Advanced Genetics- mod showcase - 1.6.x 1.7.x (Get the powers of any minecraft mob!)
Vandaag hebben we een compleet DNA-Lab in de kelder opgezet. Eremus zal de krachtigste superheld worden in heel Minecraft MUAHAHAHA.... Follow us on twitter...

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Advanced Genetics- mod showcase - 1.6.x & 1.7.x (Get the powers of any minecraft mob!) - Video

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Ramin Pashaie on Optogenetics - (optics + molecular genetics)
Could we possibly help blind people to see real life the way they see dreams? Ramin Pashaie thinks we can!

By: UWM CEAS

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Ramin Pashaie on Optogenetics - (optics + molecular genetics) - Video

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The Genetics of Autism Spectrum Disorder
"The Genetics of Autism Spectrum Disorder" is presented by Christian Schaaf, M.D. , Ph.D., Assistant Professor, Department of Molecular and Human Genetics - Baylor College of Medicine and...

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PCMag Live 07/25/14: Google X Genetics Sharknado 2 Light Show
Samara Lynn Max Eddy chat about the day #39;s top tech news, including a WSJ report that Google #39;s Baseline Study project will collect anonymous genetic and mol...

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PCMag Live 07/25/14: Google X Genetics & Sharknado 2 Light Show - Video

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Character Genetics Live Episode One 07-25-14

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Character Genetics Live Episode One 07-25-14 - Video

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Groovy Genetics: Strawberry DNA Extraction
Did you know that you can extract DNA from a strawberry right in your own home -- or your local library? Kids who attended the recent Groovy Genetics program...

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Lets Play The Sims 3 Perfect Genetics-100 Baby Challenge Part 1
Watch the CAS and finding a house for our founder. -- http://www.twitch.tv/gbabychallenger/c/4750293 utm_campaign=archive_export utm_source=gbabychallenger utm_medium=youtube.

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Lets Play The Sims 3 Perfect Genetics-100 Baby Challenge Part 1 - Video

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Freezing Zero cap 13 28ava Generacion de West Genetics III
Agradecimientos por la traduccion Santos-Scans visita http://santos-scans.me/ MUsica: X-Ray Dog - Night Hounds [Modern Drama] On Your Knees (No Guitar Melody) Learning To Fly Audiomachine-P...

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Freezing Zero cap 13 28ava Generacion de West Genetics III - Video

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Perfect Genetics challenge Part:2
Hey guys!!Hope you enjoy!Walking dead LPS coming soon!

By: RavenTheGamer

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Perfect Genetics challenge Part:2 - Video

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Lets Play The Sims 3 Perfect Genetics-100 Baby Challenge Live Stream Part 5
Perfect Genetics and 100 Baby Challenge all in 1 -- http://www.twitch.tv/gbabychallenger/c/4765765 utm_campaign=archive_export utm_source=gbabychallenger utm_medium=youtube.

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Mower Genetics - Vanilla Kush
Hi its my Vanilla Kush (G-Pheno) 2mont old Only natural water ! Without chemics !

By: Radek Pika

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PUBLIC RELEASE DATE:

29-Jul-2014

Contact: Catherine Afarian cafarian@23andme.com 23andMe Inc.

23andMe, the leading personal genetics company, has received from the National Institutes of Health (NIH) a grant totaling $1,367,504 for a two-year project to support the further development of 23andMe's web-based database and research engine for genetic discovery.

Specifically, the grant supports four areas of development:

"23andMe is building a platform to connect researchers and consumers that will enable discoveries to happen faster," said Anne Wojcicki, co-founder and CEO of 23andMe. "This grant from the NIH recognizes the ability of 23andMe to create a unique, web-based platform that engages consumers and enables researchers from around the world to make genetic discoveries."

The grant will enable 23andMe to refine current survey questions, release 15 new questionnaires, and discover novel associations between health conditions and genetic variants. The company will publish new discoveries in peer-reviewed scientific journals.

The grant also supports improvements to survey infrastructure and the creation of new tools for collection of phenotypic data. This will improve the usability of surveys, including an updatable health profile where participants can keep track of known health conditions and add simple interactive cognitive tests to the 23andMe website.

The grant also supports 23andMe's efforts to utilize available whole-genome sequence data and imputation in order to discover rare variants associated with disease. 23andMe will impute genotypes using data from large public and internal sequencing projects, thus providing increased power to detect many novel associations, including rare variants with large effects. This type of analysis represents a model for how previous investments in genome-wide association studies will be utilized in the next generation of genetics research.

The grant's final area of support is the company's efforts to collaborate with academic and commercial partners to test and refine the Research Accelerator. The Research Accelerator provides access to aggregate de-identified genotype and phenotype data from 23andMe customers who have consented to participate in the company's research program. 23andMe will give a limited set of partners early access to the Research Accelerator and will create reports and tools so that partners are able to see which single nucleotide polymorphisms (SNPs) are associated with conditions of interest; to find conditions associated with variants in individual genes; and to view other aggregate data. By providing access to the de-identified aggregate data, individual-level information remains protected while researchers from around the world have an opportunity to use genetic and phenotypic data from 23andMe to make discoveries.

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23andMe scientists receive approximately $1.4 million in funding from National Institutes of Health

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AUSTRALIAN Sheep Breeding Values have proven their accuracy for more than 20 years, taking much of the guesswork out of breeding sheep.

But according to Sheep Genetics manager Hamish Chandler, it is up to stud and commercial breeders to get the most out of them.

Sheep Genetics has nearly 900 clients in Australia, including more than 500 terminal breeders, and additional clients overseas including some in the United States and New Zealand.

The national genetic evaluation system which operates under the brands of MERINOSELECT and LAMBPLAN has delivered significant genetic gains.

At the sold-out Sheep Genetics breakfast seminar held during the recent LambEx in Adelaide, Mr Chandler highlighted the large variation between the rate of gain between the top 20 per cent and bottom 20pc of producers and potential to drive greater profits.

He said there was almost a $2 a ewe joined per year difference between the rate of gain of the top 20pc and bottom 20pc of producers of maternal breeds on the Maternal $ index. And while Merinos were a diverse gene pool, the MP+ Index varied around the same amount.

In terminals, the variation in average rate of genetic gain was 50 cents/ewe joined from the Lamb 20:20 index, but there was nearly 60c/ewe joined/year difference between the top and bottom producers.

He challenged stud breeders to see where they fitted in the scale and how they could improve the genetics for their clients.

Some 70pc of terminal rams sold each year had ASBVs, 40pc of maternals and only 20pc of Merinos.

Mr Chandler said it was pleasing to see participation rates among Merino breeders rising and the industry looking to improve the ewe flock.

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Guess less with genetics

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A new stem-cell discovery might one day lead to a more streamlined process for obtaining stem cells, which in turn could be used in the development of replacement tissue for failing body parts, according to UC San Francisco scientists who reported the findings in the current edition of Cell.

The work builds on a strategy that involves reprogramming adult cells back to an embryonic state in which they again have the potential to become any type of cell.

The efficiency of this process may soon increase thanks to the scientists identification of biochemical pathways that can inhibit the necessary reprogramming of gene activity in adult human cells. Removing these barriers increased the efficiency of stem-cell production, the researchers found.

Our new work has important implications for both regenerative medicine and cancer research, said Miguel Ramalho-Santos, Ph.D., associate professor of obstetrics, gynecology and reproductive sciences and a member of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF, who led the research, funded in part by a prestigious NIH Directors New Innovator Award.

The earlier discovery that it was possible to take specialized adult cells and reverse the developmental clock to strip the mature cells of their distinctive identities and characteristics and to make them immortal, reprogrammable cells that theoretically can be used to replace any tissue type led to a share of the Nobel Prize in Physiology or Medicine being awarded to UCSF, Gladstone Institutes and Kyoto University researcher Shinya Yamanaka, M.D., in 2012.

These induced pluripotent stem (iPS) cells are regarded as an alternative experimental approach to ongoing efforts to develop tissue from stem cells obtained from early-stage human embryos. However, despite the promise of iPS cells and the excitement surrounding iPS research, the percentage of adult cells successfully converted to iPS cells is typically low, and the resultant cells often retain traces of their earlier lives as specialized cells.

Researchers generate stem cells by forcing the activation within adult cells of pluripotency-inducing genes starting with the so-called Yamanaka factors a process that turns back the clock on cellular maturation.

Yet, as Ramalho-Santos notes, From the time of the discovery of iPS cells, it was appreciated that the specialized cells from which they are derived are not a blank slate. They express their own genes that may resist or counter reprogramming.

But the nature of what exactly was getting in the way of reprogramming remained poorly understood. Now, by genetically removing multiple barriers to reprogramming, we have found that the efficiency of generation of iPS cells can be greatly increased, he said. The discovery will contribute to accelerating the safe and efficient use of iPS cells and other reprogrammed cells, according to Ramalho-Santos.

Miguel Ramalho-Santos

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Stem cell discovery may make tissue regeneration more efficient

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Released: 29-Jul-2014 8:00 AM EDT Source Newsroom: Mayo Clinic Contact Information

Available for logged-in reporters only

Newswise JACKSONVILLE, Fla. Imagine a future in which a new lung is grown for a patient in need, using the patients own cellular material, or a day when an injection of replacement cells will enable a patient to self-heal damage in the brain, nerves or other tissues.

MULTIMEDIA ALERT: For audio and video of Dr. Keller and Jorge Bacardi talking about the gift and regenerative medicine, visit the Mayo Clinic News Network.

Regenerative medicine is no longer science fiction, and a substantial gift from Jorge and Leslie Bacardi of the Bahamas will significantly accelerate the research of Mayo Clinics Center for Regenerative Medicine on the Florida campus.

Jorge Bacardi, whose family has manufactured rum and other spirits for 150 years, suffered since childhood with primary ciliary dyskinesia, a debilitating lung disease that nearly ended his life. A double lung transplant at Mayos Florida campus in 2008 enabled him to take his first full breath of air at age 64.

Regenerative medicine is an extraordinary step in the evolution of mankind, says Jorge Bacardi. It is for Leslie and I a great honor to be able to join Mayo Clinic in the development of such an advancement in the medical field."

Regenerative medicine is addressing the root causes of disease and disability by developing ways to rejuvenate the body using its natural self-healing processes; replace damaged cells with healthy ones derived from the patient (avoiding immune system rejection); and regenerate function by applying specific cells or cell products.

Mayos regenerative medicine researchers are targeting conditions throughout the body, including heart disease, stroke, Alzheimers disease and traumatic injuries that affect combat veterans. Some studies are in the earliest stages. Others are in clinical trials with patients.

Researchers now can differentiate stem cells into skin, brain, lung and many other types of cells. For example, a patient's own skin cells may be collected, reprogrammed in a laboratory to give them certain characteristics, and then delivered back to the patient to treat diseases at various places within the body.

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Bacardis Make Gift to Significantly Advance Mayo Clinic's Regenerative Medicine Research

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Natalie Buchoz - Learning to Walk After a Spinal Cord Injury with Help from NuStep
Natalie was 15 years old when she was involved in a skiing accident that left her paralyzed. Doctors told her she would never walk again, but she wouldn #39;t ta...

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Tampa Bay, FL (PRWEB) July 28, 2014

Nearly 53 million Americans today are suffering with arthritis, with the majority of them diagnosed with osteoarthritis. (1) Osteoarthritis is a degeneration of joint cartilage and its underlying bone, causing significant pain and stiffness. While osteoarthritis has no cure, stem cell therapy has been demonstrated to induce profound healing in many forms of arthritis, according to the Stem Cell Institute. (2) Dr. Cynthia Elliott of Skinspirations, a center for cosmetic enhancement devoted to non-surgical aesthetics and now also specializing in administering regenerative medicine by stem cell, has made use of these services in a recent case study, which resulted in improved health in one of their clients.

Stem cells are unique from other cells for the following reasons:

(a)They can renew themselves through cell division; and (b)Under certain conditions, they can become tissue or organ-specific cells.

Stem cells are revered for their ability to make replacement tissues, as it relates to regenerative therapy. (3) Medical scientists and researchers are discovering the seemingly endless possibilities of what stem cells can treat, including brain damage, bone repair, kidney disease, etc. (4) This treatment is starting to boom in the medical world as a viable procedure, but Skinspirations has already had these practices in place, establishing them as progressive practitioners in the field.

Skinspirations is specifically studying the Stromal Vascular Fraction (SVF)another term for stem cell treatmentand how it affects knees with severe arthritis. According to Dr. Elliott, Stromal Vascular Fraction can help to repair, replace and restore any damaged cells within the bodyDr. Elliott performed the stem cell procedure on her uncle after first treating other patients during her training, and he experienced the following results:

Case in Point:

Joe Elliott, a 63-year-old male, had severe arthritis in one knee. Doctors advised him to get a knee replacement, but Joe was hoping to avoid surgery for as long as possible. After talking to Dr. Elliott about the treatment, he drove to Skinspirations from Missouri to go forward with the stem cell procedure.

Dr. Elliott performed the treatment with the following steps:

(1)Numbed his abdomen with anesthesia; (2)Removed about 100 cc of fat; (3)Processed the fat to isolate the SVF; (4)Numbed the arthritic knee; and (5)Injected the pellet of SVF into the joint of his arthritic knee.

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Skinspirations Study Supports Medical Findings: Stem Cell Treatment Triggers Tissue Regeneration

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by Cathy Marshall, KGW Staff

kgw.com

Posted on July 28, 2014 at 3:41 PM

Updated today at 8:20 PM

PORTLAND-- An Oregon man with multiple sclerosis is seeing remarkable results after a stem cell transplant.

All aspects of my life have improved, said 28-year-old Dan Tiel, I dont even walk with a cane anymore.

Tiel's mother first learned of the clinical trial at Northwestern University while doing research on Facebook.

I had been searching for hope for 10 years and this was the first time I really felt it, Gina Tiel said.

Dr. Richard Burt said about 80 patients a year are getting the stem cell transplants at Northwestern for a variety of autoimmune diseases.

We give them their own stem cells that we collect from their blood and it regenerates a new immune system, he explained.

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Ore. man gets results from stem cell transplant

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When Karen Mitchell read the popular blog written by teenage terminal cancer sufferer Alice Pyne, not only was she deeply moved but also inspired.

Pride Of Britain winner Alice, who had Hodgkins lymphoma from the age of 12, took to social media to urge people to join the bone marrow register. Karen decided she too would sign up to donate her stem cells and save lives.

But there was one thing holding her back her weight.

She was 25st and had a BMI of 60, well above the healthy range of 18-25, and when she began the online registration for Anthony Nolan with her weight and height 5ft 6in she was rejected as being too fat.

So, instead she sent brave Alice a tweet, promising she would lose weight to join the register. And when Alice replied, urging her not to give up, Karen swore that she would not fail.

Now shes lost an incredible 11st 7lb and next week she will make a life-saving donation in memory of Alice, who died in January 2013.

Alice told me not to give up and I didnt want to let her down, says Karen. Her amazing legacy can go on saving lives and I hope everyone reading this will donate as well not for me but for Alice.

Karen, from Great Yarmouth, Norfolk, had battled with her weight for as long as she could remember. Her teenage years were a misery as she was forced to dress in size 18 clothes. Even turning vegetarian and making her staple food cheese at 15 didnt help solve her weight problem.

I longed to wear trendy clothes like the other girls at my school but I could only shop in the fat section of shops, she says.

Karen married when she was 27 but says she knew when she walked down the aisle in her size 28 wedding dress that the marriage was already doomed.

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'I promised brave cancer teenager Alice I'd lose 11st so I could donate bone marrow'

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What is Okyanos Cardiac Stem Cell Therapy? Cardiac stem cell therapy is a promising new treatment option for advanced heart disease patients. This short video explores the procedure and benefits of adult stem cell therapy for severe

By: Okyanos Heart Institute

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David's Stories from Detroit David in Detroit for Netroots Nation 2014 On the Bonus Show: A Russian man beats the bank at it's own game, stem-cell therapy gone awry, Rhode Island's accidental legal prostitution experiment

By: David Pakman Show

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Kellie van Meurs, pictured with her husband Mark, died while undergoing stem cell treatment in Russia. Photo: Facebook

Supporters of a Brisbane mother-of-two who died while undergoing a controversial stem cell treatment in Russia say it did not cause her death, nor have others been discouraged from seeking it.

Kellie van Meurs suffered from a rare neurological disorder called stiff person syndrome, which causes progressive rigidity of the body and chronic pain.

She travelled to Moscow in late June to undergo an autologous haematopoietic stem cell transplant (HSCT) under the care of Dr Denis Fedorenko from the National Pirogov Medical Surgical Centre.

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Cell Therapy IPS Cell Therapy IPS Cell Therapy

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What is Okyanos Cardiac Stem Cell Therapy?
Cardiac stem cell therapy is a promising new treatment option for advanced heart disease patients. This short video explores the procedure and benefits of adult stem cell therapy for severe...

By: Okyanos Heart Institute

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What is Okyanos Cardiac Stem Cell Therapy? - Video

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Stem Cells to Renew the Health and Lives of People - Aishwarya Rai Bachchan in Chennai
Stem Cells to Renew the Health and Lives of People - Aishwarya Rai Bachchan in Chennai - RedPix 24x7 #AishwaryaRai #AishwaryaRaiBachchan #StemCells #LifeCell LifeCell is India #39;s first and...

By: Red Pix 24x7

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Stem Cells to Renew the Health and Lives of People - Aishwarya Rai Bachchan in Chennai - Video

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David #39;s Stories from Detroit
David in Detroit for Netroots Nation 2014 --On the Bonus Show: A Russian man beats the bank at it #39;s own game, stem-cell therapy gone awry, Rhode Island #39;s accidental legal prostitution experiment...

By: David Pakman Show

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David's Stories from Detroit - Video

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Even as the Genetic Engineering Appraisal Committee (GEAC) decided to constitute a sub-committee to review the toxicology data generated by two applicants for genetically modified brinjal, biologist Dr. Pushpa M. Bhargava has questioned the guidelines of the Department of Biotechnology (DBT) on transgenic crops.

Dr. Bhargava and others had asked for the raw data on toxicity studies on rats using transgenic brinjal, which were carried out by Dr. Sesikeran, former director of National Institute of Nutrition at Hyderabad.

He found statistically quite significant differences between rats fed on Bt Brinjal and those fed on a normal meal in respect of several important parameters, said Dr. Bhargava.

However, Dr. Sesikeran had said that as all the values (both of the control and of the experimental animals) fell within the normal range of variation, the differences were not significant, and that there was no need to repeat the experiment.

Our point was that if on repetition the same differences are found again, they are bound to be significant, Dr. Bhargava pointed out. Further, he used only 20 animals (10 female and 10 male) in both experimental and the control groups, which is the minimum number for such tests. Dr. Sesikeran must explain why only a minimum number was used, he said.

In a letter to Dr. Ranjini Warrier, member-secretary, GEAC, on July 23, Dr. Bhargava, who was responding to the two emails of July 20 from Dr. Sesikaran to all the members of GEAC, said, According to Dr. Sesikeran, DBT guidelines of 2008 say the following in regard to Interpretation of results of safety studies: The design and analysis of the study should be kept as simple as possible, avoiding unnecessarily complex, sophisticated statistical techniques. If the design is simple, the statistics are likely to give straightforward results. Non-statistical knowledge must be applied in study design and proper interpretation of the biological significance of the results. Just because two treatments are statistically significantly different does not mean that the difference is large enough to have any biological importance or any practical significance.

Dr. Bhargava said he would like to know which international body endorsed this as scientifically; it does not make any sense. In fact, every sentence in this statement is flawed. For example, what is meant by the statement, If the design is simple, the statistics are likely to give straight forward results. Then, what is Non-statistical knowledge that must be applied in study design and proper interpretation of the biological significance of the results.

Further, the last sentence is biased and misleading, he said.

Surely, if the same statistically significant difference between the control and the experimental group in regard to a particular parameter is observed in repeated experiments, it is bound to have biological importance irrespective of the values falling or not falling between the normal range of variation. This can be verified by referring to any independent biology-oriented statistician of stature in India or abroad, Dr. Bhargava pointed out.

He asked the GEAC to respond to some questions he has raised in the next meeting.

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DBT guidelines questioned on toxicity studies for Bt brinjal

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A DNA molecule strand with human genome code. Photograph: Steven Hunt/Getty Images

The unravelling of the human genetic blueprint has delivered a revolution in the study of health and disease. It is having an impact on treatments today and this will carry forward well into the coming century, a Nobel Prize winner has said.

Prof Aaron Ciechanover was speaking yesterday on the margins of a research conference under way at the Trinity Biomedical Sciences Institute in Dublin. He won a shared Nobel Prize in chemistry in 2004 for his study of how the body breaks down and disposes of unwanted proteins.

We are part of a revolution that will change the whole world of medicine, he said. New methods that grew out of molecular biology now help scientists discover the underlying genetic causes of disease and then identify drugs that might help in treatments. And it will help deliver drugs with fewer side effects, he said.

But we are also entering a period when privacy will be a thing of the past, when your genetic blueprint will reveal things hidden in the genome, he said. It will also separate sex from reproduction given access to advanced technologies. It is going to be major, he said.

Molecular biology will also help support personalised medicine, said Prof Bruce Beutler who shared the 2011 prize in medicine and physiology. Many genetic diseases like type II diabetes and rheumatoid arthritis are caused by an unlucky combination of [altered] genes, he said. But the mix of 100 or 200 that causes it in one person may be different in the next.

Once the combination is established the most effective drug treatment can be provided for that individual. That is what personalised medicine will be in the future, he said.

It is hugely important that all governments fund basic research, suggested Prof Jules Hoffmann, who shared the 2011 Nobel Prize in medicine and physiology for his work on the immune system.

When he started research 40 years ago no one doubted the value of discoveries that came from it. This has changed everywhere, he said. It was a mistake to abandon basic research in favour of translational research, he warned, however.

I am absolutely convinced every country needs applied research, he said, but applied research can arise only through conducting basic research. All of the big medical research discoveries arise as a result of basic research, he said.

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Genetics research to revolutionise medicine, says Nobel laureate

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