UK Man has Prostate Removed After Tests Reveal 'Jolie' Gene Flaw

Posted: May 19, 2013 at 1:43 pm

Angelina Jolie has revealed she underwent a double masectomy when tests revealed genes associated with breast cancer

A 53-year-old British father has become the first man to have his prostate removed because tests revealed he was carrying a "faulty" cancer gene.

A clinical trial at London's Institute of Cancer Research revealed that he carried the BRCA2 gene, which research shows is associated with a high risk of developing prostate cancer.

Several of the man's family had suffered from breast or prostate cancer, which is why he took part in the study.

The closely associated BRCA1 gene has been known for some time to have links with breast cancer, and last week actress Angelina Jolie revealed that she had undergone a double mastectomy when tests revealed that she carried the gene.

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After receiving the news the man asked doctors to remove his prostate, which tests had shown to be healthy.

Surgeons were initially reluctant, since the potential side effects of the operation include infertility, incontinence and sexual dysfunction.

MRI scans and a prostate-specific antigen, or PSA tests, did not show the presence of malignant cells, but microscopic examination revealed cell changes associated with cancer, prompting the surgeons to act.

Surgeon Roger Kirby told the Sunday Times: "The relatively low level of cancerous cells we found in this man's prostate before the operation would these days not normally prompt immediate surgery to remove the gland, but given what we now know about the nature of BRCA2, it was definitely the right thing for this patient."

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UK Man has Prostate Removed After Tests Reveal 'Jolie' Gene Flaw

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