Do disruptions in brain communication have a role in autism?

Posted: March 21, 2013 at 11:47 am

Public release date: 21-Mar-2013 [ | E-mail | Share ]

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 x2156 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, March 21, 2013A new study of patterns of brain communication in toddlers with autism shows evidence of aberrant neural communication even at this relatively early stage of brain development. The results are presented in an article in Brain Connectivity, a bimonthly peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Brain Connectivity website at http://www.liebertpub.com/brain.

A team of researchers from The Netherlands (University Medical Center Utrecht and Utrecht University, Radboud University Nijmegen Medical Center, and VU University Medical Center, Amsterdam) compared electroencephalography (EEG) recordings from young children with and without autism. The researchers evaluated the patterns of communication between various functional neural networks in the brain that aid in the processing and integration of information.

In the article "Disrupted Functional Brain Networks in Autistic Toddlers," Maria Boersma et al. describe significant differences in the communication patterns, in particular in variables such as path length and clustering.

"This work provides support to the hypothesis that autism is a disorder of connectivity," says Christopher Pawela, PhD, Co-Editor-in-Chief and Assistant Professor, Medical College of Wisconsin. "The researchers demonstrated that autistic children's brains have both reduced brain connectivity and a diminished capacity for neural communication. This is an interesting finding and has impact on the understanding of the abnormal brain development in autistic children."

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About the Journal

Brain Connectivity is the journal of record for researchers and clinicians interested in all aspects of brain connectivity. The Journal is under the leadership of Founding and Co-Editors-in-Chief Christopher Pawela, PhD and Bharat Biswal, PhD, Associate Professor, University of Medicine and Dentistry of New Jersey. It includes original peer-reviewed papers, review articles, point-counterpoint discussions on controversies in the field, and a product/technology review section. To ensure that scientific findings are rapidly disseminated, articles are published Instant Online within 72 hours of acceptance, with fully typeset, fast-track publication within four weeks. Tables of content and a sample issue can be viewed on the Brain Connectivity website at http://www.liebertpub.com/brain.

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Do disruptions in brain communication have a role in autism?

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