Stem Cell : cervical vertebral stenotic myleopathy case - Blood stem cells
Atassia is a disease that affects the nervous system. In this specific case the horse was ten years old, and the diagnosis had been given when he was about a year old and over the years it had worsened as do most neurological pathologies. The fact that the horse improved by 70% over two months means that the stem cells that I use have the power to change themselves into nerve cells. This confirms " in vivo" that we have adult pluripotent stem cells, which, unlike fat and bone marrow stem cells, can change themselves into nervous tissue. We have some published papers that credit us with the discovery of pluripotent receptors in blood stem cells obtained "in vitro" with our patented system. In this first video the horse is totally uncoordinated and for months it had been impossible to ride him because the horse risked falling with the rider on top. You can see the notable rear muscle mass #39; atrophy.From:marcopolettiniengViews:34 1ratingsTime:04:55More inScience Technology

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[RMS] Bone Marrow Stem Cell - OSSRON
Ossron is cultured autologous bone cells for bone formation. Ossron is performed by three stages : harvesting bone marrow from a patient #39;s own, cell culturing in stem cell processing center, and implanting the cultured bone cells into defect sites. Bone Marrow Stem Cell [BMSC] Bone marrow cells have shown an osteogenic potential. Only a small aspiration biopsy of bone marrow from the iliac crest is required to obtain these cells. Bone marrow stem cells are the most potent bone regenerator with abundant cell numbers, high viabilites, and highly expressed osteogenic activites. Bone marrow stem cells are able to generate tissue other than bone. These cells can be isolated, expanded in culture, and stimulated to differentiate into osteoblasts, adipocytes, chondrocytes, myocytes, neuronal cells and a variety of other connective tissue.From:SewonCellontechViews:1 0ratingsTime:06:24More inHowto Style

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Public release date: 19-Oct-2012 [ | E-mail | Share ]

Contact: Kim Polacek kim.polacek@moffitt.org 813-745-7408 H. Lee Moffitt Cancer Center & Research Institute

Claudio Anasetti, M.D., chair of the Department of Blood & Marrow Transplant at Moffitt Cancer Center, and colleagues from 47 research sites in the Blood and Marrow Transplant Clinical Trials Network conducted a two-year clinical trial comparing two-year survival probabilities for patients transplanted with peripheral blood stem cells or bone marrow stem cells from unrelated donors. The goal was to determine whether graft source, peripheral blood stem cells or bone marrow, affects outcomes in unrelated donor transplants for patients with leukemia or other hematologic malignancies.

Fifty transplant centers in the United States and Canada participated in this phase III study, which randomized 278 patients to receive bone marrow and 273 patients to receive peripheral blood stem cells as the graft source for transplant. The results of the study are in the Oct. 18 issue of The New England Journal of Medicine.

According to the trial analyses, there were no observed differences in overall survival, relapse, non-relapse mortality, or acute graft-versus-host disease (GHVD) between the patients receiving peripheral blood stem cells or bone marrow stem cells from unrelated donors. GVHD is a serious and often deadly post-transplant complication that occurs when the newly transplanted donor cells attack the transplant recipient's body. While engraftment was faster in patients receiving peripheral blood stem cells, there was a higher incidence of overall chronic GVHD in these patients (53 percent) than in those transplanted with bone marrow stem cells (40 percent). Patients receiving transplants of peripheral blood stem cells from unrelated donors also had a higher incidence of chronic GVHD affecting multiple organs (46 percent) than patients who received bone marrow stem cells (31 percent).

"Although peripheral blood stem cells from related donors have demonstrated clinical benefits, our trial demonstrates that when these stem cells originate from unrelated donors, they are not superior to bone marrow stem cells in terms of patient survival, and they increase the risk for chronic GVHD," said Anasetti, lead study author. "More effective strategies to prevent GVHD are needed to improve outcomes for all patients receiving unrelated donor transplants."

Peripheral blood stem cells are stem cells originally found in the bone marrow that have been moved into the blood stream by a special regimen of drugs. Unlike bone marrow stem cells, which must be extracted from the bones in an operating room, peripheral blood stem cells are more easily obtained through apheresis, a process similar to regular blood donation, which collects the peripheral blood stem cells through a tube inserted in a vein. A critical step before the transplant involves finding a donor that is tissue matched to the recipient.

About one-third of patients who need a peripheral blood stem cell or bone marrow transplant for treatment of leukemia or another blood disease are able to secure a related donor. According to the National Marrow Donor Program, for the 70 percent who cannot find a donor within their family, most will be able to find an unrelated donor. Because the majority of transplant patients need cells from unrelated donors, it's necessary to better understand the risks associated with transplants of unrelated donor cells.

Clinical trials on related donor transplants have demonstrated that peripheral blood stem cell transplants in patients with leukemia and other blood diseases result in better engraftment, lower relapse rates, and increased survival compared with transplants with bone marrow stem cells. However, those trials also found that peripheral blood stem cell transplants carry an increased risk of GVHD. Patients who survive early post-transplant may develop chronic GVHD, a disabling condition managed with long-term immunosuppressant therapy.

Many transplant centers are increasingly using peripheral blood stem cells as a source for adult stem cells because of their superiority in clinical trials that have directly compared outcomes between peripheral blood stem cells and bone marrow stem cells from related donors. However, there has not been a comparative study of the two transplant sources that has prospectively analyzed patient outcomes in unrelated donor transplants.

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Moffitt researcher says no survival advantage with peripheral blood stem cells versus bone marrow

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ScienceDaily (Oct. 19, 2012) Claudio Anasetti, M.D., chair of the Department of Blood & Marrow Transplant at Moffitt Cancer Center, and colleagues from 47 research sites in the Blood and Marrow Transplant Clinical Trials Network conducted a two-year clinical trial comparing two-year survival probabilities for patients transplanted with peripheral blood stem cells or bone marrow stem cells from unrelated donors. The goal was to determine whether graft source, peripheral blood stem cells or bone marrow, affects outcomes in unrelated donor transplants for patients with leukemia or other hematologic malignancies.

Fifty transplant centers in the United States and Canada participated in this phase III study, which randomized 278 patients to receive bone marrow and 273 patients to receive peripheral blood stem cells as the graft source for transplant. The results of the study are in the Oct. 18 issue of The New England Journal of Medicine.

According to the trial analyses, there were no observed differences in overall survival, relapse, non-relapse mortality, or acute graft-versus-host disease (GHVD) between the patients receiving peripheral blood stem cells or bone marrow stem cells from unrelated donors. GVHD is a serious and often deadly post-transplant complication that occurs when the newly transplanted donor cells attack the transplant recipient's body. While engraftment was faster in patients receiving peripheral blood stem cells, there was a higher incidence of overall chronic GVHD in these patients (53 percent) than in those transplanted with bone marrow stem cells (40 percent). Patients receiving transplants of peripheral blood stem cells from unrelated donors also had a higher incidence of chronic GVHD affecting multiple organs (46 percent) than patients who received bone marrow stem cells (31 percent).

"Although peripheral blood stem cells from related donors have demonstrated clinical benefits, our trial demonstrates that when these stem cells originate from unrelated donors, they are not superior to bone marrow stem cells in terms of patient survival, and they increase the risk for chronic GVHD," said Anasetti, lead study author. "More effective strategies to prevent GVHD are needed to improve outcomes for all patients receiving unrelated donor transplants."

Peripheral blood stem cells are stem cells originally found in the bone marrow that have been moved into the blood stream by a special regimen of drugs. Unlike bone marrow stem cells, which must be extracted from the bones in an operating room, peripheral blood stem cells are more easily obtained through apheresis, a process similar to regular blood donation, which collects the peripheral blood stem cells through a tube inserted in a vein. A critical step before the transplant involves finding a donor that is tissue matched to the recipient.

About one-third of patients who need a peripheral blood stem cell or bone marrow transplant for treatment of leukemia or another blood disease are able to secure a related donor. According to the National Marrow Donor Program, for the 70 percent who cannot find a donor within their family, most will be able to find an unrelated donor. Because the majority of transplant patients need cells from unrelated donors, it's necessary to better understand the risks associated with transplants of unrelated donor cells.

Clinical trials on related donor transplants have demonstrated that peripheral blood stem cell transplants in patients with leukemia and other blood diseases result in better engraftment, lower relapse rates, and increased survival compared with transplants with bone marrow stem cells. However, those trials also found that peripheral blood stem cell transplants carry an increased risk of GVHD. Patients who survive early post-transplant may develop chronic GVHD, a disabling condition managed with long-term immunosuppressant therapy.

Many transplant centers are increasingly using peripheral blood stem cells as a source for adult stem cells because of their superiority in clinical trials that have directly compared outcomes between peripheral blood stem cells and bone marrow stem cells from related donors. However, there has not been a comparative study of the two transplant sources that has prospectively analyzed patient outcomes in unrelated donor transplants.

The study was funded by the National Heart, Lung and Blood Institute (U10HL069294), the National Cancer Institute and the National Marrow Donor Program.

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La Prairie Cellular Power Infusion
Recharge your cell energy at the source cellular A never before cell energizer propels your skin toward agelessness. Skin stem cells awaken. Regeneration accelerates. power Supports the cellular power-stations in your cells, allowing them to go into hyper-drive to fuel the cellular-renewal process. A power-surge floods your skin with renewal aliveness. infusion Working from the inside our, your skin tissue is restored with new structure and elasticity. Vibrancy re-ignites... lamination glows... texture silkens. Youthful, moist, firmed resiliency meets your delighted touch.From:TANGSSingaporeViews:425 1ratingsTime:02:47More inHowto Style

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Advocacy in Action: Understanding Biomarker Testing for Lung Cancer
Advocates and doctors discuss the importance of personalizing medicine with biomarker Two advocates, Scott Santarella (President CEO, Bonnie J. Addario Lung Cancer Foundation) and Regina Vidaver, PhD (National Lung Cancer Partnership) discuss personalized medicine, biomarker testing and what patients need to know about this process.From:vitaloptionsViews:0 0ratingsTime:09:22More inNonprofits Activism

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Paralympic Experience in Cedar Rapids
The Adaptive Sport Clinic and Paralympic Experience was held at Kirkwood Community College in Cedar Rapids in March of 2012 to introduce the public to adaptive sports and recreation for people with physical disabilities in eastern Iowa. Sitting volleyball, wheelchair basketball, archery, cycling, bowling, and golf were the activities highlighted at the annual event. Heather Erickson, a member of the US Paralympic sitting volleyball team was in also attendance to share her experiences and motivate attendees. The event was sponsored by SportAbility of Iowa, St Lukes Hospital, Kirkwood Community College, and the Spinal Cord Injury Association of Iowa.From:SportAbilityofIowaViews:9 0ratingsTime:01:06More inSports

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Beacon of HOPE
An awareness video on Spinal Cord Injury Treatment and Rehabilitation in Ganga Hospital, CoimbatoreFrom:Vivek VijayanViews:75 2ratingsTime:11:50More inNonprofits Activism

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SCI Recovery Project, Tyler Hoog #39;s Story.mov
Tyler Hoog became a quadriplegic after an off road jeep accident. This is the story of his accident and rehab at the Spinal Cord Injury Recovery Project in Denver. It was produced by All Video Production and Dan Raymond for their annual fund raiser.From:ShiftyGears2869Views:87 0ratingsTime:12:39More inNonprofits Activism

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Monkey on October 24, 2012
7 Months after Monkey #39;s spinal cord injury and she is bouncing/running with Mia! Shot with my point and shoot it #39;s not the best quality. But at least you can see her running around!From:softservegirlViews:9 0ratingsTime:00:20More inPets Animals

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Maximizing Function: The Role of Rehabilitation" by Herb Karpatkin, PT, DSc
Herb Karpatkin, PT, DSc presents on the role of physical rehabilitation in MS therapy, and how more MS sufferers could benefit from increase rehab opportunities. From the Changing the Future Patient Symposium brought to you by Mount Sinai Medical Center and the Corinne Goldsmith Dickinson Center for MS. bull; Herb Karpatkin, PT, DSc is a certified Multiple Sclerosis specialist from the Consortium of Multiple Sclerosis Centers. He specializes in the treatment of persons with neurologic impairments including Multiple Sclerosis, Stroke, Parkinson #39;s disease, Spinal Cord Injury, Brain Injury, and Cerebral Palsy. Lecture filmed on Sunday 10/16/2011 at the 2011 Corinne Goldsmith Dickinson 3rd Annual MS Symposium, Changing the Future: New Trends in MS Research and Treatment held at the Grand Hyatt, NYC.From:MountSinaiNYViews:15 0ratingsTime:37:07More inEducation

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Spinal Cord Injury Inservice Introduction with OT Judy Ivan
OT Judy Ivan of North Coast Medical briefly explains the levels of spinal cord injury. Please visit http://www.northcoastmedical.com for a complete listing of products recommended for spinal cord injury.From:North Coast MedicalViews:4 0ratingsTime:06:48More inEducation

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Spinal Cord Injury Inservice Product Demonstrations
OT Judy Ivan continues her second part of Spinal Cord Injury Inservice with product demonstrations. Please visit http://www.northcoastmedical.com for more product information.From:North Coast MedicalViews:5 1ratingsTime:06:04More inEducation

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Stories of Hope - Keith Gorski
After sustaining a brain injury during a motorcycle accident, West Palm Beach Police Officer Keith Gorski shares the journey of returning home to his community. Officer Gorski was seriously hurt in the line of duty and was stabilized at St. Mary #39;s Hospital locally and then flown to Shepherd Center in Atlanta for intensive rehabilitation. Shepherd specializes in cutting-edge brain and spinal cord injury rehabilitation, and helped Officer Gorski go far in the recovery process. Gorski is much beloved in West Palm Beach among his police colleagues, Little League coaches, families and players and many others who have staged fundraisers to help defray his medical costs. Gorski is a former stand-out college athlete at the University of South Carolina and has two sons who enjoy playing baseball. While Gorski has made great strides in his recovery, he continues to need additional rehabilitation. Any donations to help offset his medical expenses are greatly appreciated. Tax deductible donations can be sent to LEAF (Law Enforcement Assistance Foundation), PO Box 17725, West Palm Beach, FL 33416, Attn: Keith Gorski Fund.From:KPKinteractiveViews:30 0ratingsTime:08:50More inTravel Events

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WALKAIDE CP INDIA info@rehab-technologies.com
Simple active walking or using your hand for people living with neurological conditions, these everyday activities may be challenging and even sometimes impossible. Enter ADVANCED REHAB TECHNOLOGIES http://WWW.REHAB-TECHNOLOGIES.COM +91 9971038484 Our award winning assortment of rehabilitation products area daily blessing for people living with Stroke(CVA), Cerebral Palsy(CP), Traumatic Brain Injury(TBI), Incomplete Spinal Cord Injury(SCI) and other Central Nervous System(CNS) disorders. Disclaimer: This video is for awareness purposes only. Advanced Rehab Technologies do not own this video.From:AdvancedRehabTechViews:36 0ratingsTime:03:17More inScience Technology

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Tom Lynch, MD / What it means to discover: A researcher #39;s perspective
Thomas Lynch, MD is a thoracic oncologist and director of the Yale Cancer Center. His research is focused on personalized medicine using molecular testing for mutations in tumor genes so that patients can benefit from targeted lung cancer therapies. More on Thomas Lynch #39;s work: yalemedicalgroup.org.From:YaleMedicineViews:3 0ratingsTime:04:13More inEducation

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Tom Lynch, MD / What it means to discover: A researcher's perspective - Video

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Tom Lynch, MD / Meet Yale Physicians: A Personal Perspective on Clinical Practice
Dr. Thomas Lynch is an expert in the treatment of lung cancer with a special interest in personalized medicine. Dr. Lynch has made important contributions in developmental therapeutics and in defining the optimal treatment for patients with lung cancer. He has pioneered the use of molecular testing for mutations in the epidermal growth factor receptor gene to select patients who can benefit from targeted lung cancer therapies. More details on yalemedicalgroup.orgFrom:YaleMedicineViews:2 0ratingsTime:03:36More inEducation

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Attendees Share What Makes CGC Unique and a Must-Attend Event
Attendees from the 2012 Consumer Genetics Conference describe what they like most about this event and why they attend year after year. CGC covers the key issues facing consumer genomics, personalized medicine, advances in sequencing molecular diagnostics, customer-targeted DNA applications, and investment/funding opportunities. It provides a unique outlet where all voices can be heard: pro con, physician consumer, research clinical, academic corporate, financial regulatory. consumergeneticsconference.comFrom:CambridgeHealthtechViews:41 0ratingsTime:03:52More inScience Technology

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CytoComp a revolutionary biological computer
Synthetic Biology (engineering with biological parts) will become a defining science for the 21st century. One very interesting development is cellular computers The recent scientific developments in cellular computing are mind blowing, and will revolutionize the way we will do personalized medicine. Cellular computers are real game changers. Many people (eg diabetics), need to monitor biological functions (eg their glucose levels). It would be great if one could do this in an easy automated way. Moreover, it would be great to automatically regulate these values (eg via insulin) The cellular computer CytoComp is a revolutionary, tiny medical device in the micrometer scale, that let you monitor your biomedical data via a mobile app, and which can self-regulate these functions (eg you avoid to painfully measure your glucose levels; moreover it will self-regulate glucose by insulin production, if needed). Unlike traditional large external devices, CytoComp, which will fundamentally change how we do personalized medicine. CytoComp is tiny (implantable) , self-regulating and thus does not need any action from the user (a diabetic will never again need to care about the glucose level). Copyright CytoComp 2012From:LeukipposInstituteViews:159 5ratingsTime:02:08More inScience Technology

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Panel Discussion: Connectedness and Implications for Personalized Medicine
Moderator: Paul Reeder; Director, Ideation Lab, Office of Technology Commercialization Knowledge Transfer, The Ohio State UniversityFrom:osumedicalcenterViews:2 0ratingsTime:22:04More inScience Technology

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Responsibility of Patients in Personalized Medicine Era, Insung Na at USF
My name is Insung Na. I am a master program student at college of medicine of University of South Florida in USA. I explained the responsibility of patients in personalized medicine era. It was recorded and uploaded to submit my opinion toward TEDxUSF. In current system, severe lethal patients only lean on determination of medical doctors, even though, there are many possible approaches toward the disease in aspect of personalized medicine. Also, it is a problem that it takes too long time to wait novel medicine due to the regulatory system of FDA. However, I think it is possible that each patient determines the procedure of regulatory system for his or her own medication by help of genome consultants, medical doctors, and biomedical scientists. If we can do that, the time effectiveness and survival rate for a patient will be increased.From: #51064; #49457; #45208;Views:77 1ratingsTime:03:35More inScience Technology

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The Future of Medicine: Ben Kompa at TEDxYouth@Columbus
Ben is a senior at Upper Arlington High School, but spends his days taking classes at THE Ohio State University. In addition to playing Bridge, throwing discus, and hanging out with friends, he works in the Sadee Lab of Pharmacogenomics at OSU. There, he was introduced to the possibilities of gene sequencing and personalized medicine, and began conceiving of a world where everyone had individually tailored treatments. In the future, Ben hopes to pursue a degree in biochemistry and continue to conduct research at the crossroads of medicine and public policy In thespirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)From:TEDxYouthViews:374 12ratingsTime:08:54More inScience Technology

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Timothy J. Triche, MD PhD DBRM Retreat 2012 Genomics and Stem Cell Research
Non Coding RNA Functional RNA Transcripts in Cancer and Development Professor of Pathology, Cancer Biology, Pediatrics Keck School of Medicine of the University of Southern California Director, Center for Personalized Medicine at Children #39;s Hospital Los AngelesFrom:Clarence WigfallViews:6 0ratingsTime:17:49More inScience Technology

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Bioscience Connecticut Brings Promise to Future of Medicine
Dr. Frank M. Torti, executive vice president for health affairs and medical school dean, joins "The Hour with Jim Pellegrino" to discuss Bioscience Connecticut and the future of personalized medicine. Aired on multiple community access channels, mid-October, 2012. For more about Bioscience Connecticut: biosciencect.uchc.eduFrom:uconnhealthViews:111 0ratingsTime:24:17More inNonprofits Activism

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IBA - A personalized medicine odyssey
IBA (Ion Beam Applications SA), is a cancer diagnostics and treatment company and the worldwidetechnology leader in the field of proton therapy. The company #39;s expertise lies in the development of nextgeneration proton therapy technologies and radiopharmaceuticals that provide oncology care providers with premium quality services and equipment, including IBA #39;s leading fully-integrated IntegraLab system. Headquartered in Belgium and employing more than 1200 people worldwide, IBA currently has installed systems across Europe and the US and is expanding into emerging markets. The Company is focused on building sustainable global growth for investors and provides high quality services and products for oncology specialists and cancer patients.From:ibagroupViews:103 1ratingsTime:03:43More inScience Technology

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