Archive for April, 2022
TRT Side Effects: The Big One to Avoid – T NATION
Your elevated hematocrit/hemoglobin might well be directly related to your TRT. If so, there are ways to address that. However, your TRT might only be partly to blame as there are other conditions that can either contribute to high hematocrit/hemoglobin or even give false readings.
Depending on your situation, here are several ways to address high levels of hematocrit/hemoglobin:
This is the most obvious solution to elevated hematocrit, but it's probably also the least popular. Hardly any man wants to use less testosterone and give up any of the increased energy, sexuality, and muscularity that the hormone has gifted him. But truth be told, a lot of men are probably taking more than they need. The standard TRT clinic dosage is 200 mg. a week, which is, frankly, equivalent to a mild steroid cycle.
A study conducted by the Department of Urology at University of California found that subcutaneous (subQ) injections (under the skin rather than into the muscle) led to higher levels of free T, along with evidence of subQ being physiologically superior to IM shots in several other important ways.
Men who received subQ injections of testosterone exhibited the following:
The second result is the kicker. Since subQ injections led to a 41% reduction in hematocrit levels, you could theoretically use the same dosage you use for intramuscular injections. Of course, given that subQ injections led to a 14% increase in total T, you might just use a lesser dosage anyhow and further reduce hematocrit while retaining all the positive effects of your TRT.
Studies have shown that testosterone creams and gels raise hematocrit less than intramuscular testosterone injections.
This is the standard go-to treatment for high hematocrit. Every pint donated has been shown to decrease hematocrit by about 3 points. Unfortunately, you'd likely have to continue to periodically donate blood if you hadn't adopted any other hematocrit-lowering strategies.
That being said, there's some evidence that hematocrit levels stabilize after donating blood five times. Whether that's universally true is unlikely.
You can donate blood to places like the Red Cross or have your doctor perform what's known as a "therapeutic blood draw." Be careful not to donate too often, though. Giving a pint of blood more than every two and a half months or so may lead to long stints of fatigue.
High hematocrit readings sometimes occur because the patient was simply dehydrated, making it appear that the concentration of red blood cells was higher than it really was.
Of course, one simple way to determine whether your high hematocrit was caused by dehydration is to do a little simple math: hematocrit must always be three times the value of hemoglobin. If it's lower (Hct<3 x Hb), you're over-hydrated. If it's higher (Hct>3 x Hb), you're dehydrated. Either way, you're getting a false value because of your hydration status.
Red meats are high in heme iron (the type of iron found only in animal tissues), which is more efficiently absorbed than non-heme iron (the type found in whole grains, nuts, seeds, legumes, and leafy greens), and ingesting it can raise hemoglobin and, subsequently, hematocrit.
Sleep apnea is a medical condition where patients suffer from fragmented sleep. They literally stop breathing from 10 to 50 seconds multiple times throughout the night.
As a result of this interrupted breathing/sleep, patients experience poor oxygen saturation, which forces the body to produce more red blood cells and more hemoglobin.
Evidence suggests that curcumin binds to ferric acid in the digestive system, thus reducing hemoglobin levels. Be sure to use micellar curcumin which is 95 times more bioavailable than regular curcumin with piperine.
If you've got high hematocrit/hemoglobin AND have high blood pressure, ask your doctor to consider switching your high blood pressure medicine to Losartan. It's been used by physicians since the early 2000s to bring down hematocrit in kidney transplant patients and patients with chronic obstructive pulmonary disease (COPD).
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TRT Side Effects: The Big One to Avoid - T NATION
It’s cruel to deny trans children the chance to think again – The Telegraph
Imagine your 13-year-old daughter is depressed and withdrawn and then, one day, she tells you shes trans and will, henceforth, be known as Sean. You must no longer call her by her dead name. Even the most liberal parent may swallow hard and ask her (them) to have counselling with an experienced psychologist who can explore those feelings before the teenager embarks on drastic hormone treatment.
Thats a loving reaction, in my book. Astonishingly, in some countries it would be illegal. Therapists are forbidden to try and find out if anything else may lie behind a young persons misery in their own body. According to trans activists, talking therapies are the same as conversion therapy, an abhorrent practice which puts pressure on a gay boy or girl to renounce their sexuality.
Stonewall, the LGBTQ campaign group, insists that only affirmation is acceptable. You are not allowed to suggest your child is confused or to point out that there has been an extraordinary increase in girls seeking to transition from female to male or that many of those girls have autism. Nor that some kids who think they are trans have been bullied for being gay.
I agree with Debbie Hayton, a transwoman and campaigner, who says that the denial of meaningful therapy for vulnerable youngsters is chilling. But loving parents who make the same objection are branded transphobic.
This is the background to the Governments U-turn in which it excluded trans people from legislation banning conversion therapy. The Prime Minister drew a crucial distinction, saying, There are complexities and sensitivities when you move from the area of sexuality to the question of gender ... I dont think its reasonable for kids to take decisions about their gender without a parents involvement.
Boris is right. It isnt reasonable and nor is it kind. Kids who are in a distressed state can fixate on one solution to all their problems. Society owes them more than a reckless rush down the clinic for hormones which will wreck their fertility.
How tragic that this personal matter should become a political football. Terrified of their ideological commissars, Labour MPs look like complete wallies as they refuse to confirm or deny whether a person with a penis can be a woman. Angela Rayners tortuous answer to that vexed question sounded like a stoned sociology lecturer speaking Swahili. Its encouraging to see women across the spectrum, from Mumsnet to radical feminists, uniting against this insulting nonsense.
Ironically, many trans people do not want all this aggro on their behalf. Its frightening. A wise friend of mine whose partner transitioned successfully says, Every family starts from a position of denial and sadness. Sometimes they are right, sometimes they are wrong. Exactly. Some children will turn out to be correct in believing they would feel more themselves as another gender. For others, gender dysphoria may have been a peg on which to hang all the neuroses which are so common in that difficult phase of life.
Those young people all deserve loving support and proper counselling. What they dont need is fearful affirmation as they make the biggest, potentially most irreversible, decision of their lives.
Much amusement here at Pearson Towers after a headache and feeling tired were added to the official list of Covid symptoms. Isnt that the chronic and irreversible condition called Being Over 50?
Before half the population decided to throw a Covid sickie (Cickie?), Sajid Javid said that he personally would first reach for the Nurofen and go into work. I should think so too. The Health Secretary has got a six-million-long hospital waiting list to tackle.
I wonder, is Mr Javid aware of the further delays that an ongoing Covid fixation is causing in the NHS? One surgeon emailed me to express his alarm. A 66-year-old patient had arrived in hospital for heart surgery. Just hours before the operation, the poor man tested positive for Covid. Although he was not displaying any serious symptoms except, possibly, feeling tired the operation was cancelled.
That patients risk of death from surgical intervention has just risen to 90 per cent from an estimated 30 per cent directly because of the delay, fumes my source. I cannot believe that so many allegedly intelligent people are unable to make a sound judgment on the risk-benefit ratio of what is now just a flu.
Covid is no longer likely to kill you. But hospitals cancelling your operation or urgent appointment may well. The NHS needs to get a grip. We have nothing to fear but the fearful.
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It's cruel to deny trans children the chance to think again - The Telegraph
What Happens When You Stop Taking Birth Control Pills – Livestrong
Eating a balanced diet and taking high-quality supplements can help support your body as you stop taking the pill.
Image Credit: LIVESTRONG.com Creative
What Really Happens to Your Body When examines the head-to-toe effects of common behaviors, actions and habits in your everyday life.
The side effects of starting hormonal birth control are pretty widely discussed. But there's a little more mystery about what happens to your body when stopping birth control.
Birth control pills, also known as oral contraceptive pills, are the second most common type of contraceptive method as of 2019 (the latest data available), per the Centers for Disease Control and Prevention (CDC). If you've been thinking about stopping birth control after being on the pill for years, you should know that it's safe to stop at any time, according to the Mayo Clinic. But you should expect your body to go through some changes.
Here's the scoop on the side effects of stopping birth control pills and tips for taking care of yourself as you make the transition.
When to Stop Birth Control Pills
There are several reasons why someone might want to stop using birth control pills. According to Felice Gersh, MD, ob-gyn and the founder/director of Integrative Medical Group of Irvine, those reasons include:
Your Period Could Become Irregular
While some people who menstruate go back to their normal periods soon after stopping birth control pills, other people may have irregular periods for a while.
"Even if ovulation resumes during the first cycle post-pill, there's no guarantee the next few cycles will be regular. In fact, it can take up to a year for their cycles to go back to regular," says Kerry-Anne Perkins, DO, ob-gyn and member of the medical review board of Women's Health Interactive. "This is true for both types of pills, progesterone or estrogen-free and combined hormonal, which has both estrogen and progesterone."
And if you took birth control in order to regulate your menstrual cycle, there's a chance that previous unpleasant period-related symptoms may make a return, she notes.
You may also notice a change in the flow and duration of your period, per the Cleveland Clinic. It may be longer and heavier birth control pills typically give you shorter and lighter periods.
Your Fertility Levels Could Be Lower
It's valid to have concerns about how your fertility may be affected by discontinuing birth control pills, especially if you are trying to become pregnant.
A July 2018 meta-analysis in Contraception and Reproductive Medicine found stopping contraceptive use doesn't significantly delay or negatively affect fertility.
But your fertility levels may also be lower than they were when you started taking birth control pills. "If you have been on birth control for many years, your fertility has naturally declined and may be significantly lower than when you started the birth control," Dr. Perkins says.
When stopping the pill, be sure to use a backup method of contraception if you aren't looking to get pregnant at all or right away, per the Cleveland Clinic.
You Could Lose or Gain Weight
The belief that oral contraceptives commonly cause you to gain weight is a longstanding one, per a January 2014 study in the Journal of Women's Health.
But researchers of the study found birth control pills weren't linked to short-term changes in weight or body composition after observing 150 people assigned female at birth (AFAB) with both normal weight and obesity who used oral contraception over three to four months.
Typically, the pill doesn't cause more than a pound of weight gain per year, according to the Cleveland Clinic.
There are chances that you can lose or gain weight after you stop taking the pill, though. "Some women retain water while on the pill, so if this is you, you may drop a couple of pounds after quitting it," Dr. Perkins says. "Others could retain water after quitting the pill, due to some temporary hormonal imbalances. Again, it shouldn't be more than a couple of pounds."
It's also possible to experience changes in appetite due to hormonal shifts, Perkins notes, that could in turn contribute to weight changes.
When to Talk to Your Doctor
Talk to your doctor if you have questions or concerns about what to expect when stopping birth control pills, per the Cleveland Clinic. That's also a good time to discuss how being off of the pill will affect any prior conditions you have.
You May Have Acne or Hair Loss
You have hormonal changes to thank for any adverse skin and hair-related side effects you may experience after you come off birth control pills. Quitting birth control pills leads to a temporary hormonal imbalance, according to Dr. Perkins.
"For example, acne is fairly common in the first few months post-pill," she says. Experiencing hair loss or a condition called hirsutism (excessive facial hair) is also possible.
You Might Experience Mood Shifts
Most people won't experience significant emotional changes related to stopping the pill; most of the effects are physical, per Jefferson Health. But if you experienced mood swings or emotional instability on birth control, those things may stop post-pill.
On the flip side, if you were prone to depression, anxiety and mood swings before using birth control pills, those conditions may return when you nix oral contraception, according to Oschner Health.
Your Sex Drive May Change
A September 2012 review in The Journal of Sexual Medicine found a small correlation between the use of hormonal contraceptives and decreased libido, however research shows there are mixed results overall on how hormonal birth control affects your sex drive.
If you experienced lower desire while on the pill, you could find yourself feeling more sexual than usual after you stop taking it. "After quitting the pill, you may also experience changes in your libido usually higher libido, especially around ovulation," Dr. Perkins says.
Stopping Other Types of Hormonal Birth Control
Here are some potential side effects of stopping other types of hormonal birth control, according to Dr. Perkins:
Tips to Help Make Stopping the Pill Easier
Many of the side effects of discontinuing your birth control pill are temporary, but there are things you can do to help ease them.
1. Take a High-Quality Multivitamin
A September 2016 study in The Journal of Clinical Endocrinology and Metabolism found an association between higher vitamin D levels and estrogen-containing contraceptive use among more than 1,600 people identified in the study as African American women.
It may be beneficial to focus on naturally increasing your nutrient levels after you're off the pill. Some ways to raise your vitamin D levels, per the Mayo Clinic, include:
Dr. Gersh also recommends supplementing if you can't fit enough crucial nutrients from your diet alone. "Taking a high-quality multivitamin is key. Be sure it contains methyl B12, methyl folate, selenium and the usual array of vitamins," she says. "Extra magnesium would be of benefit, along with omega-3s and vitamin D."
2. Finish Out Your Current Pill Cycle
While you can quit the pill cold turkey, it may be best to finish out your current pill pack before stopping altogether.
You can expect to have your period within a few days after stopping the pill if you stop in the middle of the current pill cycle, according to the Cleveland Clinic.
Try to finish out your current round of pills, if possible, to avoid messing with your period.
A balanced diet can help as you transition away from birth control pills. Eating well is especially important if your appetite is affected by stopping the pill. For example, you may experience cravings.
"Pay attention to those cravings and try to eat a healthy and balanced diet to minimize them, and you shouldn't have weight issues," Dr. Perkins says.
Original post:
What Happens When You Stop Taking Birth Control Pills - Livestrong
Adenomyosis Treatment Market Analysis and Demand with Future Forecast to 2029 | Bayer AG, Ferring BV, Johnson & Johnson, Novartis Political Beef…
The report titled Adenomyosis Treatment market offers a primary overview of the Adenomyosis Treatment industry covering different product definitions, classifications, and participants in the industry chain structure. The quantitative and qualitative analysis is provided for the global Adenomyosis Treatment market considering competitive landscape, development trends, and key critical success factors (CSFs) prevailing in the Adenomyosis Treatment industry.
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Some of the key players in the Global Adenomyosis Treatment Market are Company Coverage (Company Profile, Sales Revenue, Price, Gross Margin, Main Products, etc.):
Bayer AG, Ferring B.V, Johnson & Johnson, Novartis, Merck, Pfizer.
Global Adenomyosis Treatment Market Segmentation:
Market Segmentation: By Type
Anti-inflammatory drugsHormone medicationsOther
Market Segmentation: By Application
HospitalClinicOthers
This comprehensive report provides:
COVID-19 Impact
Report covers Impact of Coronavirus COVID-19: Since the COVID-19 virus outbreak in December 2019, the disease has spread to almost every country around the globe with the World Health Organization declaring it a public health emergency. The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Retro Scooters Market in 2022.
The outbreak of COVID-19 has brought effects on many aspects, like flight cancellations; travel bans and quarantines; restaurants closed; all indoor/outdoor events restricted; over forty countries state of emergency declared; massive slowing of the supply chain; stock market volatility; falling business confidence, growing panic among the population, and uncertainty about future.
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Table of Content (TOC):
Chapter 1 Introduction and Overview
Chapter 2 Industry Cost Structure and Economic Impact
Chapter 3 Rising Trends and New Technologies with Major key players
Chapter 4 Global Adenomyosis Treatment Analysis, Trends, Growth Factor
Chapter 5 Adenomyosis Treatment Application and Business with Potential Analysis
Chapter 6 Global Adenomyosis Treatment Segment, Type, Application
Chapter 7 Global Adenomyosis Treatment Analysis (by Application, Type, End User)
Chapter 8 Major Key Vendors Analysis of Adenomyosis Treatment
Chapter 9 Development Trend of Analysis
Chapter 10 Conclusion
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Adenomyosis Treatment Market Analysis and Demand with Future Forecast to 2029 | Bayer AG, Ferring BV, Johnson & Johnson, Novartis Political Beef...
Chinese medicine and the pursuit of a good night’s sleep – taosnews
Its mid-afternoon on a mild spring day at Artemisia Clinic in Taos. Dr. Clara Wetmore, a doctor of Oriental Medicine, is treating Amy Dondanville, who has difficulty sleeping. Soothing music plays and fragrant herbs in orderly rows surround the treatment table of the well-lit clinic.
Wetmore consults with Dondanville and then checks her pulse at various points on her body, asking questions in a quiet voice, How is your stress level? Energy level? She asks how much caffeine Dondanville consumes.
Dondanville is experiencing a high level of stress, having just returned to her job as a clinical social worker after being gone for three weeks. She reports that she is not sleeping well and feels more frantic, like she is running on adrenaline that causes her to crash. She has removed most caffeine from her diet, drinking just one cup of black tea a day.
While Dondanville relaxes on the treatment table, Wetmore places needles in various parts of her body: her forehead, wrist, midsection and lower legs. I place needles at specific points along the relevant or affected meridians, based on symptoms, presentation and pulse diagnosis. Each point has unique indications, and I pick the points that relate to or address the symptoms and underlying health concerns, Wetmore explained. Today, she is inserting needles to help calm the mind, as well as reduce racing thoughts, anxiety, pain and insomnia. As the needles are placed, Dondanville explains that shes not feeling any pain, although sometimes she experiences a sensation.
Wetmore uses another tool, known as an ear or auricular seed, which is a tiny stainless steel pellet with a latex-free adhesive patch. Ear seeds are a type of auriculotherapy rooted in Chinese medicine. They're meant to promote comfort and relaxation and have become very popular in the West in recent years, despite some disagreement among medical professionals as to their efficacy. Occasionally, Wetmore uses gold pellets, depending on the treatment, or even small pellets with crystals on the top that look like little earrings if brought in by a patient.
Wetmore cleans and disinfects the ear and then places the tiny pellets in specific spots on the left ear that are tender, indicating trouble somewhere in the body. Dondanville will wear them for a week, after which they fall out or she will remove them. The ear seeds do their work while in place, Wetmore says, and their effectiveness can be increased by periodically pressing on them. Right now, I am placing an ear seed to regulate the nervous system and treat an insomnia point," she explains. "I also checked the liver point, usually aggravated by stress but that spot wasnt tender, so I am moving on to the heart spot which is calming to the mind.
Dondanville is experiencing difficulty powering down and falling asleep, which is her most common sleep struggle, although she does sometimes wake up in the middle of the night and have a hard time going back to sleep. She usually comes in weekly, but since she has been out of town, this is her first appointment in almost a month. She says, Ive had chronic sleep problems since I was a kid; its always been a struggle for me. The practice of coming regularly allows me to connect with my body and speak to what is specifically happening with my digestion, sleep, mood and energy levels. The act of reflecting is helpful itself. When accessing treatment regularly, I find I can fall asleep with great ease, which I wasnt previously able to achieve.
Wetmore also gives Dondanville a Chinese herbal formula for sleep. At the beginning of treatment, she was taking three to four doses per night and that has been reduced to one or none. This is what I want for all my patients: to get to the point where their bodies remember how to sleep without external help, says Wetmore.
Dondanville has been seeing Wetmore for about two and a half years. She sought Wetmore out for help with another issue, but through the comprehensive check-ins done at each appointment, the two discovered the extent of Dondanvilles sleep disturbances. The practice of attending appointments and engaging in reflection has created a sense of mindfulness and awareness about what is happening outside appointments and brought a deeper sense of noticing about which routines and habits nurture my body and which ones harm them, reflects Dondanville.
When asked what advice she would give to people struggling with sleep problems, Dondanville recommends that people become aware of what content is stimulating to the brain in a negative way, whether it be watching TV, listening to audio recordings or scrolling on the phone.
According to a study by Harvard Medical School, the blue light emitted by smartphones "can affect your sleep and potentially cause disease." The study notes a well-known fact about the brain that the absence of light signals to the brain to shut down for sleep and the presence of light triggers wakefulness. As such, turning down any bright lights before bed can help people to achieve deeper sleep. Conversely, exposure to daylight upon waking can boost alertness and mood.
Wetmore added, Id suggest that people establish a routine that cues the body that it is time to move towards sleep, which might be stretching, taking a bath or shower, or applying cream to nurture the body.
Sleep disorders and effective treatment
Wetmore opened her practice five years ago. She earned a Master's of Science in Oriental Medicine degree from the Southwest Acupuncture College in Santa Fe and is licensed by the state and certified nationally. For the best results, she sees patients on a regular basis, but even a single treatment can help. One new patient who was skeptical of acupuncture came to see Wetmore to get help with her racing thoughts. Wetmore treated her with acupuncture, ear seeds and an herbal formula. When Wetmore saw the patient next, she had gone from sleeping for about an hour a night to sleeping seven hours. Sometimes its dramatic like that, and other times it can take weeks or months to see results like hers, says Wetmore.
More than 100 different types of sleep disorders have been identified, according to the Sleep Foundation. Wetmore sees many of them at her clinic. People come to me with sleep issues ranging all over the insomnia spectrum; some who cant fall asleep, some who cant stay asleep or wake up too early, some light sleepers, some with crippling nighttime anxiety, some who cant turn their minds off at night," she says. "Some patients sleep for a few minutes per night if at all some for a few hours and some just dont get quite enough for their particular needs. The causes range from trouble sleeping due to menopausal or perimenopausal hormone shifts, which account for about half of her patients, while others are dealing with stress, anxiety, trauma, grief, pain or other issues. Sometimes, there is no obvious cause.
Because sleep disorders are so unique to each individual, being able to tailor acupuncture treatments and herbal formulas to each patients needs is hugely important in my work, says Wetmore. My goal is to regulate the sleep cycle so that patients dont need to take herbs and supplements forever to get a good nights sleep. Its like giving a gentle nudge and reminder for the body to remember how to do such a fundamental and necessary regenerative process on its own. Another advantage is that I spend a lot of time with each patient, so I really get to know each persons life, physical health and emotional health, giving me the insight to treat very specifically.
As part of her approach, Wetmore checks for any medications being taken by the patient to make sure there wont be interactions between the medications and herbs she recommends for sleep. In addition to making recommendations about nutrition, Wetmore refers patients to other needed services, such as therapy, meditation, exercise, primary care and other physicians.
When asked how her approach is different than a medical doctors might be, Wetmore said, In some ways, my approach probably isnt all that different than that of Western medicine; were all trying to help people feel better, and are using the tools, knowledge and skillsets we have. I have tremendous respect for my medical colleagues, and although folks dont always expect it, Im very much in support of Western medicine and science, and love to work in tandem with my patients other providers.
The questions of how much sleep we need as humans and how the lack of sleep impacts our health are the subjects of numerous studies over the past few years. In his 2017 book, Why We Sleep, Matthew Walker, Ph.D., professor of neuroscience and psychology at UC Berkeley and the director of the Center for Human Sleep Science, reports that two-thirds of the adults in developed nations do not get the full eight hours of recommended sleep. Through his research, he has pioneered work showing that insufficient sleep depresses the immune system, doubles risk of cancer, adds to weight gain and is a key factor in whether or not a person will develop Alzheimers disease. To find out more and see tips for better sleep, visit masterclass.com/articles/matthew-walker-on-improving-sleep-quality. There are also several free podcasts featuring Walker that delve into his research.
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Chinese medicine and the pursuit of a good night's sleep - taosnews
Osteoporosis Treatment Market See Huge Growth for New Normal | Merck and Co AG, Novartis AG, Eli Lilly and Company Bloomingprairieonline -…
New York, United States A2Z Market Research published new research on Global Osteoporosis Treatment covering the micro-level of analysis by competitors and key business segments (2022-2029). The Global Osteoporosis Treatment explores a comprehensive study on various segments like opportunities, size, development, innovation, sales, and overall growth of major players. The research is carried out on primary and secondary statistics sources and it consists of both qualitative and quantitative detailing.
Some of the Major Key players profiled in the study are Merck & Co AGNovartis AGEli Lilly and CompanyAmgen, Inc.Allergan PlcActavis Plc.Pfizer, Inc.GlaxoSmithKline Pharmaceutical Ltd.F. Hoffmann La Roche Ltd.Novo Nordisk A/STeva Pharmaceuticals Industries Ltd.
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Various factors are responsible for the markets growth trajectory, which are studied at length in the report. In addition, the report lists down the restraints that are posing threat to the global Osteoporosis Treatment market. This report is a consolidation of primary and secondary research, which provides market size, share, dynamics, and forecast for various segments and sub-segments considering the macro and micro environmental factors. It also gauges the bargaining power of suppliers and buyers, threat from new entrants and product substitutes, and the degree of competition prevailing in the market.
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Manufacture by region: This Global Osteoporosis Treatment report offers data on imports and exports, sales, production and key companies in all studied regional markets
Global Osteoporosis Treatment Market Segmentation:
Market Segmentation: By Type
BisphosphonatesParathyroid Hormone TherapyCalcitoninSelective Estrogen Inhibitors Modulator (SERM)
Market Segmentation: By Application
HospitalsClinicOthers
Market Segmentation: By Geographical Analysis
The Middle East and Africa (GCC Countries and Egypt)North America (the United States, Mexico, and Canada)South America (Brazil etc.)Europe (Turkey, Germany, Russia UK, Italy, France, etc.)Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)
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The cost analysis of the Global Osteoporosis Treatment Market has been performed while keeping in view manufacturing expenses, labor cost, and raw materials and their market concentration rate, suppliers, and price trend. Other factors such as Supply chain, downstream buyers, and sourcing strategy have been assessed to provide a complete and in-depth view of the market. Buyers of the report will also be exposed to a study on market positioning with factors such as target client, brand strategy, and price strategy taken into consideration.
Key questions answered in the report include:
Table of Contents
Global Osteoporosis Treatment Market Research Report 2022 2029
Chapter 1 Osteoporosis Treatment Market Overview
Chapter 2 Global Economic Impact on Industry
Chapter 3 Global Market Competition by Manufacturers
Chapter 4 Global Production, Revenue (Value) by Region
Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions
Chapter 6 Global Production, Revenue (Value), Price Trend by Type
Chapter 7 Global Market Analysis by Application
Chapter 8 Manufacturing Cost Analysis
Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers
Chapter 10 Marketing Strategy Analysis, Distributors/Traders
Chapter 11 Market Effect Factors Analysis
Chapter 12 Global Osteoporosis Treatment Market Forecast
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Osteoporosis Treatment Market See Huge Growth for New Normal | Merck and Co AG, Novartis AG, Eli Lilly and Company Bloomingprairieonline -...
Are COVID-19-Linked Arrhythmias Caused by Viral Damage to the Heart’s Pacemaker Cells? – Weill Cornell Medicine Newsroom
The SARS-CoV-2 virus can infect specialized pacemaker cells that maintain the hearts rhythmic beat, setting off a self-destruction process within the cells, according to a preclinical study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and NYU Grossman School of Medicine. The findings offer a possible explanation for the heart arrhythmias that are commonly observed in patients with SARS-CoV-2 infection.
In the study, reported March 8 in Circulation Research, the researchers used an animal model as well as human stem cell-derived pacemaker cells to show that SARS-CoV-2 can readily infect pacemaker cells and trigger a process called ferroptosis, in which the cells self-destruct but also produce reactive oxygen molecules that can impact nearby cells.
This is a surprising and apparently unique vulnerability of these cellswe looked at a variety of other human cell types that can be infected by SARS-CoV-2, including even heart muscle cells, but found signs of ferroptosis only in the pacemaker cells, said study co-senior author Dr. Shuibing Chen, the Kilts Family Professor of Surgery and a professor of chemical biology in surgery and of chemical biology in biochemistry at Weill Cornell Medicine.
Arrhythmias including too-quick (tachycardia) and too-slow (bradycardia) heart rhythms have been noted among many COVID-19 patients, and multiple studies have linked these abnormal rhythms to worse COVID-19 outcomes. How SARS-CoV-2 infection could cause such arrhythmias has been unclear, though.
In the new study, the researchers, including co-senior author Dr. Benjamin tenOever of NYU Grossman School of Medicine, examined golden hamstersone of the only lab animals that reliably develops COVID-19-like signs from SARS-CoV-2 infectionand found evidence that following nasal exposure the virus can infect the cells of the natural cardiac pacemaker unit, known as the sinoatrial node.
To study SARS-CoV-2s effects on pacemaker cells in more detail and with human cells, the researchers used advanced stem cell techniques to induce human embryonic stem cells to mature into cells closely resembling sinoatrial node cells. They showed that these induced human pacemaker cells express the receptor ACE2 and other factors SARS-CoV-2 uses to get into cells and are readily infected by SARS-CoV-2. The researchers also observed large increases in inflammatory immune gene activity in the infected cells.
The teams most surprising finding, however, was that the pacemaker cells, in response to the stress of infection, showed clear signs of a cellular self-destruct process called ferroptosis, which involves accumulation of iron and the runaway production of cell-destroying reactive oxygen molecules. The scientists were able to reverse these signs in the cells using compounds that are known to bind iron and inhibit ferroptosis.
This finding suggests that some of the cardiac arrhythmias detected in COVID-19 patients could be caused by ferroptosis damage to the sinoatrial node, said co-senior author Dr. Robert Schwartz, an associate professor of medicine in the Division of Gastroenterology and Hepatology at Weill Cornell Medicine and a hepatologist at NewYork-Presbyterian/Weill Cornell Medical Center.
Although in principle COVID-19 patients could be treated with ferroptosis inhibitors specifically to protect sinoatrial node cells, antiviral drugs that block the effects of SARS-CoV-2 infection in all cell types would be preferable, the researchers said.
The researchers plan to continue to use their cell and animal models to investigate sinoatrial node damage in COVID-19and beyond.
There are other human sinoatrial arrhythmia syndromes we could model with our platform, said co-senior author Dr. Todd Evans, the Peter I. Pressman M.D. Professor of Surgery and associate dean for research at Weill Cornell Medicine. And, although physicians currently can use an artificial electronic pacemaker to replace the function of a damaged sinoatrial node, theres the potential here to use sinoatrial cells such as weve developed as an alternative, cell-based pacemaker therapy.
Many Weill Cornell Medicine physicians and scientists maintain relationships and collaborate with external organizations to foster scientific innovation and provide expert guidance. The institution makes these disclosurespublic to ensure transparency. For this information, see profiles for Dr. Todd Evans, and Dr. Robert Schwartz.
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Are COVID-19-Linked Arrhythmias Caused by Viral Damage to the Heart's Pacemaker Cells? - Weill Cornell Medicine Newsroom
U.S. STEM CELL, INC. Management’s Discussion and Analysis of Financial Condition and Results of Operations (form 10-K) – Marketscreener.com
The following is management's discussion and analysis ("MD&A") of certainsignificant factors that have affected our financial position and operatingresults during the periods included in the accompanying financial statements, aswell as information relating to the plans of our current management. This reportincludes forward-looking statements. Generally, the words "believes,""anticipates," "may," "will," "should," "expect," "intend," "estimate,""continue," and similar expressions or the negative thereof or comparableterminology are intended to identify forward-looking statements. Such statementsare subject to certain risks and uncertainties, including the matters set forthin this report or other reports or documents we file with the Securities andExchange Commission from time to time, which could cause actual results oroutcomes to differ materially from those projected. Undue reliance should not beplaced on these forward-looking statements which speak only as of the datehereof. We undertake no obligation to update these forward-looking statements.
The following discussion and analysis should be read in conjunction with ourfinancial statements and the related notes thereto and other financialinformation contained elsewhere in this Form 10-K
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Comparison of Years Ended December 31, 2021 and December 31, 2020
Cost of sales consists of the costs associated with the production of MyoCathand test kits, product costs, labor for production and training and lab andbanking costs consistent with products and services provided.
Cost of sales was $52,030 in the year ended December 31, 2021 compared to$64,117 in the year ended December 31, 2020. The decrease is due to the decreasein revenues.
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Epithelial Cell Culture Media Market to exceed USD 303040.33 thousand by 2028 says, The Insight Partners – Digital Journal
According to The Insight Partners new research study on Epithelial Cell Culture Media Market Forecast to 2027 COVID-19 Impact and Global Analysis by Product Type and End User, the market is expected to reach US$ 303,040.33 thousand by 2028 from US$ 128,155.95 thousand in 2020; it is estimated to grow at a CAGR of 11.4% from 2021 to 2028.
Certain age-related diseases, abnormalities, and trauma damage the tissues and organs. Regenerative medicines have the potential to replace or heal tissues and organs, along with normalizing congenital defects. In the last decade of the century, tissue engineering techniques have emerged impressively, and they are now being employed in broader areas of regenerative medicine. Thus, it has now become possible to use these techniques in the development of clinical therapies for the maintenance, repair, replacement, and enhancement of biological functions. Further, the regenerative medicines developed using cell-based models can potentially assist researchers in the early intervention of degenerative diseases and traumatic injuries.
Download sample PDF Copy of Epithelial Cell Culture Media Market study at: https://www.theinsightpartners.com/sample/TIPRE00022539/
PromoCell GmbH; Merck KGaA; ATCC; AXOL Bioscience Ltd.; Thermo Fisher Scientific, Inc.; Bio-Techne Corporation; Celprogen, Inc.; Lonza Group AG; HiMedia Laboratories; and Cell Biologics, Inc. are among the leading companies operating in the epithelial cell culture media market.
Geographically, the epithelial cell culture media market is segmented into North America, Europe, Asia Pacific (APAC), the Middle East and Africa (MEA), and South and Central America (SCAM). North America held the largest market share in 2020. In 2020, the US held the largest share of the market in North America. The market growth in North America is attributed to the key driving factors such as the presence of various market players and increasing demand for cell culture products from biopharmaceutical and biotechnology companies.
Human amniotic epithelial cells (hAECs) from placental tissues have gained substantial attention in the field of regenerative medicine owing to their proliferative capacity, easy access, multilineage differentiation potential, and safety. These are perinatal stem cells that have embryonic stem cell-like properties and the capability to be induced to differentiate. Thus, a growing focus on bringing advancements in regenerative medicine is likely to boost the adoption of epithelial cell cultures, thereby bolstering the demand for the respective culture.
Inquiry Before Buying on epithelial cell culture media market at: https://www.theinsightpartners.com/inquiry/TIPRE00022539/
Below is the list of the growth strategies done by the players operating in the epithelial cell culture media market:
In May-21 Bio-Techne has released MimEX GI, a new product line for generating 3-dimensional (3-D) gastrointestinal tissue on a 2-D surface.
In Sep-2020 Axol Bioscience and Censo Biotechnologies Announce Merger. The newentitywould become a global leader in the iPSC-based neuroscience, immune cell, and cardiac simulation industries for drug development and screening.
The report segments the epithelial cell culture media market as follows:
By Product Type
Human Mammary Epithelial CellsBronchia/Trachea Epithelial CellsRenal Epithelial CellsOthers
By End User
Biopharmaceutical CompaniesAcademic and Research Laboratories
Interested in Purchasing epithelial cell culture media market Report? Click here @ https://www.theinsightpartners.com/buy/TIPRE00022539/
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Epithelial Cell Culture Media Market to exceed USD 303040.33 thousand by 2028 says, The Insight Partners - Digital Journal
Life Extension and Anti-Aging Have a Branding Problem – Lifespan.io News
It seems bizarre that in 2022, some biotech companies interested in doing something about aging are still saying that they are not. Cellular rejuvenation seems to be the latest buzzword and an attempt to rebrand and escape the stigma of anti-aging.
Recently, researchers at the Salk Institute, in collaboration with Genentech, showed that they can safely and effectively reverse aging in old mice by resetting their cells to a more youthful state using Yamanaka factors.
Genentech, a large Roche subsidiary biotech company, is focusing on cellular rejuvenation using partial cellular reprogramming. It could be set to become a future rival of Altos Labs.
Earlier this year, Altos Labs made its debut, bringing $3 billion in funds and an impressive roster of researchers to focus on cellular reprogramming. Despite media suggestions that it is a longevity or anti-aging company, Altos is adamant that it is not.
Instead, Altos has positioned itself as a cellular rejuvenation reprogramming company. Genentech also looks like it might follow a similar path and double down on the cellular rejuvenation angle, avoiding coming out and saying that it is an anti-aging or longevity company. Given that both companies are working on cellular rejuvenation, which is very much relevant to aging, it might seem somewhat strange for them to claim to be uninvolved in it.
Why are they doing this? Its because life extension and anti-aging have a branding problem. There are a few reasons why.
Some companies are sidestepping the whole issue by simply going after diseases without drawing focus on the age reversal aspect of what they are doing. The FDA is not going to approve a trial to reverse aging, so the logical step for a number of companies is to instead focus on a particular disease and aim to demonstrate disease modification. The FDA is unlikely to take issue with age reversal or rejuvenation technology if it is demonstrably effective against a specific age-related disease. This is why an increasing number of companies are taking this route to get through clinical trials. Once approved the idea would be that off label use would occur.
The life extension community unfortunately does have a reputation for being long on promises and short on delivery. With what is now decades of research, there are still no effective therapies against aging.
Of course, science takes time, and a lot of progress is being made in our fundamental understanding of aging as well as the steady slog to translate the research from animals to humans. However, public perception is based on results, and so far, nothing has turned back aging enough in people to grab public attention.
This is also not helped by otherwise earnest researchers in our community sometimes fueling hype and exaggerating the impact of their current research. While it is perfectly understandable to be excited about ones own research, some researchers do sometimes make claims that go beyond the data.
This is likely due to their hopes of attracting funding and grants, but it can be harmful to the image of the field when the hype does not meet the reality.
Another factor that is likely playing a part in this rebranding is the sad fact that our field is filled with snake oil salesmen out to make a quick buck.
Alongside the legitimate researchers doing fine scientific work in the lab, there are also plenty of hucksters hiding in the community. These people prey on people who lack the knowledge to discern credible science from pseudoscience and peddle worthless products, much like the snake oil salesmen of the Old West.
One example is a biotech company evading the FDA by setting up shop in a country with few or no regulations. This sort of company makes bold claims yet never delivers on those claims in practice, using poorly designed experiments and tiny cohorts that are statistically irrelevant.
Worse, such a company might not even attempt to publish data in credible scientific journals, instead choosing to make bold claims on personal websites and publishing dubious data that has not gone through peer review. This sort of company sometimes offers treatments in areas with little or nonexistent regulations. Its customers are gambling with their lives in the hope that whatever the company is offering is as described and actually works as intended; they could be receiving a fake, saline injection or something worse.
Another example is a supplement peddler who sells expensive supplement blends with flashy names, which, on inspection, turn out to be commonly available herbs and minerals that are mixed and sold at a high mark-up with questionable or no supporting data. These sorts of people have plagued our community and given the field a reputation for snake oil. Therefore, it is no surprise that these new, well-funded companies working on cellular rejuvenation want nothing to do with it.
It will take a group effort to clean up the perception of our field to hopefully make these new companies more comfortable in associating with it. There are a few things that each of us can do to help.
While it will be some years yet before a comprehensive suite of therapies to end age-related diseases is here and available, and the hucksters are peddling their wares right now, you can arm yourself with knowledge and protect yourself and our community from these people. Learn to evaluate science rather than taking things at face value, and avoid expensive scams and bad science.
Here are some useful questions to consider when reading an article, looking at claims made by supplement makers, or evaluating any science in general.
Legitimate claims will undergo peer review first. Shady companies not backing up their claims with published data are a dime a dozen; do not be fooled by them. Also, pay attention to the source of the news; press releases, associated companies, and obscure websites are poor sources. The bottom line is that any company making claims about its product should be able to back those claims up with published research in a respected journal.
Credible research is generally published in credible, peer-reviewed journals with transparent and clear details of experiments so that others may attempt to replicate their results. When evaluating a claim, always see if it is published and if anyone else has successfully, independently replicated the results. Also, ensure that any independent results are indeed independent and that there is no link between the original group and the study replicating the results.
Similar to the above; a company or research team worth its salt will have a trail of evidence documenting research and development efforts that likely go back for years or even decades. If a company appeared from nowhere and has no historical record of its research, this is a huge red flag.
Learn to evaluate how statistically significant results are. Did a test involve a single mouse or a person, or did it involve hundreds or even thousands of test subjects to reach its conclusion? The smaller the study, the higher the statistical noise and the greater the effect that outliers can have on the average. Large test groups offer the most stable and accurate data, and small, single-patient studies are, for the most part, not useful.
Beware a company that tests on a single candidate and claims that a supplement or therapy works. A credible company may start with a small pilot study but ultimately expands into larger-scale studies in order to prove safety and efficacy.
Investigate and check their academic pedigrees. Having a Ph.D. is not required to conduct great science, but, in general, a researcher of any worth will have peer-reviewed publications with lots of citations and a good reputation in academia.
Even when there is published data, make sure you find out where the funding comes from. Studies on a patented supplement that are funded by the patent holder are a serious red flag and should be viewed with extreme caution.
Claims of being suppressed or somehow blocked by the government or other entities is a common tactic used by scammers. A scammer might claim to be a misunderstood researcher who just wants to help, and a supplement maker in trouble with the FDA for making false claims might say that it is simply being misinterpreted. This is base trickery; dont fall for it.
If it sounds too good to be true, then the chances are that it probably is. Credible science is always appropriately cautious and never overly affirmative; if someone is way too positive, this is a red flag.
The appeal to the ancients logical fallacy is commonly used to convince and part people from their money. The ancients used certain supplements, so they must work is a common tactic used to sell things. The truth is that while our ancestors were indeed clever and creative in many ways, not all their ideas were wise; indeed, many of the things they believed were dead wrong and even dangerous. This is a commonly used tactic in the supplement and diet industries.
This is the appeal to nature fallacy, another common sales tactic that takes advantage of the biases we as humans have and our inclination to think that everything natural is good. A quick review shows us that what is natural is not always a good thing: tidal waves, earthquakes, venomous snakes, diseases, and aging are all natural, but they are most certainly not desirable.
This is, of course, only a short checklist of things to watch out for; if a claim raises these flags, then its a good idea to be highly dubious about its credibility.
The snake oilers will be with us for quite a while, but by working together as a community and thinking critically about claims, we can help filter these people out and ultimately clean up the field for the benefit of legitimate scientists working on the real solutions to aging that will benefit us all.
Another consideration is that as more therapies enter clinical trials and high-quality data arrives, the hucksters will be steadily ousted. Ultimately, once therapies that have passed through the proper trial process arrive, most people will not wish to risk their health and money on hucksters.
The reputation of the field has improved massively in the last decade, but there is much that we can all do to improve it further.
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Life Extension and Anti-Aging Have a Branding Problem - Lifespan.io News
Raiany Romanni on the Ethical Aspects of Life Extension – Lifespan.io News
Raiany Romanni is a Harvard Kennedy Fellow in Effective Altruism, an A360 Scholar, a Stanford Existential Risk Fellow, and a bioethicist. She is currently working on a non-fiction book aimed at catalyzing the ethics of longevity research while suggesting that aging is the costliest of all human diseases. Raiany says that of particular interest to her works is the human proclivity towards death-embracing narratives and its harmful effects on economies and societies.
The easy answer would be to point at my degree in bioethics from Harvard Medical School. The more accurate answer, however, would be to say that I became a bioethicist because Ive always been obsessed with life. What does it mean to be alive or dead? How have the meanings we ascribe to life evolved over the centuries? My training in philosophy seemed insufficient to address these questions. Theory is only useful if we can translate it to the suffering of real persons and to the emerging world of converging technologies which will transfigure the meaning of life.
We need bioethicists around because what is right isnt always intuitive, and it takes rigorous work to understand how best to augment human flourishing. As a bioethicist, I try to occupy myself with what is quantifiably good for human societies. I recently became a Harvard Kennedy Fellow in Effective Altruism (EA) and believe EA supplements the work of bioethics by encouraging counterintuitive questions like What if we treated the fundamental processes of aging, instead of Alzheimers? Would that objectively be a better use of our limited resources towards our existing goal of extending human healthspan?
We currently spend a little over 1% of all National Institutes of Health funding on the fundamental processes of aging. Meanwhile, some 80% of an average individuals medical expenses occur past the age of forty. Theres a significant mismatch here.
For all our medical breakthroughs, two things have remained rather constant throughout history: human lifespan and human healthspan. For every human life, we have consistently recorded one death, at a maximum age of 122. At around 25, we begin to decay. These two facts often overshadow the remarkable fact that weve engineered a doubling in average life expectancy over the past century.
The eradication of smallpox and polio and the relative control of nearly all infectious diseases was hardly insignificant. But the fact that we havent doubled the number of years a human can live let alone in good health legitimately contributes to the publics disbelief that scientists may be able to achieve this.
Were wired to appreciate the world through an availability heuristic: the examples we can most readily recall often guide our moral reasoning. So, its not altogether irrational that people should question our ability to reverse aging. Only a small fraction of the worlds population devotes their time to reading dense, scientific papers, which indeed prove that several mechanisms of aging can be quite easily manipulated. And only a small fraction of the worlds population wants to deal with the ethical challenges that accompany this fast-arriving revolution.
Weve built so much of our infrastructure around the idea of death and gradual decay that most of us would rather just reject the messy possibility of a longer, healthy life. It seems like too much work. With radical health extension, what do we do about incarceration or monogamy? These are difficult questionsbut certainly worth answering.
As a myth, the notion that death is a progress-furthering entity, and aging a necessary parcel of life, made sense. For millennia, it was a helpful narrative, needed to cope with the gruesomeness of bodily decay, when we could do nothing about it. We certainly didnt have the converging technologies, when the Black Plague killed a good half of the European population, to hope otherwise. In that context, religion, too, was a rational choice.
Responding from a place of recognition of the publics rationality, rather than the (misguided) assumption that people reject longevity research because they are irrational, is helpful, I think. People rely on heuristics to do their own scanning of the world, and those can be misleading at times, but I like to believe that if offered a full picture of the problem of aging, a good portion of us would be convinced it must be solved.
The ethics, in my view, cant be considered without consideration of the economic, downstream effects. If you think ethics ought to be addressed without regard to economic impact, then you cant talk about equitable distribution, affordability, or even the creation of these therapies in the first place (which, whether theorists like it or not, requires money).
We cant reduce the ethics to just economics: a mistake often made when bioethicists assume that biotechnologies should only be pursued if they can be made immediately affordable. But we also cant undermine the fact that increased capital can translate directly into increased human flourishing.
To be relevant (i.e., not constantly outpaced by the science), I think bioethicists must learn to consider technologies in principle: to assume that they could work, could be quite equitably distributed (not in ideal, Rawlsian worlds, but in the flawed societies weve got), and could go through all phases of a clinical trial. Then, we get to truly interesting questions.
If we could engineer ourselves out of aging, would we risk engineering ourselves, too, out of the meaning of human life? The answer, I think, is yes: but only as much as we engineered ourselves out of the meaning of life in the Stone Age, when to be human meant to hunt and gather for ones every mealuntil it didnt.
First, I think the wealthy should be rewarded for funding these life-saving technologies towards clinical safety, and eventually towards governmental adoption. If there is no reward, there are no therapies, no trickle-down effect, no decreased human suffering.
The sad part, for me, is that venture capital alone, absent governmental funding, is going to take decades, if not centuries, longer to deliver commercial-grade aging therapies. Imagine for a minute that for some odd reason governments decided during the COVID-19 pandemic that they would leave it all to private capital. Wed probably get to a vaccine, and to some level of social relief, but not within the span of several months.
Again, only about 1% of all National Institutes of Health funding goes to fundamental aging research. So, at least we have people like Bezos and Thiel and Zuckerberg interested in disrupting the healthcare system. I hope they do: wed all benefit from it.
Im interested in increased human flourishing, and diminished suffering. Whether a civilization that could repeatedly reset its biological clock could achieve both is a question at least worth pursuing.
Weve built our entire infrastructure to sustain rather than solve the problem of aging. Nick Bostroms The Fable of the Dragon Tyrant is a brilliant caricature of this problem. If we could always return to a more youthful state say, like Turritopsis dohrnii I think wed be incredibly productive. The US currently spends nearly half its federal budget every year on the effects of aging. Imagine the problems we could solve if that funding were freed up, and there will be no shortage of problems.
But then, would innovation take place at a similar rate? Some studies show that people are most productive in their fortieswhen theyve lived enough years to know what they are doing, but not enough that their cells cant remember what they used to be. If the same person were in charge of innovation, say, through a two-hundred-year health-span, would they be prone to founding startups, and coming up with fresh solutions to old problems? I think wed need to actively train this new civilization on the importance of remaining nimble, and not carrying biases. This may not be so easily achieved, but if the alternative is murdering these people, or burdening our healthcare systems, I think we all agree it would be well worth the effort.
So, yes, if we engineer ourselves out of aging, we will most likely engineer ourselves, too, out of the meaning of life. This would be neither the first nor the last time in history this happened. Were the storytellers. The difference, in this century, is that the story is going to evolve at an unprecedented pace.
The cause isnt ours: its humanitys. Health extension is a more effective way of doing what weve been doing all along: namely, extending life and health, and delaying death and decay.
Soon, our populations will begin to shrinkJapan, for example, is set to lose 21 million people by 2050. And, as Peter Diamandis writes, in technologically advanced societies, where misdistribution and not scarcity of resources is the issue, large populations are an asset. The more minds working towards human and planetary flourishing, the better.
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Raiany Romanni on the Ethical Aspects of Life Extension - Lifespan.io News
Essex National Heritage Area Gets Life Extension with Approval of Federal Spending Law – WHAV News
Essex National Heritage Area Chief Executive Officer Annie C. Harris.
The Essex National Heritage Area, created in 1996 as an unusual national park, will continue to receive federal financial support this year as legislators recently approved a spending bill continuing the designation until 2023.
Federal law authorizing the secretary of the interior to provide money to the Essex National Heritage Area expired last Sept. 30. The countywide park emphasizes the historical significance of the 500-square-mile region, covering 34 cities and towns.
Two and a half decades after its creation, the Essex National Heritage Area continues to serve as a cultural and economic driver for working families throughout the region and for communities like Lawrence, Haverhill and Andover, said Congresswoman Lori Trahan in a joint legislative statement.
Sen. Edward J. Markey said he is glad the spending bill heeded our call to extend the Essex National Heritage Areas authorization, enabling it to receive the federal funds it needs to continue to support partnerships between Massachusetts communities and the National Park Service to preserve our regional treasures. He added he will continue fighting in the Senate to lift the funding cap for the Essex National Heritage Area and extend its authorization even further until 2036.
U.S. Rep. Seth Moulton added, The Essex National Heritage Area brings hundreds of thousands of people to northeast Massachusetts, where they spend millions of dollars and create thousands of jobs in our community.
Last year, Sens. Markey and Elizabeth Warren and Reps. Moulton and Trahan introduced legislation to eliminate the total funding cap for the Essex National Heritage Area and extend its authorization by 15 years to 2036. In November 2021, the Senate Energy and Natural Resource Committee passed a version of the bill that would raise the heritage areas funding cap to $22 million and extend its authorization to 2036.
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Essex National Heritage Area Gets Life Extension with Approval of Federal Spending Law - WHAV News
14 Easy Ways to Extend and Enhance Your Life, Starting Now – Men’s Health
The average guy lives to be 75 years old. Thats up about five years from what our life expectancy was two decades ago. The even better news: There are also fairly easy ways to make the most of the time you've already gainedand probably earn even more of it. We're talking about small lifestyle or outlook changes with big impacts. Because your real goal shouldn't be just to live longer, but to feel more vital.
To prove it, Mens Health asked a fleet expertseveryone from longevity and healthy aging researchers, to top athletes and cultural iconsto share their own practical advice for carpe deiming. Here are 14 easy ways to help you extend and enhance your life. Starting right now.
Exercising random acts of kindness and donating time to good causes enhance social integration while improving self-gratification. Those factors, plus the stress relief those things create, can have profound longevity benefits.
James Muruthi, Ph.D., Director of the Healthy Aging Lab at University of Oregon.
Feed on Fiber
Eating fibrous foods like yams and asparagus and polyphenol rich foods like olive oil, coffee, tea, and dark colored fruits and vegetables produces a hugely beneficial phenomenon called mitochondrial uncoupling in our cells. Healthy old people have the most uncoupled mitochondria. This mitochondrial energy processing trick is the golden ticket to increasing energy levels, losing weight and yes, extending your lifespan.
Steven Gundry, M.D., former cardiac surgeon and author of The Longevity Paradox: How to Die Young at Ripe Old Age and Unlocking the Keto Code.
Respond Instead of React
"Slowing aging starts with slowing down. Cultivate a space between a stimulus (stress, unhealthy food cravings) and your response by going for a walk or taking ten deep breaths through your nose and out of your mouth. These activities will activate the vagus nerve and parasympathetic nervous system, which will allow you to make choices from a place of clarity and certainty, helping you make healthier choices for your body in the long run.
Kien Vuu, M.D., clinical professor at UCLA Health and author of Thrive State: Your Blueprint for Optimal Health, Longevity, and Peak Performance.
People with severe mental health disorders tend to die earlier than the general population, and taking charge of your mental wellbeing can do wonders for life extension. One way to start: Answer these questions right now: 1) How is my mood? (Answer with an emotion. Am I happy? Sad? Angry? Upset? Irritable? Euphoric? 2) Is this your baseline or normal mood? (Answer yes or no, because we all have off days. If its an off day, reevaluate later in the week or the following week.) 3) Am I content with feeling this way? If no, reach out to someone you trust to talk about it.
Kalisha Bonds Johnson, Ph.D., R.N., professor at Emory Universitys School of Nursing, director of special programs at Black in Gerontology & Geriatrics.
Cold exposure releases noradrenaline, a hormone that boosts cell performance. Due to the disappearance of thermal stress thanks to air conditioning and central heating, our bodys thermoregulatory system isnt getting enough of the exercise or stimulation needed to feel invigorated and perform better. Through daily cold water immersion, you can boost your bodys natural repair and recovery response thats central to slowing aging.
Rose Anne Kenny, M.D., geriatrician and author of Age Proof: The New Science of Living a Longer and Healthier Life.
I come from an Indian background where we were taught Sanskrit chanting at a very young age. It requires a lot of memorization and involves rituals and practices. We chant a lot of verses, which can be like longform poems. It seems to have a meditative effect and its a form of memory rehearsal, which can keep the brain healthy as you age. Reading complicated fiction or non-fiction books can have a similar benefit because it challenges your brain to track the characters and the plot over time.
P. Murali Doraiswamy, M.D., director of the Neurocognitive Disorders Program at Duke University School of Medicine.
I eat fruits and treat myself to an ice cream once per month. But make no mistake about itexcess sugar in all its forms is poison. It is always one of the first things I recommend eliminating for those interested in longevity. To lessen your intake of sugar, I recommend avoiding all processed foods and sugary drinks.
Sergey Young, longevity investor and author of The Science and Technology of Growing Young.
Tooth decay and gum disease are chronic infections which our immune systems can never quite get on top of. Thorough brushing and daily flossing will help prevent these, and therefore prevent chronic inflammation, one of the key drivers of aging.
Andrew Steele, Ph.D., physicist and author of Ageless: The New Science of Getting Older Without Getting Old.
Words of affirmation are crucial to my wellbeing, its important to start my day off with positivity. Each day I am also intentional about taking personal time for myself. That could be listening to an old vinyl record or simply embracing silence in an effort to calm my mind and give peace to my thoughts."
Matt Horn, Pitmaster of Horn BBQ in Oakland, CA, and author of the Horn Barbecue cookbook, out April 12.
My dad told me early on: Control what you can control and what you cant control? You cant let it bother you. One area I can just about control: raising my children, who motivate me every day. To be a better man, better dad, better human."
Trent Williams, NFL offensive tackle, cancer survivor, and subject of the new documentary, Silverback: The Trent Williams Story, out now.
I work so hard, and over time I'd developed strange guilt around resting. But there's nothing better than an hour on the couch. Everything and everyone will still be waiting for you when you get up. It's fine."
Jason Reynolds, bestselling author of more than a dozen young adult books, including his latest, Aint Burned All the Bright.
I grew up with the Gurkha and Special Forces heritage, so its all about discipline, being respectful to others, never give up on the mission you are going for, stay humble, and keep training. I always try and stay fit. That might be in the form of climbing mountains or when Im not on the mountains, I do regular work outs. One of my secrets is burpeesbut a lot of themabout 300 in one go.
Nimsdai Purja, star of the documentary 14 Peaks (Netflix), and author of Beyond Possible: One Man, Fourteen Peaks and the Mountaineering Achievement of a Lifetime.
Waiting for something wonderful can be painful if you look at it that wayWhy dont I have that promotion yet? Why cant I afford the house I want? Or it can be anticipatory joy, like waiting for Santa as a child, reveling in the hope that you will receive wonderful gifts. And when things have passed out of existence, you still get to enjoy them in the presentRemember how wonderful that vacation was? What it felt like to sail, or to ride a roller coaster? But you only can enjoy them if you are okay with the present.
Mary-Frances OConnor, Ph.D., psychology professor, director of the University of Arizonas Grief, Loss and Social Stress Lab, and author of The Grieving Brain.
Ethics is just the examination of how we make decisions that affect other people and the world we live in. By deciding to give a crap, you are acknowledging a few basic but important truths: We are not the only people who matter. We rely on others for certain things, and they rely on us. The big and small choices we make fall on a spectrum from "Excellent" to "Extremely obnoxious and bad," and where they fall is (at least in part) up to us. The only possible advice is (1) Decide to care. (2) Understand that it's a lifelong job. (3) Accept that you make progress by being a little bit better today than you were yesterday. (4) Know for a fact that from time to time, even trying your best, you're going to fail in your quest to do the right thing. And that it's okay.
Michael Schur, creator of The Good Place, co-creator of Parks and Recreation, and author of How to Be Perfect: The Correct Answer to Every Moral Question, out now.
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14 Easy Ways to Extend and Enhance Your Life, Starting Now - Men's Health
The Steam Deck battery life guide: games tested and how to extend it – Rock Paper Shotgun
The Steam Decks battery life isnt one of its best qualities. While this weakness is outweighed by the pleasures of playing PC games in bed or on the bus, most such games will drain the Deck quickly, requiring a degree of foresight if you want to entertain yourself on a long trip away from mains power. At the same time, different games will drain at different speeds, with some allowing Valves handheld to last hours longer than others.
Ultimately, I think the only truly accurate way to measure and judge the Steam Decks battery life is to test a bunch of different games to see how long it lasts with each. So I have! Here youll find a list of games with how long they took to empty the Decks battery from full. Ill be coming back and adding more to the list as I test them, so you can see for yourself what uptimes to expect from your favourites.
Ive also thrown in some tips on how to extend the Steam Decks battery life, which is possible even when running the thirstiest AAA games. Also, if you want to know how long a certain game will last and it isnt yet on the list, let me know in the comments it doesnt have to be one of the Steam Deck Verified games, but as long as its compatible enough to run, I may well be able to test it and add it.
Valve say the Steam Deck should last between two and eight hours, but depending on the game as well as certain hardware settings on the Deck itself battery life can vary even more. The absolute most Ive wrung out is 9h 17m (in Super Meat Boy, with Airplane mode and minimum screen brightness), while the shortest Ive seen is a scant 1h 17m (Horizon Zero Dawn with everything running at max). For this list, Ive stuck with more normal usage conditions, like setting screen brightness to 50% but leaving Wi-Fi on; you can see the full test settings on the right.
For now this is a hodgepodge of some of the most popular games on Steam by player count, and a few that I happened to have installed already, but the plan is for it to grow. Like a beautiful tall sunflower, made of numbers. Ill therefore be adding games (both new and old) on a regular basis, so again, do shout if theres one in particular youd like to see.
As rapidly as most games guzzle charge, the Steam Deck is flexible enough to give you a few different options for making that battery juice go further. In fact, almost all of these can be found in one place: the Performance tab of the Quick Settings menu. To find this, press the Quick Settings button (the three-dottted one just below the right trackpad) and select the battery icon. Lowering brightness can also help theres a slider for this in Quick Settings too, accessible via the gear icon. Here's what you can try:
Lower the display brightness A classic battery life extension trick dating back as long as adjustable backlighting has existed. Dropping the screen brightness might leave you at the mercy of reflections, especially on the 64GB and 256GB Steam Deck models (which dont have the 512GB model's matte display finish), but it can definitely help net you a few more minutes of play. Be sure to turn of dynamic brightness while youre at it, to make sure you have full control.
Limit the frame rate The Deck has a universal frame rate limiter built right in, and lowering it from 60fps to 30fps will reduce system strain to grant a modest battery life boost. I slapped a 30fps cap on Forza Horizon 5 and got 2h 03m out of it, adding an extra 26 minutes (or a 27% improvement).
Manually set the TDP limit This requires a bit of trial and error, but can prevent the Steam Deck from using more power than it needs. While in game, open the Performance tab and turn on the performance overlay so you can see your current FPS. Then, toggle the TDP limiter, set the slider all the way to the right, then lower it one step at a time until your FPS starts to drop. Slide it back up one step, and the Decks APU wont draw more power than it needs to maintain that performance level.
Manually set the GPU clock speed Similarly to the TDP limiter, you can downclock the graphics processor until its only just fast enough to deliver the performance you need and no more. Again, youre best off doing this on a per-game basis, using the FPS counter as a guide, as some games need a faster GPU than others.
Disable wireless connectivity The Decks setting menu provides am easy toggle for Airplane mode, which disables Wi-Fi and Bluetooth and thus helps stretch out battery life a little. There are also individual toggles for Wi-Fi and Bluetooth in the same place, so you can for instance shut off Wi-Fi but keep using a pair of wireless headphones.
I also tried the Decks baked-in AMD FSR upscaling, on the grounds that rendering games at a lower resolution might reduce system load and therefore power usage. It didnt really help, though: Fallout 4 with FSR emptied the battery in 1h 51m, just three minutes more than without it. Stick with the five steps above.
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The Steam Deck battery life guide: games tested and how to extend it - Rock Paper Shotgun
Fungus being tested at state park in Weslaco to control invasive species of ants – KRGV
Estero Llano Grande State Park in Weslaco have been testing the use of a fungus to control an invasive species of ants attacking small animals.
The tawny crazy ants have been spreading in the Valley and the Gulf Coast. They're an invasive species from South America.
The ants have attacked small animals and even make colonies inside electric equipment, causing thousands of dollars in damage.
"There's lots of birds that when they nested, the eggs hatched, and the ants would just cover the newborn chicks," said Javier De Leon, superintendent of Estero Llano Grande State Park. "So, the newborn birds had no chance. So, we saw lots of nest failures, especially chachalacas that are born on the ground and run within minutes, just like chickens. We saw several baby chachalacas that didn't make it.
Deleon says the fungus all but eliminated the ants from the park, but warns they can also affect your home.
Look for light brown ants that don't burrow or dig like other ants.
Then, take a picture and contact the Texas A&M Agri-life Extension for help identifying them and advice on what to do.
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Fungus being tested at state park in Weslaco to control invasive species of ants - KRGV
Industry Inspection Overview of Black Cumin Seed Oil Machine Market 2022-29 | Earthoil Plantations, Life Extension, Nuverus, Omega Pharma FortBendNow…
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Marines will have to wait at least until 2025 for light amphibious warship – Marine Corps Times
Marine leaders have been pushing since for the first light amphibious warship to be procured by 2023.
But in the services recent combined budget request with the Navy, the Corps isnt expecting to get the ship for at least another two years. And the Corps only is likely to get four of them in inventory by 2027 if the current plan holds.
The light amphibious warship is the Corps answer to moving a lot of Marines in small teams from deep water to the close-to-shore littoral zones and even conducting beach landings.
Far cheaper than the larger amphibious ships that Marines usually take to combat, the light amphibious warship is expected to fill a gap between big-deck ships and small landing craft. Without it, Marines face serious obstacles in getting on land. Thats critical as the Corps has billed itself as the Navys ship-killing, adversary-harassing force.
Each light amphibious warship is expected to carry up to 75 Marines. The Corps wants to use a host of them to move its newest formation creation, the Marine littoral regiment, around the littoral battlespace.
Thats going to be hard when even by 2027 it will only have enough space aboard potentially four new vessels for fewer than three reduced-strength, unsupported infantry companies.
To meet Marine war planning expectations, theyll likely eventually need enough light amphibious warships to transport at least three Marine littoral regiments.
But the Marine Corps will have to wait at least until fiscal year 2025, according to the militarys proposed fiscal year 2023 budget released on Monday. The Navy expects to start funding builds of the light amphibious warship with one in 2025, another in 2026 and two in 2027.
Marine Corps Commandant Gen. David Berger said at the National Defense Industrial Associations annual Expeditionary Warfare Conference in February that the traditional amphib ships and the new light amphibious warship concept complement each other. They will work in tandem to bring Marines to the fight.
More details on budget specifics will be available in the coming weeks. But the Pentagons initial budget request gives glimpses as to what will happen with Marines and ships in the near- to mid-term.
At a briefing with media on Monday, Navy Rear Adm. John Gumbleton, deputy assistant secretary of the Navy for budget, said that both the Navy and Marine Corps were working to get the requirements tight for the light amphibious warship.
He pointed to funding in research and development rather than procurement in the near term.
While still in the design phase, the Marines are asking to build a 200- to 400-foot ship with a maximum draft of 12 feet. The ship must be able to carry between 3,000 and 4,000 tons and 75 Marines with a Navy crew of about 40 sailors.
That program saw $20 million in funding in fiscal 2021, $13 million in fiscal 2022 and hovers around $12 million for the pending 2023 budget.
Thats behind the timeline in the Corps goal of having a light amphibious warship funded by 2023 and deployable soon after.
The Navys $27.9 billion shipbuilding proposal expects to fund nine new ship builds. More than half of that money is taken up by incremental funding for the Ford-class aircraft carrier, the Columbia-class and the Virginia-class nuclear submarines.
Of what remains in the purse, a handful of Marine-focused priorities look to get funding, though not at quite at the level or pace Corps leadership has pushed for in recent years.
Two of those the America class amphibious assault ship-LHA 6 and the San Antonio class amphibious transport dock or LPD 17 Flight II are on deck for funding.
In existing construction or serve life extension, the Navy looks to pay for two landing craft air cushion and two ship-to-shore connectors in 2023, also key to Marine gear and troop movement in the littorals.
The Marines F-35C Joint Strike Fighter purchases dropped to nine for the 2023 budget, but would resume at 15 each year until fiscal 2027. The Corps purchased 16 in fiscal 2021 and 15 in fiscal 2022.
Purchases of the F-35B are consistent with 15 planned in the fiscal 2023 budget and 16 each year until 2026, with 17 in fiscal 2027. In the 2022 budget, Marines bought 17 of the B variant, having purchased 10 in fiscal 2021.
Both Navy and Marine Corps aviators are getting a new trainer, the Corps will see four such aircraft in this 2023 budget and 22 total over the next two years.
KC-130J buys are steady at five and another two planned for fiscal 2024. The Corps bought 11 over the previous two fiscal years.
Marine aviators are likely to see many more CH-53K King Stallion helicopters in the coming years.
The proposal lays out a plan to buy 10, with another 78 spread out over the next four years.
Research and development spending on the King Stallion continues, though lower than in years past. Current figures in the budget call for $220 million, down from $257 million in fiscal 2022.
It appears the Marines are done buying MV-22 Ospreys for the foreseeable future.
Two years ago, the Corps purchased three, and in 2022, it was given funding for nine. But no future purchases are planned within this budget through fiscal 2027.
Todd South has written about crime, courts, government and the military for multiple publications since 2004 and was named a 2014 Pulitzer finalist for a co-written project on witness intimidation. Todd is a Marine veteran of the Iraq War.
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Marines will have to wait at least until 2025 for light amphibious warship - Marine Corps Times
Doctor Shares 5 Surprising Things That Stress Does To Your Body – Hackensack Meridian Health
For those of us who work, commute, have relationships, care for families and try to pack too many responsibilities into each day, stress may be an ever-present, unwanted companion.
You experience stress when your body responds to an emotionally or physically challenging situation. Short-term stress isnt associated with health problems, but long-term or chronic stress is.
When your body recognizes that you are stressed, it releases hormones to help you get through the situation, but in the modern world, those hormones arent always helpful, says Eric C. Alcera, M.D., a behavioral health specialist at Hackensack Meridian Health. In the past, a burst of stress hormones like cortisol or adrenaline may have helped you run to safety when you were being chased by wild animals, but when youre sitting at your desk feeling stressed about a work project, the influx of stress hormones doesnt have the same effect.
Common health problems that are associated with chronic stress include:
Chronic stress may also impact your body in unexpected ways.
Adopting healthy habits may help you feel less stressed, which may make you less likely to experience stress-related health problems. Try to incorporate these lifestyle habits into your routine:
The material provided through HealthU is intended to be used as general information only and should not replace the advice of your physician. Always consult your physician for individual care.
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Doctor Shares 5 Surprising Things That Stress Does To Your Body - Hackensack Meridian Health
About the Advanced Age Management Medina Testosterone Replacement Therapy in Medina, OH – Digital Journal
Medina, OH: The safe and effective hormone therapy at Advanced Age Management targets people with various health issues, including weight gain, tiredness, declining sex drive, and depressed mood. For men over 35 years, these health problems could result from low testosterone levels and other hormonal issues. That is why the trt center is happy to work with all symptomatic patients. The wellness center for men is well-equipped to offer Hypothyroidism Therapy, Hormone Replacement Treatment, Erectile Dysfunction Treatment, and Low T Symptoms. Other treatments offered by Advanced Age Management are Testosterone Replacement Therapy and Growth Hormone Releasing and Medical Peptide Therapy.
For over 15 years, Advanced Age Management has served patients from varied backgrounds, including professional athletes. The advanced treatment facility for men is owned and managed by John Kocka M.D., a board-certified physician and age management specialist. Dr. Kocka is board-certified in Age Management from the American Academy of Anti Aging, Age Management Medical Group and physician-certified by the Cenegenics Medical Institute. He is a member of the International Hormone Society, International Society for the Study of the Aging Male and the American College of Sports Medicine. He is a trusted authority in testosterone replacement therapy.
Hormone Replacement Therapy (HRT) is a process of replenishing naturally produced hormones among men. The process usually happens when men age and may lead to increased pain and aches, insomnia, sleep disturbance, and slower metabolism, which often leads to increased body fat and other health complications. The pros of choosing Advanced Age Management include an opportunity to work with a leading doctor, access to comprehensive and tailored treatment solutions, and ongoing support from in-house physicians.
The HRT treatment for men plays a vital role in revitalizing sex drive, building muscle mass, and promoting the production of red blood cells. For men with low testosterone levels, the treatment can go a long way to promote vitality, health, and enhance the quality of life. Dr. Kocka begins treatment by creating a custom treatment solution. Treatments such as medina testosterone replacement therapy are supplemented by healthier habits, such as exercise, improved diet, and quality sleep.
Another critical treatment offered by Advanced Age Management is Vitamin B12 and other Amino Acid Treatments. The cost of treatment varies depending on the type of treatment and personalized medical treatment plans. Patient reviews posted on the website paint a picture of an advanced treatment facility that is highly recommended for its friendly and knowledgeable staff and excellent treatment facilities.
To get in touch with the treatment experts at Advanced Age Management, call 216.471.8220, or visit them at 1188 Medina Rd R18, Medina, OH, 44256. The clinic is keen to address health concerns and improve quality of life. They operate Monday to Friday at different hours, between 8:00 am to 5:30 pm.
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Company NameAdvanced Age ManagementContact NameJohn Kocka, M.D.Phone216.471.8220Address1188 Medina Rd R18CityMedinaStateOHPostal Code44256CountryUnited StatesWebsitehttps://www.lowtohio.com/
Half of Women Will Get False-Positive Mammogram Over 10 Years of Screening – HealthDay News
TUESDAY, March 29, 2022 (HealthDay News) -- Fully half of all women who have annual mammograms to screen for breast cancer will receive a false-positive test result over a decade of screening, according to a new study.
False-positive results call for further testing and eventually rule out cancer. False alarms can certainly increase anxiety.
"Women undergoing screening mammography should be aware that being recalled for additional imaging is common and try not to worry," said study author Diana Miglioretti, a professor and division chief of biostatistics at the University of California, Davis. "Most of the time, the additional imaging shows that everything is normal."
For the study, Miglioretti and her colleagues analyzed data from close to 3 million screening mammograms for more than 903,000 women between 40 and 79 years of age. The participants underwent breast cancer screening between 2005 and 2018 at 126 radiology centers.
The study found the risk of false-positive results is lower in women who are screened every other year.
Yearly screening with newer 3D technology called digital breast tomosynthesis or 3D mammography modestly decreased the odds of a false positive when compared with the standard digital 2D mammography.
Of women who received a false-positive result after an annual 3D mammogram, 17% needed additional imaging, and 11% needed a biopsy to rule out cancer. These numbers were just slightly higher among women screened with digital 2D mammograms.
Older women and women who don't have dense breasts were less likely to get a false-positive result, the study showed.
There's been an ongoing debate within the medical community about how often women should undergo breast cancer screening.
The U.S. Preventive Services Task Force recommends women who are at average risk for breast cancer get their first mammogram at age 50, and then every two years until age 74.
Meanwhile, the American Cancer Society says 40- to 44-year-old women should consider annual mammograms. They are recommended for women between 45 and 54 years of age.
"Screening every two years has been found to be effective for most women in terms of detecting cancer early while reducing the harms of screening such as false positives," Miglioretti said.
Still, she said, guidelines aren't written in stone.
"Some women at higher risk of advanced cancer despite screening might choose to screen annually, for example, postmenopausal women who are obese or taking hormone replacement therapy," Miglioretti said. "If women are unsure, they should talk with their clinicians about the tradeoffs of annual versus biennial screening."
The study was published March 25 in JAMA Network Open.
Being called back after a screening mammogram or ultrasound for additional images or a biopsy should be considered routine, said Dr. Laurie Margolies, chief of breast imaging at Mount Sinai Health System in New York City. She was not part of the study, but reviewed the findings.
"It is not a cause of alarm as most of the time we can clear people with additional images," Margolies said.
Getting a mammogram every two years instead of yearly is a "major mistake," she warned. The new study doesn't look at cancers found by yearly screens compared with screens done every two years.
"People who skip a mammogram often have larger cancers and are really sorry that they didnt come the previous year when the cancer would have been smaller and easier to treat," Margolies said.
Mammograms aren't perfect, but they are getting better, said Dr. Marisa Weiss, founder and chief medical officer of Breastcancer.org and Breasthealth.org in Ardmore, Pa.
"We still need better methods of early detection that both reduce the risk of a false positive [false alarm] and lower the risk of a false negative [missing a cancer] for all women, especially young women who are more likely to have dense breasts, an inherited high-risk predisposition, and more at stake: young children, growing careers, more years of life at risk," said Weiss, who has no ties to the research.
More information
Breastcancer.org has more about breast cancer screening.
SOURCES: Diana Miglioretti, PhD, professor, division chief of biostatistics, University of California, Davis; Laurie Margolies, MD, chief, breast imaging, Mount Sinai Health System, New York City; Marisa Weiss, MD, founder/chief medical officer, Breastcancer.org and Breasthealth.org, Ardmore, Pa.; JAMA Network Open, March 25, 2022
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Half of Women Will Get False-Positive Mammogram Over 10 Years of Screening - HealthDay News
What Is Medical Gaslighting and How Can You Elevate Health Care – The New York Times
Today thanks in large part to a law passed in 1993 that mandated that women and minorities be included in medical research funded by the National Institutes of Health women are more systematically included in studies, yet there are still huge knowledge gaps.
For instance, women with heart disease often have different symptoms from men with heart disease, yet doctors are much more familiar with the male symptoms, said Dr. Jennifer Mieres, a cardiologist with Northwell Health in New York. When women show up with symptoms that dont fit into the algorithm were taught in medical school, she said, they get gaslit and ignored.
By the time Michelle Cho, 32, was diagnosed with systemic lupus erythematosus, a disease in which the body slowly attacks its own tissues, she had developed kidney failure, a heart murmur and pneumonia yet the first doctor she went to diagnosed her with allergies, she said, and the second doctor thought she was pregnant.
I left each time feeling disappointed, sad and uneasy, because I knew they had not solved my problem or helped me in any way, and it had been yet another wasted day, said Ms. Cho, a New York City-based medical student. It felt like they were saying, Its all in my head.
When Raimey Gallant, a 42-year-old writer who lives in Winnipeg, began dropping weight, losing her hair and breaking out in a full-body rash in her 20s, she said her male doctor told her she was young, healthy and just lazy, when in fact, later that year she was diagnosed with Graves Disease, an autoimmune disorder in which the body produces too much thyroid hormone.
She also struggled for 20 years with disabling period pain before finally getting diagnosed last year with endometriosis, an inflammatory disease characterized by the presence of endometrial-like tissue outside the uterus. Ill never get back the pieces of life Ive lost to medical neglect, she said.
Its hard to know how to begin to address these systemic problems, experts said, but scientists argue that at the very least, there needs to be more research on womens health conditions.
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What Is Medical Gaslighting and How Can You Elevate Health Care - The New York Times
What You Need to Know When You’re Working During Fertility Treatment – Healthline
Anyone whos ever tried to conceive knows that there are countless highs and lows during the process. To say you might be a little stressed during this period is a bit of an understatement.
While trying to conceive (TTC) can be an emotional rollercoaster on its own, the experience can become even more emotionally fraught for people relying on fertility treatments, such as in vitro fertilization (IVF).
How do you go on with everyday life while undergoing treatments? In particular, many people going through fertility treatment still work full time. Understanding how to manage that stress and finding positive outlets for encouragement and support can help you manage.
Experiencing fertility concerns can be an isolating experience, but the reality is that theyre incredibly common. According to the American Society for Reproductive Medicine (ASRM), roughly 10 to 15 percent of American couples experience infertility.
Fertility concerns can impact the sperm-giving partner, too. Male and female infertility each contribute to one-third of infertility cases, according to ASRM. The remaining one-third is a combination of both male and female infertility.
If youre going to continue working during fertility treatment, certain factors can make the experience more complicated. Insurance coverage can vary widely by company, and family leave policies can depend on both your employer and the state you live in.
Before you can begin figuring out how to work through fertility treatments, you need to determine your rights, and what benefits if any you have access to.
Depending on your employer and how long youve worked with them, you might qualify for FMLA. While FMLA guarantees only unpaid time off, you could get up to 12 weeks of unpaid leave every year. You could use this leave toward parental leave.
By strict definition, FMLA isnt designed to cover infertility treatments. However, if your healthcare professional can affirm that your fertility treatments are medically necessary for you to become pregnant, you may potentially apply FMLA leave toward treatments or even medically required bed rest during pregnancy.
Many companies that arent governed by FMLA do offer generous parental leave and health policies including covered health expenses. When in doubt, speak with your companys human resources or benefits manager to fully understand what leave if any you can use. They can also tell you whether your insurance will cover any treatments.
In theory, your medical situation is no ones business, and you have a right to privacy. But depending on the type of fertility treatments youre using, it might be unrealistic to keep this process to yourself.
For example, IVF is managed in cycles that usually coincide with your menstrual cycle. This means that a full IVF cycle can last several weeks, and many couples require more than one cycle to achieve success. Youll need to factor in several appointments, including procedures like egg retrieval and embryo transfer.
Beyond that, keep in mind that some treatments require taking fertility medications. These can create unexpected reactions both physically and emotionally. Many fertility specialists recommend taking 1 or 2 days off from work for the egg retrieval procedure, and some doctors recommend taking a few days off after the embryo transfer as well.
Only you know how agreeable your workplace will be to you taking time off periodically throughout the month to manage fertility treatments. At a minimum, be prepared to talk with direct managers or your human resources point of contact because youll need their approval to take time off or coordinate benefits.
But youll also need to consider other factors.
If youre thinking of taking a hybrid work approach, where youre primarily in the office but working remotely during critical points in an IVF cycle, other people might also need to know why youre out of the office. Anyone considered critical to ensuring that your job runs smoothly should realistically be kept in the loop.
Additionally, if you have close work friends who you trust and believe will provide much-needed support, you might want to tell them. We cant stress enough that fertility treatments can be draining both emotionally and physically.
ASRMs Mental Health Professional Group (MHPG) agrees about this psychological impact. So, having a solid support system in all aspects of your life can be very helpful.
Remember that you control the narrative. You can provide general information without sharing all the details. Fertility concerns are a sensitive topic that not everyone is comfortable talking about.
Plus, theres the added reality that while legal protections against workplace gender discrimination exist, some people have reported feeling like their work ethic or capabilities were questioned once disclosing that they were undergoing fertility treatments.
So, if youre only comfortable saying you have to undergo medically necessary procedures, leave it at that and dont feel pressured to share more. If necessary, get documented support from your healthcare professional.
The TTC process is a rigorous one, but even more so when youre also battling infertility. While its important to cover your bases professionally, you also need to be kind to yourself as you navigate treatment.
Between the physical side effects of fertility drugs and the shifting emotions, you might not be up to maintaining your usual schedule. This is especially true if youre juggling a full-time job, multiple fertility appointments and procedures, and remembering to take medications.
Dont feel pressured to maintain your pre-fertility treatment schedule if its going to leave you frazzled and exhausted. Taking care of yourself is priority number one!
No matter how you conceive, anyone whos ever attempted to get pregnant will tell you that having a sympathetic and supportive network can help make the experience more manageable.
You may choose to round up friends and family in your social network who can help you get through this time. Its also good to connect with fertility treatment support groups so you can talk with someone who knows what youre going through.
Youre going through a rough period, so feel free to pamper yourself just a bit more. Whether self-care looks like booking a massage or having a reality show marathon, you deserve to spend a few moments not being preoccupied with your fertility.
If youre undergoing fertility treatments, youre already taking one of the most proactive steps possible to achieve your ultimate goal of getting pregnant.
It can be tempting to spend time online looking up details about fertility treatment success rates, plus what early pregnancy symptoms to expect and how to spot them. But this can encourage rumination and spiraling thoughts, which can make an already stressful situation feel worse.
If you have questions about fertility or fertility treatments, talk with your healthcare professional about them instead. After all, theyre the pro!
Dont underestimate the importance of spending time talking with someone whos not in your social circle and who can serve as a neutral sounding board. Again, fertility concerns and, by extension, fertility treatments can throw you for many emotional loops.
Countless studies have shown that living with infertility can have a serious and long-term impact on your mental health, according to a 2008 research review. Having a safe space to talk through whats bothering you, as well as learning other effective coping methods, is important.
Not everyone can take time off from work to accommodate fertility treatments. If youre able, work with your companys human resources or benefits director to determine what leave or medical coverage can be applied to your treatments.
While you may need to tell key stakeholders at work whats going on, dont feel pressured to share every little detail or tell every single person. Its important to take care of yourself and make sure you have a strong support system around you during treatment.
Excerpt from:
What You Need to Know When You're Working During Fertility Treatment - Healthline
Introduction to Ovarian Cancer – Rising Kashmir
Ovarian cancer is a growth of cells that forms in the ovaries.The cells multiply quickly and can invade and destroy healthy body tissue.The female reproductive system contains two ovaries, one on each side of the uterus.The ovaries each about the size of an Almond produce eggs(ova) as well as the hormones estrogen and progesterone.
Signs & symptoms
When ovarian cancer first develops,it might not cause any noticeable symptoms.When ovarian cancer symptoms happen,they're usually attributed to other,more common conditions.
Signs and symptoms of ovarian cancer may include:
a.Abdominal bloating or swelling.
b.Quickly feeling full when eating.
c.Weight loss.
d.Discomfort in the pelvic area.
e.Fatigue.
f.Back pain.
g.Changes in bowel habits,such as constipation.
h.A frequent need to urinate.
Causes of Ovarian Cancer
It's not clear what causes ovarian cancer, though doctors have identified things that can increase the risk of the disease.
Doctors know that ovarian cancer begins when cells in or near the ovaries develop changes(mutations) in their DNA.A cell's DNA contains the instructions that tell the cell what to do.The changes tell the cells to grow and multiply quickly,creating a mass (tumor)of cancer cells.The cancer cells continue living when healthy cells would die.They can invade nearby tissues and break off from an initial tumor to spread (metastasize) to other parts of the body.
Types of ovarian cancer
The type of cell where the cancer begins determines the type of ovarian cancer you have and helps your doctor determine which treatments are best for you.Ovarian cancer types include:
a.Epithelial ovarian cancer:This type is the most common.It includes several subtypes, including serous carcinoma and mucinous carcinoma.
b.Stromal tumors:These rare tumors are usually diagnosed at an earlier stage than other ovarian cancers.
c.Germ cell tumors:These rare ovarian cancers tend to occur at a younger age.
Risk factors
Factors that can increase your risk of ovarian cancer include:
a.Older age:The risk of ovarian cancer increases as you age. It's most often diagnosed in older adults.
b.Inherited gene changes:A small percentage of ovarian cancers are caused by genes changes you inherit from your parents.The genes that increase the risk of ovarian cancer include BRCA1 and BRCA2. These genes also increase the risk of breast cancer.Several other gene changes are known to increase the risk of ovarian cancer, including gene changes associated with Lynch syndrome and the genes BRIP1, RAD51C and RAD51D.
c.Family history of ovarian cancer:If you have blood relatives who have been diagnosed with ovarian cancer,you may have an increased risk of the disease.
Being overweight or obese.Being overweight or obese increases the risk of ovarian cancer.
d.Postmenopausal hormone replacement therapy:Taking hormone replacement therapy to control menopause signs and symptoms may increase the risk of ovarian cancer.
e.Endometriosis:Endometriosis is an often painful disorder in which tissue similar to the tissue that lines the inside of your uterus grows outside your uterus.
f.Age: Age when menstruation started and ended.Beginning menstruation at an early age or starting menopause at a later age, or both,may increase the risk of ovarian cancer.
g.Never having been pregnant:If you've never been pregnant, you may have an increased risk of ovarian cancer.
Prevention
There's no sure way to prevent ovarian cancer.But there may be ways to reduce your risk:
a.Consider taking birth control pills:Ask your Physician whether birth control pills (oral contraceptives)may be right for you. Taking birth control pills reduces the risk of ovarian cancer.But these medications do have risks,so discuss whether the benefits outweigh those risks based on your situation.
b.Discuss your risk factors with your doctor:If you have a family history of breast and ovarian cancers, bring this up with your doctor.Your doctor can determine what this may mean for your own risk of cancer. You may be referred to a genetic counselor who can help you decide whether genetic testing may be right for you.If you're found to have a gene change that increases your risk of ovarian cancer,you may consider surgery to remove your ovaries to prevent cancer.
Diagnosis
Tests and procedures used to diagnose ovarian cancer include:
a.Pelvic exam:During a pelvic exam,your physician inserts gloved fingers into your vagina and simultaneously presses a hand on your abdomen in order to feel(palpate) your pelvic organs.The doctor also visually examines your external genitalia,vagina and cervix.
b.Imaging tests:Tests,such as ultrasound or CT scans of your abdomen and pelvis, may help determine the size,shape and structure of your ovaries.
c.Blood tests:Blood tests might include organ function tests that can help determine your overall health.
Your doctor might also test your blood for tumor markers that indicate ovarian cancer. For example, a cancer antigen(CA) 125 test can detect a protein that's often found on the surface of ovarian cancer cells.These tests can't tell your doctor whether you have cancer,but they may provide clues about your diagnosis and prognosis.
d.Surgery:Sometimes your doctor can't be certain of your diagnosis until you undergo surgery to remove an ovary and have it tested for signs of cancer.
e.Genetic testing:Your doctor may recommend testing a sample of your blood to look for gene changes that increase the risk of ovarian cancer.Knowing you have an inherited change in your DNA helps your doctor make decisions about your treatment plan.You may wish to share the information with your blood relatives,such as your siblings and your children,since they also may have a risk of having those same gene changes.Once it's confirmed that you have ovarian cancer,your doctor will use information from your tests and procedures to assign your cancer a stage. The stages of ovarian cancer range from 1 to 4, which are often indicated with Roman numerals I to IV.The lowest stage indicates that the cancer is confined to the ovaries. By stage 4,the cancer has spread to distant areas of the body.
Treatment
Treatment of ovarian cancer usually involves a combination of surgery and chemotherapy.Other treatments may be used in certain situations.
a. Surgery to remove one ovary:For early-stage cancer that hasn't spread beyond one ovary, surgery may involve removing the affected ovary and its fallopian tube.This procedure may preserve your ability to have children.
b. Surgery to remove both ovaries:If cancer is present in both your ovaries,but there are no signs of additional cancer,your surgeon may remove both ovaries and both fallopian tubes.This procedure leaves your uterus intact,so you may still be able to become pregnant using your own frozen embryos or eggs or with eggs from a donor.
c.Surgery to remove both ovaries and the uterus:If your cancer is more extensive or if you don't wish to preserve your ability to have children,your surgeon will remove the ovaries,the fallopian tubes,the uterus, nearby lymph nodes and a fold of fatty abdominal tissue(Omentum).
d. Surgery for advanced cancer:If your cancer is advanced,your doctor may recommend surgery to remove as much of the cancer as possible.Sometimes chemotherapy is given before or after surgery in this situation.
e.Chemotherapy: Chemotherapy is a drug treatment that uses chemicals to kill fast-growing cells in the body,including cancer cells.Chemotherapy drugs can be injected into a vein or taken by mouth.Chemotherapy is often used after surgery to kill any cancer cells that might remain.It can also be used before surgery.In certain situations, chemotherapy drugs may be heated and infused into the abdomen during surgery (Hyperthermic Intraperitoneal Chemotherapy).The drugs are left in place for a certain amount of time before they're drained.Then the operation is completed.
f.Targeted therapy: Targeted drug treatments focus on specific weaknesses present within cancer cells. By attacking these weaknesses,targeted drug treatments can cause cancer cells to die.
If you're considering targeted therapy for ovarian cancer,your doctor may test your cancer cells to determine which targeted therapy is most likely to have an effect on your cancer.
g.Hormone therapy: Hormone therapy uses drugs to block the effects of the hormone estrogen on ovarian cancer cells.Some ovarian cancer cells use estrogen to help them grow,so blocking estrogen may help control the cancer.
Hormone therapy might be a treatment option for some types of slow-growing ovarian cancers.It may also be an option if the cancer comes back after initial treatments.
h.Immunotherapy: Immunotherapy uses the immune system to fight cancer.The body's disease-fighting immune system may not attack cancer cells because they produce proteins that help them hide from the immune system cells. Immunotherapy works by interfering with that process.Immunotherapy might be an option for treating ovarian cancer in certain situations.
i.Supportive(Palliative)care: Palliative care is specialized medical care that focuses on providing relief from pain and other symptoms of a serious illness. Palliative care specialists work with you, your family and your other doctors to provide an extra layer of support that complements your ongoing care.Palliative care can be used while undergoing other aggressive treatments,such as surgery and chemotherapy.When palliative care is used along with all of the other appropriate treatments, people with cancer may feel better and live longer.Palliative care is provided by a team of doctors,nurses and other specially trained professionals. Palliative care teams aim to improve the quality of life for people with cancer and their families.This form of care is offered alongside curative or other treatments you may be receiving.
Coping and support
A diagnosis of ovarian cancer can be overwhelming.In time you'll find ways to cope with your feelings,but in the meantime,you might find it helpful to:
a.Find someone to talk with:You may feel comfortable discussing your feelings with a friend or family member, or you might prefer meeting with a formal support group. Support groups for the families of people with cancer also are available.
b.Let people help:Cancer treatments can be exhausting.Let people know what would be most useful for you.
c.Set reasonable goals:Having goals helps you feel in control and can give you a sense of purpose.But choose goals that you can reach.
d.Take time for yourself:Eating well, relaxing and getting enough rest can help combat the stress and fatigue of cancer.
e.Preparing for your appointment:Start by making an appointment with your family Physician or gynecologist if you have any signs or symptoms that worry you.If your primary care Physician suspects that you have ovarian cancer,you may be referred to a specialist in female reproductive cancers(Gynecological Oncologist).A gynecological oncologist is an obstetrician-gynecologist(OB-GYN)who has additional training in the diagnosis and treatment of ovarian cancer and other gynecological cancers.
f.What you can do: Be aware of any pre-appointment restrictions,such as not eating solid food on the day before your appointment.
g.Write down your symptoms,including any that may seem unrelated to the reason why you scheduled the appointment.
h.Write down your key medical information, including other conditions.
i.Write down key personal information, including any major changes or stressors in your life.
j.Make a list of all your medications,vitamins or supplements.
k.Ask a relative or friend to accompany you, to help you remember what the doctor says.
l.Write down questions to ask your doctor:
l What's the most likely cause of my symptoms?
l What kinds of tests do I need?
l What treatments are available,and what side effects can I expect?
l What is the prognosis?
l If I still want to have children,what options are available to me?
l I have other health conditions.How can I best manage them together?
l In addition to the questions that you've prepared to ask your doctor,don't hesitate to ask other questions that occur to you.
m.What to expect from your doctor:Your doctor is likely to ask you a number of questions.Being ready to answer them may make time to go over points you want to spend more time on.You may be asked:
l When did you first begin experiencing symptoms,and how severe are they?
l Have your symptoms been continuous or occasional?
l What,if anything,seems to improve or worsen your symptoms?
l Do you have any relatives with ovarian or breast cancer?
l Are there other cancers in your family history?
Original post:
Introduction to Ovarian Cancer - Rising Kashmir
Dr. George on Efforts to Address Unmet Needs in HER2-Low Breast Cancer – OncLive
Mridula George, MD, discusses efforts to address unmet needs in HER2-low breast cancer.
Mridula George, MD, medical oncologist, Stacy Goldstein Breast Cancer Center, Rutgers Cancer Institute of New Jersey, assistant professor of medicine, Rutgers Robert Wood Johnson Medical School, discusses efforts to address unmet needs in HER2-low breast cancer.
The phase 3 DESTINY-Breast04 trial (NCT03734029) investigated fam-trastuzumab deruxtecan-nxki (Enhertu) vs. physicians choice of chemotherapy in patients with unresectable or metastatic HER2-low breast cancer. This study was pivotal because there is currently no treatment for this subgroup of patients, George says.
DESTINY-Breast04 met its primary end point of progression free survival, plus the secondary end point of overall survival in the subgroup of patients with hormone receptorpositive disease, George explains.
Future research could explore potential combinations withtrastuzumab deruxtecan, such as CDK4/6 inhibitors, George continues. The HER2-low space will generate more clinical trials to better understand treatment options for this subtype of breast cancer, George concludes.
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Dr. George on Efforts to Address Unmet Needs in HER2-Low Breast Cancer - OncLive
Iowa nurses sanctioned for sex with patients, meth use and other violations – Iowa Capital Dispatch
The Iowa Board of Nursing has suspended the license of a nurse who allegedly had sex with a former psychiatric patient.
At its January meeting, the board voted to suspend the license of Shawn Sandersfeld of Muscatine indefinitely and ordered a mental-health and chemical-dependency evaluation.
Once that evaluation is completed, Sandersfeld must submit to any treatment that is recommended and, after showing proof of 12 months sobriety, may resume practice while serving a 12-month period of probation. Sandersfeld must also complete a three-day course on professional boundaries and ethics and submit to case-manager evaluations pertaining to competency and the ability to interact professionally with co-workers and patients.
The sanctions are tied to allegations by the board Sandersfeld was working as a psychiatric mental health nurse at an unspecified hospital in 2019 and provided nursing services to a particular patient who was discharged in July 2019.
According to the board, from August 2019 through June 2021, the patient lived at Sandersfelds home and the two engaged in a sexual relationship during that time.
According to the Iowa Board of Nursing, these other nurses have recently faced sanctions from the board:
Patrick Jones, Waterloo Jones agreed to immediately relinquish all rights to practice nursing in the state of Iowa and surrendered his license. He can apply for reinstatement in 12 months. According to the board, Jones was employed at a care facility, unspecified by the board, from September 2019 until July 2021.
At some point during his employment, the board alleged, Jones sent electronic communication to staff that created an uncomfortable work environment. According to the board, Jones communicated conversations that were sexual in nature with a patient and he engaged in sexual actions with a patient.
James Dickerson, Neola The board ordered Dickerson to immediately stop providing any treatment to patients with a complex mental health diagnosis until he received certification as a psychiatric nurse practitioner. The board also fined Dickerson $1,000 and ordered him to undergo five hours of consultation with a nurse practitioner. The settlement stemmed from charges that Taylor exceeded his scope of practice and dispensed drugs to individuals whose care was not within his specialized, licensed area of practice.
Miranda Figueroa, Omaha Figueroa agreed to immediately relinquish all rights to practice nursing in the state of Iowa and surrendered her license. She can apply for reinstatement in 12 months. Last October, the board charged her with an inability to safely practice nursing as a result of a physical or mental condition. At that time, the board indicated it had sought provider approval for Figueroa to safely practice nursing and that no provider had given that approval.
Kristine Wikner, McGregor Wikner agreed to undergo 10 hours of educational instruction on nursing documentation. In October, the board alleged she was working at a nursing home in 2020 when a family member was admitted to the facility. Although she was instructed not to access her family members medical records, she allegedly went into her relatives medical chart and changed some of the information entered there by another worker.
Nathan Tucker, Sioux City Tucker agreed to undergo 60 hours of educational instruction on critical thinking and nursing procedures. The board alleged that in October 2020, while working at a hospital emergency department, Tucker administered intravenous medication to patients on three occasions without a physicians order, failed to assess the IV sites, and failed to provide accurate information to a physician.
Terry Seitz, Williamsburg Seitz agreed to immediately relinquish all rights to practice nursing in the state of Iowa and surrendered her license. She can apply for reinstatement in 12 months. In September 2020, she was allegedly working at an unspecified facility when she had to be transported by emergency services to a hospital where she tested positive for amphetamines, marijuana and non-prescription opioids.
Mona Taylor, Rock Island, Ill. Taylor agreed to immediately relinquish all rights to practice nursing in the state of Iowa and she surrendered her license. She can apply for reinstatement in 12 months. The factual circumstances that triggered the action have yet to be made public. The board states that it filed a statement of charges against Taylor in October 2021, but that statement of charges has yet to be published by the board.
Kori March, Sioux City March agreed to undergo 60 hours of educational instruction pertaining to professional ethics and what the board called nurses legal advisor. Last fall, the board alleged that while working at an unspecified long-term care facility between 2018 and 2021, she performed intravenous therapy functions without having the IV-therapy certification required of licensed practical nurses.
Jennifer Mayberry, Waukee Mayberry agreed to have her license placed on probation for 18 months, during which time she must abstain from the use of alcohol and illicit drugs, submit to case-manager evaluations and chemical screening, and undergo mental health counseling. Last summer, the board alleged that during a pre-employment health screening in 2021, Mayberry tested positive for amphetamine and methamphetamine.
Derrick Miller, West Branch Miller agreed to have his license placed on probation for 12 months and to undergo six hours of educational instruction on medication safety. Last fall, the board alleged that in February 2021, while working at an unspecified nursing home, Miller lost the keys to the homes medication cart, left the unlocked cart unattended, and then left medication at a residents bedside without a doctors order to do so.
Eleven months earlier, Miller allegedly gave oxycodone to a resident who had not complained of pain and did not request the medication. In 2014, Millers license was indefinitely suspended pending completion of board-ordered treatment and verification of 12 continuous months of sobriety, followed by 12 months of license probation. The 2014 sanctions stemmed from charges of misappropriation of medications and being involved in the unauthorized manufacture or use of a controlled substance.
Ronda Eick, Waterloo The board issued Eick a warning and ordered her to undergo 34 hours of educational instruction on COVID-19 and medical documentation. Last fall, the board alleged that while Eick was working at an assisted living center in 2021, she received a text message from a co-worker who stated that he or she had COVID-19. Eick did not notify human resources, the facilitys clinical coordinator or the staffs health nurse of that information.
A few days earlier, two residents of the center had tested for COVID-19, with one showing a positive result and the other showing an inconclusive result. According to the board, Eick falsely reported that one of the two residents had tested negative for COVID-19. In 2008, the board ordered Eick to complete 15 hours of educational instruction related to ethics. That sanction stemmed from her pleading guilty to a criminal charge of theft tied to allegations that she stole money collected by colleagues for the benefit of a co-worker.
McKinsey Schurr, LeClaire The board issued Schurr a warning for excessive use of alcohol after it allegedly received information that Schurr had an alcohol-use disorder. The board charged Schurr with excessive use of alcohol that may impair a licensed nurses ability to practice.
Rhonda Adkins, Grinnell Adkins agreed to under 30 hours of educational instruction on professional ethics. Last fall, the board alleged Adkins was employed as a home care nurse in 2021 when she falsified patient records and employee timecards to indicate she was providing care for a patient on dates when she did not actually work.
Jennifer Evins, Rock Island, Ill. Evins agreed to immediately relinquish all rights to practice nursing in the state of Iowa and surrendered her license. She can apply for reinstatement in 12 months. Last fall, the board alleged that in 2020, Evins was convicted of a crime related to the profession of nursing and the theft of patient medications.
As a result of the criminal conviction, Evins license was placed on probation in October 2020 and she was barred from using alcohol while on probation. In June 2021, she allegedly tested positive for alcohol use and later admitted she had been drinking.
Amanda Bendon, Dubuque Bendon agreed to undergo up to 10 hours of educational instruction on ethics and legal liability. The board had alleged that Bendonwas working at an unspecified medical clinic in 2020 when she removed a vial of Pentacel from the clinic, took it home and administered it to her child without a prescription and without permission from the clinic. Pentacel is used as a vaccine for immunization against diphtheria, tetanus and other conditions.
Jennifer Mastin, Walnut Mastin agreed to undergo up to 10 hours of educational instruction on ethics and legal liability and have her license placed on 12 months probation. The board had alleged that on more than one occasion while working at an unspecified care center, Mastin disposed of medication without the required witness; removed two narcotics from the inventory and administered only one dose; and failed to document the administration of narcotics to residents.
Tricia Venzke, Ames Venzke agreed to undergo 30 hours of educational instruction on managing difficult patients. The board had alleged that in 2021, while dealing with a combative hospital patient, Venzke reacted physically inappropriately to the patient.
Miranda Depyer, Graettinger Depyer agreed to undergo seven hours of educational instruction on professional accountability and critical thinking skills. The board had alleged that in April of last year, Depyer responded to an ambulance call for a woman in labor. While en route to a hospital, Depyer allegedly gave the woman a dose of Pitocin a natural hormone sometimes used to induce labor without a physicians order.
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Iowa nurses sanctioned for sex with patients, meth use and other violations - Iowa Capital Dispatch