Good Odds for Those Who Need Bone Marrow Donor, Study Finds

Posted: July 25, 2014 at 9:49 am

By Dennis Thompson HealthDay Reporter

WEDNESDAY, July 23, 2014 (HealthDay News) -- Most blood cancer patients in the United States who need a bone marrow transplant can find an acceptable match through the National Marrow Donor Program, a new study has determined.

Depending on a patient's race or ethnic background, the study found that 66 percent to 97 percent of patients will have a suitably matched and available live donor on the registry.

Even hard-to-match ethnic groups can find a suitable donation thanks to banked stem cells drawn from umbilical cord-blood donations, said senior author Martin Maiers, director of bioinformatics research at the National Marrow Donor Program.

All told, for patients who are candidates for either bone marrow or cord-blood transplants, the likelihood of having a suitable match is as high as 91 to 99 percent, the study found.

"For almost all patients, there is some sort of product available for them," Maiers said.

The findings, said to represent the first attempt to accurately determine the successful-match rate of the bone marrow registry, are published July 24 in the New England Journal of Medicine.

Patients suffering from blood-related cancers such as leukemia or lymphoma need a stem cell transplant to help them survive their cancer treatment. The transplant is done after chemotherapy and radiation is complete.

Donation from a relative is the best option, but only about 30 percent of patients have such a donor available, researchers said in background notes. The majority must rely on the National Marrow Donor Program to match them with a live bone marrow donor or banked stem cells gathered from donated umbilical cord blood.

The National Marrow Donor Program has on hand 11 million potential bone marrow donors and 193,000 banked cord-blood donations. The number of transplants facilitated by the program has quadrupled, with nearly 6,000 transplants in 2012 compared with 1,500 a decade earlier.

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Good Odds for Those Who Need Bone Marrow Donor, Study Finds

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