New ovarian cancer gene found in mice

Posted: September 6, 2013 at 5:41 am

Editor's Choice Academic Journal Main Category: Ovarian Cancer Also Included In: Cancer / Oncology Article Date: 05 Sep 2013 - 3:00 PDT

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Cancer Research UK scientists have discovered a gene that repairs damaged DNA is also linked to ovarian cancer in mice. They say if the gene - known as Helq - is faulty or missing, DNA errors accumulate as cells multiply, and this raises the chance of developing the cancer.

They write about their findings in the September 4th online issue of Nature.

According to the American Cancer Society (ACS), ovarian cancer accounts for about 3% of cancers among women, but it is responsible for more deaths than any other cancer of the female reproductive system.

The ACS estimates that in 2013, around 22,240 women in the US will discover they have ovarian cancer, and 14,030 will die of the disease.

In the UK, every year around 7,000 women are diagnosed with ovarian cancer, and about 4,300 die from it, according to figures from Cancer Research UK.

The main reason for the high numbers of deaths relative to new cases is because ovarian cancer is hard to diagnose early and treat successfully.

Dr. Julie Sharp, the senior science information manager at Cancer Research UK says:

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New ovarian cancer gene found in mice

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