commission and eventually jailed over such claims.[38]

While not specifically cited here, review studies refuting the HCG diet have been published in the Journal of the American Medical Association and the American Journal of Clinical Nutrition,[39] concluded that HCG is not more effective as a weight-loss aid than dietary restriction alone.[40]

A meta analysis found that studies supporting HCG for weight loss were of poor methodological quality and concluded that "there is no scientific evidence that HCG is effective in the treatment of obesity; it does not bring about weight-loss or fat-redistribution, nor does it reduce hunger or induce a feeling of well-being".[41]

There is no scientific evidence that HCG is effective in the treatment of obesity. The meta-analysis found insufficient evidence supporting the claims that HCG is effective in altering fat-distribution, hunger reduction or in inducing a feeling of well-being. The authors stated the use of HCG should be regarded as an inappropriate therapy for weight reduction In the authors opinion, Pharmacists and physicians should be alert on the use of HCG for Simeons therapy. The results of this meta-analysis support a firm standpoint against this improper indication. Restraints on physicians practicing this therapy can be based on our findings.

According to the American Society of Bariatric Physicians, no new clinical trials have been published since the definitive 1995 meta-analysis.[42]

The scientific consensus is that any weight loss reported by individuals on an "HCG diet" may be attributed entirely to the fact that such diets prescribe calorie intake of between 500 and 1,000 calories per day, substantially below recommended levels for an adult, to the point that this may risk health effects associated with malnutrition.[43]

Controversy about, and shortages[44] of, injected HCG for weight loss have led to substantial Internet promotion of "homeopathic HCG" for weight control. The ingredients in these products are often obscure, but if prepared from true HCG via homeopathic dilution, they contain either no HCG at all or only trace amounts. Moreover, it is highly unlikely that oral HCG is bioavailable due to the fact that digestive protease enzymes and hepatic metabolism renders peptide-based molecules (such as insulin and human growth hormone) biologically inert. HCG can likely only enter the bloodstream through injection.

The United States Food and Drug Administration has stated that over-the-counter products containing HCG are fraudulent and ineffective for weight loss. They are also not protected as homeopathic drugs and have been deemed illegal substances.[45][46] HCG itself is classified as a prescription drug in the United States and it has not been approved for over-the-counter sales by the FDA as a weight loss product or for any other purposes, and therefore neither HCG in its pure form nor any preparations containing HCG may be sold legally in the country except by prescription.[4] In December 2011, FDA and FTC started to take actions to pull unapproved HCG products from the market.[4] In the aftermath, some suppliers started to switch to "hormone-free" versions of their weight loss products, where the hormone is replaced with an unproven mixture of free amino acids[47] or where radionics is used to transfer the "energy" to the final product.

In order to induce a stronger immune response, some versions of human chorionic gonadotropin based anti-fertility vaccines were designed as conjugates of the subunit of HCG covalently linked to tetanus toxoid.[29][48] It has been alleged that a non-conguated tetanus vaccine used in developing countries is laced with a human chorionic gonadotropin based anti-fertility drug[49] and is distributed as a means of mass sterilization.[50] This charge has been vigorously denied by the World Health Organization (WHO) and UNICEF.[51] Others have argued that a hCG laced vaccine could not be used for sterilization since the effects of the anti-fertility vaccines are reversible (requiring booster doses to maintain immunity) and a non-conjugated vaccine is likely to be ineffective.[52][53] Finally, independent testing of the tetanus vaccine by Kenyas health authorities has revealed no traces of the human chorionic gonadotropin hormone.[54]

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melatonin hormone – University of Maryland Medical Center

Uses Insomnia

Studies suggest that melatonin supplements may help people with disrupted circadian rhythms (such as people with jet lag or those who work the night shift), and those with low melatonin levels (such as some seniors and people with schizophrenia) to sleep better. A review of the scientific literature suggests that melatonin supplements may help prevent jet lag, particularly in people who cross 5 or more time zones.

A few clinical studies suggest that, when taken for short periods of time (days to weeks), melatonin is more effective than a placebo in reducing the time it takes to fall asleep, increasing the number of sleeping hours, and boosting daytime alertness. It is not clear how well melatonin works, however. Some studies suggest that it only reduces the amount of time to fall asleep by a few minutes.

Several human studies have measured the effects of melatonin supplements on sleep in healthy people. A wide range of doses has been used, often taken by mouth 30 to 60 minutes prior to sleep time. Results have been mixed. Some evidence suggests that melatonin may work best for people over 55 who have insomnia. One study of 334 people aged 55 and older found that sustained-release melatonin seemed to help people with primary insomnia fall asleep faster, sleep better, be more alert in the morning, and improve quality of life in people with primary insomnia.

Several studies show melatonin has cardioprotective properties, including antioxidant and anti-inflammatory effects. Research also suggests that melatonin may help lower blood pressure levels and improve cholesterol profiles. More research is needed.

Melatonin supplements may improve sleep problems associated with menopause. Other studies suggest it may help restore quality of life and prevent bone loss among perimenopausal women. However, it does not appear to relieve other symptoms of menopause, such as hot flashes. Peri- or postmenopausal women who use melatonin supplements should do so only for a short period of time since long-term effects are not known.

Some research suggests that melatonin may help elderly people with insomnia who are tapering off or stopping benzodiazepines such as diazepam (Valium), alprazolam (Xanax), or lorazepam (Ativan). Taking controlled-release melatonin improved sleep quality in those stopping benzodiazepine use. More research is needed. You should never combine melatonin with sedative medications unless you are under the strict supervision of a health care provider.

Several studies suggest that low melatonin levels may be associated with breast cancer risk. For example, women with breast cancer tend to have lower levels of melatonin than those without the disease. Laboratory experiments have found that low levels of melatonin stimulate the growth of certain types of breast cancer cells, while adding melatonin to these cells slows their growth. Preliminary evidence also suggests that melatonin may strengthen the effects of some chemotherapy drugs used to treat breast cancer. In a study that included a small number of women with breast cancer, melatonin (given 7 days before beginning chemotherapy) prevented the lowering of platelets in the blood. This is a common complication of chemotherapy that can lead to bleeding.

In another small study of women who were taking tamoxifen for breast cancer but seeing no improvement, adding melatonin caused tumors to modestly shrink in more than 28% of the women. Women with breast cancer should ask their doctors before taking melatonin.

Studies show that men with prostate cancer have lower melatonin levels than men without the disease. In test tube studies, melatonin blocks the growth of prostate cancer cells. In one small-scale study, melatonin, combined with conventional medical treatment, improved survival rates in 9 out of 14 men with metastatic prostate cancer. Interestingly, since meditation may cause melatonin levels to rise it appears to be a valuable addition to the treatment of prostate cancer. More research is needed before doctors can make recommendations in this area. Men with prostate cancer should talk to their doctor before taking medication.

Some evidence suggests that melatonin may help promote sleep in children with ADHD or autism, although it does not seem to improve the behavioral symptoms of ADHD or autism.

A randomized, placebo-controlled study found that people with fibromyalgia experienced a significant reduction in their symptoms when they took a melatonin supplement either alone or in conjunction with fluoxetine (Prozac). Other studies suggest that melatonin may play a role in other painful conditions, such as migraines. People with chronic pain should speak to their physicians before using melatonin as it can interact with some medications.

Acuna-Castroviejo D, Escames G, Rodriguez MI, Lopez LC. Melatonin role in the mitochondrial function. Front Biosci. 2007;12:947-63.

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Barcelo E. melatonin and mammary cancer: a short review. Endocrine-Related Cancer. 2003;10:153-9.

Bazil CW, Short D, Crispin D, Zheng W. Patients with intractable epilepsy have low melatonin, which increases following seizures. Neurology. 2000;55(11):1746-8.

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Brown GM, Pandi-Perumal SR, Trakht I, Cardinali DP. Melatonin and its relevance to jet lag. Travel Med Infect Dis. 2009 Mar;7(2):69-81. Review.

Bylesjo I, Forsgren L, Wetterberg L. Melatonin and epileptic seizures in patients with acute intermittent porphyria. Epileptic Disord. 2000;2(4):203-8.

Chang FY, Lu CL. Treatment of irritable bowel syndrome using complementary and alternative medicine. J Chin Med Assoc. 2009 Jun;72(6):294-300. Review.

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Cos S, Sanchez-Barcelo EJ. Melatonin and mamary pathological growth. Frontiers Neuroendo. 2000;21:133-70.

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Dominguez-Rodriguez A. Melatonin in cardiovascular disease. Expert Opin Investig Drugs. 2012;21(11):1593-6.

Dominguez-Rodriguez A, Abreu-Gonzalez P, Avanzas P. The role of melatonin in acute myocardial infarction. Front Biosci (Landmark Ed). 2012;17:2433-41.

Eck-Enriquez K, Kiefer TL, Spriggs LL, Hill SM. Pathways through which a regimen of melatonin and retinoic acid induces apoptosis in MCF-7 human breast cancer cells. Breast Cancer Res Treat. 2000;61(3):229-39.

Gordon N. The therapeutics of melatonin: a paediatric perspective. Brain Dev. 2000;22(4):213-7.

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Jacobson JS, Workman SB, Kronenberg F. Research on complementary/alternative medicine for patients with breast cancer: a review of the biomedical literature. J Clin Onc. 2000;18(3):668-83.

Kaneko S, Okumura K, Numaguchi Y, Matsui H, Murase K, Mokuno S, et al. Melatonin scavenges hydroxyl radical and protects isolated rat hearts from ischemic reperfusion injury. Life Sciences. 2000;67(2):101-12.

Kim MK, Park EA, Kim HJ, et al. Does supplementation of in-vitro culture medium with melatonin improve IVF outcome in PCOS? Reprod Biomed Online. 2013;26(1):22-9.

Kotlarczyk MP, Lassila HC, O'Neil CK, et al. Melatonin osteoporosis prevention study (MOPS): a randomized, double-blind, placebo-controlled study examining the effects of melatonin on bone health and quality of life in perimenopausal women. J Pineal Res. 2012;52(4):414-26.

Kunz D, Mahlberg R. A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder. J Sleep Res. 2010;19(4):591-6. doi: 10.1111/j.1365-2869.2010.00848.x.

Lagneux C, Joyeux M, Demenge P, Ribuot C, Godin-Ribuot D. Protective effects of melatonin against ischemia-reperfusion injury in the isolated rat heart. Life Sciences. 2000;66(6):503-9.

Lanoix D, Guerin P, Vaillancourt C. Placental melatonin production and melatonin receptor expression are altered in preeclampsia: new insights into the role of this hormone in pregnancy. J Pineal Res. 2012;53(4):417-25.

Lewy AJ, Emens J, Jackman A, Yuhas K. Circadian uses of melatonin in humans. Chronobiol Int. 2006;23(1-2):403-12.

Low Dog T, Riley D, Carter T. Traditional and alternative therapies for breast cancer. Alt Ther. 2001;7(3):36-47.

Lusardi P, Piazza E, Fogari R. Cardiovascular effects of melatonin in hypertensive patients well controlled by nifedipine: a 24-hour study. Br J Clin Pharmacol. 2000;49(5):423-7.

Lyseng-Williamson KA. Melatonin prolonged release: in the treatment of insomnia in patients ages >55 years. Drugs Aging. 2012;29(11):911-23.

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Melmed: Williams Textbook of Endocrinology. 12th ed. Philadelphia, PA: Elsevier Saunders; 2011.

Morceli G, Honorio-Franca AC, Fagundes DL, Calderon IM, Franca EL. Antioxidant effect of melatonin on the functional activity of colostral phagocytes in diabetic women. PLoS One. 2013;8(2):e56915.

Moretti RM, Marelli MM, Maggi R, Dondi D, Motta M, Limonta P. Antiproliferative action of melatonin on human prostate cancer LNCaP cells. Oncol Rep. 2000;7(2):347-51.

Motta E, Czuczwar SJ, Ostrowska Z, et al. Circadian profile of salivary melatonin secretion and its concentration after epileptic seizure in patients with drug-resistant epilepsy--preliminary report. Pharmacol Rep. 2014;66(3):492-8.

Nagtagaal JE, Laurant MW, Kerkhof GA, Smits MG, van der Meer YG, Coenen AM. Effects of melatonin on the quality of life in patients with delayed sleep phase syndrome. J Psychosom Res. 2000;48(1):45-50.

Paul MA, Miller JC, Gray GW, et al. Melatonin treatment for eastward and westward travel preparation. Psychopharmacology (Berl). 2010;208(3):377-86.

Peled N, Shorer Z, Peled E. Pillar G. Melatonin effect on seizures in children with severe neurologic deficit disorders. Epilepsia. 2001;42(9):1208-10.

Piccirillo JF. Melatonin. Prog Brain Res. 2007;166:331-3.

Pignone AM, Rosso AD, Fiori G, et al. Melatonin is a safe and effective treatment for chronic pulmonary and extrapulmonary sarcoidosis. J Pineal Res. 2006 Sep;41(2):95-100.

Pillar G, Shahar E, Peled N, Ravid S, Lavie P, Etzioni A. Melatonin improves sleep-wake patterns in psychomotor retarded children. Pediatr Neurol. 2000;23(3):225-8.

Ram PT, Yuan L, Dai J, Kiefer T, Klotz DM, Spriggs LL, et al. Differential responsiveness of MCF-7 human breast cancer cell line stocks to the pineal hormone, melatonin. J Pineal Res. 2000;28(4):210-8.

Reiter RJ. Melatonin: clinical relevance. Best Pract Res Clin Endocrinol Metab. 2003;17(2):273-85.

Reiter RJ, Tamura H, Tan DX, Xu XY. Melatonin and the circadian system: contributions to successful female reproduction. Fertil Steril. 2014;102(2):321-8.

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Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, Klersy C. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59(1):82-90. doi: 10.1111/j.1532-5415.2010.03232.x.

Rossignol DA, Frye RE. Melatonin in autism spectrum disorders. Curr Clin Pharmacol. 2014;9(4):326-34.

Rossignol DA, Frye RE. Melatonin in autism spectrum disorders: a systematic review and meta-analysis. Dev Med Child Neurol. 2011;53(9):783-92. doi: 10.1111/j.1469-8749.2011.03980.x.

Sack RL, Brandes RW, Kendall AR, Lewy AJ. Entrainment of free-running circadian rhythms by melatonin in blind people. N Engl J Med. 2000;343(15):1070-7.

Schernhammer E, Hankinson S. Urinary melatonin levels and breast cancer risk. J Nat Canc Instit. 2005;97(14):1084-7.

Serfaty MA, Osborne D, Buszewicz MJ, Blizard R, Raven PW. A randomized double-blind placebo-controlled trial of treatment as usual plus exogenous slow-release melatonin (6 mg) or placebo for sleep disturbance and depressed mood. Int Clin Psychopharmacol. 2010;25(3):132-42.

Shamir E, Barak Y, Shalman I, Laudon M, Zisapel N, Tarrasch R, et al. Melatonin treatment for tardive dyskinesia: a double-blind, placebo-controlled, crossover study. Arch Gen Psych. 2001;58(11):1049-52.

Shamir E, Laudon M, Barak Y, Anis Y, Rotenberg V, Elizur A, et al. Melatonin improves sleep quality of patients with chronic schizophrenia. J Clin Psychiatry. 2000;61(5):373-7.

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melatonin hormone - University of Maryland Medical Center

Dr Colin Holloway | Managing hormone imbalances

This website is an avenue for communicating with my patients. I keep very up to date with health issues, especially to do with aging and hormonal problems. I will share the interesting bits with you. I encourage a two-way conversation so please add your comments and opinions. I have a daily blog dealing with health issues. You can subscribe to this free service by entering your email address in the space provided.

I am a GP working in Caboolture, Queensland. I have a special interest in natural hormone treatments, also known as Bio-identical hormones. The name derives from the fact these hormones are identical to the hormones we produce naturally.

I have been using these hormones for the last 20 years, and have treated nearly 4500 people with them.


I have a MB Bch,(Bachelor of Surgery and Medicine). I also have a Diploma in Obstetrics, obtained from the Royal College of Obstetricians and Gynecologists. As well I have a Diploma in Tropical Medicine and Hygiene, obtained at the Witwatersrand University, South Africa. I am a Fellow of the Royal Australian College of GPs. Over my lifetime I have delivered over 1500 babies, an achievement I value highly. Some of those I delivered are now my patients.

Books written:

Having studied diet, lifestyle, health and positive attitudes, I was frequently asked as to why I did not share this knowledge with others more widely. So with the encouragement of my wife, I would get up at 4 am to research and write Live Well Over 100. The first edition of 5000 sold out very quickly, so more study and earlier am starts led to the second edition, which was a lot bigger and more in-depth. The print run of 20,000 sold out fairly quickly as well. I was invited to speak at various health related conferences, something I really enjoyed, as I got to meet people from various parts of the world. I spoke in conferences in New Zealand, Singapore, Philippines, South Africa and Australia of course. Unfortunately, the book is now out of print, and is no longer current as it was written over 15 years ago.

While touring New Zealand and giving talks at various venues, I met Michail Borrisenko, who had a great interest in Colostrum, and the many health benefits thereof. Michail and I coauthored Microbe Apocalypse- Man Vs Microbe'. Michail Borrisenko, is chief scientist, Institute of Colostrum Research, New Zealand.

I wrote The Medical Vitadiet, which has sold over 25,000 copies to date. This deals with the benefits of the low-calorie diet to produce weight loss. At one stage I had 5 weight loss clinics in Queensland, with very successful results. Having decided to move on to other aspects of health, I sold the business, but allowed the new owners to continue to use the book I wrote as part of the program.

Environmental concerns:

When living in Bargara, near Bundaberg, in the 70s and 80s with my family, I became concerned about the threat developers posed to the famous Mon Repos Turtle Rookery. A meeting was called by concerned locals, at which I found myself elected to a committee to fight the threat to Mon Repos. We ran a campaign mainly around environmental issues and won in a landslide. I did 2 terms on the local council and feel we made a difference to the local environment my family and friends lived in. I continued my general practice during this time, which kept me very busy. I am still keenly interested in politics, as the world we live in will be determined by the actions of our leaders, and we need to be ever vigilant to ensure our freedoms and good governments.

Womens Hormones.

Why should women get artificial hormones that are not the same as the natural hormones women produce? It isobvious that the body will react and have side effects to hormones it does not recognize.

Why not use the natural hormone produced by the body? How can the limited dosages available from the synthetic HRT suit all women? You would not be satisfied with a choice of only 2 sizes when buying a pair of shoes. So how much more important is it to have hormones made to measure.

Some of the motivation for this web site is to present the medical evidence and research to reassure men and women about the science behind what I do and to refute some of the nonsense that is said about Natural (Bio-identical) HRT. The big pharmaceutical companies have a commercial interest in women using their products and not the natural form. To this end they spend vast sums in promoting their products to doctors, and give big grants to the various menopause associations. I ask people to keep an open mind and to look at the research available into using hormones.

Dr Colin Holloway | Managing hormone imbalances

Does hormone replacement medication … – Lindora Clinic

These hormones are associated with aging and aging absolutely affects ones weight. Metabolism slows, hormone levels change, and vigorous activity becomes more difficult. However, there is evidence that behavioral changes account for a greater proportion of weight gain than physiological changes.

As we grow older, we usually grow in wealth and free timetime to eat out, relax at home, or take vacations. Menopause also plays a role. One long-term, ongoing study of women before, during, and after menopause (the Rancho Bernardo Womens Study) has shown that women tend to gain weight more rapidly during and after menopause.

To many peoples surprise, average weight gain is more rapid in those not taking hormones than in those taking hormones. But it bears repeatingweight gain tends to occur in women during and after menopause, whether or not they choose hormone replacement therapy (HRT).

According to the Postmenopausal Estrogen and Progestin Intervention (PEPI) Trial, women on placebo experienced a much larger weight gain than those receiving supplemental hormones, but even they experienced a small weight gain during the three years of the trial (J Clin Endocrinolog Metab. 1997; 82: 1549-1556). While the women on placebo gained an average of 4.6 lbs., the women taking estrogen alone gained 1.5 lbs. The estrogen administered was the type found in Premarin and Prempro. The women taking estrogen along with a progestin, either cyclically to approximate a natural cycle or continuously also gained weight2.9 lbs. with cyclical Provera and 2.0 lbs. with a type taken daily. Those assigned to a micronized progesterone gained 2.9 lbs.

Medroxyprogesterone acetate (Provera) is the most common progestin prescribed in HRT. It is the progestin component of HRT that is most often associated with bloating and weight gain. Progestins are various synthetic versions of progesterone, the hormone secreted by the ovaries during the second half of the menstrual cycle if ovulation has occurred.

Progesterone, often considered a fattening steroid hormone, promotes fat synthesis and storage, as this would contribute to a successful pregnancy. Pregnancy requires a tremendous expenditure of energy (i.e. calories) and progesterone, whose name suggests its function (pro=for, gest=gestation), facilitates this in several ways. It increases appetite and slows down intestinal transit time, thus allowing more of the digested nutrients to be absorbed. It can also sometimes decrease insulin sensitivity (the action of insulin at the cellular level), resulting in a degree of insulin resistance which can elevate blood sugar. This conserves glucose for the fetus for growth and development, though at the expense of the mother. Progesterone can also result in the retention of sodium and water, which also contributes to weight gain. However in a non-pregnant state, the increased glucose resulting from the increased absorption of an increased amount of food is absorbed by fat cells causing weight gain. The levels of progesterone during pregnancy are, however, much higher than the levels normally found during the luteal phase of the menstrual cycle and are also higher than the progestins supplied in HRT.

Further, women with a uterus should not take estrogen without a progestin, since this increases the risk of endometrial cancer significantly. For those women who cannot tolerate progestins, an annual endometrial biopsy (usually an office procedure) is recommended if they choose to take estrogen. Whether or not such surveillance adequately prevents cancer has yet to be determined; further study is needed.

Estrogen can also promote sodium (salt) and water retention, increasing blood volume which is important in pregnancy since it increases delivery of nutrients etc. to the fetus. But in a non-pregnant state it can result in weight gain. The weight gain is often temporary since the body eventually adjusts to shifts in fluid. Haarbo and Associates reported that abdominal fat deposition is significantly lower in HRT users. Although all women in this Finnish study gained weight, the HRT users gained less weight and fat overall than non-users. Further, removal of the ovaries in mice, resulting in a lack of estrogen and progesterone similar to the hormonal situation in post-menopausal women, results in massive weight gain due, at least partially, to a greatly increased food intake. Administration of estradiol results in a return of food intake to normal levels and a consequent weight loss.

In women administration of GnRH agonists such as Lupron and other drugs which have the effect of shutting down the ovary are also notorious for causing weight gain, often a large amount (more than can be explained by an increased appetite). The exact mechanism underlying this remains unclear, as does the mechanism underlying menopausal weight gain.

In conclusion, its probably not the fault of the hormone replacement medication that most women gain weight through menopause. Having said that, we often see women whose weight gain was very closely associated with starting hormone therapy. Like most things, some women likely develop much more significant side effects than others do. Its interesting to note that women in some countries tend to lose weight during and after menopause. This is very closely related to activity and diet changes. For instance, in Southeast Asia, women raising young children have more access to food and are less active than their older counterparts who return to work in the factories or fields.

Does hormone replacement medication ... - Lindora Clinic

FEMME CLINIQUE – Bio-Identical Hormone Therapy Clinic …

Femme Clinique is Bellevues premier life enhancement clinic for women who want to get more from life. From sexual enhancement to healthy aging and longevity we can help you maximize your potential from the inside out using bio-identical hormone therapies.

In todays world we are constantly being exposed to chemicals that can severely affect the hormone milieu. When your hormones are out of imbalance you may experience symptoms which can range from uncontrollable weight gain or loss to severe fatigue and low mood.

An obvious symptom of hormonal imbalance is PMS (premenstrual syndrome) which is usually due to a progesterone and/or estrogen deficiency. Hormones effect everything including how we feel and think. Progesterone can help improve relaxation and sleep and estrogen is important for mental clarity. A more extreme example of estrogen deficiency is Alzheimers disease.

Another problem is that as we age our hormones tend to decline (ie menopause). Many women are afraid to do hormone replacement because they have been told it might increase their risk of cancer. The truth is that science has advanced. We can now measure hormone levels accurately and decrease cancer risks. Also, all the studies that showed increase risks were from studies using horse hormones. Premarin is a horse hormone mix.

Using hormone therapies that help your body restore balance can help you regain your optimal health. Bioidentical hormone therapies have been used for thousands of years to help women regain health and vigor for life. The Chinese used bioidentical hormones 1,000 years ago in 1025 AD. Your naturally produces hormones and bio-identical hormones are identical to the hormones your body produces.

We can help you balance your hormones with lifestyle, diet, exercise, and bio-identical hormones. For example, if you are post-menopause then you may need need to apply an estrogen cream topically daily. In addition, some women need a little testosterone cream. While women need much less testosterone than men, you still naturally produced a little testosterone when you were younger. Progesterone, oxytocin, testosterone, estrogen, and thyroid hormones are all important to have in balance.

Pamela Smith, MD, MPH discusses disease prevention

If you are looking for a holistic solution to health aging and balancing your hormones naturally, then theNatural Hormone Replacement Therapyis right for you. This treatment program is designed to help you balance the key hormones Progesterone, Oxytocin, Testosterone, Estrogen, Thyroid, and more.

Your physician can help you determine how best to balance your hormones to increase your wellness and reduce your health risks. Becoming a patient is easy and your first visit includes labs and thorough review of your top health concerns and health history. Based on your specific needs your physician will recommend specific treatments and possibly additional lab testing. Our services are concierge so we invite you to contact us with any questions or concerns throughout the process.

Call (425) 274-2777 with any questions, to schedule, or schedule your new patient visit (we accept most insurance) online:

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FEMME CLINIQUE - Bio-Identical Hormone Therapy Clinic ...

San Antonio Natural Hormone Therapy Clinic | Bio-Identical …


For years, women have coped with menopause through hormone replacement strategies that addressed the problem instead of the patient. Recently, hormone replacement therapy has been refined so that current therapies are tailored and delivered directly to the patient. Dr. Neera Bhatia is pleased to offer one such therapy, BioTE, that is at the forefront of this design process. BioTE is widely regarded as one of the superior bio-identical hormone replacement therapies available.

Dr. Bhatia's mission statement includes a focus on incorporating innovations that further patient welfare into her practice. With this commitment in mind, Dr. Bhatia is the ideal physician to guide patients through the process of bio-identical hormone replacement therapy. Through nearly 35 years in practice, Dr. Bhatia has seen the approach to hormone replacement therapy develop. Now, there is a solution for patients that she fully endorses and promotes BioTE pellets.

Briefly, bio-identical hormones are plant derived and biologically engineered to match the patient's own hormones. These hormones represent the most recent advancement in hormone replacement therapy and represents a solution for both women and men.

Exclusive Interview

Continued here:
San Antonio Natural Hormone Therapy Clinic | Bio-Identical ...

The Endocrine Clinic | Singapore Hormone Specialists

Dr.Chia graduated with Bachelor of Medicine and Bachelor of Surgery from the National University of Singapore in 1999, for which she was awarded the Singapore Medical Association Bronze Medal for being 2nd in the overall examination. She was also honored with the Dean's List Award, the Yeoh Khuan Joo Gold Medal (Surgery) and the Nestle Book Prize ( Paediatrics Clinical Clerkship). She decided to pursue her passion for internal medicine and completed her residency at the Singapore General Hospital. She obtained membership of the Royal College of Physicians of the United Kingdom in 2002. Following this, she embarked on her fel-lowship training in the field of Endocrinology at the Department of Endocrinology, Singapore General Hos-pital (SGH).

In 2004, whilst still pursuing her subspecialty training in Endocrinology, Dr Chia was given a research fellow-ship at the Cleveland Clinic Foundation, USA. During this one and a half year period, she conducted research on blood markers for the diagnosis and management of thyroid cancer, for which she was awarded the Merlin Bumpus Young Researcher Award (2nd prize) by the Cleveland Clinic Foundation. Upon her return to Singa-pore, she completed the rest of her Endocrinology fellowship in 2007, and was admitted as a Fellow of the Academy of Medicine, Singapore.

Dr Chia has always been passionate about teaching, and has been heavily involved with both undergraduate and postgraduate education. She was Chairman of the SGH Division of Medicine Medical Officer Education Committee from 2006 to 2008, as well as a Clinical Tutor at the Yong Lou Lin School of Medicine at the Na-tional University of Singapore.

Dr Chia has wide ranging interests particularly in thyroid disease and diabetes. She is the current chairman of the SGH Thyroid Group, a multidisciplinary association of physicians with an interest in the care of patients with thyroid cancer. She is the only endocrinologist in Sinapore so far to receive the specialist credential En-docrine Certification in Neck Ultrasound (ECNU) from the American Association of Clinical Endocrinologists (AACE). This rigorous credential is only awarded to endocrinologists who have satisfied a high standard for performing thyroid and neck ultrasounds, as well as ultrasound-guided biopsies of thyroid nodules.

Dr Chia also has a great interest in managing diabetes, and strongly believes in empowering both physician and patient in combating this growing problem. To this end, she has given numerous educational talks on dia-betes to the medical community, both internationally and locally. Besides this, Dr Chia also manages oste-oporosis, calcium disorders, obesity, polycystic ovarian disease, lipid disorders, pituitary and adrenal disorders and other hormonal evaluations. She is the incumbent honorary secretary of the Endocrine & Metabolic Soci-ety of Singapore and the Chapter of Endocrinologists, Academy of Medicine. She is an active member of The Endocrine Society (USA) and the American Association of Clinical Endocrinologists (AACE).

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The Endocrine Clinic | Singapore Hormone Specialists

Bioidentical Hormone Replacement Therapy for Men and Women …

Bio-Identical Hormone Replacement Therapy, along with proper nutrition and exercise has the ability to return men and women to the optimal mental, physical, emotional and sexual health they had when they were younger adults. Bio-Identical hormone replacement BHRT therapy has renewed the lives of millions of men and women with hormonal imbalances by significantly improving their quality of life and their health.

Natural, Bio-Identical hormone replacement therapy (BHRT) has been used with great success by patients throughout Europe and the United States since the 1930s to improve the lives of millions of men and women with hormonal imbalances. Unlike conventional hormone therapy, which uses synthetic hormones, Bio-Identical hormone replacement therapy uses naturally derived hormones in the proper levels to eliminate symptoms of hormone imbalance. Bio-Identical hormones are identical to the hormones produced naturally by the human body.

Natural bio-identical hormone replacement therapy, under a doctor's supervision, is a safe and effective treatment that significantly improves the quality of life and health of people suffering from age-related hormone imbalance.


Benefits of Bio-Identical hormone replacement therapy for women may include the elimination of night sweats and hot flashes, vaginal dryness and itching, improved energy levels, improved fat loss and muscle tone, improved mood and sex drive, improved memory and concentration and may reduce risk of heart disease.


Benefits of Bio-Identical hormone replacement therapy for men may include improved muscle mass, tone and energy levels resulting in improved exercise endurance, improved fat loss, improved muscle tone, improved mood and sex drive, improved memory and concentration, improved sleep patterns, and improved cholesterol levels.

Bio-Identical hormones are most commonly prescribed to treat symptoms of hormonal imbalance in women and men, such as hot flashes, night sweats, decrease or loss of libido, weight gain, fatigue, mood swings and irritability.

Many patients choose Bio-Identical Hormone Replacement Therapy (BHRT) because it is prescribed on an individualized basis and does not fall into the category of a one-size-fits-all type of approach.

Dr. Jason Collins has extensive experience in both natural and conventional medicine and insures that each Bio-Identical hormone regimen is custom-compounded and is based on each patient's individual diagnostic results, making them not only safer, but also more effective than traditional synthetic hormones.

Studies show that natural Bio-Identical hormone replacement therapy for men and natural Bio-Identical hormone replacement therapy for women significantly improves ones quality of life and health while decreasing the risk of developing chronic illnesses in the future.

Read the rest here:
Bioidentical Hormone Replacement Therapy for Men and Women ...

Denver Hormone Therapy | Denver Hormone Health

Hormone ImbalanceTest

Are you experiencing exhaustion, moodiness, low libido, weight gain or hot-flashes? Find out if your symptoms can be corrected with Bioidentical Hormone Therapy.

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BHRT utilizes hormones that are chemically identical to those already in your body. These natural hormones are not created in a lab, but come from plants and animals.

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Experiencing symptoms of low testosterone but not sure if you indeed have low levels? Check today with asimple Testosterone Test. You deserve to know!

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Stephen A. Goldstein, M.D., F.A.C.S. founded Denver Hormone Health on the central belief that no man or woman should have to suffer needlessly at the hands of hormone imbalances.

Dr. Goldstein has been studying Bioidentical Hormone Replacement Therapy (BHRT) and anti-aging medicine since 1999. He understands the detailed nuances of balancing hormones (tailored to meet your unique needs). He has also personally experienced the positive impact Bioidentical Hormone Therapy has had on his own health.

Born in Spartanburg, South Carolina and raised in Nashville, Tennessee, Dr. Goldstein was awarded an academic scholarship to the University of Tampa where he received a B.S. degree in Chemistry. H

e went on to receive his M.D. from the University of Tennessee College of Medicine, and completed his General Surgery and Plastic Surgery Residency at Brown University.

Dr. Goldstein firmly believes in continuing education and attends numerous professional meetings and conferences yearly to remain in touch with the latest technological advances. Read More

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HD Medspa & Clinic | Lakeview Neighborhood, Chicago, for …

The HD Med Spa and Clinic, located the the Lakeview neighborhood, Chicago Illinois, near the heart of Boystown, specializes in Microdermabration, Botox treatments, Laser Hair Removal, Lipo B, Cryoprobe Skin Lesion Removal, Facials, Chemical Peels and Naprapathy.

Dr. Harold Diaz also provides Chicago hormone replacement therapy, as well as physician-supervised bioidentical testosterone / estrogen replacement programs and secretogogue therapies designed to treat adult men and women over the age of 3O suffering from symptoms and problems associated with low hormone levels (andropause/menopause) within the Chicago area. See Dr. Diaz's blog for more information about hormone replacement therapy.

Our weight loss program is a contemporary, physician-conducted and monitored approach to weight loss, based on current research and the clinical experience of Dr. Diaz. The program focuses on lifestyle changes, which eventually will help patients keep off unwanted or extra pounds.

If you have any questions or would like to make an appointment, Contact Dr. Diaz.

If you have any questions or would like to make an appointment for a naprapathic treatment, please Contact Dr. Venice.

Treatments and Services:

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Bioidentical Hormone Replacement Therapy – Amen Clinics

For many years, the most commonly prescribed drug in the nation was a synthetic estrogen made from horses urine (Premarin). Premarin in pill form is offered in five different dosages. In recent years, studies have linked negative outcomes to conventional hormone replacement therapy, such as increased risk of cancer and heart disease. Today, conventional hormone therapy is approached more cautiously.

Recent years have seen the emergence of bioidentical hormone replacement therapy, which takes a more individualized, natural approach to hormone replacement. In bioidentical hormone replacement therapy (BHRT), hormones are biologically identical to human hormones on a molecular level, which is believed to help the body accept the hormone more effectively and avoid side effects commonly experienced with synthetic hormones. Additionally, bioidentical hormones are prescribed on a case-by-case basis based on the specific dosage needs of each patient. Instead of just five dosage options, none of which may be right for you, your Amen Clinics doctor can determine any dose that you specifically need and it will get made for you. This individualized approach makes far better sense than a one size fits all approach no two people are exactly the same, so why would their hormone levels be? And since our bodies are so sensitive to hormone levels, precision dosages are ideal.

At Amen Clinics, we offer individualized dosages and combinations of the following hormones, which we carefully administer based on your unique hormone profile determined in yourbiomedical evaluation.

Estrogen is the major female sex hormone (though men have it, too). When a woman doesnt have enough of it, it impacts her libido, her immune system, her mental health and her heart health, to name a few. Menopause is the time in a womans life when estrogen production naturally falls off, leading to such common side effects as hot flashes, forgetfulness, mood swings, vaginal dryness and depression. This is why menopause is the time in life when most women think about hormone replacement therapy. Estrogen replacement has been shown in studies to improve cognition in post-menopausal women. It can also normalize the ups and downs of menopause and help women regain and maintain a feeling of normalcy and wellbeing.

Much more than a female sex hormone, progesterone can support GABA, the brains relaxation neurotransmitter (progesterone receptors are highly concentrated in the brain). We like to think of progesterone as the feel-good hormone. When progesterone is low, women can experience anxiety and depression, sleep difficulty and bone loss. Many women can become what is known as estrogen dominant and can suffer a litany of problems due to this relative lack of progesterone (think PMS). Progesterone replacement can be incredibly helpful for women who have problems that get worse with their menstrual cycle.

The primary male sex hormone, testosterone in men is responsible for sex drive, muscle mass, bone density and an overall sense of wellbeing. Andropause is the gradual decrease of testosterone production in older men, a little bit like menopause is to women. With its anti-inflammatory properties, testosterone has been connected to chronic pain. In women, testosterone helps protect the nervous system and ward off depression and Alzheimers disease.

The thyroid gland drives the production of many neurotransmitters that run the brain. If your thyroid is low, you feel sluggish, mentally foggy and depressed; if its high, you feel anxious, jittery and irritable. Experts conservatively estimate that one-third of all depressions are directly related to thyroid imbalance. Low thyroid function remains one of the most under-diagnosed medical conditions in the country and proper evaluation and treatment of this condition is vital to both mental and physical health.

Dehydroepiandrosterone (DHEA) is a precursor hormone to the sex hormones, meaning testosterone, estrogen and progesterone are all converted from DHEA. Stress can take a toll on DHEA levels, which when low have been linked to weight gain, depression and chronic pain. Conversely, studies show that higher levels of DHEA as you age are associated with longevity.

In some severe cases of fatigue and excessive stress over a long period of time, the adrenal glands may become fatigued or unable to cope with the bodys demand for adrenal hormones. There are natural ways to support the adrenal gland, but in some cases replacing adrenal hormones with prescription medications like cortisol can have a dramatic effect on improving quality of life. Adrenal hormones should be evaluated and replaced by an expert in hormone replacement therapy.

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Human growth hormone (HGH): Does it slow aging? – Mayo Clinic

Human growth hormone (HGH): Does it slow aging?

Human growth hormone is described by some as the key to slowing the aging process. Before you sign up, get the facts.

Growth hormone is produced by the pituitary gland a pea-sized structure at the base of the brain to fuel childhood growth and help maintain tissues and organs throughout life. Beginning in middle age, however, the pituitary gland slowly reduces the amount of growth hormone it produces.

This natural slowdown has prompted an interest in the use of synthetic human growth hormone (HGH) to stave off some of the changes that occur with age, such as decreased muscle and bone mass.

If you're skeptical, good for you. There's little evidence to suggest human growth hormone can help otherwise healthy adults regain youth and vitality. In fact, experts recommend against using HGH to treat aging or age-related conditions.

Yes. Adults who have true growth hormone deficiency not the expected decline in growth hormone due to aging may be prescribed synthetic human growth hormone by their doctors.

Growth hormone deficiency in adults is rare and may be caused by pituitary adenoma a tumor on the pituitary gland or treatment of the adenoma with surgery or radiotherapy. For adults who have a growth hormone deficiency, injections of human growth hormone can:

Human growth hormone is also approved to treat adults with short bowel syndrome or AIDS- or HIV-related muscle wasting.

Studies of healthy adults taking human growth hormone are limited. Although it appears that human growth hormone can increase muscle mass and reduce the amount of body fat in healthy older adults, the increase in muscle doesn't translate into increased strength. It isn't clear if human growth hormone may provide other benefits to healthy adults.


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Human growth hormone (HGH): Does it slow aging? - Mayo Clinic

What are Hormones? – Hormone Replacement Therapy Denver

By Dr Dale Baird

Hormones are chemicals the body uses to direct our cells to perform various tasks. The tasks performed involve almost every function, from insulin production to brain intellectual development. They are in most abundance in our earlier years of life. When we are young, we dont really know how lucky we are to have fully functioning hormones. But at age 47-53 for most women, they start going away, its called in Menopause(for men its andropause). Symptoms of waxing and waning hormones are; weight gain, low or no energy, sleep disruption, no sexual desire, osteoporosis, heart disease, looking as if youre rapidly aging. There are many hormones (even Vit D is considered a hormone in some circumstances) but the main ones we usually deal with are the following; Estrogen, Testosterone, Progesterone, DHEA, Melatonin, and Cortisol. Both Estrogen and testosterone are derived from progesterone and DHEA. A healthy cholesterol level is important because all hormones are derived from it.

Estrogen is what makes a women different from a man, like wise Testosterone is what makes a man a man. Both of them are involved with the osteoporosis as is progesterone. All of these are very necessary for a healthy heart, brain, lungs, hormone system, digestive system.

As we age these hormones become less plentiful leading to the aging process. Hormone Replacement is the medical process of re-establishing normal known hormone levels. These levels are just about the same no matter what age you are! So when you use hormones to establish normal levels, we are essentially rolling back the clock, 20 to 30 years in most cases.

Hormone levels are dropping in younger age groups more than ever before. Our clinic sees the equivalent of a 70 year old levels with males and females in their mid twenties. More now than ever before, younger people are needing hormone replacement therapy (HRT).

HRT is not for everyone, some illnesses preclude hormones and hormone replacement. Call an HRT specialty Doctor to see if you need your hormones levels measured.

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What are Hormones? - Hormone Replacement Therapy Denver

Medical Weight Loss Clinic of Utah – Hormone Replacement …

Individualized Weight Loss Programs Read More

We take a physical / health approach to weight loss. There are hundred of people that diet and exercise daily and they still gain weight or they cant loose weight, this is not because they are cheating on their diet. Its because something is wrong with their body and their metabolism. Conditions that cause weight gain, also cause other symptoms i.e fatigue, brain fog, depression, anxiety, hair loss, feeling cold, belly weight, diabetes, low hormones and more. We customize our physician supervised weight loss programs for each of our patients after analyzing their unique health situation.

whether you have difficulty losing weight or are suffering from diabetes-related issues, PCOS, infertility, seemingly incurable migraines, or a host of other conditions.

At Medical Weight Loss and Hormone Replacement Clinic we dig deep to find the underlying causes of your health issues, then our physicians, dedicated staff, and nutritionists work directly with you to help solve your health problems!

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Medical Weight Loss Clinic of Utah - Hormone Replacement ...

Home – Seattle Hormone Replacement Clinic for Men

Our hormone levels decline with aging. We begin experiencing lack of energy, decrease in exercise tolerance and sexual drive. We gain weight, acquire heart disease and diabetes; we loose muscle strength, and our bones become fragile.

Such detrimental changes should not be ignored!

Weshould actively seek for ways how to continue to be and stay energetic and productive, even when years take toll on us.

Hormone Replacement Therapy (HRT) and, in particular, testosterone replacement has become increasingly popular among middle age men.

In addition to a healthy diet and active lifestyle, optimal hormone levels aid men to be at their best.

A recently published study, which included 930 men with coronary artery disease, showed that men who had a lower level of Testosterone (even borderline levels!) had almost twice higher chance of dying during seven years of follow-up. (Heart. 2010; 96:1821-1825)

At our clinic, we constantly review the most recent medical articles and strive to improve our protocols in order to bring you the best possible outcomes from your hormone therapy. Though subjective results may vary, most men on hormone replacement feel and function better than those who are not.

If you have any questions about Testosterone Replacement, DHEA, Thyroid or other hormone optimization, please CALL us today at (206) 792-5700 to discuss your personalized hormone replacement program.

We will carefully review your medical history and tailor a hormone replacement program right for you.

We can help YOU to feel your BEST!

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Home - Seattle Hormone Replacement Clinic for Men

Long Island Hormone Therapy Clinic NY, Anti-Aging Clinics …

Hormone Replacement Therapy Nutraceutical Imbalance Therapy IV Nutrient Therapy Medical Weight Loss Sexual Dysfunction Treatment GH Releasing Hormones You may be reading this because you are not your normal self. You are lethargic and your energy level is not what it was. Your body is becoming soft and flabby. You're having problems with focus and concentration. LEARN MORE Core Medical New York has an extensive menu of nutraceuticals, available via oral delivery or injection, that accelerate the anti-aging process in our patients. Our neutraceuticals range from high performance, gender-specific multi-vitamins to essential amino acids that can melt away body fat. LEARN MORE IV nutrient therapy is the process of giving vital nutrients to the body via the bloodstream. The nutrients can be distributed slowly with a syringe, as in the "Meyer's Cocktail," for five to fifteen minutes or by a slow drip that can last from thirty minutes to just over an hour. LEARN MORE Small doses of HCG, given to overweight individuals, decreases appetite, and assists in trimming off inches of fat, specifically around the hips, thighs, buttocks, and stomach in a few short weeks. LEARN MORE Core Clinic takes a multi-faceted approach to treating erectile dysfunction. The first step is an evaluation by one of Core's highly-trained physicians to identify what is causing erectile dysfunction. Upon completing the evaluation, an individualized treatment regimen is created by a Core physician. LEARN MORE Core Medical New York's objective in providing physician-supervised, adult Sermorelin growth hormone therapy, is to reverse the negative effects of aging and secure the extensive treatment benefits. LEARN MORE Core Medical New York is a group of professionals, dedicated to revolutionizing the anti-aging process. Core strives to bring an innovative approach to conquering the countless adverse effects of aging experienced by many adult men and women. We design for each client a customized program with the sole objective of improving their quality of life.

We also specialize in Erectile Dysfunction (ED) and Testosterone Replacement Therapy!

Call us today so we can help you out of the shadows of hormone imbalances! FOR A FREE CONSULTATION, CALL (844)NYC-CORE

These medicines are available only with a doctor's prescription. As such, you must be examined by our physician who will determine what products are medically necessary and provide you with instructions for proper use and administration. Core Medical New York will be happy to connect you with one of the many physicians in its network so you can learn more about our products and so that you, together with a qualified physician, can determine if our products are right for you. Please note that Core takes its responsibility to its patients very seriously and as such complies with all relevant statutes, rules and regulations, including but not limited to 21 U.S.C. 801-971 and 21 U.S.C. 301, et seq. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch or call 1-800-FDA-1088.

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HGH Therapy | HGH Clinics | Human Growth Hormone Therapy

Since 2003, AAG Health & Wellness has pioneered the field of health, vitality and wellness for men and women who want to achieve specific health goals.

We combine ongoing expertise in clinical research related to every area of wellness, with access to a unique team of board-certified physicians, wellness coaches and nutritionists at our hormone therapy clinics.

Our expertise is in the integrative field of age management and anti-aging. Our unique approach enables our clients to achieve optimum performance, productivity and appearance in the most efficient way possible.

Please find below a list of our most popular treatment plans designed to make you look good and feel better than ever:

We also offer a great selection of diagnostic tests at our clinics that are designed to identify health and wellness markers:

All of the above play a crucial role in our integrative wellness approach to age management. Here are some of the results our clients have reported after visiting our wellness centers:

If youre ready to supercharge your life, give us a call at (866) 734-5771 for a free consultation or to get more information about our integrative wellness programs.

Together, well help you feel young and stay healthy so you can accomplish more in life.

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HGH Therapy | HGH Clinics | Human Growth Hormone Therapy

Bio-Identical Hormones & Women’s Services at Dr. Wright’s …

The Tahoma Clinic has a variety of programs for women who are interested in optimizing their health. The programs range from basic gynecological exams, menopausal support, gynecological conditions such as endometriosis and fibroids, to prevention against osteoporosis, Alzheimers, cardiovascular disease, and cancers. Each program is individualized to meet personal needs, as well as address your prior history and family history.

Our most popular program involves evaluation and use of Bio-identical natural hormone replacement therapy. The Tahoma Clinic offers the latest in Bio-identical natural hormone replacement therapy for women in a safe and effective manner. Dr. Jonathan Wright, MD originated the Triest blend of estrogens 25 years ago and is still leading the way today. Dr. Wright currently has two physicians on staff specializing in womens health, and has worked extensively with each of them in Bio-identical natural hormone replacement therapy.

Menopause is a natural process a womans body goes through as she ages. Many different approaches can be taken to help address this change. Diet and lifestyle are always at the core of the program. Vitamins, minerals, and other supplements as necessary are then added to support the foundation. Lastly, the Bio-identical hormones, which look exactly like the hormones you produce in your own body and originate from wild yam or soy, are formulated for you.

As we age, our hormone levels change. For example, as early as 30 years of age, our DHEA levels start declining. At the same time, our Cortisol starts to rise. This combination can result in weight gain, especially around the middle, increasing your risk of cardiovascular disease and insulin resistance. Other symptoms that occur with menopause include:

Each woman experiences these changes to varying degrees. There are many different approaches to managing your symptoms, and we will work with you to find the treatment that best supports your needs. To start, your hormone levels will be evaluated by a 24-hour urinalysis which allows for multiple metabolites to be measured accurately. Then, a physician will work with you to focus on methods to help you balance your hormones safely and effectively for your natural body composition.

Please , pleasecontact usto make an appointment with one of our doctors that specialize in womens health.

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Male Hormone Replacement – Testosterone – The Turek Clinic

The average age of men in the US is projected to rise significantly over the next 25 years, with the greatest increase occurring in men > 65 years old.

As this happens, there will be a dramatic increase in age-related health problems too, including cancer, strokes, heart disease and hormone deficiency. Although the health risks associated with age-related hormonal decline in women, termed menopause, have been thoroughly addressed, it has now been shown that hormonal changes in the aging male are associated with significant health problems.

Specialty board certified Dr. Paul Turek at The Turek Clinic, a Best Doctors in America choice for 7 years running, has expertise and interest in helping patients understand all of the issues, good and bad, that surround testosterone replacement therapy in men of all ages.

To learn more about male hormone replacement, please select one of the following topics. If you are ready to schedule a consultation with Dr. Turek, please request a consultation here.

There is a progressive decline in testosterone production in men with age. These changes can be dramatic, such that 50% of men >60 years old have low levels of testosterone. Although the rate of decline varies widely, a general rule of thumb is that testosterone levels decrease about 1% yearly after age 50. Despite the fact that it is not as rapid a drop in hormones as women get with menopause, it certainly is just as real. This has been termed male menopause, male climacteric, andropause, or more appropriately, partial androgen deficiency in the aging male (PADAM). Serum testosterone levels in men fall progressively from the third decade to the end of life, mainly due to a decline in the cells in the testis that make the hormone (Leydig cells). This decline may also be due to changes in hormones (GnRH, LH) and proteins (SHBG, albumin) that regulate testosterone production.

One issue with testosterone that complicates matters is the fact that it exists in several different forms in the blood, and each form has different hormonal activity (Figure 1). Free or unbound testosterone is a fully active hormone, but protein-bound testosterone are only partly active, or sometimes completely inactive. What is usually measured in a blood draw is the total testosterone, which is a combination of the free and protein-bound forms. An analogy to explain this is to think of the total testosterone as all of the cars in a parking lot.

Importantly, though, only the cars that can start or drive are useful or active. Free testosterone comprises all of the cars that can start and be driven away, but the protein-bound testosterone are those cars that may or may not start, and those that may or may not be able to be driven away. So, aging is associated with 1) lower total testosterone production (fewer cars in the lot) and 2) higher levels of certain proteins that bind testosterone (sex hormone-binding globulin, SHBG), such that even fewer cars can start and run, and it is this combination of events that leads to declining testosterone activity with age. Thus, the complex physiology of testosterone balance often clouds the interpretation of age-related declining levels of the hormone.

Testosterone affects the function of many organs in the body (Table 1). In the brain, it influences libido or sex drive, male aggression, mood and thinking. Testosterone can improve verbal memory and visual-spatial skills. It as also been shown to decrease fatigue and depression in men with low levels. It is responsible for muscle strength and growth, and stimulates stem cells and blood cells in bones and kidneys. Penile growth, erections, sperm production, and prostatic growth and function all depend on testosterone. It also causes body hair growth, balding, and drives beard growth. Thus, testosterone makes us who we are, and influences how we look.

In men with low testosterone levels, testosterone can improve bone mineral density and reduce bone fractures, an effect similar to that found in postmenopausal women on estrogen replacement. Importantly, hip fractures are 2-3 times as likely to kill an older man as a woman of the same age, and 40% of older male patients with hip fractures die within 1 year of the injury.

Testosterone results in increases in lean body mass, possibly strength and can decrease fat mass. By stimulating erythropoietin, testosterone increases blood counts. It appears to improve lipid profiles and dilates blood vessels in the heart but no data has yet shown that it reduces heart attacks or strokes. It appears not to alter LDL or total cholesterol levels. In recent work, it has been shown that men with chronically low testosterone levels have 2-3 fold higher risk of developing metabolic syndrome and have up to a 40% greater risk of death than men with normal testosterone levels.

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Male Hormone Replacement - Testosterone - The Turek Clinic

Hormone clinic to open – News Sentinel Story

Patients in need of hormone replacement therapy will have another option when a dedicated treatment clinic opens next week in West Knoxville.

Balanced Solutions at 9051 Executive Park Drive, suite 203, hopes to fill a void left in the market after the closing of HRC Medical in January. HRC had been under state investigation for safety concerns.

If HRC had done it the correct way, it would have been such a tremendous clinical benefit to our region. They didnt. I think we have the potential to provide that, said Dr. Michael Fields, owner and medical director of Balanced Solutions.

Balanced Solutions has three patient rooms with another two rooms available for expansion. It focuses on bioidentical hormone replacement therapy, primarily injectable hormone pellets.

Bioidentical hormone replacement therapy uses plant-derived hormones that are formulated to be a direct exact copy chemically and molecularly as the hormones produced by the human body, said Fields, who also serves as Turkey Creek Medical Centers director of robotic surgery.

Since HRC Medical closed, patients in need of such therapy have had limited access to treatment, relying on individual physician practices. HRC Medical also had focused on bioidentical hormone replacement but closed after the state attorney general sued the company for misleading customers and failing to warn them of potential health risks.

Fields said his clinic is focused on the health of the patient.

We are focused on the medicine, not selling someone a product. Every patient will see a clinician. This is very individualized per patient, he said.

Balanced Solutions plans to take a global approach to the patient. In addition to bioidentical hormone replacement therapy, patients will be counseled on various wellness components such as nutrition, weight loss and exercise.

I never thought Id have the opportunity to be involved with something like this, he said. Its a significant service to the region and to the patients.

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Dallas Anti Aging Clinic for Men | Male Hormone …

1 on 1 Confidential Consultation with Dr. Armani for Male Hormone Therapy in Dallas, TX NO SALES COUNSELORS

In addition to being a contributor to scientific articles, Dr. Abraham Armani has been a consulting advisor to or acknowledged/featured as an expert physician in CNBC, Wall Street Journal, Fox News Radio, Health Radio, CBS Radio, Readers Digest and Dermatology Times as well as other media outlets.

Dr. Abraham Armani has been presented the PATIENTS' CHOICE AWARD for providing outstanding patient care.

Call or email today to schedule a free, personal consultation with Dr. Armani about anti aging and male hormone replacement therapy in Dallas, TX.

Phone: (972) 2 ARMANI (972) 227-6264

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How Can Armani Anti Aging in Dallas, TX Help?

Dr. Abraham Armani MD is a well recognized Dallas anti-aging specialist who uses the latest scientific methodology from across the world to treat his patients. As a member of the American Academy of Anti-Aging Doctors, Armani helps his patients in Dallas, Texas look and feel their best.

We start with a thorough medical history and examination. Dr. Armani's focus is on normalizing male hormone levels using laboratory testing and a proven scientific protocol.

We offer bio-identical male hormone therapy in Dallas, which includes Testosterone, HCG as well as guidance on overall health improvement techniques and decisions.

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Women’s Mood & Hormone Clinic / Moms Program | UCSF …

This clinic provides expert consultation and treatment for women, especially new mothers or mothers-to-be, in cases where hormone function, especially during and after pregnancy, may influence the female brain -like, mood changes, trouble sleeping, depression, worries, anxiety, irritability, decreased ability to focus and concentrate, decreased energy, difficulty connecting with the baby, anxiety, libido and well-being. Examples of the types of symptoms we treat include (but are not limited to):

The Women's Mood & Hormone Clinic / Moms Program also sees teen girls and women with general complaints related to mood, anxiety, sleep and libido - whether or not hormone involvement is suspected as the cause. For example, women with depression, anxiety disorders, sexual complaints, or psychiatric medication issues may be seen by the clinic.

Please keep in mind that we are a clinic specializing in the psychological aspects of hormones on the female brain. If you are seeking medical assistance regarding endocrine diseases, please consult an endocrinologist. If you are uncertain about whether we will meet your needs, please discuss the contents of this website with your primary care physician, enodcrinologist, neurologist, pediatrician, OB-gyn, psychologist, or psychiatrist.

For an appointment, please call our intake and referral service at (415) 476-7500 or toll-free at (800)723-7140.

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Women's Mood & Hormone Clinic / Moms Program | UCSF ...