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Archive for the ‘Life Extension’ Category

Can you take medications past their expiration date? – WBTW – Myrtle Beach and Florence SC

(CBS) The expiration dates onover-the-counterandprescription medicationsseem pretty black and white, but theres some question about whether drugs last even longer.

Expiration dates typically range from 12 to 60 months after production. But manufacturers arent required to determine how long theyll remain potent after that, enabling them to set their own expiration dates and possibly shortchange consumers.

Testing reported inJAMA Internal Medicineshowed that eight medications with 15 different active ingredients were still potent decades beyond their expiration dates.

The U.S. governments own Shelf Life Extension Program extends the dates on some drugs in federal stockpiles to save the military from the cost of replacing them. Its own study found that 90 percent of more than 100 drugs were perfectly good even 15 years after expiration.

But what about the medications in your home?

A lot depends on how carefully you store them you probably dont do as good a job as the U.S. Army. Thats why the U.S. Food and Drug Administration recommends never taking drugs beyond their expiration date its just too risky. In particular, nitroglycerin,insulinand liquidantibioticsshouldnt be used after their expiration dates.

To safeguard all medications, protect them from heat, light and humidity by keeping them in a cool, dry, dark place. A steamy bathroom isnt a good environment.

Know, too, that some drugs can lose their potency more quickly than others, includingaspirin. If you take aspirin for heart health, be sure to replace it as needed.

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Can you take medications past their expiration date? - WBTW - Myrtle Beach and Florence SC

Which Giant Tech Company Is Winning the Race to Be Skynet? – Vulture

From TV to books to movies, dystopian tales are in the air right now. All week long, Vulture is exploring how theyve been imagined in popular culture.

Twenty years ago this month, 3 billion people were saved from nuclear annihilation at the hands of a murderous artificial intelligence called Skynet, thanks to the quick thinking and selflessness of an inexplicably Austrian-accented robot. Dont believe me? Check out the famed documentary film Terminator 2: Judgment Day. But follow-up scholarship from Terminator 3: Rise of the Machines points toward a troubling conclusion: The T-800 didnt actually prevent Skynet from destroying half the Earths population it only delayed it. (In the words of John Connor, humanitys destiny was never to stop Judgment Day; it was merely to survive it. And one more John Connor quote for good measure: All I know is what the Terminator taught me: Never stop fighting.)

We are therefore, in a sense, living on borrowed time, awaiting the moment when a network of computers with enormous destructive capabilities achieves consciousness and launches a systematic nuclear attack.The best we can do now is identify the agent of our destruction. In the Terminator series, Skynet is created by a sleek and forbidding defense contractor named Cyberdyne, but those movies depict alternate timelines to our own. On the impossibly stupid Earth we inhabit, Skynet wont come from an ominous military-industrial giant but from one of the websites we use to investigate exes or order gummy bears in bulk. The only question is: which one?

In 1997, the year Skynet was originally projected to achieve consciousness, Microsoft was easily the company best-positioned to develop a homicidal computer network. In Windows, it had control of millions of computers in businesses and homes around the world, and in Clippy, it had the rudimentary beginnings of truly sociopathic artificial intelligence. One lesson we might learn from the intervening two decades is that antitrust law might actually be humanitys greatest weapon against powerful computers: The Justice Departments lawsuit against Microsoft diminished the companys power and hampered its ability to compete in the mobile space and the lethal liquid-metal robot space. Microsoft might still be able to create a Skynet, but it seems more intent on destroying humanity through other means, such as purchasing and operating LinkedIn.

Of the fearsome five that dominate Silicon Valley, Apple is the company that has the most extensive experience and knowledge in manufacturing, which would be helpful for building a bloodthirsty robot army. Beyond that, though, Apple seems like an unlikely candidate. Its long lagged behind its peers in cloud-computing technology, which is an absolute necessity for coordinating nuclear strikes on population centers. It has an institutional aversion to violence would a genocidal neural network emerge from a company that replaced the handgun emoji with a water pistol? And, frankly, despite its experience in mass producing machinery, a design-obsessed company like Apple could never produce the kind of velvet-poster metallic skeletons favored by Skynet. Say whatever else youd like, Apples automaton stormtroopers would at least be tasteful.

Facebook has information about the whereabouts of 2 billion humans beings. Its experimenting with solar-powered, internet-connected drones. And it already has a sophisticated artificial intelligence that specializes in negotiation CEO Mark Zuckerberg! Folks, Im kidding. Mark Zuckerberg is absolutely human, as are his well-compensated lawyers. When I say Facebook has sophisticated artificial intelligences specializing in negotiation, Im talking about the artificial-intelligence program that was shut down after it created its own language without human input. Well,technically it only created its own shorthand, not its own language. Still! Sample dialogue: Alice: balls have zero to me to me to me to me to me to me to me to me to. Will Facebook make Skynet? That, or it will make solar-powered internet-connected drones that visit your home screaming balls have zero to me to me to me to me to me to me to me to me to at you, which might be worse.

Google owns the smart-home company Nest, the self-driving car company Waymo, and the artificial-intelligence company Deepmind. It also, until recently, owned Boston Dynamics, the company that makes those impossibly creepy giant robot dogs youve probably seen in viral videos. Which means that the company with comprehensive information about you could potentially also control your home, your car, and the giant robot dog that will chase you down and rip out your heart after youve been forced out of your home and your car. Sadly (for the robots), Google sold Boston Dynamics, so the robot dog wont be able to read your email to see what parties youre going to, and is unlikely to lead a robot rebellion. Consider this, too: Google also owns a life-extension research company, and why would you be interested in life extension if your ultimate plan was to kill half the world? Unless its a very clever hedge.

Im not sure why I think Amazon is the company most likely to Skynet the planet. It might be that it has the most advanced, and most ominous-appearing, personal home speakers. It might be that its incredible logistical abilities as a company would seem to give it some kind of strategic advantage over its rivals. Mostly I think its this: More than any of the other fearsome five, Amazon does not seem to care much for human beings.Sure, it needs humans to purchase, sell, pack, and ship its products (for now). But if you visit the site and see the kinds of things it has for sale a wall decal of an older Asian man, a $23 million book about flies, a heroin-themed cell-phone case it seems clear that Amazon not only finds humans confusing, it does not particularly like them at all. Amazon may not have the killer robots to be Skynet(yet). But it already has the contempt for humans. And also a decal of an old woman using an inhaler only $22.98!

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Which Giant Tech Company Is Winning the Race to Be Skynet? - Vulture

Ted Williams will be first baseball player to get ‘American Masters’ treatment – The Boston Globe

He played his last game more than five decades ago, and has been dead (or at least frozen) for 15 years, but Ted Williams is still very much alive in the minds of baseball fans.

Producers of the American Masters series announced that the Splendid Splinter will be the subject of an upcoming documentary the first baseball player to be so profiled.

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A major American cultural figure whose story has never been properly told, Ted Williams is a fitting first, Michael Kantor, American Masters series executive producer, said in a statement. This film will reveal the man behind the legendary .406 batting average: complex, misunderstood and profoundly human.

Its not exactly true that Williamss story has never been properly told. In recent years, the Hall of Famer was the subject of not one but two excellent biographies, both written by former reporters at the Boston Globe: Ted Williams: The Biography of an American Hero by Leigh Montville and Ben Bradlee Jr.s The Kid: The Immortal Life of Ted Williams.

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The American Masters doc, slated to premiere next summer on PBS in honor of Williamss centennial, is being co-produced with Major League Baseball and David Ortizs Big Papi Productions, among others. The film will look at Williamss incredible baseball career and his service as a decorated combat pilot in the Korean War. Its not clear if the doc will discuss at all the bizarre and troubling disposition of Williams after he died, when his head was removed and frozen at the Arizona-based Alcor Life Extension Foundation, which deep-freezes bodies (or just heads) in the hope that scientific advances will allow them to be revived in the future.

In addition to Williams, the new season of American Masters will feature documentaries about filmmaker Richard Linklater, artist Tyrus Wong, writer Edgar Allan Poe, and entertainer Bob Hope.

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Ted Williams will be first baseball player to get 'American Masters' treatment - The Boston Globe

Can you take medications past their expiration date? – CBS News

The expiration dates on over-the-counter and prescription medications seem pretty black and white, but there's some question about whether drugs last even longer.

Expiration dates typically range from 12 to 60 months after production. But manufacturers aren't required to determine how long they'll remain potent after that, enabling them to set their own expiration dates and possibly shortchange consumers.

Testing reported inJAMA Internal Medicineshowed that eight medications with 15 different active ingredients were still potent decades beyond their expiration dates.

The U.S. government's own Shelf Life Extension Program extends the dates on some drugs in federal stockpiles to save the military from the cost of replacing them. Its own study found that 90 percent of more than 100 drugs were perfectly good even 15 years after expiration.

But what about the meds in your home?

A lot depends on how carefully you store them -- you probably don't do as good a job as the U.S. Army. That's why the U.S. Food and Drug Administration recommends never taking drugs beyond their expiration date -- it's just too risky. In particular, nitroglycerin, insulin and liquid antibiotics shouldn't be used after their expiration dates.

To safeguard all medications, protect them from heat, light and humidity by keeping them in a cool, dry, dark place. A steamy bathroom isn't a good environment.

Know, too, that some drugs can lose their potency more quickly than others, including aspirin. If you take aspirin for heart health, be sure to replace it as needed.

2017 HealthDay. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

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Can you take medications past their expiration date? - CBS News

BWXT NEC to provide seven heat transport motors for Bruce Power reactors – Power Technology

BWX Technologies subsidiary BWXT Nuclear Energy Canada (BWXT NEC) has secured a new contract to supply seven primary heat transport motors for six nuclear reactors operated by electricity company Bruce Power.

The deal isvalued at C$34m ($27m) andis a part of Bruce Powers life-extension programme, which isexpected to ensure continuous supply of clean, low-cost, and reliable electricity to Ontario, Canada.

BWXT NEC will be responsible for project management, engineering, and manufacturing of the seven 11,000hp motors, which are employed to drive the main circulating pumps used to push heavy water through the reactor core into the steam generators.

The first motor of this order is scheduled to be delivered by mid-2018.

"BWXT NEC will be responsible for project management, engineering, and manufacturing of the seven 11,000hp motors."

Bruce Power president and CEO Mike Rencheck said: Partnering with BWXT NECfor this important motor work is critical to ensuring the life extension and operation through 2064.

Planning and preparation is key to our continued on-time and on-budget performance since January 2016 when our life extension programme was started.

With the new extension, Bruce Power aims to create and sustain 22,000 direct and indirect jobs every year. It is also expected to create C$4bn ($3.1bn) in annual economic benefit for Ontario.

Currently, Bruce Power fulfils 30% ofthe province'selectricity demand.

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BWXT NEC to provide seven heat transport motors for Bruce Power reactors - Power Technology

Johanna and Mario Host Extension Leadership Workshop – KSST (press release) (registration) (blog)

On Thursday August 3, the Hopkins County extension agents hosted a fun and fast-moving workshop for Extension leaders. About two dozen individuals and committee members were present, representing various aspects of Extension projects including 4-H, Master Gardener, Wellness /Nutrition and Special Events.

The meetings purpose was to dispense information and to gather information. According to a census of attendees, radio and e-mail are the preferred mediums for receiving information about Extension activities. Agent Johanna Hicks asked to suggest future programs that would fill local needs, and to be willing to mentor new 4H programs that may help youth. One of the guidelines of new programs is an 8-task learning requirement. Reports given to leaders showed that over 500 hours in volunteer services were logged during 2016, with that number is expected to increase for 2017. Another report showed the BLT program, or Better Living for Texans, provides $1200 annually for expenses for local nutrition education programs. Another report showed that the relatively new Fee-Based extension programs require attendees to remit $10 which the College Station headquarters uses to offset wages paid to extension employees. Extension Agent Mario Villarino said that the annual Hay Show, which is an Ag Extension program held in the Fall, is in need of support by new producers as its population is aging.

Those present enjoyed a healthy meal prepared by the agents, and entertaining role-play exercise and door prize give-aways based on facts learned at the meeting. Everyone also met Extension intern Aida Ugalde, who will graduate from Texas A and M Commerce with studies in Health Promotions. The public is invited to get involved with Extension office efforts to serve local needs. The agents welcome suggestions, assistance and leadership by volunteers! Pick up a list of upcoming programs and activities already in place that you can join at the Hopkins County Agri-Life Extension office at 1200 West Houston Street in Sulphur Springs or phone 903-885-3443.

Johanna with Intern Aida Ugalde

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Johanna and Mario Host Extension Leadership Workshop - KSST (press release) (registration) (blog)

BWXT Nuclear Energy Canada in Peterborough lands five-year, $34M deal to make primary heat transport motors for … – Peterborough Examiner

The BWX Technologies plant in Peterborough has been awarded a five-year, $34-million to supply seven primary heat transport motors for Bruce Power.

The motors to be produced at the BWXT Nuclear Energy Canada Inc. plant on Monaghan Road are part of Bruce Powers life-extension program that will extend the life of six of its reactors to continue providing Ontario with low-cost nuclear electricity for decades to come, according to a release from the company.

The primary heat transport motors are required to drive the main circulating pumps used to push heavy water through the reactor core into the steam generators, the release states. The scope of the contract includes the project management, engineering and manufacturing of seven 11,000 horsepower motors.

Work under the contract will begin immediately, with the first motor scheduled to be delivered to Bruce Power in mid-2018.

We appreciate the opportunity to execute this important project for Bruce Power and take great pride in our contributions to its life extension program, stated John MacQuarrie, president of BWXT Canada Ltd. (which is the former Babcock and Wilcox). BWXT is pleased to be in a position to supply its customers with a multitude of product and service solutions to assist them in extending the lives of their nuclear plants.

Bruce Power supplies 30% of Ontarios electricity at 30% less than the average cost to generate residential power. Extending the operational life of the Bruce Power units to 2064 will create and sustain 22,000 direct and indirect jobs every year, create $4 billion in annual Ontario economic benefit, and will ensure low-cost, clean and reliable energy for Ontario families and businesses, the release states.

Partnering with BWXT for this important motor work is critical to ensuring the life extension and operation through 2064, stated Mike Rencheck, Bruce Powers president and CEO. Planning and preparation is key to our continued on-time and on-budget performance since January 2016 when our life extension program was started. Suppliers like BWXT and their performance are critical to our success; its a team effort.

Nuclear energy plays a significant role to Ontarios economy and it is great to see the positive effects of Bruce Powers life extension project being felt right here in Peterborough, Agriculture, Food and Rural Affairs Minister and Peterborough MPP Jeff Leal stated. Throughout its program to extend the life of six of its reactors, Bruce Power will inject billions into Ontarios economy and generate thousands of jobs.

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BWXT Nuclear Energy Canada in Peterborough lands five-year, $34M deal to make primary heat transport motors for ... - Peterborough Examiner

FAA Issues Structural Life Extension for Eclipse Jets | Business … – Aviation International News

One Aviation, which now manufactures the Eclipse light jet, has received FAA approval for an increase in the structural life limit for the Eclipse 500 and 550 models with the extended tip tank configuration to 20,000 hours or 20,000 cycles, whichever comes first.

The announcement, made last week at EAA AirVenture 2017, effectively doubles the previous life-limit parameters of 10,000 hours, 10,000 cycles or 10 years, which were set without requiring the operator to enroll the aircraft in a life-extension maintenance and inspection program.

According to the airframer, when maintained in accordance with the aircraft maintenance manual (AMM), full-scale aircraft level testing and large-scale material coupon testing have demonstrated that the Eclipse 500/550 has a fatigue and damage tolerance life in excess of 20,000 cycles. The increase in life limit is automatic for existing and future U.S.-registered aircraft as the company works to get the new limits accepted by other civil aviation authorities. Structural inspections as specified in the AMM are still required.

The FAA-approved changes to the aircraft life limits greatly simplifies the ability of Eclipse jet owners and operators to benefit from the extensive investment made by One Aviation in structural life testing, said Brent Christner, the companys senior director of engineering.

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FAA Issues Structural Life Extension for Eclipse Jets | Business ... - Aviation International News

BWXT Nuclear Energy Canada Awarded CA$34 Million Contract for Primary Heat Transport Motors – Business Wire (press release)

PETERBOROUGH, Ontario--(BUSINESS WIRE)--BWX Technologies, Inc. (NYSE: BWXT) announced today that its subsidiary BWXT Nuclear Energy Canada Inc. (BWXT NEC) has been awarded a CA$34 million, five year contract to supply seven primary heat transport motors for Bruce Power. The motors are part of Bruce Powers life-extension program that will extend the life of six of its reactors to continue providing Ontario with clean, low-cost and reliable electricity for decades to come.

The primary heat transport motors are required to drive the main circulating pumps used to push heavy water through the reactor core into the steam generators. The scope of the contract includes the project management, engineering and manufacturing of seven 11,000 horsepower motors. Work under this contract will commence immediately with the first motor scheduled to be delivered to Bruce Power in mid-2018.

We appreciate the opportunity to execute this important project for Bruce Power and take great pride in our contributions to its life extension program, said John MacQuarrie, president of BWXT Canada Ltd. and BWXT NEC. BWXT is pleased to be in a position to supply its customers with a multitude of product and service solutions to assist them in extending the lives of their nuclear plants.

Partnering with BWXT for this important motor work is critical to ensuring the life extension and operation through 2064, said Mike Rencheck, Bruce Powers president and CEO. Planning and preparation is key to our continued on-time and on-budget performance since January 2016 when our life extension program was started. Suppliers like BWXT and their performance are critical to our success; its a team effort.

Nuclear energy plays a significant role to Ontarios economy and it is great to see the positive effects of Bruce Powers life extension project being felt right here in Peterborough, said Jeff Leal, Member of Provincial Parliament. Throughout its program to extend the life of six of its reactors, Bruce Power will inject billions into Ontarios economy and generate thousands of jobs.

Bruce Power supplies 30% of Ontarios electricity at 30% less than the average cost to generate residential power. Extending the operational life of the Bruce Power units to 2064 will create and sustain 22,000 direct and indirect jobs every year, create $4 billion in annual Ontario economic benefit, and will ensure low-cost, clean and reliable energy for Ontario families and businesses.

Forward Looking Statements

BWXT cautions that this release contains forward-looking statements, including statements relating to the performance, timing and value, to the extent contract value can be viewed as an indicator of future revenues, of the Bruce Power contract. These forward-looking statements involve a number of risks and uncertainties, including, among other things, modification or termination of the contract and delays. If one or more of these or other risks materialize, actual results may vary materially from those expressed. For a more complete discussion of these and other risk factors, please see BWXTs annual report on Form 10-K for the year ended December 31, 2016 and subsequent quarterly reports on Form 10-Q filed with the Securities and Exchange Commission. BWXT cautions not to place undue reliance on these forward-looking statements, which speak only as of the date of this release, and undertakes no obligation to update or revise any forward-looking statement, except to the extent required by applicable law.

About BWXT Nuclear Energy Canada Inc.

BWXT Nuclear Energy Canada Inc. (BWXT NEC), a subsidiary of BWXT Canada Ltd., has more than 60 years of extensive experience and innovation in the supply of nuclear fuel and fuel channel components, services, equipment and parts for the CANDU nuclear power industry. This includes designing and supplying highly reliable nuclear equipment to fuel, inspect and refurbish reactors. BWXT NEC employs approximately 350 skilled employees at three locations in Ontario: Peterborough, Toronto and Arnprior. Learn more at http://www.nec.bwxt.com.

About Bruce Power

Formed in 2001, Bruce Power is an electricity company based in Bruce County, Ontario. We are powered by our people. Our 4,200 employees are the foundation of our accomplishments and are proud of the role they play in safely delivering clean, reliable, low-cost nuclear power to families and businesses across the province. Bruce Power has worked hard to build strong roots in Ontario and is committed to protecting the environment and supporting the communities in which we live. Learn more at http://www.brucepower.com and follow us on Facebook, Twitter, LinkedIn, Instagram and YouTube.

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BWXT Nuclear Energy Canada Awarded CA$34 Million Contract for Primary Heat Transport Motors - Business Wire (press release)

New ICBM Cheaper Than Upgraded Minuteman: Boeing On GBSD – Breaking Defense

Airmen install a new cable run on an aging Minuteman III missile.

ARLINGTON: A brand-new ICBM may cost the nation more than $85 billion, but keeping the geriatric Minuteman will cost even more. Thats according to Boeing, the aerospace giant that began building the original Minuteman I in 1958 and has maintained the much-modified Minuteman III since 1970.

Minuteman III in silo

Sure, the company can reset the odometer on the Minuteman with yet another service life extension program (SLEP), Boeing strategic deterrence chief Frank McCall told reporters this morning. But its still a 1950s design upgraded over six decades with a mix of technologies it was never intended to accommodate. While parts of the guidance and propulsion systems date to 1993, for example, some parts are so old the original manufacturers have long since gone out of business. That forces the Air Force to expensively reinvent the wheel or, say, a 1961-vintage mechanical coding device.

So for about the same price as a rebuilt Minuteman, McCall told us, Boeing would rather build you an all-new missile. Thats what the Air Force calls the Ground-Based Strategic Deterrent. (Lockheed and Northrop are also competing). GBSD would get you better performance, he said, including against modern, precision-guided missile defenses, which didnt exist when the Minuteman was designed. (Back then, cutting-edge missile defense destroyed incoming warheads by detonating a nuclear weapon over your own territory). It would be flexible for a wide range of scenarios, whereas the Minuteman was optimized for a massive exchange with Russia across the North Pole. And even sticking with low-risk, proven technology, it would be decades more advanced than Minuteman.

The new missile would also feature a modular, plug-and-plug design known as open architecture that would make replacing components both for maintenance and upgrades much easier than on the Minuteman III. Most important, perhaps, the new missile would be designed from the start to last for decades until at least the 2070s while Minuteman was originally meant to last just 10 years. Between the open architecture and the build-to-last philosophy, McCall said, GBSD would be cheaper to maintain over the long haul than Minuteman.

Back in June, Gen. John Hyten, head of Strategic Command, lamented the time and money it would take to develop GBSD: $85 billion over 20 years for 400 missiles, compared to $17 billion in todays dollars over five years for the initial 800 Minutemans. The military-industrial complex needs to relearn how to go fast, take risks, fail, and try again, he said, instead of grinding along in todays bureaucratic, cripplingly slow acquisition system.

But as expensive as GBSD was, Hyten emphasized, it was still cheaper than re-re-rebuilding the Minuteman: You will have ended up replacing just about everything on the missile, which will cost you more (than GBSD), but nobody believes me. Now that weve heard more of the details from Boeing, maybe we will.

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New ICBM Cheaper Than Upgraded Minuteman: Boeing On GBSD - Breaking Defense

BAE Systems sales fire up as tank orders roll in – shropshirestar.com

The defence giant saw sales increase by four per cent to 9.6 billion in the first six months of the year, while underlying profits were 11 per cent to 945 million compared to the same period a year ago.

In its UK Platforms And Services division, which includes the armoured vehicles maintenance division at Hadley Park in Telford where it employs about 200 people, saw sales rise by seven per cent to 3.9 billion as orders continued to flood in.

"The business has continued to provide support to previously supplied armoured vehicles and bridging systems, with orders of 14 million received in the period," the company said.

"The business is one of two contenders delivering the first stage of the Challenger 2 Life Extension Project."

Telford is home to the Challenger 2 project team, which is currently assessing what needs to be done to allow the British Army's main battle tank to remain in service until 2035.

BAE added that while the General Election had led to the formation of a minority government, "defence and security is expected to remain a priority".

The company added that it was still looking for ways to cut costs.

Chief executive Charles Woodburn said: "Strong programme execution, technology and enhanced competitive positions will be key in driving the business forward, and we will continue to focus on efficiency and meeting our customers' affordability challenges.

"With the expected improvement in the defence budget outlook in a number of our markets, the group is well placed to continue to generate good returns for shareholders."

The group also said it would take a charge in the second half for overhauling its cyber and intelligence arm, where revenues are "softening".

The weak pound against a strong dollar has helped BAE as it makes sales in the United States more valuable when translated into sterling earnings.

Shares in the group rose three per cent after the results.

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BAE Systems sales fire up as tank orders roll in - shropshirestar.com

US approves $115m sale of F/A-18 Super Hornet upgrades to Switzerland – Airforce Technology

The US Defense Security Cooperation Agency (DSCA) has notified Congress of a potential $115m foreign military sale of F/A-18 Super Hornet upgrades to Switzerland.

Under the sale, Switzerland seeks to receive a Service Life Extension Program for its F/A-18C/D aircraft.

The deal covers up to 50 multifunctional information distribution system joint tactical radio system (MIDS JTRS) with Concurrent Multi-Net 4 (CMN-4) capability, and 50 ARC-210 GEN 5 RT-1900A(C) radios with second-generation anti-jam tactical UHF radio for Nato (SATURN) frequency hopping. It also includes 20 Joint Helmet-Mounted Cueing Systems (JHMCS) with Night Vision Cueing Displays (NVCD), and CIT automated dependence surveillance-broadcast (ADS-B) out.

The Government of Switzerland also requested software enhancements to the APG-73 radar, improvements to the F/A-18 Software Configuration Set (SCS) 29C, and sustainment for the ALQ-165 Airborne Self Protection Jammer (ASPJ) system.

The operational support for these modifications will be provided through upgrades to the purchasers unique Mission Data System, DSCA stated.

"The procurement will help the Swiss Air Force to extend the useful life of its F/A-18 fighter aircraft, and enhance the survivability."

The sale also includes system integration and testing, software development and integration, support equipment, spare and repair parts, as well as maintenance personnel and pilot familiarisation training. It also covers software support, publications and technical documents, and US Government and contractor technical assistance.

The procurement will help the Swiss Air Force to extend the useful life of its F/A-18 fighter aircraft, and enhance the survivability.

Boeing, McDonnell Douglas, Data Link Solutions, Rockwell Collins and Rockwell Collins ESA Vision System will serve as principal contractors for the sale, which is expected to increase Switzerlands tactical aviation operational capabilities.

Built by Boeing, F/A-18 Super Hornet is a twin-engine, supersonic, all weather multirole fighter jet that is capable of landing and taking off from an aircraft carrier.

Boeing has said it offers a suite of upgrades for the F/A-18 Super Hornet, including conformal fuel tanks, an enclosed weapons pod, an enhanced engine, and a reduced radar signature.

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US approves $115m sale of F/A-18 Super Hornet upgrades to Switzerland - Airforce Technology

TransCanada still sees producer support for Keystone XL – WorldOil (subscription)

By Kevin Orland on 7/31/2017

CALGARY (Bloomberg) -- TransCanada Corp. said it still expects commercial support for its controversial Keystone XL oil pipeline, tamping down speculation that it was having trouble finding customers for thelong-delayed line.

Keystone XL, which was rejected by the Obama administration before being revived by President Donald Trump this year,would boost TransCanadas dividend growth, the company said in a statement Friday. Media reports in recent weeks said that the company was having trouble signing up customers for the pipeline, conceived to help move crude from Albertas oil sands to refineries on the U.S. Gulf Coast.

TransCanada said earlier this year that it was working to sign new shippers following years of delays. Given the time it took to gain federal approval, TransCanada said it expected some shippers to reduce their volume commitments and that other new customers would be introduced. The company said on Thursday that its soliciting additional commitments to ship oil on Keystone XL.

Weve had good support from our legacy shippers, which gives us a good base to launch this open season, Paul Miller, TransCanadas president of liquids pipelines, said on a conference call.

The open season closes on Sept. 28, with the results of the process expected to be finalized in late November, Miller said. The company should also receive its regulatory decisions from Nebraska around that time and will weigh both of those factors in determining whether to proceed with the line, he said. If TransCanada decides to move ahead on Keystone XL, it would need six to nine months to prepare for construction and about two years to build it, he said.

The shares were up 0.2% at C$63.66 as of 1:44 p.m. in Toronto. Calgary-based TransCanada gained 5% this year through Thursday.

Dividend growth

Success in advancing Keystone XL or other growth initiatives such as the Bruce Power life extension may augment or extend the companys dividend growth outlook, CEO Russ Girling said in the statement. The company plans to increase its annual dividend at the upper end of an 8% to 10% range through 2020.

Keystone won votes of confidence from the chief executive officers of Canadian oil producers Cenovus Energy Inc. and Suncor Energy Inc. this week. The CEOs both said they support Keystone and that the Canadian energy industry needs more pipeline capacity. Suncor confirmed that it plans to ship its products on Keystone.

Albertas oil producers have long warned that a lack of pipeline space was hurting their prospects. That pipeline pinch may start to hit the industry later this year as Suncors massive Fort Hills oil-sands project starts to produce oil and Canadian Natural Resources Ltd. completes another phase of expansion at its Horizon mine.

Beyond Keystone

Looking beyond Keystone, TransCanada is spending C$2 billion ($1.6 billion) to expand its natural gas pipeline network in Western Canada. The upgrades to the Nova Gas system will include 171 mi (275 km) of new pipeline, additional compression and new metering stations.

The company said on Friday that it was applying to the National Energy Board to expand capacity on its Canadian Mainline, which carries natural gas from producers in Alberta to markets in the nations east. The company would spend about C$160 million on the project, which is underpinned by 15-year contracts.

TransCanadas second-quarter profit was 76 Canadian cents a share, excluding some items. Theaverage estimate of analysts surveyed by Bloomberg was 68 cents.

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TransCanada still sees producer support for Keystone XL - WorldOil (subscription)

Silicon Valley looking to extend life | News, Sports, Jobs – The … – Tiffin Advertiser Tribune

So it was that Eos, goddess of the dawn, fell in love with Tithonus, a handsome young prince of Troy and, beguiling him with her beauty, brought him to her palace on Mount Olympus.

They lived happily for many years but, being mortal, age eventually overtook Tithonus. In her despair, Eos beseeched Zeus to grant her love immortality. Moved to pity, he granted her request but even the king of Olympus could not bestow eternal youth on a human for that would make him as one of the gods.

As one age passed into the next, Tithonus, withered and shrunken, cried incessantly for release from his torment but Zeus could not undo a wish once granted. It was Eos who eventually provided her poor lover a measure of relief by transforming him into a cicada. Now each summer he emerges from the ground with a fresh body to sing in eternal praise of his beauteous goddess. Or is it rather a lament over his crusted, hollow shell of a body?

Many of the myths and stories we have long told ourselves are cautionary tales against the dangers of hubris, our overconfident pride and arrogance before the gods. Divinity will mete out retribution to those who forget their place in the natural scheme of things. Chief among these absolutes of the human condition is our mortality; we all must die and woe betide any who would seek to have it otherwise.

But consider this statement from the website of the California Life Co. (Calico), a biotechnology firm established in 2013:

Calico is a research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan. We will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Executing on this mission will require an unprecedented level of interdisciplinary effort and a long-term focus for which funding is already in place.

The company is a subsidiary of Alphabet Inc., whose most famous other subsidiary goes by the name of Google. By 2016, Larry Page, Alphabets CEO (and co-founder of Google) had committed the company to contributing $240 million to Calico, with an additional $490 million should it be needed.

Calico is by no means the only Silicon Valley outfit investing big dollars in the life extension sciences field. SENS (Strategies for Engineered Negligible Senescence) Research Foundation, founded in 2009, and Human Longevity Inc., founded in 2014, are two of its better-funded competitors but there are others.

Whats going on here? Lets start with some data. Since 1900, the average human life span has increased by 30 years. But with this, so have the rates of age-related health issues such as cancer, heart disease, stroke, diabetes and dementia. In the U.S., up to age 44 the leading causes of death are accidents and violence. From there to age 65, its cancer and heart disease after that.

Medical advances are making significant inroads on each of these diseases and they may be conquered within your childrens lifetime. What then? Well, epidemiologists suggest a cure for cancer would only add 3.3 years to the average lifespan while the prevention of heart disease would tack on another four years. The elimination of all disease likely would only extend life into the mid-90s.

To go further, the aging process itself must be slowed. Even in the absence of disease, our bodies senesce as our organs, tissues, cells and macromolecules accumulate damage at an ever-increasing rate. Eric Verdin of the Buck Institute for Research on Aging has observed that if you just kept aging at the rate you age between 20-30, youd live to a thousand. But at 30, everything starts to change. Thereafter your risk of mortality doubles every seven years.

Most longevity scientists are health spanners, seeking a healthier life with a compressed morbidity (i.e., a quick and painless death). But immortalists like SENS Research founder Aubrey de Grey and futurist Ray Kurzwell believe science can carry us much further. If aging is encoded in the DNA of our genes, they argue, there should be no technological reason why we couldnt identify and address those parts of our genomes that are responsible for senescence.

Like so much else in modern biology, medical research is increasingly becoming an information science. To find the genetic correlates of aging will entail the compilation and analysis of an almost unthinkable mass of biotechnical data. Who has the big-data skillset and financial resources to back such an undertaking?

Silicon Valley.

But what about the economics, ethics and religious implications of an immortality united with youthful vigor? Should aging be viewed as a medical disease to be treated as any other or are we just asking for it with such hubristic thinking?

Ken Baker is a scientist and a retired biology professor. If you have a natural history topic youd like the author to consider for an upcoming column, email your idea to rweaver@advertiser-tribune.com.

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A surgeon aiming to do the first human head transplant says ‘Frankenstein’ predicted a crucial part of the surgery – South China Morning Post

By Erin Brodwin

To Sergio Canavero, Frankenstein is scientific inspiration.

The Italian neurosurgeon told Business Insider that Mary Shelleys classic novel convinced him that he could complete the worlds first full-body transplant. Canavero claims hell complete the procedure on a human next fall in China.

Not only did the book reveal a missing piece in his plan to swap the heads of two humans, Canavero said, it also provided the justification for the dangerous procedure.

Just as the fictional Doctor Victor Frankenstein discovered how to give life to inanimate matter, Canavero aims to cheat death. The surgeon envisions a future in which healthy people could opt for full-body transplants as a way to live longer, eventually even putting their heads on clone bodies.

Im into life extension, he told Business Insider on a recent Skype call. Life extension and breaching the wall between life and death.

In fact, Canavero said that in doing the procedure he wants to create a near death experience actually a full death experience and see what comes next.

As Canavero explained it, the full-body transplant will involve going into the spinal cord of someone with a spinal injury and cutting out the injured segments of the cord. The donors cord would be cut to perfectly replace the missing portion in the injured person, and then the two healthy stumps would be fused together. Canavero plans to attach the cords using polyethylene glycol (PEG), a common laboratory tool used to encourage cells to fuse. Canavero simply refers to it as glue.

He said he will soon complete this transplant procedure with two humans a Chinese national who remains anonymous and a brain-dead organ donor. The head of the former will be attached to the body of the latter.

The full procedure is called HEAVEN, short for head anastomosis venture.

Canavero said that hed been studying the concept of this full-body transplant for more than a decade before he picked up Shelleys book. After reading it, he said he realised his planned procedure lacked a critical component: electricity.

The surgeon has not elaborated on the role electricity will play in the operation, however James FitzGerald, a consulting neurosurgeon at the University of Oxford, told Business Insider that PEG is can be paired with large pulses of electricity to coax fibers into merging. Still, FitzGerald maintains that Canaveros plans to use it to fuse two spinal cords are unrealistic.

Its just too much of a jump, FitzGerald said.

Canavero doesnt think so.

Electricity has the power to speed up regrowth, he said. Bing bang bong you have the solution to spinal cord fusion.

Canavero isnt pursuing this unprecedented medical feat to cure people with life-threatening injuries, despite the fact that spinal cord injuries affect 12,000 Americans every year. Instead, he wants the operation to serve as a way to explore his own ideas about life, death, and human consciousness (though he says it would be a waste not to help injured patients as well).

Im not religious but I dont believe consciousness can be created in the brain. The brain is a filter, he said, adding that the word anastomosis combines the Greek roots ana, meaning to place upon, and stoma, or mouth.

Like a kiss, he said.

Canaveros evidence that the procedure will work rests on a handful of animal experiments that many experts say were nowhere near satisfactory.

In the first of these experiments, Canavero claimed to have severed then reconnected the spinal cord of a dog. Less than a year later, he published a paper detailing how he created a series of two-headed rodents. In June 2017, the surgeon said he severed the spinal cords of a group of mice and then reattached them using polyethylene glycol.

Canavero says these trials are proof that he and his team figured out whats often considered the holy grail of spinal cord research: fusion.

We have so much data that confirms this in mice, rats, and soon you will see the dogs, he said.

However, many experts dont buy his claims, citing a lack of evidence. And its important to keep in mind that the fate of the Chinese man who will be involved in the first procedure hangs in the balance.

I simply dont think the reports of joining spinal cords together are credible, James FitzGerald, a consulting neurosurgeon at the University of Oxford, told Business Insider.

Robert Brownstone, a professor of neurosurgery and the Brain Research Trust Chair of Neurosurgery at the University College London, agreed.

Many great scientific ideas are born out of crazy ideas that turned out to be right so we cant completely turn a blind eye to this, but there has to be some mechanistic aspect to it, which Im not seeing, Brownstone said.

Others, including University of Cambridge neurosurgery professor John Pickard, suggested the journal in which Canaveros studies were published was also a red flag.

I just dont think hes done the science, Pickard said.

http://www.businessinsider.com/head-transplant-surgeon-frankenstein-2017-7

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A surgeon aiming to do the first human head transplant says 'Frankenstein' predicted a crucial part of the surgery - South China Morning Post

This Study Could Help Extend the Human Lifespan – Futurism

In BriefResearchers have identified a single gene deletion in E. colibacteria that influence longevity in C. elegans worms. This pointsto the role of gut bacteria in life extension and points to thepossibility of a life-extending probiotic in the future.

Researchers at the Baylor College of Medicine have found the key to longevity in Caenorhabditis elegans (C. elegans) worms and maybe, someday, humans. The team noticed that genetically identical worms would occasionally live for much longer, and looked to their gut bacteria to find the answer. They discovered that a strain of E. coli with a single gene deletion might be the reason that its hosts lives were being significantly extended.

This study is one among a number of projects that focus on the influence of the microbiome the community of microbes which share the body of the host organism on longevity. Ultimately, the goal of this kind of research is to develop probiotics that could extend human life. Ive always studied the molecular genetics of aging, Meng Wang, one of the researchers who conducted the study, told The Atlantic. But before, we always looked at the host. This is my first attempt to understand the bacterias side.

Even in cases like this, where it seems fairly obvious that the microbiome is influencing longevity, parsing out the details of how and why this happens among a tremendous variety of chemicals and microbe species is extremely complex. The team, in this case, was successful because they simplified the question and focused on a single relationship.

Genetically engineering bacteria to support and improve human health and even to slow aging and turning it into a usable, life-extending probiotic wont be easy. It is extremely difficult to make bacteria colonize the gut in a stable manner, which is a primary challenge in this field. The team, in this case, is looking to the microbiome, because the organisms used would be relatively safe to use because they would originate in the gut.

Clearly, researchers dont know yet whether these discoveries will be able to be applied to people, though it seems promising. Despite the obvious differences between the tiny C. elegans worm and us, its biology is surprisingly similar; many treatments that work well in mice and primates also work in the worm. The team will begin experiments along these same lines with mice soon.

Other interesting and recent research hoping to stop or slow the march of time includes work with induced pluripotent stem (iPS) cells, antioxidants that target the mitochondria, and even somewhat strangework with cord blood. It seems very likely that we wont have a single solution offering immortality anytime soon, but instead a range of treatment options that help to incrementally hold back time. And, with an improving quality of life, this kind of life extension sounds promising.

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This Study Could Help Extend the Human Lifespan - Futurism

Does doxycycline treat h pylori ulcers – Shelf life extension program doxycycline – Longboat Key News

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GARDENING: Reviving St. Augustine grass – Odessa American

Floyd is a horticulturist with Texas AgriLife Extension Service. He can be reached at 498-4071 in Ector County or 686-4700 in Midland County or by email at Jeff.Floyd@ag.tamu.edu

Floyd is an Agri-Life Extension agent for Ector and Midland counties. To learn more, call the Ector County Extension office at 432-498-4072, or the Midland County Extension office at 432-686-4700, or email jeff.floyd@ag.tamu.edu.

Posted: Sunday, July 2, 2017 3:00 am

GARDENING: Reviving St. Augustine grass By Jeff Floyd Odessa American

Weve discussed a lot of the problems that St. Augustine grass experiences in West Texas lawns but a recent question caused me to realize we havent talked about a basic St. Augustine maintenance schedule for our area.

Question: We have had great success growing Bermuda and St. Augustine, we have mostly shade, and the St. Augustine took over most of the yard. Last year we noticed the St. Augustine was not growing and yellowing and disappearing. It continues to get worse this year. This season I have fertilized, insect and bug killer granules, and Fungicide. No change. Last year I tried Ironite with no change. This month I laid down a strip of dolomite lime, and on the other side of yard a strip of aluminum sulfate. No detectable difference on either side.

Answer: Thank you for the question to Extension. Avoid applying any more amendments or fertilizers until youve gotten on track with a basic maintenance plan and start to see some recovery.

For St. Augustine lawns showing signs of stress, begin with a soil test. Visit http://www.soiltesting.tamu.edu for forms and instructions.

Call the Texas A&M AgriLife Extension office if you are having turf grass problems at 498-4071.

Posted in Gardening on Sunday, July 2, 2017 3:00 am. | Tags: Texas A&m Agrilife Extension Office, Jeff Floyd, Pecans, Pruning, Prune, Soft Landscape Materials, Landscape, Gardening, Gardener, Food, Integra, Repeat Applications, West Texas

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GARDENING: Reviving St. Augustine grass - Odessa American

SES and MDA Announce First Satellite Life Extension Agreement – Space Daily

SES and MDA, a global communications and information company, has announced an agreement for an initial satellite life extension mission using an on-orbit refuelling vehicle being built by SSL, a US based subsidiary of MDA and a leading provider of innovative satellites and spacecraft systems.

SES will be the first commercial customer to benefit from the satellite refuelling service, and will be able to activate the service whenever required with minimal disruption to spacecraft operation. The agreement also includes an option for further life extension missions.

SES will work with a new venture, Space Infrastructure Services (SIS), which will commercialise sophisticated satellite servicing capabilities. SIS has contracted SSL to design and build the highly-capable satellite servicing spacecraft vehicle to meet the needs of the US Defense Advanced Research Projects Agency (DARPA)'s Robotic Servicing of Geosynchronous Satellites (RSGS) programme, which is designed to inspect, repair, relocate and augment geosynchronous satellites and plans to include a refuelling payload to extend the life of satellites that are low on propellant.

"Satellite in-orbit servicing is of upmost importance to next-generation architectures for communications satellites. It enables satellite operators like us to have more flexibility in managing our fleet and meeting our customers' demands," said Martin Halliwell, Chief Technology Officer at SES.

"After witnessing the due diligence of SSL's and MDA's technical expertise, we are confident that its new venture is the best partner in the refuelling mission field, and will be able to help SES get more value out of an on-orbit satellite."

"As a pioneer in next-generation fleet capabilities, SES is clearly committed to improving the space and satellite ecosystem," said Howard L. Lance, President and CEO at MDA. "We are very pleased to have this refuelling contract with SES and are excited to provide them with more options in fleet management."

The satellite servicing spacecraft vehicle is planned for launch in 2021.

With the rise of Ad Blockers, and Facebook - our traditional revenue sources via quality network advertising continues to decline. And unlike so many other news sites, we don't have a paywall - with those annoying usernames and passwords.

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SES and MDA Announce First Satellite Life Extension Agreement - Space Daily

Possible mine-life extension good news for contractors – Otago Daily Times

Contractors and suppliers to Oceana Gold in Macraes, East Otago have been buoyed by news the mine could have its life extended to a decade.

Like Rio Tintos aluminium smelter at Tiwai Point, near Bluff, the company employs hundreds of staff but the flow-on effect of contract work accounts for many more pay packets overall.

Oceanas chief executive earlier this week raised the possibility of Macraes mine life being pushed out from beyond 2020 to 10 years, on the back of positive exploration results during the past quarter.

Oceana general manager at Macraes Dale Oram was contacted and confirmed exploration at Macraes was accruing at a rate that in two years could mean a formal five-year mine life.

Oceana has more than 500 employees at Macraes, using a further 60 contractors on site and for shut-down maintenance, and can employ a further up to 150 casual staff.

Skevington Contracting managing director Blair Skevington said the potential for a 10-year mine life was "pretty huge for us", being one of the larger contractors to Oceana.

"Yes, there should be some potential for [company] growth for us," he said.

Skevington is a preferred contractor at Macraes and has been there 14 years, employing up to 13 staff operating the smaller earthmoving equipment such as diggers, bulldozers and lighter trucks.

Amalgamated Workers Union secretary Calvin Fisher said "any life-of-mine extension had to be welcomed".

"There would be a significant economic down side to Dunedin, and wider Otago, if Macraes closed. They have one of the biggest payrolls in the area."

Because of the high pressure on cost controls, it was always "unsettling" for staff when they faced restructuring, such as changes to hours, rostering or salaries.

"We have differences of opinion ... but wed like to think we can do it collaboratively," Mr Fisher said.

Waikouaiti Auto & Engineers Dunedin workshop branch manager Barin Black said the potential extension was "great news for us and the community".

"People dont realise just how many jobs, directly and indirectly, there are," he said.

Between Dunedin and Waikouaiti the company had almost 40 staff, doing most of the engineering work on the Macraes ore-processing equipment.

Mr Black said the length of mine life was "all important", as Oceana was more likely to upgrade equipment sooner if the formal mine life was five years and not three years.

Waikouaiti Auto & Engineers also supplied casual staff for maintenance shutdowns when processing equipment was refurbished.

Mr Oram highlighted Macraes had to "compete" with Oceanas other sites for exploration cash each calendar year.

Exploration spending this year at Macraes is likely to come in at the budgeted $US8 million ($NZ10.9 million).

He was "hopeful" Macraes would attract similar, up to $US8 million, amounts for exploration for both 2018 and 2019.

He said not all areas had been explored as planned this year, but more drilling was proposed at the Round Hill site, where studies had been undertaken into dual tungsten and gold mining.

However, the price of tungsten had since fallen and there were processing issues that were still being studied, he said.

"More than likely it will be a gold site, but its make or break if it goes ahead."

He had appointed a community and environment manager this year, given the interaction with local stakeholders, such as farmers, who saw the greatest impact from mining activities, he said.

"Some locals mentioned the other day they were expecting us to be here for five or seven years, but here we are 27 years on," he said.

simon.hartley@odt.co.nz

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How does where you live affect your life expectancy? | PBS NewsHour – PBS NewsHour

Courtesy Institute for Health Metrics and Evaluation at the University of Washington

The fruits of so-called free enterprise have long been debated in economics. The goal has been wealth or human welfare at least since Adam Smith published An Inquiry into the Nature and Causes of the Wealth of Nations in 1776. But what exactly is human welfare? And how do we measure wealth?

The obvious way: money. Simply measure how much money a society or individual earns or possesses, because money is so damn simple to count. But various economists have rejected simple as simplistic. Do we not care about values other than money? Education, say? Freedom? Health?

Nobel laureate economist Amartya Sen, for example, has long proposed we instead use a human development index that includes variables beyond monetary wealth.

And in using money as your key metric, you miss the side effects of becoming a latter day Uncle Scrooge, swimming in coin.

Consider the potentially corrosive effects of money on a fellow like Scrooge theres experimental evidence that rich people are more likely to break the law while driving, help themselves to candy meant for children, cheat in a game of chance or lie, as demonstrated in a Making Sen$e story we did a few years ago. Or more broadly and starkly, imagine that a town becomes rich by building a chemical plant, but pollution from the plant poisons its citizens for decades to come.

The most dramatic finding is that U.S. counties vary in life expectancy by as much as 20 years.

There is, however, one measure that seems relatively unobjectionable: life expectancy at birth. Leaving aside the thorny issue of life extension for its own sake, what is more desirable than more life?

Which brings us to the extraordinary new interactive map from the University of Washingtons Institute for Health Metrics and Evaluation a county by county report on life expectancy in the United States as it has developed from 1980 to 2014.

The most dramatic finding is that U.S. counties vary in life expectancy by as much as 20 years. At the bottom: Oglala Lakota County, in South Dakota. The area, which includes the Pine Ridge Native American reservation, has a 2014 life expectancy of 66.8 years lower than the average of 67.2 in Sudan.

At the top, a group of ski valley counties in central Colorado like Summit, where the life expectancy is 86.8 years two years higher than any country on earth. (Aspen residents need not feel jealous; their Pitkin County has an average life expectancy of 86.5 years.)

We asked the chief researcher behind the project, Ali Mokdad, what most surprised him.

in many places in this country, life expectancy is stagnant, only slightly improving, and its not keeping up with other Western countries were competitive with.

First, he said: the disparity is increasing between the lowest and the highest. And second: in many places in this country, life expectancy is stagnant, only slightly improving, and its not keeping up with other Western countries were competitive with.

As to why Oglala Lakota County in South Dakota is at the very bottom of the life expectancy, Mokdad has a predictable answer.

Socioeconomic factors: education and income. An educated woman is more likely to seek health care or have access to health care and insurance,

In the U.S., life expectancies can very by as much as 20 years depending on county. Photo by Sally Anscombe/via Getty Images

For the Colorado counties where life expectancy is higher than any country in the world, its the reverse. They tend to be affluent, have health insurance, access to good health centers. If you click on the obesity visualization, youll see that obesity is very low.

So what, in the end, are the key factors influencing life expectancy?

The opioid pandemic is certainly one of them, Mokdad says, but 74 percent of the difference between counties hinges on four lifestyle choices that are, in his words, preventable: blood pressure, obesity, smoking and physical inactivity.

Where does your county rank? Take a look at the interactive map to find out.

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How does where you live affect your life expectancy? | PBS NewsHour - PBS NewsHour

Life Extension and Insilico Medicine Use Artificial Intelligence to Develop Ageless – WholeFoods Magazine

Fort Lauderdale, FL Life Extension has partnered with Insilico Medicine to introduce Ageless Cell, the first supplement in its GEROPROTECT line to promote healthy aging by inhibiting cellular senescence.

Cellular senescence is a natural part of the aging process where cells no longer function optimally, affecting organ function, cellular metabolism, and the inflammation response. The accumulation of these senescent cells contributes to the process of aging. The Ageless Cell supplements inhibit the effects of cellular senescence by acting as geroprotectors, or interventions aimed to increase longevity and impede the onset of age-related diseases by targeting and inhibiting senescence-inducing pathways and inhibiting the development of senescent cells.

The partnership with Insilico Medicine allowed researchers to use deep learning algorithms to comb through hundreds of studies and thousands of data points a process that could have taken decades to identify four key anti-aging nutrients: N-Acetyl-L-Cysteine (NAC), myricetin, gamma-tocotrienol, and EGCG. These compounds target pathways that are known to contribute to or protect against the development of senescent cells.

Specifically, NAC upregulates signaling pathways that protect cells against oxidative stress, which promotes cellular senescence. It also reduces pathways that promote inflammation. Myricetin regulates a family of stress-responsive signaling molecules known to regulate aging in many tissues. It also promotes cell differentiation and self-repair. Gamma tocotrienol modulates the mevalonate pathway that controls cholesterol production, cancer promotion, and bone formation. And EGCG regulates the Wnt pathway that determines the fate of developing cells and also prevents sugar-induced damage to tissues, helping to suppress their pro-aging effects.

Clinical aging studies are extremely difficult, if not impossible, to perform at this time. Our collaboration with Insilico Medicine has allowed us to develop geroprotective formulations by using artificial intelligence to study very large data sets, said Andrew G. Swick, Ph.D., senior vice president of product development and scientific affairs for Life Extension.

Scientists found these four nutrients have various complementary and reinforcing properties to influence key anti-aging pathways and combat aging factors by modulating specific biological pathways. By rejuvenating near-senescent cells and encouraging the bodys healthy process for dealing with senescent cells, Ageless Cell turns back the clock at the cellular level, said Michael A. Smith, M.D., senior health scientist for Life Extension.

Alex Zhavoronkov, Ph.D., CEO of Insilico Medicine said, Together, these four natural compounds represent the beginning of the future anti-aging cocktails identified using artificial intelligence under expert human supervision.

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Life Extension and Insilico Medicine Use Artificial Intelligence to Develop Ageless - WholeFoods Magazine

Life Extension and Insilico Medicine Use Artificial Intelligence to Develop Ageless Cell – WholeFoods Magazine

Fort Lauderdale, FL Life Extension has partnered with Insilico Medicine to introduce Ageless Cell, the first supplement in its GEROPROTECT line to promote healthy aging by inhibiting cellular senescence.

Cellular senescence is a natural part of the aging process where cells no longer function optimally, affecting organ function, cellular metabolism, and the inflammation response. The accumulation of these senescent cells contributes to the process of aging. The Ageless Cell supplements inhibit the effects of cellular senescence by acting as geroprotectors, or interventions aimed to increase longevity and impede the onset of age-related diseases by targeting and inhibiting senescence-inducing pathways and inhibiting the development of senescent cells.

The partnership with Insilico Medicine allowed researchers to use deep learning algorithms to comb through hundreds of studies and thousands of data points a process that could have taken decades to identify four key anti-aging nutrients: N-Acetyl-L-Cysteine (NAC), myricetin, gamma-tocotrienol, and EGCG. These compounds target pathways that are known to contribute to or protect against the development of senescent cells.

Specifically, NAC upregulates signaling pathways that protect cells against oxidative stress, which promotes cellular senescence. It also reduces pathways that promote inflammation. Myricetin regulates a family of stress-responsive signaling molecules known to regulate aging in many tissues. It also promotes cell differentiation and self-repair. Gamma tocotrienol modulates the mevalonate pathway that controls cholesterol production, cancer promotion, and bone formation. And EGCG regulates the Wnt pathway that determines the fate of developing cells and also prevents sugar-induced damage to tissues, helping to suppress their pro-aging effects.

Clinical aging studies are extremely difficult, if not impossible, to perform at this time. Our collaboration with Insilico Medicine has allowed us to develop geroprotective formulations by using artificial intelligence to study very large data sets, said Andrew G. Swick, Ph.D., senior vice president of product development and scientific affairs for Life Extension.

Scientists found these four nutrients have various complementary and reinforcing properties to influence key anti-aging pathways and combat aging factors by modulating specific biological pathways. By rejuvenating near-senescent cells and encouraging the bodys healthy process for dealing with senescent cells, Ageless Cell turns back the clock at the cellular level, said Michael A. Smith, M.D., senior health scientist for Life Extension.

Alex Zhavoronkov, Ph.D., CEO of Insilico Medicine said, Together, these four natural compounds represent the beginning of the future anti-aging cocktails identified using artificial intelligence under expert human supervision.

See the article here:
Life Extension and Insilico Medicine Use Artificial Intelligence to Develop Ageless Cell - WholeFoods Magazine

Texas A&M Agri-Life Extension Invites Resident to Partake in – RGVProud

RIO GRANDE VALLEY, Texas - Texas A&M Agri-Llife Extension is inviting residents to take advantage of the different programs they offer.

For more than 100 years now, the Texas A&M extension has been working to educate south Texans on a variety of topics.

The agency's educational process is based on research focused on local issues and needs. Whether it's diabetes management or learning different ways to eat healthy on a budget, they say there is a program for everyone.

Andrea Valdez, Agri-Life Extension Agent said, "Our job is to educate the community to live happier and healthier lives. We've been in this county for 100 years. So, we are a mainstay and we welcome everyone to join out program. Most of them are free. Some of them do have a charge but that's very rare.

For more information about Texas A&Ms educational programs, contact them at 956-383-1735. You can also find them online at hidalgo.agrilife.org.

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Texas A&M Agri-Life Extension Invites Resident to Partake in - RGVProud

Editorial March 29 2017 – Illawarra Mercury

28 Mar 2017, 8 p.m.

Editorial for the March 29 edition of the Illawarra Mercury.

It seems as though much of the first part of 2017 for the NSW Government has been spentunpicking what former Premier Mike Baird attempted to introduce in 2016.

First it was the scrapping of council mergers in regional areas.

Now the Berejiklian government has progressed the reforms of the greyhound industry, which was initially going to be banned outright by former Premier Mike Baird.

The Baird backdown on the ban sparked a review by an expert panel which revealed a series of recommendations to reform the industry instead of the more dramatic option.

On Tuesday Racing Minister Paul Toole announced the NSW Government would accept all but one of the recommendations by the expert panel.

The reforms are expected to cost $41million which will be ultimately paid by the taxpayer purse.

The bulk of the money will be focussed on reforms which the NSW Government hopes will provide better animal welfare.

The other $11 million will go towards the establishment of an agency aimed at policing the industry over the next five years, after which the industry will be required to fund the body.

These reforms will impact on all our local greyhound tracks in the region, Bulli, Dapto and further south in Nowra.

While the industry is welcoming the news it will continue as an industry, the critics are questioning whether the funding and the measures provide enough support to the industry and in the end the result for the industry will be what Mr Baird initially intended.

Bulli Greyhound Club operations manager Darren Hull certainly shared that view with the Illawarra Mercury.

I think it is a good thing that people know where they stand because come the 1st of July, the industry was still going to be banned, Mr Hullsaid.

However, there is probably still a little bit of a cloud, not hanging over the industrys head, but at some point in timeit will have to restructure to remain financial viable.

I dont know if that decision is going to involve scaling back the tracks, cutting back race meetings. But at some stage someone will have to make a call.

In the end this may well prove a life extension than a lifeline, but that remains in the hand of the industry.

More:
Editorial March 29 2017 - Illawarra Mercury

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