Scientists find new genetic test predicts prostate cancer risk

Posted: July 28, 2012 at 3:14 am

By Lynne Friedmann

A genetic test to predict the risk for prostate cancer could reduce the need for repeat biopsies in men who have previously had negative biopsies.

In a clinical trial, 1,654 men who had prostate biopsies also had genetic studies conducted that looked for the presence of genetic variations that may have an association with prostate cancer risk.

The genetic test outperformed the widely used PSA (Prostate-Specific Antigen) test in assessing cancer risk. Because this genetic score is available at any time in a mans lifetime it could be used as a pre-screening test thus leaving aggressive PSA screening only to men at higher genetic risk.

The goal is to avoid, particularly in older men, unnecessary repeat biopsy procedures which carry with them the risk of infection and potential hospitalizations.

Findings appear in the journal of European Urology.

News release at

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Scientists find new genetic test predicts prostate cancer risk

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