An injectable bone marrowlike scaffold enhances T cell …

Posted: February 12, 2019 at 2:49 pm

Goronzy, J. J. & Weyand, C. M. Successful and maladaptive T cell aging. Immunity 46, 364378 (2017).

Liston, A., Enders, A. & Siggs, O. M. Unravelling the association of partial T-cell immunodeficiency and immune dysregulation. Nat. Rev. Immunol. 8, 545558 (2008).

Blazar, B. R., Murphy, W. J. & Abedi, M. Advances in graft-versus-host disease biology and therapy. Nat. Rev. Immunol. 12, 443458 (2012).

Krenger, W., Blazar, B. R. & Hollnder, G. A. Thymic T-cell development in allogeneic stem cell transplantation. Blood 117, 67686776 (2011).

Zlotoff, D. A. et al. Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation. Blood 118, 19621970 (2011).

Chaudhry, M. S., Velardi, E., Dudakov, J. A. & Brink, M. R. Thymus: the next (re) generation. Immunol. Rev. 271, 5671 (2016).

Mohtashami, M., Shukla, S., Zandstra, P. & Ziga-Pflcker, J. C. in Synthetic Immunology 95120 (Watanabe, T. & Takahama, Y., eds, Springer, Tokyo, 2016).

Perales, M.-A. et al. Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation. Blood 120, 48824891 (2012).

Skrombolas, D. & Frelinger, J. G. Challenges and developing solutions for increasing the benefits of IL-2 treatment in tumor therapy. Exp. Rev. Clin. Immunol. 10, 207217 (2014).

Dudakov, J. A. et al. Interleukin-22 drives endogenous thymic regeneration in mice. Science 336, 9195 (2012).

Cobbold, M. et al. Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLApeptide tetramers. J. Exp. Med. 202, 379386 (2005).

Rooney, C. M. et al. Infusion of cytotoxic T cells for the prevention and treatment of EpsteinBarr virusinduced lymphoma in allogeneic transplant recipients. Blood 92, 15491555 (1998).

Zakrzewski, J. L. et al. Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors. Nat. Biotechnol. 26, 453 (2008).

Van Coppernolle, S. et al. Functionally mature CD4 and CD8 TCR cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells. J. Immunol. 183, 48594870 (2009).

Awong, G. et al. Human proT-cells generated in vitro facilitate hematopoietic stem cellderived T-lymphopoiesis in vivo and restore thymic architecture. Blood 122, 42104219 (2013).

Love, P. E. & Bhandoola, A. Signal integration and crosstalk during thymocyte migration and emigration. Nat. Rev. Immunol. 11, 469 (2011).

Radtke, F., MacDonald, H. R. & Tacchini-Cottier, F. Regulation of innate and adaptive immunity by Notch. Nat. Rev. Immunol. 13, 427 (2013).

Serwold, T., Ehrlich, L. I. R. & Weissman, I. L. Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis. Blood 113, 807815 (2009).

Vionnie, W. et al. Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow. J. Exp. Med. 212, 759774 (2015).

Smith, K. Y. et al. Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy. J. Infect. Dis. 181, 141147 (2000).

Wozney, J. M. et al. Novel regulators of bone formation: molecular clones and activities. Science 242, 15281534 (1988).

Koshy, S. T., Zhang, D. K., Grolman, J. M., Stafford, A. G. & Mooney, D. J. Injectable nanocomposite cryogels for versatile protein drug delivery. Acta Biomater. 65, 3643 (2018).

Brainard, D. M. et al. Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virusinfected humanized BLT mice. J. Virol. 83, 73057321 (2009).

Douek, D. C. et al. Assessment of thymic output in adults after haematopoietic stem cell transplantation and prediction of T-cell reconstitution. Lancet 355, 18751881 (2000).

Smadja, D. M. et al. Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis. Arterioscler. Thromb. Vasc. Biol. 28, 21372143 (2008).

Lafage-Proust, M.-H. et al. Assessment of bone vascularization and its role in bone remodeling. Bonekey Rep. 4, 662 (2015).

Kuznetsov, S. A. et al. The interplay of osteogenesis and hematopoiesis: expression of a constitutively active PTH/PTHrP receptor in osteogenic cells perturbs the establishment of hematopoiesis in bone and of skeletal stem cells in the bone marrow. J. Cell Biol. 167, 11131122 (2004).

Song, J. et al. An in vivo model to study and manipulate the hematopoietic stem cell niche. Blood 115, 25922600 (2010).

Wils, E.-J. et al. Flt3 ligand expands lymphoid progenitors prior to recovery of thymopoiesis and accelerates T cell reconstitution after bone marrow transplantation. J. Immunol. 178, 35513557 (2007).

Maillard, I. et al. Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation. Blood 107, 35113519 (2006).

Garber, K. Driving T-cell immunotherapy to solid tumors. Nat. Biotechnol. 36, 215219 (2018).

Jangalwe, S., Shultz, L. D., Mathew, A. & Brehm, M. A. Improved B cell development in humanized NOD-scid IL2R null mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3. Immun. Inflamm. Dis. 4, 427440 (2016).

Ripamonti, U. Bone induction by recombinant human osteogenic protein-1 (hOP-1, BMP-7) in the primate Papio ursinus with expression of mRNA of gene products of the TGF- superfamily. J. Cell. Mol. Med. 9, 911928 (2005).

Heliotis, M., Lavery, K., Ripamonti, U., Tsiridis, E. & Di Silvio, L. Transformation of a prefabricated hydroxyapatite/osteogenic protein-1 implant into a vascularised pedicled bone flap in the human chest. Int. J. Oral Maxillofac. Surg. 35, 265269 (2006).

Warnke, P. et al. Growth and transplantation of a custom vascularised bone graft in a man. Lancet 364, 766770 (2004).

ClinicalTrials.gov. Dendritic cell activating scaffold in melanoma. https://clinicaltrials.gov/ct2/show/NCT01753089

Carragee, E. J., Hurwitz, E. L. & Weiner, B. K. A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned. Spine J. 11, 471491 (2011).

Biffi, R. et al. Use of totally implantable central venous access ports for high-dose chemotherapy and peripheral blood stem cell transplantation: results of a monocentre series of 376 patients. Ann. Oncol. 15, 296300 (2004).

Li, M. O. & Rudensky, A. Y. T cell receptor signalling in the control of regulatory T cell differentiation and function. Nat. Rev. Immunol. 16, 220 (2016).

Hoffmann, P., Ermann, J., Edinger, M., Fathman, C. G. & Strober, S. Donor-type CD4+CD25+regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J.Exp. Med. 196, 389399 (2002).

Wan, Y. Y. & Flavell, R. A. YinYang functions of transforming growth factor- and T regulatory cells in immune regulation. Immunol. Rev. 220, 199213 (2007).

Bencherif, S. A. et al. Injectable cryogel-based whole-cell cancer vaccines. Nat. Commun. 6, 7556 (2015).

Palchaudhuri, R. et al. Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Nat. Biotechnol. 34, 738 (2016).

Bencherif, S. A. et al. Injectable preformed scaffolds with shape-memory properties. Proc. Natl Acad. Sci. USA 109, 1959019595 (2012).

Macdonald, M. L. et al. Tissue integration of growth factoreluting layer-by-layer polyelectrolyte multilayer coated implants. Biomaterials 32, 14461453 (2011).

Sprinzak, D. et al. Cis-interactions between Notch and Delta generate mutually exclusive signalling states. Nature 465, 86 (2010).

Nandagopal, N. et al. Dynamic ligand discrimination in the Notch signaling pathway. Cell 172, 869880 (2018).

Zakrzewski, J. L. et al. Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation. Nat. Med. 12, 1039 (2006).

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