Dr. Jeffrey Myers Explains Genetic Variations in Head and Neck Cancer

Posted: September 25, 2011 at 3:39 am



bit.ly The first comprehensive studies of genetic variation in head and neck squamous cell cancers have uncovered mutations that may help refine treatment for patients with the disease, according to researchers at The University of Texas MD Anderson Cancer Center. The two multi-institutional studies, both published online on the Science Express feature of the journal Science, found: • Mutations that affect an unexpected tumor-suppressing role of the NOTCH1 gene; • Infrequent but significant mutations in four suspected cancer-causing genes; and • Frequent mutation of the tumor-suppressing gene p53, which previously was known to be damaged or impaired in head and neck cancer. "These findings should help us better treat patients by allowing us to take a more personalized approach than is currently possible with this cancer," said Jeffrey Myers, MD, Ph.D., professor in MD Anderson's Department of Head and Neck Surgery and co-senior author of one of the papers.

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Dr. Jeffrey Myers Explains Genetic Variations in Head and Neck Cancer

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