SCMOM 2012_Sistemic
Sistemic #39;s world leading expertise is on applying microRNA profiling in context with the biology, to areas where there is currently an unmet need for sophisticated tools delivering instructive and robust knowledge of the cell system. From their SistemQC trade; platform they have derived an extensive suite of tools for the cell therapy, gene therapy and bioprocessing community. SistemQC trade;, molecularly characterises cells including stem cells as well as aids in the optimization and monitoring (QC) of the manufacture process. More specifically the initial focus of SistemQC trade; by clients has been on generation of microRNA based ID markers, purity potency assessment and manufacture monitoring optimization. http://www.sistemic.co.uk Presenter: Jim Reid, Chairman and CEO, SistemicFrom:AllianceRegenMedViews:3 1ratingsTime:11:56More inScience Technology

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Gene Therapy against
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Episode 1. Uncovering Genetic Code
#12298;Unveiling the Secrets of Biotechnology #65306;Volume #8741; #12299; Part 1 #65306;Secrets Left by Our Ancestors Part 2 #65306;The Antidote to Rare Diseases -- Gene Therapy Part 3 #65306;Opening DNA #39;s Pandora #39;s BoxFrom:ccleestagViews:0 0ratingsTime:23:34More inScience Technology

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Gene Therapy - Wiki Article
Gene therapy is the use of DNA as a pharmaceutical agent to treat disease. It derives its name from the idea that DNA can be used to supplement or alter genes within an individual #39;s cells as a therap... Gene Therapy - Wiki Article - wikiplays.org Original @ http All Information Derived from Wikipedia using Creative Commons License: en.wikipedia.org Author: Unknown Image URL: en.wikipedia.org ( This work is in the Public Domain. )From:WikiPlaysViews:0 0ratingsTime:33:40More inEducation

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SCMOM 2012_NeoStem
NeoStem, Inc. is an emerging technology leader in the fast-developing cell therapy market. Its business strategy combines a state-of-the-art contract development and manufacturing subsidiary, Progenitor Cell Therapy, LLC, with a medically important cell therapy product development program. NeoStem #39;s most clinically advanced therapeutic, AMR-001, is being developed at its Amorcyte subsidiary, which is enrolling patients in a Phase 2 trial for preservation of heart function after a heart attack. Athelos Corporation, also a NeoStem subsidiary, is in early stage clinical exploration of a T-cell therapy for autoimmune conditions. Pre-clinical assets include our VSELTM Technology platform and our mesenchymal stem cell product candidate for regenerative medicine. http://www.neostem.com Presenter: Jonathan Sackner-Bernstein, NeoStem, Inc.From:AllianceRegenMedViews:4 1ratingsTime:14:54More inScience Technology

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SCMOM 2012_Regen BioPharma, Inc.
The Regen BioPharma business model is to take multiple stem cell therapeutics to and through the human "safety and signal of efficacy" stage (Phase I/II clinical trials). The approach is a highly focused analysis of issued patents in regenerative medicine, identification and acquisition of undervalued assets that have demonstrated proof of concept, and forming companies around these assets. Having assembled a core infrastructure specialized in obtaining regulatory approval and executing clinical trials in cell therapy, we aim to act as a "superincubator" that within 18 - 24 months grows technologies from laboratory to an asset ready for spin-off or sale to feed the pipeline of Big Pharma. http://www.regenbiopharma.com Presenter: J. Christopher Mizer, President, Regen BioPharma, Inc.From:AllianceRegenMedViews:4 1ratingsTime:09:13More inScience Technology

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Washington, November 28 (ANI): When mesenchymal cells derived from skeletal muscle (SM-MSCs) or adipose tissue (ADSCs) were injected into the heart muscle (myocardium) of separate groups of laboratory rats that had suffered a myocardial infarction, rats in both groups experienced significantly improved left ventricle function and smaller infarct size after cell therapy, a study has found.

The study, carried out by researchers at Oslo University Hospital and the Norwegian Center for Stem cell Research, Oslo University, sought to determine if MSCs from different organs would result in different functional outcomes.

"Despite advances in revascularization and medical therapy, acute myocardial infarction (AMI) and heart failure are still important causes of morbidity and mortality in industrialized countries," said study co-author Dr. Jan E. Brinchmann of the Norwegian center for Stem Cell Research at Oslo University Hospital, Oslo.

"AMI leads to a permanent loss of contractile elements in the heart and the formation of fibrous scarring. Regeneration of contractile myocardium has been a target of cell therapy for more than a decade," he added.

According to Dr. Brinchmann, MSCs tolerate hypoxia, secrete angiogenic factors and have been shown to improve vascularization; thus, they have properties suggesting that they may beneficially impact AMI, chronic heart failure and angina pectoris after cell transplantation.

Following injection into the "border zone" and infarct area of immunodeficient rats one week after induced myocardial infarction, the researchers used echocardiography to measure myocardial function and other analyses to measure the size of scaring, density of blood vessels in the scar, and the health of myocardial tissues.

"Our results showed that intramyocardial injection of both ADSCs and SM-MSCs one week after AMI led to a substantial decrease in infarct size and a significant improvement in left ventricle function when compared with injections of cell culture medium alone," concluded the researchers.

"There was a trend toward better functional improvement in the SM-MSC group when compared to the ADSC group, but this did not reach significance," they added.

They concluded that many questions remain unanswered, including the question of whether MSCs isolated from different organisms could result in different functional outcomes.

Other unanswered questions relate to the optimal time delay between the onset of myocardial infarction and injection of MSCs. These cells do, however, still appear to be "a potentially interesting adjuvant treatment modality for selected patients following acute myocardial infarction," they concluded.

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Public release date: 27-Nov-2012 [ | E-mail | Share ]

Contact: Robert Miranda cogcomm@aol.com Cell Transplantation Center of Excellence for Aging and Brain Repair

Putnam Valley, NY. (Nov. 27, 2012) A study published in the current issue of Cell Transplantation (21:8), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/, has found that when mesenchymal cells derived from skeletal muscle (SM-MSCs) or adipose tissue (ADSCs) were injected into the heart muscle (myocardium) of separate groups of laboratory rats that had suffered a myocardial infarction, rats in both groups experienced significantly improved left ventricle function and smaller infarct size after cell therapy.

The study, carried out by researchers at Oslo University Hospital and the Norwegian Center for Stem cell Research, Oslo University, sought to determine if MSCs from different organs would result in different functional outcomes.

"Despite advances in revascularization and medical therapy, acute myocardial infarction (AMI) and heart failure are still important causes of morbidity and mortality in industrialized countries," said study co-author Dr. Jan E. Brinchmann of the Norwegian center for Stem Cell Research at Oslo University Hospital, Oslo. "AMI leads to a permanent loss of contractile elements in the heart and the formation of fibrous scarring. Regeneration of contractile myocardium has been a target of cell therapy for more than a decade."

According to Dr. Brinchmann, MSCs tolerate hypoxia, secrete angiogenic factors and have been shown to improve vascularization; thus, they have properties suggesting that they may beneficially impact AMI, chronic heart failure and angina pectoris after cell transplantation. Following injection into the "border zone" and infarct area of immunodeficient rats one week after induced myocardial infarction, the researchers used echocardiography to measure myocardial function and other analyses to measure the size of scaring, density of blood vessels in the scar, and the health of myocardial tissues.

"Our results showed that intramyocardial injection of both ADSCs and SM-MSCs one week after AMI led to a substantial decrease in infarct size and a significant improvement in left ventricle function when compared with injections of cell culture medium alone," concluded the authors. "There was a trend toward better functional improvement in the SM-MSC group when compared to the ADSC group, but this did not reach significance."

They concluded that many questions remain unanswered, including the question of whether MSCs isolated from different organisms could result in different functional outcomes. Other unanswered questions relate to the optimal time delay between the onset of myocardial infarction and injection of MSCs. These cells do, however, still appear to be "a potentially interesting adjuvant treatment modality for selected patients following acute myocardial infarction," they concluded.

###

Contact: Dr. Jan E. Brinchmann, Norwegian Center for Stem Cell Research, Institute of Basic Medical Sciences, Oslo University Hospital Rikshospitalet and University of Oslo, PO Box 1121 Blindern 0317 Oslo, Norway. Tel. +42-22-84-04-89 Fax. +42-22- 85-10-58 Email: jan.brinchmann@rr.research.no

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PHILADELPHIA, Nov. 26, 2012 /PRNewswire/ --RRY Publications LLC today announced that the use of stem cell therapies in 2012 significantly exceeded forecasts which were originally presented at the February 2012 New York Stem Cell Summit. Said Robin Young, stem cell industry analyst and host of the New York meeting: "The range and scope of stem cell therapeutic use in the United States grew much faster than we'd forecasted earlier this year. Virtually all of the increases we're seeing are for adult stem cell therapies and, in particular, the use by physicians of both allograft and autologous stem cell products. It would not be an exaggeration to call this unexpected and remarkable growth."

Mr. Young's revised forecast of stem cell commercialization revenues for 2013-2020 will be presented at the February meeting in New York.

The companies, scientists and physicians that are at the forefront of this remarkable increase in stem cell therapeutic use will be presenting at the 8th Annual New York Stem Cell Summit. Listed below is the preliminary lineup of presenters for the 8th Annual Stem Cell Summit.

The Stem Cell Summit, an intensive one-day event, allows attendees to learn about the latest developments in the stem cell marketplace, evaluate the groundbreaking stem cell products physicians are using today, and discover the growing market potential in terms of revenues. For 2013, the Summit will feature 30+ presenters, a research review and debate session, and a special track on expanding the range of stem cell therapies.

The 8th Annual Stem Cell Summit will take place on Feb. 19, 2013, at Bridgewaters in the heart of New York City's historic South Street Seaport. The preliminary roster of companies featured will include representatives from 2012 presenters and new 2013 presenters.

Aastrom Biosciences, Inc.

Advanced Cell Technology

Aldagen, Inc.

AllCells, LLC.

Aruna Biomedical, Inc.

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First Annual Research Day
On November 15, 2012, the Biomedical Research Institute (BRI) at Brigham and Women #39;s Hospital held its first Research Day. The event featured 150 poster presentations by leading BWH researchers on today #39;s hottest health topics such as obesity, healthy aging and personalized medicine. Dr. Robert C. Green was named the winner of the $100000 BRIght Futures Prize, after a unique competition in which nearly 6500 online votes from people across the globe determined the winning project. Dr. Green #39;s project explores the use of genome sequencing in newborns. The other BRIght Futures finalists included a project jointly led by Drs. Phil DeJager and Elizabeth Karlson, whose proposal focused on using genetics and electronic health records to treat multiple sclerosis and a project led by Dr. Robert Plenge, whose proposal focused on the use of technology to unravel the mysteries of the immune system.From:BrighamandwomensViews:3 0ratingsTime:03:47More inNonprofits Activism

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The Back Up Singers "Something Inside So Strong"
Make a donation today to see the video in full: uk.virginmoneygiving.com A group of British legal professionals have swapped the courtroom for the recording studio in a bid to raise vital funds for Back Up. #39;The Back Up Singers #39;, as they are known, met in 2011 at a networking event and decided to form a choir to show the lighter side of their profession and to highlight the distressing psychological effects of spinal cord injury.From:BackUpTrustViews:111 2ratingsTime:01:16More inNonprofits Activism

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Holiday Message from Mary Fran Menge
"I would not be walking today had it not been for Mary Free Bed," says patient Mary Fran Menge of L #39;Anse, MI. In 2009, Mary was in an automobile accident that left her with a severe spinal cord injury. With the help of robotic-assisted therapy and a lot of determination, Mary is now able to walk.From:MaryFreeBedViews:141 0ratingsTime:00:45More inEducation

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Public Forum on Clinical Trials in Spinal Cord Injury 2012
The Public Forum on Clinical Trials in Spinal Cord Injury offered an opportunity to learn about spinal cord research advances in "lay" language from leading international spinal cord scientists.From:WesternUniversityViews:9 0ratingsTime:01:01:24More inEducation

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Dr. Sasha Rabchevsky - J. Allyn Taylor International Prize in Medicine Symposium 2012
Sasha Rabchevsky, PhD, Associate Professor of Physiology, Spinal Cord Brain Injury Research Center (SCoBIRC), University of Kentucky, Lexington, KY. Modulation of intraspinal plasticity associated with autonomic dysreflexia after complete spinal cord injury.From:WesternUniversityViews:9 0ratingsTime:48:17More inEducation

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RIP Scripps Ranch Motorcross Racer - Jantz Grodzicki Dies After Crash
RIP Bravery Jantz GrodzickI - MX For Life This is Chris, Jantz #39;s dad... I wanted to first thank everyone for the heartfelt prayers for Jantz. I need to ask everyone the favor of including Jantz in your prayers as we move through this painful journey. Jantz sustained a devastating brain cell and spinal cord injury. He was wearing a layete brace and shoei helmet. We left the hospital last night with zero hope from the doctors of his survival chances. His heart stopped at the track and he was pronounced brain dead at the hospital with no response. He was however put on life support until we decided on the options available that I hope none if you ever half to face. A short while ago we received a call from the doctor that a miracle took place this morning at 6:30am that Jantz #39;s "condition has changed significantly" he is responding to eye commands, left to right, up and down and raise your eyebrows. Still no other responses other than this. Given what we were told this is truly a miracle. The thoughts and prayers shared here and on Facebook are what have helped him to make a move off the line. The race for recovery is just beginning and we can only pray that God will pull him through. May god bless each of you and your families. The Grodzicki Family.... Scripps Ranch motocross racer, Jantz Grodzicki, dies after crash. Friends and family are mourning the loss of a local teen motocross racer who died after a racing crash in Florida.From:xBadBoyZz ClanViews:1424 10ratingsTime:01:03More inAutos Vehicles

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How I Recovered Bladder Function After A Spinal Cord Injury
Molly Hale speaks of the ideas she used to recover her bladder function after a spinal cord injury.From:abilityproductionViews:0 1ratingsTime:14:14More inEducation

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Ekso Bionics #39; Lyne Vale: Full talk and live exoskeleton demo at Wired 2012
Full story: http://www.wired.co.uk Lynn Vale is a physiotherapist specialising in neurology, spinal cord injuries and rehabilitation. Working at Ekso Bionics, Vale helps spinal cord injury patients and people with other neurological disorders to walk again with the help of their exoskeleton, the Ekso. Formed in 2005 as Berkeley ExoWorks, the group began revolutionising the field of bionic exoskeletons to augment human mobility and capability. It #39;s first models of exoskeleton legs allowed users to carry huge loads up slopes and stairs, aiding hikers and soldiers in lifting work. In 2011 the group became Ekso Bionics, producing exoskeletons to help people with serious injuries and neurological disorders to walk. Ekso Bionics have worked with well over three hundred patients and dozens of clinicians and researchers to understand how to apply these technical breakthroughs to the advancement of human motion. Ekso was demonstrated live at Wired 2012.From:WiredVideoUKViews:398 2ratingsTime:16:17More inScience Technology

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Mobile Music Touch Glove
The Mobile Music Touch glove, designed and manufactured at Georgia Tech as part of a research project, teaches the wearer simple piano melodies without their active attention. Early studies suggest that the MMT glove may also help people with tetraplegia due to partial spinal cord injury improve the sensation in their hands.From:Thad StarnerViews:0 0ratingsTime:01:39More inScience Technology

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Rehabilitation Hospital of Southern New Mexico
http://www.dexknows.com If youre in need of high quality healthcare, then turn to the well trained professionals at Rehabilitation Hospital of Southern New Mexico! Located in Las Cruces, we provide the surrounding communities with a wide range of inpatient programs, like stroke, spinal cord injury, and neurological disorders. Were here to care for you!From:dex knowsvideoViews:0 0ratingsTime:00:31More inAutos Vehicles

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How To - Do Arms Exercises Using Wrist Weights for C5-C6 Tetraplegia
Myron Wand has a spinal cord injury (C5-C6 Tetraplegia). Here he shows some tips and techniques to do arms exercises using wrist weights.From:HealthyTomorrowViews:1 0ratingsTime:02:26More inSports

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Crash - Scipps Motorcross Racer Dies - Jantz Grodzicki RIP
Mx for life prayforjantz grodzicki buy t-shirts support family RIP Bravery Jantz GrodzickI - MX For Life Bad Jantz grodzicki crash 2012 dies scripps racer ranch dies 2012 cbc news This is Chris, Jantz #39;s dad... I wanted to first thank everyone for the heartfelt prayers for Jantz. I need to ask everyone the favor of including Jantz in your prayers as we move through this painful journey. Jantz sustained a devastating brain cell and spinal cord injury. He was wearing a layete brace and shoei helmet. We left the hospital last night with zero hope from the doctors of his survival chances. His heart stopped at the track and he was pronounced brain dead at the hospital with no response. He was however put on life support until we decided on the options available that I hope none if you ever half to face. A short while ago we received a call from the doctor that a miracle took place this morning at 6:30am that Jantz #39;s "condition has changed significantly" he is responding to eye commands, left to right, up and down and raise your eyebrows. Still no other responses other than this. Given what we were told this is truly a miracle. The thoughts and prayers shared here and on Facebook are what have helped him to make a move off the line. The race for recovery is just beginning and we can only pray that God will pull him through. May god bless each of you and your families. The Grodzicki Family.... Jantz grodzicki crash caught on tape 2012 MX for life my friendFrom:huntghostsViews:80 1ratingsTime:01:03More inAutos Vehicles

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SCMOM 2012_Owl Biomedical
Owl biomedical is an emerging company commercializing an innovative high-speed, disposable cartridge-based cell sorting platform called the Nanosorter. The Nanosorter enables rapid processing of large numbers of cells safely without aerosols and in a simple, readily deployable and easy to use system. The Nanosorter platform uniquely combines the world #39;s fastest microvalve (fabricated within a microchip) and the well-proven principles of fluorescence-activated sorting of cells. Cells purified using the Nanosorter can be employed for a wide variety of commercial applications, including: adoptive immunotherapy for treatment of cancer, stem cell therapies for regenerative medicine (eg stroke, limb ischemia, wound healing), cell-based cancer diagnostics, and a wide variety of cell-based applied research applications. Owl biomedical was founded in 2011 and is based in Santa Barbara, California. http://www.owlbiomedical.com Presenter: Jim Linton, Ph.D., MBA, President and Chief Business Officer, Owl BiomedicalFrom:AllianceRegenMedViews:7 1ratingsTime:15:31More inScience Technology

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SCMOM 2012_UC Davis - Wheelock
UC Davis is playing a leading role in regenerative medicine, with nearly 150 scientists working on a variety of stem cell-related research projects at campus locations in both Davis and Sacramento. The UC Davis Institute for Regenerative Cures, a facility supported by the California Institute for Regenerative Medicine (CIRM), opened in 2010 on the Sacramento campus. This $62 million facility is the university #39;s hub for stem cell science. It includes Northern California #39;s largest academic Good Manufacturing Practice laboratory, with state-of-the-art equipment and manufacturing rooms for cellular and gene therapies. UC Davis also has a Translational Human Embryonic Stem Cell Shared Research Facility in Davis and a collaborative partnership with the Institute for Pediatric Regenerative Medicine at Shriners Hospital for Children Northern California. All of the programs and facilities complement the university #39;s Clinical and Translational Science Center, and focus on turning stem cells into cures. http://www.ucdmc.ucdavis.edu/stemcellresearch Presenter: Vicki L. Wheelock, MD, Clinical Professor, Neurology, Director, HDSA Center of Excellence, Principle Investigator, CIRM Grant DR2A-05415, UC Davis Health SystemFrom:AllianceRegenMedViews:1 0ratingsTime:12:18More inScience Technology

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SCMOM 2012_Cedars-Sinai Regenerative Medicine Institute
The Cedars-Sinai Regenerative Medicine Institute (RMI) brings together research faculty and clinicians to provide a true "bench to bedside" organization. We have five major programs of research: (i) Brain, (ii) Eye, (iii) Pancreas and Liver, (iv) Blood and (v) Skeletal. Working within each of these programs benefits from our core facilities with a focus on generating induced pluripotent stem cells from adult human skin samples and optimizing differentiation into various tissues of the human body of interest to the six programs. The pluripotent cells are used to both increase our understanding of human diseases through modeling, and provide a foundation for pre-clinical studies aimed at establishing and validating cellular therapeutic approaches to human illness. http://www.cedars-sinai.edu/Research-and-Education/Institutes/Regenerative-Medicine-Institute Presenter: Clive Svendsen, Ph.D., Director, Cedars-Sinai Regenerative Medicine InstituteFrom:AllianceRegenMedViews:1 0ratingsTime:13:27More inScience Technology

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SCMOM 2012_CIRM
Morrie Ruffin, Managing Director, Alliance for Regenerative Medicine Jonathan Thomas, Ph.D., JD, Chair, Governing Board, CIRM (Independent Citizens Oversight Committee)From:AllianceRegenMedViews:2 1ratingsTime:22:41More inScience Technology

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