Public release date: 8-Feb-2013 [ | E-mail | Share ]

Contact: Phyllis Edelman pedelman@genetics-gsa.org 301-634-7302 Genetics Society of America

Bethesda, MDFebruary 8, 2013 Listed below are the selected highlights for the February 2013 issue of the Genetics Society of America's journal, Genetics. The February issue is available online at http://www.genetics.org/content/current. Please credit Genetics, Vol. 193, February 2013, Copyright 2013.

Please feel free to forward to colleagues who may be interested in these articles on population and evolutionary genetics; gene expression; genome and systems biology; and methods, technology and resources.

ISSUE HIGHLIGHTS

Population and Evolutionary Genetics Patterns of transcriptome divergence in the male accessory gland of two closely related species of field crickets, pp. 501-513 Jose A. Andrs, Erica L. Larson, Steven M. Bogdanowicz, and Richard G. Harrison

What kinds of genetic changes are responsible for the origin of species? What forces drive evolution of "speciation genes"? Answers to these fundamental questions may be found by examining patterns of genomic differentiation between closely related species. The authors have compared transcriptomes of two field crickets to identify candidate gene regions that contribute to reproductive isolation and to assess the role of selection in divergence of genes encoding seminal fluid proteins.

Methods, Technology and Resources Captured segment exchange: A strategy for custom engineering large genomic regions in Drosophila melanogaster, pp. 421-430 Jack R. Bateman, Michael F. Palopoli, Sarah T. Dale, Jennifer E. Stauffer, Anita L. Shah, Justine E. Johnson, Conor W. Walsh, Hanna Flaten ,and Christine M. Parsons and Long-range targeted manipulation of the Drosophila genome by site-specific integration and recombinational resolution, pp. 411-419 Natalia Wesolowska and Yikang S. Rong

This issue of Genetics features two articles that describe significant improvements in the Drosophila genetic toolbox (see Commentary by Crown and Sekelsky). Wesolowska and Rong describe an approach for targeted manipulation of the genome that promises to render all Drosophila genes amenable to systematic targeted mutagenesis. Bateman et al. offer a novel approach for swapping large segments of the genome with engineered DNA, permitting custom alterations to any genomic region. And last month Staller and Perrimon and colleagues presented a powerful, simple method for depleting gene function in early embryos with short hairpin RNAs.

Population and Evolutionary Genetics Evolutionary rate covariation in meiotic proteins results from fluctuating evolutionary pressure in yeasts and mammals, pp. 529-538 Nathan L. Clark, Eric Alani, and Charles F. Aquadro

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Genetics Society of America's Genetics journal highlights for February 2013

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