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NeoStem Receives Notification Of $1.2 million NIH Grant Award For First Clinical Study Of VSELTM Technology In Humans

NeoStem, Inc. (NYSE:NBS ("NeoStem" or the "Company"), an emerging leader in the fast growing cell therapy industry, today announced that it has been awarded a two year grant totaling $1,221,854 for "Repair of Bone Defects with Human Autologous Pluripotent Very Small Embryonic-Like Stem Cells (VSEL)", grant number 2R44DE022493-02A1, from the National Institute of Dental and Craniofacial Research (NIDCR), a division of the National Institutes of Health (NIH). This peer reviewed grant is to support a Phase 2 investigation and first approved NIH clinical study of VSELsTM in humans. The study will be headed by Denis O. Rodgerson, Ph.D., Director of Grants and Academic Liaison for NeoStem, in collaboration with co-investigators Drs. Russell Taichman and Laurie McCauley of the University of Michigan. Enrollment for this study is expected to begin in 2013.

This award will fund the evaluation of VSELTM stem cells as a potential treatment for periodontitis. The product candidate, an autologous therapy derived from a patient's own stem cells, is to be developed for use in the regeneration of bone tissue damaged by this disease. The award includes $706,682 for the first year and $515,172 for the second year of the project, and will cover the cost of the Investigational New Drug (IND) submission to the FDA for the product candidate.

Dr. Denis O. Rodgerson, Director of Grants and Academic Liaison for NeoStem, said, "We are pleased and honored that NIH has agreed to support further studies on bone regeneration by using VSELTM stem cells. This is an extension of our successful NIH funded collaboration with Dr. Taichman showing the production of human bone from human VSELsTM in a mouse model."

Periodontal disease is prevalent in the U.S. and affects up to 90% of the world population. The most severe cases of periodontal disease affect between 5% and 15% of the U.S. population, or between 15 and 47 million Americans. The incidence of periodontal disease is estimated to be between 1 and 3 million Americans annually, and growing at a 7% rate each year. Studies have shown that periodontal inflammation could have a role in the initiation or progression of coronary heart disease and stroke. Market research experts have estimated that severe periodontal disease represents a market between $1.25 and $1.5 billion annually.

Dr. Russell Taichman, Major Ash Collegiate Professor and Co-Director of the Scholars Program in Dental Leadership, Department of Periodontics & Oral Medicine, University of Michigan stated, "I am thrilled for the possibilities that this award opens. The chance to continue to partner with NeoStem to further develop regenerative therapies is significant. The validation that this award brings and the opportunity to establish a proof of concept, which may impact human health, is truly rewarding." Dr. Laurie McCauley, The William K. and Mary Anne Najjar Professor, Division of Periodontics Department of Periodontics and Oral Medicine, University of Michigan added, "This novel cell based therapeutic approach looks to validate scientifically sound pre-clinical studies and provide a vital translation to improved human patient care."

NeoStem has a worldwide exclusive license to VSEL technology which uses very small embryonic-like stem cells, a heterogeneous population of stem cells found in adult bone marrow that have properties similar to those of embryonic stem cells. NeoStem has shown that very small embryonic-like stem cells can be mobilized into the peripheral blood, enabling a minimally invasive means for collecting what it believes to be an important population of stem cells that may have the potential to achieve the positive benefits associated with embryonic stem cells without the ethical or moral dilemmas or the potential negative biological effects associated with embryonic stem cells.

Dr. Robin L. Smith, Chairman and CEO of NeoStem, added, "We are very excited about this important step of funding for what will be the first human clinical study for our VSELTM technology. Not only will this study expand our knowledge of how autologous cell therapy can treat periodontitis and other bone defects, but it represents a milestone for NeoStem as we move our development of VSELTM technology beyond animal models and into the clinic, paving the way for other potential VSELTM trials."

About NeoStem, Inc.

NeoStem, Inc. continues to develop and build on its core capabilities in cell therapy, capitalizing on the paradigm shift that we see occurring in medicine. In particular, we anticipate that cell therapy will have a significant role in the fight against chronic disease and in lessening the economic burden that these diseases pose to modern society. We are emerging as a technology and market leading company in this fast developing cell therapy market. Our multi-faceted business strategy combines a state-of-the-art contract development and manufacturing subsidiary, Progenitor Cell Therapy, LLC ("PCT"), with a medically important cell therapy product development program, enabling near and long-term revenue growth opportunities. We believe this expertise and existing research capabilities and collaborations will enable us to achieve our mission of becoming a premier cell therapy company.

Our contract development and manufacturing service business supports the development of proprietary cell therapy products. NeoStem's most clinically advanced therapeutic, AMR-001, is being developed at Amorcyte, LLC ("Amorcyte"), which we acquired in October 2011. Amorcyte is developing a cell therapy for the treatment of cardiovascular disease and is enrolling patients in a Phase 2 trial to investigate AMR-001's efficacy in preserving heart function after a heart attack. Athelos Corporation ("Athelos"), which is approximately 80%-owned by our subsidiary, PCT, is collaborating with Becton-Dickinson in the early clinical exploration of a T-cell therapy for autoimmune conditions. In addition, pre-clinical assets include our VSELTM Technology platform as well as our mesenchymal stem cell product candidate for regenerative medicine. Our service business and pipeline of proprietary cell therapy products work in concert, giving us a competitive advantage that we believe is unique to the biotechnology and pharmaceutical industries. Supported by an experienced scientific and business management team and a substantial intellectual property estate, we believe we are well positioned to succeed.

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NeoStem Receives Notification Of $1.2 million NIH Grant Award For First Clinical Study Of VSELTM Technology In Humans

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Therafit Gym Multiple Sclerosis Jody MS (stem cell trial).wmv – Video


Therafit Gym Multiple Sclerosis Jody MS (stem cell trial).wmv
PLEASE SEND THE LETTER BELOW TO YOUR US SENATORS! We are writing to encourage the FDA and the Center for Biologics Evaluation and Research (CBER) to approve a clinical trial of mesenchymal stem cell derived neural progenitors (MSC-NPs) in the treatment of Secondary Progressive Multiple Sclerosis (SPMS). The initial 20 person trial will be conducted at the Multiple Sclerosis Research Center of New York (MSRCNY) under the direction of Dr. Saud Sadiq, neurologist and director of the MSRCNY. Dr. Sadiq was previously the head of Neurology at St. Luke #39;s Roosevelt Hospital in New York City (NYC). In 2006, he started this research center in NYC working only on MS. In November 2011, the MSRCNY received approval from the Institutional Review Board (IRB) of the International Cellular Medicine Society (ICMS) to conduct this trial for patients with SPMS, the first of its kind ever done in the US. This trial is very specialized as it uses a patient #39;s own adult stem cells that are removed from the patient #39;s breast bone marrow, grown, isolated and injected into the spinal fluid (intrathecal) where the disease attacks the myelin. The trial will last for 3 years with stem cell treatments every 3 months for the first year and potentially more, depending on the many evaluations to determine physical and mental progress. MSRCNY requested approval in the past and is currently seeking approval for this trial AGAIN!! We are at a breakthrough point in the treatment of patients with SPMS. These ...From:therafitgymViews:11 0ratingsTime:08:46More inNonprofits Activism

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SC12 Attendees Say Keep Producing Tools to Further Research (Tim Carroll) – Video


SC12 Attendees Say Keep Producing Tools to Further Research (Tim Carroll)
@SC12 Dell #39;s Tim Carroll: 125 customer meetings and thousands of people through the booth say: keep producing tools to help the world #39;s research, whether it #39;s small genomics clusters for personalized medicine or the #7 system in the world. http://www.tacc.utexas.edu http://www.dellhpcsolutions.com httpFrom:Janet BartlesonViews:1 0ratingsTime:00:58More inScience Technology

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SC12 Attendees Say Keep Producing Tools to Further Research (Tim Carroll) - Video

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stem cell | Pros And Cons Of Cord Blood Storage Or Cord Blood Banking – Video


stem cell | Pros And Cons Of Cord Blood Storage Or Cord Blood Banking
http://www.cordbloodrecommendation.com After the therapy has done, the patient is then infused using cord blood through a Hickman catheter. Cord blood collection, whether pre or post delivery, entails no pains and risk for both mother and child. 2. There are many diseases that can be treated with stem cells, so if your child ever needs stem cells later in his/her life, you will not have to look for a new donor. Placental and cord blood banking may become even more valuable in the future with exciting research under way to find new medical uses in areas such as: diabetes, heart disease, liver disease, muscular dystrophy, Alzheimer #39;s disease, Parkinson #39;s disease, stroke, and even spinal cord injury. However, in the event that you actually need the cord blood, I am sure there is no price too high for a parent to be willing to pay. In a second time, advances in knowledge of the different types of stem cells and their function will undoubtedly allow soon, the development of new therapies with the ability to repair the dermis of irradiated people and those with big burns. 4) Company Stability Since a baby #39;s stem cells may be stored for a lifetime, it is important to know that the company chosen is stable. Stem cell cord blood has higher probability of becoming the perfect match for family members and relatives and has no risk of rejection by the recipient #39;s body. Yet, with more people considering cord blood banking, whether privately or publicly, it is likely that more miracles can ...From:myc0kyViews:0 0ratingsTime:01:31More inScience Technology

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Bert Burns Speaks as Summa Rehab Hospital – Video


Bert Burns Speaks as Summa Rehab Hospital
When Bert Burns suffered a life-changing injury in his 20s after being thrown from his car during an accident, no one would have blamed him if he decided life as he knew it was over. Facing his future as a quadriplegic, he could have easily viewed the outcome as the end rather than a beginning. Instead, Bert discovered his spinal cord injury to be a blessing in disguise, allowing him to realize dreams that he never would have had before being injured. Today he speaks across the nation, working to help others reclaim their life.From:Summa RehabViews:3 0ratingsTime:10:22More inSports

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How to Perform a Transfer (T1 SCI) – Video


How to Perform a Transfer (T1 SCI)
How to properly initiate a wheelchair to bed transfer for a thoracic level 1 spinal cord injury.From:abeveridge89Views:3 0ratingsTime:01:09More inEducation

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How to Perform a Transfer (T1 SCI) - Video

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Vanessa


Vanessa Laura Marano : A Night By The Ocean Gala with Meaghan Martin
Vanessa and Laura Marano hit the carpet at the Life Rolls On Foundation #39;s 2012 Night by the Ocean Gala held at the Ritz-Carlton Hotel in Los Angeles on Saturday night (November 10). Joined by good friend Meaghan Martin, the young actresses came out to support the foundation which has raised more than one million dollars to support quality of life programs for young people affected by spinal cord injury. "Oh, and I literally had the best time ever at #LifeRollsOn #NightByTheOcean last night! Everyone there is amazing including @katieleclerc :D" Laura tweeted afterwards. Read more: http://www.justjaredjr.comFrom:MrDisneyKingTVViews:0 0ratingsTime:00:21More inEntertainment

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Vanessa

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SWORTEC ® MotionMaker™ – Video


SWORTEC MotionMaker trade;
"While there #39;s life, there #39;s hope" - Marcus Tullius Cicero Neurological patients with movement disorders caused by spinal cord injury, traumatic brain injury, stroke, multiple sclerosis or other neurological diseases, such as cerebral palsy can profit from our patented treatment with MotionMaker trade; and CLEMS trade; electro stimulation. SWORTEC has developed a novel interactive training device and system working closely with leading research institutes and clinics. The new medical technology combines two types of therapy: Functional Electrical Stimulation (FES), enhanced by the central control unit Patient-tailored movement program, that can significantly improve voluntary muscle control in the lower limbs. The development of voluntary muscle control is a vital part of the rehabilitation process, and essential if the patient is to gain maximum benefit from any walk re-education training and activity. Our MotionMaker trade; system is successfully applied at several renowned clinics and research institutes in Switzerland: the SUVA-Care Rehabilitation centre (CRR) in Sion, Swiss Paraplegics Centre (SPC) in Notwill, and the medico-educational centre La Castalie in Monthey. http://www.swortec.chFrom:Samy EisensteinViews:1 0ratingsTime:00:57More inScience Technology

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SWORTEC ® MotionMaker™ - Video

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My name is Seth and this is my continuing story part 3 – Video


My name is Seth and this is my continuing story part 3
This is part 3 in my ongoing video diary entries describing life with a Spinal Cord injury. These entries are meant to motivate and inspire those who think their current situation is beyond hope and life would be extremely difficult or impossible to live. It is also informative for those who might need information related to a spinal cord injury but do not know where to look.From:havnfun370Views:0 0ratingsTime:08:55More inPeople Blogs

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My name is Seth and this is my continuing story part 3 - Video

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Wise Young, MD, PhD at the 2012 Spinal Cord Workshop – Video


Wise Young, MD, PhD at the 2012 Spinal Cord Workshop
Wise Young, MD, PhD Founding Director, WM Keck Center for Collaborative Neuroscience Professor, Department of Cell Biology and Neuroscience Richard H. Shindell Chair in Neuroscience Rutgers, The State University of New Jersey Talk title: Umbilical cord blood and lithium treatment of chronic spinal cord injuryFrom:bedfordstemcellViews:0 0ratingsTime:54:07More inScience Technology

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Wise Young, MD, PhD at the 2012 Spinal Cord Workshop - Video

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Ed Wirth, MD, PhD at the 2012 Spinal Cord Workshop – Video


Ed Wirth, MD, PhD at the 2012 Spinal Cord Workshop
Ed Wirth, MD, PhD Spinal Cord Injury Clinical Scientist Talk title: Cell-Based Therapies for SCI: Lessons Learned in Planning and Conducting Two Phase 1 Safety Trials Over the Past 18 YearsFrom:bedfordstemcellViews:1 1ratingsTime:50:36More inScience Technology

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Ed Wirth, MD, PhD at the 2012 Spinal Cord Workshop - Video

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Nose cell transplant enables paralysed dogs to walk – Video


Nose cell transplant enables paralysed dogs to walk
cientists have reversed paralysis in dogs after injecting them with cells grown from the lining of their nose. The pets had all suffered spinal injuries which prevented them from using their back legs. The Cambridge University team is cautiously optimistic the technique could eventually have a role in the treatment of human patients. The study is the first to test the transplant in "real-life" injuries rather than laboratory animals. Treadmill Of 34 pet dogs on the proof of concept trial, 23 had the cells transplanted into the injury site - the rest were injected with a neutral fluid. Many of the dogs that received the transplant showed considerable improvement and were able to walk on a treadmill with the support of a harness. None of the control group regained use of its back legs. The research was a collaboration between the MRC #39;s Regenerative Medicine Centre and Cambridge University #39;s Veterinary School. Professor Robin Franklin, a regeneration biologist at the Wellcome Trust-MRC Stem Cell Institute and report co-author, said: #39;Our findings are extremely exciting because they show for the first time that transplanting these types of cell into a severely damaged spinal cord can bring about significant improvement. "We #39;re confident that the technique might be able to restore at least a small amount of movement in human patients with spinal cord injuries but that #39;s a long way from saying they might be able to regain all lost function. #39; Prof Franklin said the procedure ...From:NEWSHD2012Views:11300 51ratingsTime:00:21More inPets Animals

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cord blood donation | How Cord Blood Stem Cell Can Bring Hope to People Suffering From Life – Video


cord blood donation | How Cord Blood Stem Cell Can Bring Hope to People Suffering From Life
http://www.cordbloodrecommendation.com A large number of people die waiting for a transplant due to this reason. Well, there are still debates on this issue. Human umbilical cord blood cells are very rich in stem cells and progenitor cells which make them the perfect place to take cells from and then store them in a cord blood bank or a stem cells bank. There is also another option given by non-profit cord blood banks, of free programs through which one can store umbilical cord blood stem cell samples. Others choose to donate the blood to a public bank for the public good. Given the progress that stem cell research and regenerative medicine have attained at present, and the promise that they show for the future, stem cell transplants may one day provide a cure for type 1 diabetes, heart disease, and brain injury, among other potentially life threatening and debilitating illnesses and conditions with inadequate treatment options today. One study in particular by Wagner, et al. ""Settling on a name for your newborn is definitely something all parents spend time doing, but one decision that is rarely thought of or overlooked is saving your newborn #39;s cord blood. However, you can choose to make a once-in-a-lifetime decision to collect and store your baby #39;s cord blood stem cells after the birth of your newborn baby. It is able to kill either normal or cancer-producing blood cells of the bone marrow. Your child #39;s umbilical cord blood contains special cells known as stem cells. Thus, it ...From:Alexander santafeViews:0 0ratingsTime:01:31More inScience Technology

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cord blood donation | How Cord Blood Stem Cell Can Bring Hope to People Suffering From Life - Video

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stem cell | Advantages Of Cord Blood Banking – Video


stem cell | Advantages Of Cord Blood Banking
http://www.cordbloodrecommendation.com Programs Available to Store the Blood There are a small number of programs in the US currently (December 2011) that save cord blood. Before you decide on a specific cord blood bank, contact the AABB to determine if the private blood bank is accredited or if it has any complaints lodged against the facility by other patrons. It really should be observed that the technique has a high risk of complication. Keep in mind that cord blood storage acts as an insurance policy for your family, so consider any other factors before immediately determining not to store your child #39;s cord blood simply because of price. One more cord blood donation might just be enough to save another life. Given the progress that stem cell research and regenerative medicine have attained at present, and the promise that they show for the future, stem cell transplants may one day provide a cure for type 1 diabetes, heart disease, and brain injury, among other potentially life threatening and debilitating illnesses and conditions with inadequate treatment options today. In addition, you have to decide well in advance of the due date because once you lose the precious blood, you cannot regain it. The patient no longer needs to wait for a donor; he can be his own donor if his cord blood had been preserved after his birth. The ultimate decision to bank cord stem cells or not is a personal decision as to what is deemed appropriate for that particular family, but in making that ...From:loshoteles enmedellinViews:0 0ratingsTime:01:31More inScience Technology

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stem cell | Advantages Of Cord Blood Banking - Video

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cord blood registry | The Development of Umbilical Cord Blood Stem Cell Therapy – Video


cord blood registry | The Development of Umbilical Cord Blood Stem Cell Therapy
http://www.cordbloodrecommendation.com These diseases include blood related, genetic and neurotic disorders. ""Banking the umbilical cord blood when your baby is born is a relatively new idea, the first operation using it to help cure a child with Leukemia was only done a little over 10 years ago. After processing of cells, comes the next procedure of cord blood preservation. There is also another option given by non-profit cord blood banks, of free programs through which one can store umbilical cord blood stem cell samples. A man can change his god-gifted features wishfully with the help of science. Given the progress that stem cell research and regenerative medicine have attained at present, and the promise that they show for the future, stem cell transplants may one day provide a cure for type 1 diabetes, heart disease, and brain injury, among other potentially life threatening and debilitating illnesses and conditions with inadequate treatment options today. With people not fully understanding how important stem cells could be for us, everybody agrees that more research need to be done in order to help understand all that. If there is any complication during delivery, the entire idea is abandoned. It is always wise to preserve this waste blood of the baby which is otherwise thrown away. You are injecting the patient with those same cells that created him!This can be done with the bone marrow transplants tooYes, stem cells are found in bone marrows too. It is a simple and ...From:luisantafeViews:0 0ratingsTime:01:31More inScience Technology

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cord blood registry | The Development of Umbilical Cord Blood Stem Cell Therapy - Video

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A dog called Jasper during trial to show spinal cord regeneration – Video


A dog called Jasper during trial to show spinal cord regeneration
In a unique collaboration between the University #39;s Veterinary School and MRC #39;s Regenerative Medicine Centre, scientists used a unique type of cell to regenerate the damaged part of the dogs #39; spines. The researchers are cautiously optimistic that the work could have a future role in the treatment of human patients with similar injuries if used alongside other treatments. For more information, go to http://www.cam.ac.ukFrom:CambridgeUniversityViews:8805 46ratingsTime:00:46More inEducation

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A dog called Jasper during trial to show spinal cord regeneration - Video

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NeoStem – A Global Cell Therapy Company – Video


NeoStem - A Global Cell Therapy Company
From:NeoStemIncViews:5 0ratingsTime:01:53More inScience Technology

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NeoStem - A Global Cell Therapy Company - Video

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Video 7 – November 14, 2012 – Adult Stem Cells Progress.wmv – Video


Video 7 - November 14, 2012 - Adult Stem Cells Progress.wmv
Breif interview of my progress with Multiple Sclerosis with Adult Stem Cell therapy after my experience with Tysabri, Gilenya and Ampira failed.From:MSajourneyfromwithinViews:1 0ratingsTime:04:21More inEducation

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Video 7 - November 14, 2012 - Adult Stem Cells Progress.wmv - Video

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Hair Loss PRP-Stem Cell Therapy-2 month comparison- Large.m4v – Video


Hair Loss PRP-Stem Cell Therapy-2 month comparison- Large.m4v
http://www.newininstitute.com.au PRP Therapy was chosen instead of a Hair Transplant to treat an area of hair loss in a female. 2 month comparison Before and After photos show a highly successful outcome. Note that continued hair growth will occur over the coming months. Another procedure will need to be performed at around the peak period: 12-18 months when growth begins to slow. Newin Institute has uniquely developed processes and protocols for PRP and Adipose Stem Cell Therapy.From:Rhett BosnichViews:0 0ratingsTime:00:55More inScience Technology

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Hair Loss PRP-Stem Cell Therapy-2 month comparison- Large.m4v - Video

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What Are Stem Cells and Stem Cell Therapy Stemenhance – Video


What Are Stem Cells and Stem Cell Therapy Stemenhance
http://www.stemcellproduct.net This video gives you the definition, facts, and understanding on what are stem cells, that there are two of them embryonic and adult stem cells, how they work and the uses of stem cell when the tissue is affected in your body and how messengers signal the bone marrow to release adult stem cells to help in the repair of the injured tissue. Why this information is exciting for me to do a video is because I see stemcells as the best way of how to produce optimal health in your body. The way I look at it is that optimal health equals the number of healthy cells in your body and the only way the body repairs a damaged area is by creating and sending adult stem cells to that area. That #39;s why I #39;m introducing a stem cell product from a nutrition company who patented a stem cell enhancer which supports the release of adult stem cells. What will also excite you too is that Stemtech (the stemcell company) has also come out with two other products that will also optimize the circulation of these stem cells and other nutrients and aid in the ability for them to move and migrate into the affected tissue where they can transform and duplicate into fresh, healthy new cell tissue. So in my eyes having products like these will help anyone in my pursuit of health and wellness. I know it #39;s helping me strengthening my cells in my body after being diagnosed with chronic fatigue syndrome 20 plus years ago because I know how important nutrition and cell help to gain my ...From:Jennifer MarksViews:1 0ratingsTime:06:37More inHowto Style

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ZÉLL-V Sheep Placenta Anti Aging Satisfied Customer – Qiao Ling – Video


ZÉLL-V Sheep Placenta Anti Aging Satisfied Customer - Qiao Ling
http://www.zell-v.com We specialise in cell therapy products for anti aging. we are supported by an international medical board of practitioners, biologist and wellness professionals.From:zellvsheepplacentaViews:5 0ratingsTime:01:56More inHowto Style

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ZÉLL-V Sheep Placenta Anti Aging Satisfied Customer - Qiao Ling - Video

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Bio-Matrix' Regen BioPharma Initiates Pre-Clinical Study in Support of HemaXellerate(TM) Cell Therapy

SAN DIEGO, CA--(Marketwire - Nov 19, 2012) - Bio-Matrix Scientific Group, Inc. ( OTCQB : BMSN ) announced today that its wholly owned subsidiary, Regen BioPharma, Inc., has contracted Cascade Life Sciences, Inc. to research the safety and efficacy of Regen's HemaXellerate product usingmice models for testing.Cascade Life Sciences is a privately-owned San Diego-based company with a platform of stem cell related technologies that are being advanced to serve the research community and the commercial development of stem cell-based therapeutics. Sophia Khaldoyanidi, M.D., Ph.D. is the principal investigator of the study.

The results of Regen's study will provide the safety profile data required for filing of anInvestigational New Drug (IND) application for the product with the US Food and Drug Administration .Regen intends to file an IND Application in the fourth quarter of 2012 and conduct Phase I/II clinical trials during 2013 and 2014.

HemaXellerate offers the possibility of delivering a population of endothelial cells to restore blood production in patients with hematological conditions."Unlike current approaches of administering pharmaceuticals," said J. Christopher Mizer, President of Regen BioPharma, "our strategy is to heal the bone marrow by administering cells that provide the optimum mix of growth factors to stimulate the bone marrow into producing blood cells naturally."

Regen has submitted two provisional patent applications covering the use of different sources of endothelial cells to heal damaged bone marrow. These applications cover: (1) placental cells (61/648898 - Acceleration 0f Hematopoietic Reconstitution by Placental Endothelial and Endothelial Progenitor Cells); and (2) fat cells (61/670791 - Treatment of Hematopoietic Disorders).

About Bio-Matrix Scientific Group Inc. and Regen BioPharma, Inc.:

Bio-Matrix Scientific Group, Inc. ( OTCQB : BMSN ) is a biotechnology company developing regenerative medicine therapies. The Company is focused on human therapies that address unmet medical needs. Specifically, Bio-Matrix Scientific Group Inc. is looking to increase the quality of life through therapies involving stem cell treatments. These treatments are focused in areas relating to cardiovascular, hematology, oncology and other indications.

Regen BioPharma, Inc., a subsidiary of Bio-Matrix Scientific Group, Inc. ( OTCQB : BMSN ), is a biotechnology company focused on identifying undervalued regenerative medicine patents in the stem cell space and rapidly advancing these technologies through pre-clinical and Phase I/ II clinical trials. To follow our development, visit us at http://www.regenbiopharma.com.

Disclaimer

This news release may contain forward-looking statements. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified. Future events and actual results could differ materially from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and uncertainties to which forward looking statements are subject include, but are not limited to, the effect of government regulation, competition and other material risks

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Bio-Matrix' Regen BioPharma Initiates Pre-Clinical Study in Support of HemaXellerate(TM) Cell Therapy

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NUI Galway to lead €6m research project into stem cell therapy for diabetes

The Irish Times - Monday, November 19, 2012

CLAIRE O'CONNELL

Could a particular type of adult stem cell offer a useful therapy for diabetes? An EU-funded project being led by NUI Galway hopes to find out.

The 6 million Reddstar project will assess whether the stem cells can tackle glucose levels and various complications of diabetes, including diabetic ulcers and eye, nerve, heart and kidney and bone damage.

The approach centres on a specific adult stem-cell population owned by Orbsen Therapeutics, a spin-out from the Science Foundation Ireland-funded Regenerative Medicine Institute (Remedi) at NUI Galway.

Initially, the project will develop ways to grow the bone-marrow-derived stem cells in a way that is useful for trials, according to company co-founder and Remedi director Prof Tim OBrien.

The cells will then be tested in several preclinical models of diabetic complications at centres in Galway, Belfast, Munich, Berlin and Porto.

Then the plan is to select one complication for which the adult stem cells will be assessed in human trials in Denmark.

The three-year EU funding will support nine jobs in Ireland, five of which will be in Orbsen Therapeutics, according to CEO Brian Molloy, who says the project should help to build Irelands status as a hub for cell therapy development and commercialisation.

Whilst wins such as the Reddstar programme are fantastic for us, we need to continue to develop and advance our product, he says.

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NUI Galway to lead €6m research project into stem cell therapy for diabetes

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The cell therapist

For Dr. Robert Janson-Mller, the science of fresh cell therapy is in his blood.

His grandfather, Dr. Philipp Janson was one of the few doctors who introduced the treatment in Germany. His father, Dr. Wolfgang Janson-Mller continued the work that was eventually passed on to him.

He was exposed to the revolutionary world of fresh cell therapy early on in life. The treatment uses live young cells from a donor animal like sheep to help regenerate damaged cells in the body. Dr. Mller practically grew up in his grandfather and father's clinic where he met the former's patients, some of whom still go to him for their regular treatments.

''A child always wants to grow up like his father and do the same thing. My father left it open for me. He told me I could do whatever I want, the same thing I am doing now for my daughter. I'm also head of a clinic in Munich. This is what I do besides cell treatment. We have a family practice. That is my main job,'' shares the 46-year-old German doctor who recently visited the Philippines to acquaint Filipinos with the science of fresh cell therapy.

Dr. Mller, who owns a fresh cell therapy laboratory and works as head doctor of Med Activ clinic in Munich, says that despite the growing market for it in America and Asia, there are only five doctors in Germany practicing the science. The treatment is known to deter degenerative diseases such as arthrosis, rheumatism and neurological disorders such as multiple sclerosis. But it is most popular as an anti-aging treatment. Recently, it has also been used to treat children with autism and Down syndrome.

Yet, Dr. Mller points out that fresh cell therapy is not a miracle cure for aging or these diseases. Some bodies accept the treatment while some don't. And, it doesn't treat every disease known to mankind.

Nevertheless, patients from all over the world still flock to his private clinic at the Prinzregent Hotel in Edenkoben, Germany to avail themselves of the treatment, which does not come cheap. One session would cost about $12,000 or R624,000.

''I don't treat patients with cancer, tuberculosis, AIDS, or those who are pregnant. We don't treat patients with acute inflammations like appendicitis. Aside from that, I need to see if it makes sense. If I don't see a possibility, I say no,'' he explains.

In this 60 Minutes interview, Dr. Mller shares how fresh cell therapy really works and how it can take more than just one, two, 20, 60 or even 100 treatments to get it right. Some may start as young as eight months old or continue the treatment at 99 years old. This just proves that a patient is never too young nor too old for this revolutionary treatment. (Angelo G. Garcia)

STUDENTS AND CAMPUSES BULLETIN (SCB): A lot of people are confused about the difference between stem cell and fresh cell therapy.

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The cell therapist

Recommendation and review posted by Bethany Smith

Icelandic Genetic Research Company Find Alzheimer’s Gene Variant

Icelandic genetic research company deCODE together with scientists from the Landsptali National University Hospital of Iceland and researchers in Holland, Germany and the United States have discovered a second gene variant to confer a high risk of acquiring the more common, late-onset of Alzheimers disease.

The variant was also found to predict poorer cognitive function in older individuals who do not have Alzheimers disease. The results of the research were published in the New English Journal of Medicine on Wednesday.

According to CEO of deCODE and lead author Kri Stefnsson, the results will provide new focus for drug development. The discovery of variant TREM2 is important because it confers high risk for Alzheimers and because the genes normal biological function has been shown to reduce immune response that may contribute to the disease. These combined factors make TREM2 an attractive target for drug development, he said.

The researchers obtained the genome sequences of 2,261 Icelanders and identified sequence variants that were likely to affect protein function.

ZR

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Icelandic Genetic Research Company Find Alzheimer’s Gene Variant

Recommendation and review posted by Bethany Smith


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