Archive for July, 2020
How to identify and treat strange things that might be happening on your skin – Las Vegas Sun
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By C. Moon Reed (contact)
Saturday, July 25, 2020 | 2 a.m.
Skin. Its our bodys biggest organ. Our protective envelope exists to keep the outside world out and the inside in. And yet its easy to ignore, up until the moment something goes wrong. Whats that weird rash? Who knows? Sure, you can use a phone filter to make your skin look great, but its better to address the problem and enjoy clear skin.
Weve rounded up info on some of the most common skin conditions that affect mankind, but this shouldnt replace professional medical advice. If you think something looks wrong, please consult a doctor.
Prevention is the best cure, so follow these simple steps to keep your skin healthy and happy.
Wash your hands.
Practice good hygiene.
Manage stress.
Eat a healthy diet.
Sleep enough.
Moisturize to prevent dry, cracked skin.
Dont share personal items like towels, razors and nail clippers.
Avoid touching your face.
Dont pick at, shave over, pop or scratch irritated skin, no matter how tempting.
Dont touch other peoples skin lesions.
Cover skin wounds, warts, etc. to speed healing and prevent cross-contamination.
Wear flip-flops around swimming pools and public showers.
Protect yourself from sun damage.
ACNE
Its the bane of pubescence. But pimples can linger beyond the teenage years.
Who: Everybody. Its the most common skin issue in the United States.
Cause: Pores clogged by dead skin cells get infected by a common skin bacteria, P. acnes. Risk factors include genetics, hormones, being female.
Symptoms: From cysts to blackheads to pustules and whiteheads, these blemishes can plague the face, chest, back, arms and buttocksand lead to scarring and dark spots.
Contagious? No.
Treatment: Start with over-the-counter topical treatments and see a dermatologist for prescription treatment if your acne is severe or not responding to other efforts. Do not pop pimples; it can make them worse and cause scarring.
CONTACT DERMATITIS
A general term for the type of rash one gets when skin comes into contact with an irritant.
Who: Anybody, but allergies are a risk factor.
Cause: Seasonal allergies; allergies to cheap jewelry (generally with nickel), cosmetics, detergents, medications, tattoo pigments, etc.
Symptoms: Itching, redness, swelling.
Contagious? No.
Treatment: Remove the irritant, and avoid future contact.
DANDRUFF
A type of dermatitis (seborrheic) that mainly affects the scalp.
Who: Mostly people with genetic predispositions, immune or nutrition issues.
Cause: Genetics, environmental factors, dry skin, stress.
Symptoms:Itching, flaking, discoloration of the skin.
Contagious? No.
Treatment: Medicated dandruff shampoo; shampoo daily; eat a healthy diet; get some sun; apply tea tree oil. Seek prescription treatments if the above doesnt help.
ECZEMA
Think of this chronic skin condition like asthma of the skin. Skin can be normal, and then suffer from outbreaks, like an allergic reaction.
Who: Anybody, but those with asthma or allergies are at higher risk.
Cause: Genetics, skin irritation or damage, immune issues.
Symptoms: Dryness, redness, itching, cracking, bleeding, infection.
Contagious? No.
Treatment: Hydrocortisone, antihistamines, steroid creams, laser therapy, immunosuppressants.
KERATOSIS PILARIS
An inherited skin condition that can make the upper arms, thighs, buttocks and/or cheeks appear to have goosebumps or whiteheads.
Cause: Genetics, worsened by dry environments.
Who: More common in children and young adults and generally resolves itself with age.
Symptoms: Painless, but can cause bumps and coarse skin.
Contagious? No.
Treatment: Exfoliate and moisturize; salicylic acid, topical retinoids.
MOLES
Mostly everybody has a mole somewhere or other. Generally, these pigmented skin growths are harmless, but some can be risk factors for melanoma (skin cancer).
Who: Almost everybody.
Cause: Irregular or clumpy growth of pigmented skin cells.
Symptoms: Beware of moles that are asymmetrical, oddly shaped, multicolored, larger than a pencil eraser and/or quickly changing, as these can be signs of melanoma.
Contagious? No.
Treatment: If your moles seem irregular, see a doctor immediately. Most moles dont require treatment, but if needed, they can be surgically removed by a dermatologist. In general, its a good idea to monitor your moles over time, just to make sure they dont turn against you.
MOLLUSCUM CONTAGIOSUM
This skin disease is caused by a poxvirus that lives in the upper layer of the skin.
Who: Anybody, but people with compromised immune systems are at higher risk.
Cause: Viral infection spread via physical contact (either skin-to-skin or via shared objects, such as towels or toys).
Symptoms: Itching, redness, small bumps with a pearly appearance.
Contagious? Yes, but your body can completely clear the infection.
Treatment: The disease typically clears on its own in six months to four years. A medical professional can help remove the lesions; do not attempt on your own.
PSORIASIS
Skin generally takes weeks to grow, but with this skin condition, it grows at hyperspeed, causing significant irritation.
Who: Genetics combined with triggering events such as stress, weather and/or medication.
Cause: An overactive immune system, generally.
Symptoms: Most people develop plaque psoriasis, which consists of scaly, raised patches that can look silver. They are very itchy, but scratching makes it worse. Other types of psoriasis include rashes and irritation on different parts of the body.
Contagious? No.
Treatment: Prescription medication, including lotions, pills and injections.
ROSACEA
Santa Claus is famous for his rosy cheeks. But what you took for Christmas cheer is most likely the skin condition rosacea.
Who: Older people, mostly women, with fair skin.
Cause: Genetics, acne is a risk factor, spicy foods, stress, sunlight.
Symptoms: Redness on the cheeks and nose, enlarged blood vessels, hot skin, irritated eyes, swollen nose.
Contagious? No.
Treatment: Antibiotics, laser therapy, surgery.
WARTS
A skin growth caused by the human papillomavirus (HPV).
Who: Anybody, but nail biting, hangnails, broken skin, shaving and weakened immune systems are risk factors.
Cause: Physical contact (skin-to-skin or with a contaminated object).
Symptoms: Depending on the type of wart, the growth can appear on the hands, fingers, feet, face, genitals and, really, anywhere.
Contagious? Yes.
Treatment: Can eventually resolve on its own; over-the-counter treatments available; dermatologist can treat with excision, electrosurgery, cryotherapy and more.
This story appeared in Las VegasWeekly.
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How to identify and treat strange things that might be happening on your skin - Las Vegas Sun
A.O.C. and the Daughter Defense – The New York Times
Brett Kavanaugh invoked it. Mitch McConnell used it too. Matt Damon and Ben Affleck have each talked about it, and this week, Representative Ted Yoho joined their ranks: he, too, is now a member of the having-a-daughter-makes-me-an-ally-to-women or at the very least, should-excuse-my-bad-behavior club.
Having been married for 45 years with two daughters, Im very cognizant of language, Representative Yoho said in a speech on the House floor this week, denying that he called Alexandria Ocasio-Cortez, the freshman Congresswoman from New York, a fucking bitch after a confrontation on the steps of the Capitol.
Mr. Yoho later expressed regret for the abrupt manner of the conversation, in which he told Ms. Ocasio-Cortez that her statements about poverty and crime in New York City were disgusting. But, he noted, I cannot apologize for my passion or for loving my God, my family and my country.
On Thursday, in a speech on the House floor that has since gone viral in which she read the vulgarity into the Congressional record Ms. Ocasio-Cortez said, I am someones daughter too. She said shed planned to ignore the insults its just another day as a woman, she said but changed her mind after Mr. Yoho decided to bring his wife and daughters into the fray.
Our culture is full of platitudes about fathers and daughters: the Hallmark card, the weeping dad at the wedding. But invoking daughters and wives to deflect criticism is a particular kind of political trope and one thats been used throughout history to excuse a host of bad behavior, said the historian Barbara Berg.
The love a man has for the female members of his family, particularly his offspring, is presumed to have special power to humanize the other half of the population, to allow him to imagine the world his daughter will inhabit. Sometimes, in fact, this happens. Other times, the Daughter Excuse comes across mostly as cynical ploy.
As if familial affiliation alone equals enlightened attitudes towards women, said Susan Douglas, a professor of communication and media at the University of Michigan. Its like claiming I have a Black friend as if that makes you anti-racist.
There is social science thats shown there is something to being the father of a daughter.
In a study called The First-Daughter Effect, Elizabeth Sharrow, an associate professor of public policy and history at the University of Massachusetts, Amherst, and her colleagues, determined that fathering daughters and firstborn daughters, in particular indeed played a role in making mens attitudes toward gender equality more progressive, particularly when it came to policies like equal pay or sexual harassment protocols. The researchers also determined that those dads of firstborn daughters were, in 2016, more likely to support Hillary Clinton or a fictional female congressional candidate delivering a similar pitch.
Our argument is not that it is genetics or biology, but that it is proximity, said Dr. Sharrow. In other words: The daughters help the fathers see the problems they may have previously dismissed.
Witness basketball star Stephen Curry, who has written about how the idea of womens equality has become a little more personal for me, lately, and a little more real, since having a daughter.
Or Dick Cheney, whose views on same-sex marriage shifted earlier than many might have expected because of his daughter, who is gay.
And yet.
Daughters influencing fathers views for the better is far different from fathers using their daughters as shields and excuses for poor behavior, as Ms. Ocasio-Cortez described Mr. Yoho in her speech.
Its also different from fathers using them as props, as Dr. Berg puts it, to emphasize their alignment with womens causes or, by contrast, their disgust over behaviors perceived to be in opposition to them.
Consider Justice Kavanaugh, who during his testimony before the Senate Judiciary Committee about allegations of sexual assault by Christine Blasey Ford spoke repeatedly of his daughters (as well as his wife and mother) and noted that coaching his daughters basketball team was what he loved more than anything Ive ever done in my whole life as if loving coaching and allegedly treating women badly as a teenager are mutually exclusive.
Men have often pointed to their relationships with and love for some women especially wives and daughters to combat claims that they have mistreated other women, said Kelly Dittmar, a scholar at the Center for American Women and Politics at Rutgers University. We have seen this both inside and outside of politics, especially when men are subject to accusations of sexual harassment and assault.
In the wake of the 2016 reports on comments made by Donald Trump on the now-infamous Access Hollywood tape, a host of fathers-of-daughters came out to condemn the behavior. Mr. McConnell noted that as the father of three daughters he believed that Mr. Trump needs to apologize directly to women and girls everywhere, while Mitt Romney said that the comments demean our wives and daughters. (It is perhaps worth noting that Mr. Trump, too, has daughters.)
Similarly, in response to revelations of sexual misconduct by Harvey Weinstein, both Ben Affleck and Matt Damon, who had worked with the disgraced Hollywood producer, expressed their disgust on behalf of their female offspring. We need to do better at protecting our friends, sisters, co-workers and daughters, Mr. Affleck said on Twitter, while Mr. Damon explained that as the father of four daughters, this is the kind of sexual predation that keeps me up at night.
Women, too, have at times invoked mens daughters and other female relatives in trying to appeal to some men. When asked about Mr. Yohos behavior, House Speaker Nancy Pelosi said: Whats so funny is, youd say to them, Do you not have a daughter? Do you not have a mother? Do you not have a sister? Do you not have a wife? What makes you think that you can be so and this is the word I use for them condescending, in addition to being disrespectful?
The caveat, of course, is the qualification. Qualifying your outrage against misogyny as due to your role as a father or husband implies that, absent those roles, you would be either unaware of or unconcerned, said Dr. Dittmar.
Or as Ms. Ocasio-Cortez put it: Having a daughter does not make a man decent. Having a wife does not make a decent man. Treating people with dignity and respect makes a decent man. Why should daughters still have to be a prerequisite to respect?
Jessica Bennett is a Times editor at large covering gender and culture. She is the author of Feminist Fight Club and This Is 18.
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A.O.C. and the Daughter Defense - The New York Times
Female hair loss common and women shouldn’t be embarrassed to seek treatment, dermatologist says – ABC News
For most people, hair is not just about keeping their head warm and for protection from the sun; it is a mark of youth, vitality and how we present to the world.
Losing hair at any age can be very confronting, and for many women it can be hard to simply shave it off and embrace the bald look.
Dermatologist Clare Tait told Jessica Strutt on ABC Radio Perth that she has been seeing many female patients seeking hair loss treatment.
"Our appearance, and how we present to our family and our friends in the community, is very important and the head of hair is one of the most visible aspects," she said.
"Ever since I've been a dermatologist there's been a constant demand for women seeking help for hair loss."
Dr Tait said more women than ever have been seeking treatment when they noticed they were losing their hair, but that may be because they are increasingly aware that help is available.
"I think it is partly an awareness that that there are things that we can do, and that it is a very legitimate concern," she said.
"I think it's also that there is a greater emphasis in our society today on how we look and how we appear youthfulness is highly prized and a youthful look is often equated with a full head of hair."
While a person's appearance may be seen as a trivial concern, or the domain of late-night TV ads, Dr Tait said no one should feel uncomfortable about seeking medical treatment for hair loss.
"I think that it's quite common and that sometimes people are embarrassed and almost feel ashamed to be seeking help for something that they perceive is a cosmetic issue only," she said.
"If it's causing anxiety, if you feel it impacting on your quality of life, then that is the time to seek help."
Androgenic alopecia, often better known as male or female pattern hair loss, is fairly common, Dr Tait said.
"It is an interesting condition because it's almost statistically normal for women to develop this condition, particularly after the menopause, with a generalised thinning of hair and sometimes some increased shedding as well," she said.
"Probably about 40 to 45 per cent of women by the age of 50 are noticing some thinning."
Many people believe stress is the cause, but Dr Tait says that while stress can exacerbate female pattern hair loss it is unlikely to be the root cause.
Female listeners anonymously texted their hair loss stories to ABC Radio Perth:
"I'm 46 and lost all my hair to alopecia 5 years ago. I feel like I have a handle on wigs, though they'll always be a pain to wear. I really miss being able to tie my hair out of the way in a ponytail. What I really struggle with is doing make up without eyelashes I feel like I have no idea what I'm doing."
"My hair fell out at menopause. My hair was thick so my doctor didn't take me seriously. I started keeping the fallen hair in a bag and presented it to the doctor he finally took me seriously. Hair loss is cyclical; [it] happens every eight years or so. [My] last fall [was] about a year ago another bag of hair. It never quite grows back as thick."
"I am female in my 60s and have long, thick hair; [it's] always thick and shiny. Eighteen months ago it started falling out more than normal. Testing revealed severely low iron levels. Two infusions of iron, along with [the] removal of all caffeine from [my] diet, [and] six months later it [my hair] was back to normal."
While many women may lose hair due to their genetics, an iron-related condition called telogen effluvium can also be a commonplace cause.
"It is absolutely correct that iron deficiency is one of the commonest causes of this condition," Dr Tait said.
"I would routinely test iron levels as well as a number of other things to make sure there's nothing that's easily reversible and that will help the hair grow back."
In cases where it's not just hair but eyebrows and eyelashes that are falling out, Dr Tait said it was more likely a condition called alopecia areata.
"That's a completely different condition that requires different treatment," she said.
Dr Tait said it was not uncommon for patients to stop washing their hair as they attributed the washing to their hair loss.
"A lot of people that I see who are losing their hair to tell me that they have stopped washing it, or wash it much less frequently, because they're concerned that washing their hair makes it fall out more," she said.
"When we wash our hair we do lose more hair on that day but overall it balances itself out.
"I can reassure people; how often you wash your hair will not have any long-term effect on how quickly you're thinning or how much hair you're losing."
When you get older your hair and nails change. Will diet or supplements make a difference?
Dr Tait said the same was true for using hair dryers, hair straighteners and dying hair.
"If you're over-drying hair you may find that the shaft becomes more brittle," she said.
"It may break off more easily but neither of those things will stop the hair growing.
"Providing you're not having any reaction from your hair dye, and you're not getting an itchy, irritable scalp, it's perfectly safe to dye your hair with these conditions."
Dr Tait said she hoped more women would realise that it was possible to seek treatment if their hair loss was bothering them.
"I think that's really very appropriate that people do come and ask what can be done about it and let us know how it's distressing them."
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Female hair loss common and women shouldn't be embarrassed to seek treatment, dermatologist says - ABC News
Economic fallout from pandemic will hit women hardest – The Guardian
Even before the coronavirus pandemic, there were vast inequalities between men and women in the world of work. Despite chipping away at the glass ceiling over recent decades, in 2020 the gender pay gap still remains stubbornly high, while more men called Steve and Dave run FTSE 100 companies than women.
Four months from the launch of lockdown, and as Britain slips into the deepest recession for three centuries, it is increasingly clear the economic fallout from the pandemic is having a disproportionate impact on women.
Decades of progress although very much incomplete risk being unwound, in a crisis that has shone a light on a myriad of social and economic issues. Earlier this week the International Monetary Fund warned that if left unchecked, 30 years of gains for womens economic opportunities could be erased, and called for governments around the world to take immediate action to prevent longer-term damage.
Working mothers in particular are bearing the brunt. Centuries of structural social convention have ensured the tasks of childcare and homeschooling are more likely to fall on their shoulders, while the demographics of employment in the worst hit sectors of the economy such as hospitality and retail mean women are more likely to lose their jobs.
Given the scale of the economic shock, the governments economics forecaster, the Office for Budget Responsibility (OBR), estimates that unemployment for both men and women will more than double by the end of this year to the highest levels since the 1980s.
The government is, however, preparing to scale back its emergency response to the economic shock from next month, as Boris Johnson attempts to secure a return to normality in time for Christmas, despite warnings over a second wave of Covid-19 infections and more job losses this winter.
To kickstart the recovery, billions of pounds in tax cuts and spending measures have been promised by the chancellor, Rishi Sunak. But experts say much of the money will miss the mark. The Womens Budget Group argues much more investment in social infrastructure including childcare and social care is also required to stimulate growth.
Since the onset of the pandemic, as many as 9.5m jobs at 1.2m companies have been furloughed on the Treasurys furlough scheme, which pays 80% of workers wages, up to 2,500 per month. A further 2.7 million claims have been made by the self-employed. Both schemes will, however, be closed by the end of October, with at least 10% of furloughed jobs expected to be made redundant.
Official figures show men are more likely to be furloughed, in part because women have typically continued working through the crisis in education, health and social care jobs sectors where they are over represented. The TUC estimates that out of 9.8 million key workers putting their health at risk on the frontline, nearly two-thirds are women. However, as many as 2.6 million female key workers earn less than 10 an hour.
Before Covid-19, there were signs of progress towards a more balanced, modern workplace as the number of women in work surged to a record high, including record numbers of working mothers. Despite this, official figures show men still earn 17.8% more than women on average across the whole economy. The Fawcett Society estimates it would take 60 years to eradicate the gender pay gap on pre-crisis trends. But given the scale of the economic shock for women currently unfolding, it expects parity to be delayed by three decades until the year 2110.
As unemployment begins to rise, experts warn job losses are likely to be disproportionately felt by women, given their prominence in sectors hardest hit by the crisis such as hospitality, leisure and retail. Globally, the International Labour Organization estimates that almost 510 million, or 40% of all employed women, work in the four most affected sectors, compared to 36.6% of men.
In Britain, young women in particular are overrepresented in these sectors: 36% compared with 25% of young men. Overall, 17% of women compared with 13% of men work in hospitality, leisure and retail, at a time when barely a week goes by without a big high street name announcing redundancies.
Combining these workforce demographics with longstanding social norms, experts believe mothers are one-and-a-half times more likely than fathers to have either lost their job or quit since lockdown began.
Working mothers in traditional nuclear families have taken up a greater share of domestic work and childcare in the hours usually occupied by employment. What with juggling Zoom meetings, home-schooling and lunch times, mothers in two-parent households have been doing a third of the uninterrupted paid-work of fathers on average, according to the Institute of Fiscal Studies. Mothers are doing two fewer hours of paid work each day than fathers, but two more hours of childcare and housework.
The closure of schools and nurseries further exacerbated the unequal distribution of unpaid care work before the pandemic. But experts warn these trends will persist when offices begin to reopen from 1 August, worsened by the anticipated closure of 10,000 childcare providers crushed by the coronavirus crisis.
This will inevitably create a two-tier recovery with men getting back in to the labour market at a faster rate than women, said Mary-Ann Stephenson, director of Womens Budget Group. If the government is committed to getting the workforce up and running, then care and women must be at the centre of any economic recovery plan.
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Economic fallout from pandemic will hit women hardest - The Guardian
Berkeley Talks transcript: Why racial equity belongs in the study of economics – UC Berkeley
Suresh Naidu: Okay. Ill get us started. Thanks everyone for showing up. Thanks a lot to our panelists for agreeing to do this. Just as a few words of background, my name is Suresh Naidu, the co-organizer of Economist for Inclusive Prosperity, which is a project Gabriel Zucman and Dani Rodrik and I started kind of trying to explore what economics looks like after neo-liberalism and what kind of a more inclusive, more egalitarian kind of economics looks like.
And this is kind of our attempt to sort of help economics grapple with its current moment by acknowledging that economics doesnt necessarily already have all the answers and doesnt already have the necessary conceptual toolkit. So, theres lots to say about this, and lots of people here that have thought about it more than me, and so Im just going to hand it off to someone whos thought about it a lot, Sandy Darity, who is going to be moderating the panel. So, take it away, Sandy.
Sandy Darity: Thank you, and thank you to you Suresh and to Dani for organizing this event. I think its very, very important for us as economists to learn from the other disciplines. Weve had an imperializing tendency towards the other disciplines, and in the process I think we have failed to really recognize many of the important contributions that have been delivered from other disciplines using their perspective rather than the perspective that we normally bring to these issues.
In particular, Im struck by the fact that an important tool that Ive used in much of my research, the Blinder-Oaxaca decomposition, really I believe was preceded by the Blau and Duncan decomposition in sociology, but I think frequently we have not been aware of that.
And similarly, when we talk about unobserved heterogeneity, it sometimes becomes a blockade for really understanding the phenomenon of discrimination. Or when we talk about the identification problem, it constitutes a blockade to thinking about some factors as being fundamental causes of phenomena rather than interactive causes of phenomena.
So, as a consequence, I think its really going to be valuable for us to hear from the scholars who are going to join us today. We have four speakers after they make their respective presentations, we will take questions from the floor, so to speak, and have an opportunity for the speakers to respond to those questions as well as engage with one another.
And our first speaker is going to be Daina Ramey Berry, who is the Oliver H. Radkey Regents Professor of History at the University of Texas at Austin. Her superb book The Price for Their Pound of Flesh, recovers the humanity or persons, Black persons specifically, whose lives were comprehensively commodified.
There are two additional dimensions of her book that I think merit deep attention. First, the extended commodification of Black bodies after life ends into death; and second, the significance of the effects of markets, markets in human beings on U.S. economic development. Her most recent book is A Black Womens History of the United States, co-authored with Kali Nicole Gross.
And Im hopeful, time permitting, that shell have an opportunity to tell us what we can learn from that book also. Our second speaker is Arjumand Siddiqi, who is an epidemiologist at the Dalla Lana School of Public Health at the University of Toronto. She is also the Canada Research Chair in Population Health Equity.
She has had brilliant insights about differences in social and policy structures across countries and how they affect not only health outcomes for the general population, but also the health disparities between ethnic and racial groups within those populations.
She also has recently published a critique of Case and Deatons perspective on deaths of despair, and in the interest of full disclosure, Im actually a co-author on that article. But she has a strong commitment to understanding the full play of what public health scholars refer to as the social determinants of health in contrast with genetic or behavioral or cultural factors.
Our third speaker is going to be Mario Luis Small, who is a deeply accomplished sociologist, urban sociologist at the interface between thinking about neighborhoods and communities as well as social networks. He is the Grafstein Family Professor of Sociology at Harvard.
And one of the things thats particularly impressive about his research productivity is that two of his books Villa Victoria and Unanticipated Gains both have received the C. Wright Mills Award. I think recently in some of his work, hes been most notably engaged in a nuanced reintroduction of cultural considerations in the analysis of race and sociology.
And then our final speaker is Eduardo Bonilla-Silva, one of my colleagues at Duke, also a deeply accomplished sociologist. Remarkably, he has recently served as president of the American Sociological Association and the Southern Sociological Society simultaneously. I think thats unprecedented.
He is the author of Racism Without Racists, among a number of books, but I want to mention Racism Without Racists because its now in its fourth edition. And it explores the difference between peoples attitudes about race thats expressed in short answer surveys versus in-depth interviews.
And what he demonstrates in that book is that if you rely upon short answer surveys to try to gauge variations in peoples attitudes on questions concerning race, youre going to miss the boat because theyre self-censored increasingly. And so, what you really want to do is engage them in long-term interviews, and in that environment you get much better information about what their beliefs really are. So, may we start. Daina Berry, please.
Daina Ramey Berry: All right, thank you so much for having me. Im going to start off my brief remarks to just talk a little bit about what the work looks like from an historians perspective. And as Dr. Darity said, my research is on enslaved people. And I was an economics major during undergrad, I dont know if Dr. Darity knew that, but I was a major in economics until my last year in undergrad, and I took an African American history class and decided thats what I wanted to change and do my work on.
But Ive always wanted to try to find a way to blend the work that I had done as an undergrad in economics. So, when I started doing this work on The Price for Their Pound of Flesh, my goal, maybe it was naive, but my goal was to allow the economists that are doing work on slavery, very big work on slavery, to have a more cohesive conversation with historians.
And one of the things that I was trying to do initially is I was trying to walk in the space that I thought economists do, and I was trying to find out whether or not I could show statistical significance in my findings. And as I was doing that and trying to search for that in the ways I was looking at how enslaved people are priced from the beginning, before theyre even conceived.
So, enslaved mothers were looked at for the fecundity to see what their value of their future laborers would cost, to see whether or not if they had given birth to children, did those children survive to age 5? Were they healthy? And if so, that particular woman received a higher valuation during pregnancy than other women. And so, I was doing research on that and trying to look at ways to bridge this gap between the two fields, and to make sure that my argument would be palatable in both spaces.
And what I learned in the process was that enslaved people spoke very loudly to me when I was looking at these records, and I was using datasets that Stanley Engerman and Robert Fogel created. Id also created my own dataset. Ive been doing research in Southern archives for about seven or eight years, and had this large data set of about 80,000 individuals enslaved peoples values, their prices, their monetary values and their appraised values.
But I realized as I was doing this work that enslaved people themselves had so much more to say about valuation and the values on their bodies. And that was really interesting to me, and I thought, Okay. Well, if I write this book that talks about it from the perspective, enslaved people participating in their thoughts about the value of their bodies, how will that change the way we talk about this in both economic and historical circles?
So, I dont know how its fully been received in economic circles. I have a very good economic historian friend who said to me, That is not the book I would have wrote, when I finished it, because theres a lot of testimony, theres a lot of stories of enslaved people saying, Oh, Im not worth $500, Im worth $200, or, Im not 40 years old, Im 20 years old.
So, this is an economic product thats put in a market space that has the ability to argue, to emote, to reject, to resist, and that is a very, very different product. And one of the things that Ive found, its a human product, right?
And when I was doing the research for the book, I saw that the work that Ive used from a number of economic historians did not acknowledge at all the humanity of enslaved people, and I thought, even if youre not writing about them as human beings, but youre putting them in formulas and they now become a person named John, now becomes an X with an exponential power and theres a formula to figure out how much that particular woman is worth or that particular man is worth, it doesnt take much.
And I think youll have more historians engaging this work if you acknowledge that this was a family, and this person lived on this particular plantation, and they were worth this much, and this is what they felt about their documentation or how they responded to that particular moment of sale. And that was really what the book, the purpose of the book for me. But what I found later, and I think Dr. Darity mentioned this, was that the valuation of enslaved bodies went beyond preconception, but also to the postmortem space.
And that there was an illegal trade in cadavers of enslaved people and whites and free Blacks, but I was mostly interested in the enslaved cadavers their bodies were sold to medical schools, and so they still made money off of their bodies after they had passed away. Some of them the values were much lower, anywhere from $5 to $30.
So, the market rate wasnt as much, theyre valued more when theyre living because theyre producing more, right? Theyre producing more and bringing more financial resources to the families that theyre enslaved by, but in the afterworld, Okay, Im going to dispose of this body. If I can make some money off of the disposal, Ill make $30, and thats it.
There were some cases where enslaved people were valued at the moment right before they were hanged, and then the surviving relatives of the plantar family or the enslavers would receive compensation for the valuation of that enslaved person. So, theres a lot of spaces where we talk about slavery and enslaved people, and we talk about them in monetary ways, but the humanity is often missing and theyre objectified theyre treated like a backpack or a book on a shelf.
And I just feel like if economists and historians can come together and have conversations about the deep meanings that you guys find when you create formulas, you can take us to places that we cant go, but we can also bring you to records that might inform what youre seeing and how you analyze this work and make it for a much deeper conversation.
So, I will leave it at that. I dont know if Ive done my five minutes, Im trying to stay on it. If I have a little more time, I could say a few more things. Im good? All right, thank you. Im looking forward to the conversation.
Sandy Darity: Thank you. Arjumand, youre on mute. Okay, youre off now.
Arjumand Siddiqi: Great. Thanks everyone. I feel like I should put out a disclaimer that says some of my best friends are economists before I start my talk. So, as Sandy mentioned, Im a social epidemiologist, and our discipline is really quite related to medicine and to the study of distributions of disease from a sort of clinical perspective.
And so, as social epidemiology kind of evolved, we were starting to find our empirical legs around how to use population surveys and different kinds of data than the clinical data our discipline tends to use, how to use different statistical methods.
And in the early 2000s when I was doing my Ph.D., I remember sort of looking enviously from Boston over to Cambridge at the economics department because it was considered so rigorous of all the disciplines related to our field.
And then, I had this moment of pretty big dissonance when in the mid 2000s, I encountered a paper by three economists whose main argument was that Black/white differences in hypertension could be attributed to genetic selection for genes associated with salt retention.
And the narrative was that this genetic selection occurred during this transatlantic slave because of the survival advantage conferred by salt retention, and that it occurred during cheap-looking tests for salty skin done by slave traders to further determine what Blacks would be able to the demands of plantation work.
And this economist team also suggested that this salt retention hypothesis was really the best way to explain the Black/white life-expectancy gap as well. Its been a lot of years, and I actually had trouble finding the paper online now, but I just remember thinking that the evolutionary geneticists just probably were passing out at the notion that genetic selection would occur at that pace.
Something that occurs over thousands of years was essentially being proposed to happen over one or 200. The human genome scientist who had carefully explained to us by then that race was not a genetic construct, there was no genetic basis for race, and just thinking to myself, Surely, there is a geneticist amongst the authors, or, Surely, some of the genetics work on race has been cited, and it hadnt, and it was just really difficult to understand how a hypothesis that had no premise could receive so much traction.
The paper also was a little bit alarming because it hadnt cited any of the work from social epidemiology on racial inequalities in hypertension. And Im not just sort of suggesting that my field is the field that should be cited, but we really are the central field on racial health inequalities. And there are people who have specialized their whole careers on racial disparities and hypertension, none of them were cited.
And if they had been, you might find a very different story about Black/white differences in hypertension and in life expectancy. So the body of literature in our field thats been built up is both based on what we know race is not, as well as what we know race is. And the idea is that weve built up sort of a conceptual and theoretical basis, but also a lot of empirical tests of the propositions that have been made.
And what the field has found is that racial inequalities in health manifest through processes of structural or institutional racism, as well as what is often called everyday discrimination. So Black people are systematically denied access to material resources and are subjected to chronically stressful experiences of daily life, and those things together put them at a higher risk of a wide range of illnesses and death.
So, social epidemiologists would and have told a very different story about Black/white inequalities and hypertension and life expectancy. Lately, my colleagues and I have been working on the noted rise in white mortality in the U.S., whats been called the deaths of despair phenomenon, the paper that Sandy mentioned earlier. There are a lot of teams working on this, including economists Anne Case and Angus Deaton, and youd better believe we take their work very seriously.
We have carefully looked at their hypotheses, we have carefully cited them and so on. And in some ways I think I live in fear of making facile arguments simply because Ive been both careless or dismissive of work from other disciplines. And Im increasingly of the mind that maybe this fear is a good way to approach scientific inquiry, and Im increasingly weary when I read work that sort of doesnt cite anyone else outside their own discipline, especially when its topics that are not central to their discipline and their expertise.
So, back to that deaths of despair work. So, in that piece we propose that status threat, group status threat, the sense from whites that they are losing relative status compared to Black and brown people is accounting for the rise in white mortality. And we use, in this paper, both theoretical and empirical findings from social psychology and from political science to suggest that at the population level we can actually measure, or proxy status threat by measuring the rise in the vote share going to Republicans in any given county.
So, our model essentially tested whether rise in Republican vote share at the county level as a proxy of status threat could predict the rise in white mortality accounting for about 17 social and economic indicators, fixed effects and so on that might also be involved in the processes. So, we received quite a bit of pushback on this paper in two ways, and the first was that it was just a bridge too far to equate Republican vote share with status threat.
And the other was that because of our statistical model again, 18 variables, county time, et cetera, fixed effects because the model did not account for unobserved confounding, that we couldnt interpret the association as being causal.
So, the fundamental problem I see with this argument is not that it suggests there might be an alternative explanation, I totally concur that there might be, but its the idea that an unknown alternative explanation that no one is proposing, its just the idea that there might be an alternative explanation is given equal weight to a model that tests basically everything we know about how the world works. And so, I worry a lot that this notion of unobserved confounding is actually overtaking or being weighted equally with the preponderance of evidence that we have, and Im not sure that thats a great way to go.
You also see it, as Sandy mentioned, in models where there are residuals and accounting for race-based differences and the implication given the preponderance of the evidence would be that these are discrimination effects. And yet, theres a reticence to think about that or at least to weight it equally with the idea that theres some unobserved confounding, theres this sort of unobserved confounding boogeyman out there that we think live by too closely.
A final anecdote about our field, and I think what it says about economics. So, I had a graduate student who wanted to work on racial differences in the distribution of birth weight. And in fact, she wanted to look at whether Canada and the U.S. have different inequalities in the distribution of birth weight. And the idea was that if we compare countries in their inequalities, we might start to point to some of the societal factors that are modifying inequalities, that are mitigating them or exacerbating them.
And I spoke to an economist colleague of mine, whos a lovely person, and he said, Im a little worried that were not going to get very far in terms of a causal association if we pursue this line of questioning, that youll really only be able to say associational things. Why dont we look at how prenatal care affects racial inequalities in birth weight? Which is a fine question, Im not disparaging the role of prenatal care. But imagine the difference in the size of the question and the focus of the question between something that talks about how societies produce, fundamentally produce, inequalities down to something that deals with a fairly circumscribed issue.
And so, my worry is that this chase after causal inference precludes us from looking at a lot of really important questions. Im not suggesting we go down the road of looking at those questions and imply causality when it isnt there, but I do think that we can pursue those questions and say something about what the causal inference issues are and how to push ourselves, but not to completely ignore what I think are really, really important questions for society. And Ill leave it there.
Sandy Darity: Thank you. Mario, please.
Mario Luis Small: Thank you very much. This has been very interesting so far. So, Ill tell you that the main reason that Im here is probably because a couple of months ago I published a paper along with Devah Pager and the Journal of Economic Perspectives titled Sociological Perspectives on Race Discrimination, and the point of the paper was to make a case for six ideas in our field, sociology, that economists havent, but probably should, take seriously. So, what Im going to do is give you three of these ideas and then after of course the last talk just open it up.
So, everybody here knows better than I do that traditionally economics, kind of two standard models are the taste discrimination and the statistical discrimination model when people study race discrimination, and I dont have to tell you what those models are. But one thing I will say is that from our perspective, there are a couple of quite important problems with those models.
And I guess you could sum them up with the idea that a model or a set of models that studies discrimination by focusing on the potentially racially motivated actions of an actor making decisions today, will probably understate a lot of the ways discrimination actually happens and has consequences for even the things that economists care about.
And this is the case for at least three reasons, the first Ill say is that it ignores the possibility of institutional discrimination. And Im going to use that term in a very narrow sense to refer to differential treatment by race that is either perpetrated by an organization or qualified into law.
And I am not using the term structural racism or institutional racism, or a lot of stuff that other sociologists have used and a lot of people in the media have used because theres sort of ambiguity in some of these uses of the terms, and they dont always mean what we were meaning, what were referring to, but just very narrow the idea that differential treatment by race can be perpetrated by the organizations recorded according to law.
And so, to give you a very simple example, sort of take an organization in which nobody, as Becker would say, nobody wants to pay a price to not associate with people of a different race, so nobody has a taste for discrimination. And in addition, nobody is willing to make statistical inferences about the behavior or likely performance of an employee on the basis of the employees group, so nobody statistically discriminates.
Now, lets assume that that firm, as many do, hires new employees on the basis of referrals, that they have an incentive system. For example, depending on the level at which youre hired, for entry-level employees, youll get a hundred if you refer somebody and they get hired. Now, lets assume we also know sociologists have shown that theres racial homophily.
I think in economics, this is called a sort of mating-by-race and friendship formation, but basically the idea that people tend to have friends of the same race. Now, if this firm is racially homogeneous, whats going to happen is all of the people who come in applying for jobs are going to be other people of the same race because of the pattern in the world, and we could see the strong incentives made for people to be hired on the basis of the people you already have.
In this model, no employer has to have a taste for discrimination or to discriminate, and yet a highly qualified person of a different race from outside the firm is going to have a very small chance of getting a job there. Thats a form of discrimination that we believe deserves attention.
The second point Ill make is that, again, the reason its a bad idea to just focus, or yeah, just a bad idea to only limit the story of discrimination to only the actions of our contemporary actor is that a lot of forms of historical discrimination, particularly forms that have been codified into law or become institutional parts of how organizations operate, continue to have effects today.
And therefore, even if today everybody stopped being discriminatory either by race or statistically or whatever the case may be, wed still have a lot of reason to study historic discrimination to understand the present. I wont go too much into this other than to say that a very clear example of this is redlining that many of you are familiar with. There have really been quite a few papers, including a couple by economists in recent years, showing that redlining practices back in the 30s can be shown to have likely had a causal impact on long-term homeownership rates among African Americans and segregation detectable even today.
And so, there have been papers that, for example, have looked at the boundary line for redlining and units on either side of it, theyve looked at federal policies that had cutoffs for the size of the town and looked at towns slightly older and slightly bigger and smaller than that through multiple indication strategies, such as quite a bit of evidence that it matters.
The last point Ill make is that, again, a different reason to not limit the study of the discrimination to sort of statistical and taste-based discrimination is that perception of discrimination matters, a lot. And what Ill say when Im saying this is that I am not saying that perception is an effective substitute for actual discrimination, and Im also not saying that we should not continue having a healthy skepticism for what people say over what they do, but what I am saying is that there are many contexts in which the perception that an employer or a doctor or take your pick, has or will or has had discriminated, this can affect your behavior in ways that matter for where you apply for jobs, how far you go in school and sort of what your health outcomes are, that we can not capture, again, by focusing on the employer or the banker as a prototypical racial or potentially racially motivated actor.
So, Ill just leave it at that. And Ill say, if youre interested in more of this, Ill refer you to the JEP Paper. But the bottom line is I appreciate, actually, I find quite interesting a lot of what economists have done in this. I think the issue is expanding beyond whats been done as opposed to remaining tied to these two very traditional ways of looking at discrimination. Thank you.
Eduardo Bonilla-Silva: Okay, its my turn. So, economists begin with this notion of the free market invisible hand, and we need to be clear that the hand has a color its a white hand, let me say white male hand. I will not address the gender components of the market, Ill leave that to others, so I will only talk about the racialized aspects of the market. Yeah?
And like Daina, I also will say that I was a major in sociology and economics, and that was the main thing I ended up choosing sociology, in part because of the foundation of economics is assumptions about the rational actor making decisions on a cost benefit basis in something called efficient market. And we all know that the homo sapiens theyre a complex animal shaped by multiple social forces and group divisions.
I do believe, I mean that my masters and my old magazine remains with me, so economic factors account for a lot of what happens in life, but cannot explain everything because the material component of life cannot be defined in these narrow economics way in which many of you sort of structure your analysis. So, the white homo economicus, for example, as we have learned, cares about access to parks, control of neighborhoods and schools, and their culture.
They are willing to fight tooth and nail to keep certain status in place. They like to feel good about themselves because Blacks, as Mara will argue a long time ago, have served as the symbolic index for whites, they can always say, At least I am not Black. And that element of feeling good about yourself is important in life. So, whites are so invested in whiteness that many are willing to die for it as Jonathan Metzl outlined in his recent book.
So, this is the stuff of history. Yeah? We have modernity, and modernity was not just driven by capitalism because in capitalism, as Eric Williams, Cedric Robinson and many others have argued, you cannot undo the connection between slavery, genocide, land theft and the economic model production.
In the case of the U.S., we had slavery, we had genocide, we had land theft, we had and we still have colonialism. As a Puerto Rican, I know that this person doesnt represent my interests, and two days ago we learned he was wondering about selling Puerto Rico. And of course, workers of color have allowed capitalism or capitalist to extract separate super profits from us.
So, that means that the society structure and culture were racialized on the get go, and I suggest not only produce systemic racism, but that system remains. So what is systemic racism? It used to be so easy: Its the bad guys. Its the new bad guys, its the rotten apple theory of life. This people having a taste for discrimination.
The trick is understanding that systemic racism ultimately cannot exist without the actions and inactions of the green apples, that is most whites participate consciously or unconsciously in the systemic racism stuff. And lately, literally two months ago, everybody seems to be talking about systemic racism, but I think most folks talking about it dont know what theyre talking about.
So, for example they say, Police departments have systemic racism, I mean, merely with the caveat, but most police officers are not racist, therefore reversing or reverting to the theory of life of the bad apples. In truth, the way that we select officers, the training, the culture, all these things shape the actions and beliefs of the officer.
So, even the good ones, and I put that in quotation marks, carry out race-based policing. And I wanted to give you a liminal example. So, this is a young African American college student who was brutalized in Atlanta recently by six police officers, and you can see only one of the officers was white.
So some of you may be thinking, But can Black people enforce white supremacy? And since slavery, many Blacks have been selected to participate in the enforcement of white supremacy. And although, historically, the main people in charge of enforcing boundaries happen to wear the white uniform, and not only white police officers, but regular white folks, in truth, thats the way that the system works.
And thankfully, because we humans, our subjectivity is shaped by multiple factors, there is always a space, a possibility for change. So, what we need is a historically specific view of racism that allows us to also understand that the systems share basic features. Whether theyre wearing Panama, Puerto Rico, Haiti, or the U.S., all the systems share basic features.
But we need to be specific about how racism is structured in a particular society. In a society, you can have regional variations, if you think about the U.S., the South, North, West, and we need to be also time specific. Dont assume that there is one racism throughout history racism can change.
The rules and regulations of the slavery regime were different than Jim Crow, and they are different from what we have today that Ive called in my work, the new racism. Secondly, the systemic racism forms a structure. Systemic, collective practice, behaviors and culture that reproduce disadvantage for some and advantages for others.
And here comes the hardest part, which is understanding that this system, as material foundation, it remains in place like capitalism, patriarchy, because systemic racism, because folks benefit from it. Again, I already showed or suggested that there are fractures in the white communities of possibilities for change, but we need to understand the big implication which is that racial domination depends on nice, good white people who participate in various ways and to different degrees in maintaining the racial order of things.
Borrowing the work from Marx and Poulantzas, the whites are personifications of systemic racism. So, they receive mostly in passive or neutral ways what David Roediger called the wages of whiteness. They follow the dominant racial script. So, contemporary whites, they live in white neighborhoods, they have only white friends, white schools, white ideas, white everything. Yeah? They even eat white bread. Thats a joke.
And lastly, they keep trucking along as if racism was a prerogative of the races. They input signs in their yard saying, We believe black lives matter, but we live in a totally segregated neighborhood. So, final out words. If racism is systemic, then as Mario was articulating, it cannot be just a taste or a matter of statistical discrimination. Its not an individual phenomenon, but a collective practice.
And I think that you also need to understand that the actors, and thats the reason why I moved from economics sociology because economics focus on the individual actor, sociology is more likely to see sort of collective behavior. So, actors belong to groups and experience life in group-structured condition. So, many of our explanation, for example, for the status of people of color, and Im doing what William Ryan called eons ago, blaming the victims, and by doing so they ignore the system. For example, they claim that Blacks dont do well in life because of their culture.
So, Oscar Lewis wrote one of his first books on Puerto Rico, Puerto Ricans, La Vida, claiming that the reason why poor Puerto Ricans here in the world, actually why Puerto Ricans here in the world, he defines us, the population, was because we have the culture of poverty.
And that argument, the culture of poverty, is like Freddy Krueger. You think you have killed the culture of poverty and it comes back with a new attire. Or the claim, Youre not doing well because of female-headed households, or, Its class, or as Daina was talking about, it is They have salt in their bodies.
And a lot of people were using that little graph as evidence because presumably it shows a slave master tasting a Black person to see if they are salty. Alternatively, and we dont know what this person had in mind, but weve got to think that person was a pervert. And theres a lot of work showing that slavery included the abuse, sexual and otherwise, of both women and men.
So, it is anything but racism. I think its time for us to take racism seriously analytically, politically and morally as many folks are doing right now in the mean streets, to cite Piti Thomas, of America. So, thats it for me.
Suresh Naidu: Thanks.
Sandy Darity: Suresh, its in your hands now.
Suresh Naidu: Yeah, so thanks to all of our panelists, that was really interesting. So, now wed like to take questions from everyone. So, if you want to raise your hand, and I will do my best to keep up, we dont have the questions function here so its going to be a bit of a So Im clear I wont see everyone, but if you want to use the raise hand function in the tab and I can take questions and call on you. Peter.
Peter: Yeah. I just want to say thank you all so much for these really excellent presentations. And Mario, my students and I read your paper, and I think that we as economists certainly have to broaden our perspective. My own view is that we tend to rely a lot on models, and so the call to action really is to think about new models of discrimination as a way of trying to instantiate some of these ideas into the profession.
And then the second piece, too, is whenever we write models, they need to be historically accurate, right? Like for some reason, its like we write models with really terrible assumptions that have no basis in history, for example, that discrimination happens on the margin, when in fact you had signs saying No Blacks, regardless of your socioeconomic status.
So, thank you all for organizing this panel, thank you for your work. I look forward to continuing to read and to engage with your work, and I certainly hope that the ideas here really permeate our profession in a foundational way.
Suresh Naidu: Great. Okay. Does anyone want to respond, or I can keep taking questions? Felix.
Felix: Hey, everybody. Thank you everybody who is participating for your thoughtful words and for organizing. I guess I wanted to ask a little bit Im a Ph.D. student who does research on race and my training is in economics, my degree is in public policy. I have, as I think some people have mentioned, Ive faced pushback, right?
I think when you think about who is in economics, Ive had the experience of people being in that room who think differently about these things and dont sort of take the standard economic view as given and are looking at these other disciplines, thinking about those things.
Those things are not received well, right, which is I think why you dont see them published or sort of like being sort of the output that you see off the field, and some things that are on their face ridiculous, end up being received better because of sort of power.
I guess my question is, number one, is economics just weird or particularly, say Im white and its power structure or some other thing that makes us very susceptible to things, are these kinds of things in ways that you guys might not be in the disciplines that you sit in or do you guys have strategies that have allowed you to do this kind of courageous work that challenges power in important ways and still sort of make it out on the other side?
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Berkeley Talks transcript: Why racial equity belongs in the study of economics - UC Berkeley
Can You Safely Have a Vegetarian Pregnancy? Health Essentials from Cleveland Clinic – Health Essentials from Cleveland Clinic
There are many benefits of plant-based eating. But is it safe to exclude meat when youve got a whole-grain bun in the oven? Registered dietitian Julia Zumpano, RD, shares her tips for being a pro at pregnancy while still being pro-plants.
Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services.Policy
Vegetarian diets are nutritional powerhouses because they are:
The tricky part of eating vegetarian while youre pregnant, explains Zumpano, is that your protein needs increase during those months.
Zumpano says the average pregnant woman needs 71 to 75 grams of protein a day during pregnancy. That number can be even higher due to a number of factors, including if youre carrying multiples. If you want to eat vegetarian during pregnancy, its best to see a dietitian for a personal assessment to know your specific protein needs.
Its definitely doable to eat vegetarian while pregnant I did it myself but you need to plan your meals around protein to ensure youre getting enough, which may also include protein supplements.
A vegetarian diet typically cuts out meat, but there is a lot of grey. Some vegetarian diets include eggs and dairy. A vegan diet has no meat, dairy or eggs. A pescatarian diet is plant-based but includes fish. Is one type better during pregnancy?
If someone is open to less restrictive eating during pregnancy, I try to guide them that way because it can be easier to fill the nutritional requirements, says Zumpano. For example, if someone is vegan but open to dairy during pregnancy, I would encourage that shift so they can get their protein and calcium needs met by food sources.
If youre set on a vegan pregnancy or dont want to adjust your eating habits, youre still good. Youll just need to use a supplement or a vegetarian product like tofu to meet the nutritional needs of you and your baby.
All pregnant women, whether or not they eat meat, need to take a quality prenatal vitamin. If the vitamin doesnt contain enough calcium or folate, you may need additional supplementation.
A high-variety diet can help you meet your nutritional requirements in pregnancy:
There are also some foods you should avoid:
If you want to ensure complete nutrition during a vegetarian pregnancy, its best to plan ahead. Zumpano recommends making a list of the fruits, veggies, proteins and grains youre willing to eat and then planning your meals around them.
Probably the hardest time to successfully eat vegetarian is during the first three months of pregnancy, says Zumpano. If you have morning sickness or nausea, food may not taste good. Or you dont feel like eating for fear it will all come back up. It can be almost impossible to eat a complete diet in this situation.
To avoid having soda crackers as your primary food source, Zumpano recommends:
Youll likely find it easier to meet all your nutritional needs in trimesters two and three (when you dont feel like retching all day). But you can use these tips at all points in your pregnancy to ensure your baby gets the best nutrition for a healthy start in life
These recipes can help you get started in developing a nutritionally complete eating plan:
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Can You Safely Have a Vegetarian Pregnancy? Health Essentials from Cleveland Clinic - Health Essentials from Cleveland Clinic
JK Rowling faces backlash for likening transgender hormone replacement to gay conversion therapy – The Indian Express
By: Lifestyle Desk | New Delhi | Published: July 7, 2020 6:33:51 pm Rowling wrote a long tread defending herself. (Photo: JK Rowling/Facebook)
It will probably be a while for JK Rowling to extricate herself from the growing controversy she finds herself embroiled in. Recently, the Harry Potter author faced fresh heat on one of her tweets that suggested transgender hormone therapy is a variant of conversion therapy for young gay people..
It all started when a Twitter user made a claim that the author had allegedly liked a tweet that compared prescribed hormones to antidepressants. Soon, Rowling wrote a long tread defending herself and went to write, Ive ignored fake tweets attributed to me and RTed widely. Ive ignored porn tweeted at children on a thread about their art. Ive ignored death and rape threats. Im not going to ignore this. When you lie about what I believe about mental health medication and when you misrepresent the views of a trans woman for whom I feel nothing but admiration and solidarity, you cross a line.
She added, Ive written and spoken about my own mental health challenges, which include OCD, depression and anxiety. I did so recently in my essay TERF Wars. Ive taken anti-depressants in the past and they helped me. Many health professionals are concerned that young people struggling with their mental health are being shunted towards hormones and surgery when this may not be in their best interests. Many, myself included, believe we are watching a new kind of conversion therapy for young gay people, who are being set on a lifelong path of medicalisation that may result in the loss of their fertility and/or full sexual function. Adding to this, she shared links to support her tweets, giving instances. The long-term health risks of cross-sex hormones have been now been tracked over a lengthy period. These side-effects are often minimised or denied by trans activists.
Soon, people began expressing their anger. JK Rowling is now openly advocating for conversion therapy for trans kids. As a survivor of an extreme form of homebrew conversion therapy, I say *once again* without reservation that she is a danger to children, wrote one, while another said: JK Rowling comparing transitioning to conversion therapy is a great example of how conspiratorial and anti-science the TERF mindset is.
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JK Rowling faces backlash for likening transgender hormone replacement to gay conversion therapy - The Indian Express
Kanye West sparks fury saying Planned Parenthood ‘carries out the devil’s work’ – Mirror Online
Kanye West has denounced a US parenting organisation that has been promoted by his wife Kim Kardashian, as a conspiracy.
The 43-year-old rapper spoke out in his first interview since declaring his plans to run for the Presidency and hit out at Planned Parenthood.
The organisation says it provides essential health care services like STD testing and treatment, birth control, well-woman exams, cancer screening and prevention, abortion, hormone therapy and infertility services.
Kanye has denounced it as 'the devil's work' as he claims he is "following the word of the bible" despite wife Kim's support of Planned Parenthood and her pro-choice views.
Speaking to Forbes about his 2020 presidential campaign, Kanye revealed that he was running for office because he had received a message from God as the born again Christian set out some of his thoughts.
One of his main claims was that Planned Parenthood was the work of "white supremacists" which has prompted a swift response from the organisation.
Kanye said: I am pro-life because Im following the word of the bible. Planned Parenthoods have been placed inside cities by white supremacists to do the Devils work.
Planned Parenthoods Director of Black Leadership and Engagement, Nia Martin-Robinson, hit back at Kanye's remarks in a statement.
She said: "Black women are free to make our own decisions about our bodies and pregnancies, and want and deserve to have access to the best medical care available.
Any insinuation that abortion is Black genocide is offensive and infantilising.
"The real threat to Black communities safety, health, and lives stems from lack of access to quality, affordable health care, police violence and the criminalisation of reproductive health care by anti-abortion opposition.
Keeping Up With The Kardashians fans will recall that Kim was joined by her sisters Khloe and Kourtney at a Planned Parenthood clinic for a visit in 2017.
Kim publicly voiced her support at the time on Instagram, sharing a photo of them at one of the clinics, captioning it with: "My sisters and I visited Planned Parenthood recently and learned that the House of Representatives forced through a bill that strips health care coverage from millions of people and raises health care costs, including Planned Parenthood patients.
They are such an amazing place that provides so much to so many! #istandwithpp.
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Kanye West sparks fury saying Planned Parenthood 'carries out the devil's work' - Mirror Online
Health Experts Weigh In on the Real Reason You’re Always Feeling Hungry – Yahoo Canada Shine On
Ah, there it is again hunger, causing your tummy to grumble and your mind to drift away from the task in front of you. "Didn't I just have lunch an hour ago?" you might ask yourself as you make your fifth trip to peer into the fridge again. Hunger is natural and is supposed to be self-regulated; these days, everyone on talk shows and on Instagram seem to be talking about "intuitive" eating or listening to your body's needs, especially when you feel hungry. We bet you know when you've crossed a line, though, and "snacking" turns into an unintentional fourth or fifth meal. If you constantly feel hungry no matter what you're eating, it's time to think about what you're putting on the plate.
Sometimes, an unchecked increase in appetite can be explained by other health conditions or life situations (such as breast feeding), or even by medications you take. But more often, there may be other choices you're making during the day that might unintentionally add fuel to your endless appetite. Below, with the help of a holistic panel of health experts assembled by Good Housekeeping, we explore some of the reasons you may be feeling hungry all of the time and how to fix them, starting right now.
Believe it or not, sometimes our body processes thirst in the same way that it processes hangry pangs, and you could be mistaking thirst for hunger. Stefani Sassos, MS, RDN, CDN, the Good Housekeeping Institute's registered dietitian, explains that how much water you drink directly influences how "satiated" (full!) you feel during the day. "My biggest tip is not to wait until you're 'thirsty' to grab some water chances are that you're already dehydrated if you're feeling thirst or dry mouth," Sassos says, adding that most women need to consume at least 72 ounces of water each day (but that formula may depend on your size and activity level). "Set a schedule for yourself to space out your water intake throughout the day and make it a priority." Plus, upping how much water you're drinking on average may be a boon for weight loss if you're dieting or exercising, as Sassos links being properly hydrated to active metabolic rates throughout the day.
How do you know if you're actually thirsty and not truly hungry in the moment? Try drinking a glass or two of water before you decide if it's time to eat again, and wait a few minutes. "You'll be able to gauge whether you're truly hungry or just thirsty," Sassos says.
Meaning, you may be missing out on a much-needed meal (like breakfast!) when you're burning through a bunch of energy during the day or, you're mindlessly eating when you're simply bored on the couch. Comprehensive research establishing the link between hunger and physical activity is lacking, but as Sassos points out, limited research suggests that exercise may trick your body into suppressing appetite during a workout (your body temperature may have something to do with that phenomena). If you're not eating wholesome meals before or after prolonged activity cycling, running, swimming, lifting weights, as examples you may be setting yourself up for intense hunger pangs later in the day. "You need proper nutrition to help repair your muscle," Sasso says, adding that she'll actively pad her meals with nutritious picks to "complement" her workout session.
Conversely, you may be engaging in distracted or mindless eating when you're sedentary (think: on the couch, at your desk, or in the car). "If you're sedentary most of the day and not doing much, boredom can certainly entice you to eat more," Sassos says. "If you just ate and know you should feel full, but are bored and want to eat more, consider distracting yourself pick up a book, or actually get up and exercise! If I know I'm just bored and not hungry, I'll hold a plank for a minute and that craving will go away."
Fiber is that magical ingredient that makes a meal feel really filling as opposed to something that doesn't really satisfy you after you've finished eating, explains Julie Benard, M.D., a board-certified pediatric obesity medicine specialist and a pediatrician within the University of Missouri Health Care system. "A diet low in fiber can cause frequent hunger, as fiber is broken down slowly by our gastrointestinal tract, which leads to more stable blood sugar levels and therefore less feelings of hunger," she says.
You should be aiming to eat your way through 25g of fiber throughout the day, Sassos says. But you don't have to painstakingly count at first: Load up on meals that are highly fibrous, that incorporate things like avocados, beans, or most nuts as the main attraction. You should feel the results soon thereafter: "High-fiber foods may actually take longer to chew, are slower to digest, and promote satiety," Sassos says.
Dr. Benard and Sassos don't want you to believe all carbs are bad: Whole grains, fruits, and vegetables all contain naturally occurring carbohydrates, and they are definitely pillars of any healthy diet. Refined carbohydrates, however, should be enjoyed occasionally. White breads, pasta, and pastries, among many other items that are also high in saturated fats and sugar, cause a spike in insulin, a hormone that helps regulate blood sugar. "We get an initial burst of energy and satiety from these starchy and sugary treats, but then insulin causes our body to burn through that sugar quickly," Dr. Benard explains. "This leads to subsequent rapid declines in blood sugar that trigger our feelings of hunger once again."
Photo credit: Getty Images
Sugar is a carbohydrate too, and it's often the main ingredient in refined carbohydrates alongside classic desserts that you're thinking of right now. You probably are sick to death of hearing about that afternoon "sugar crash," when your blood sugar plummets after eating something very sweet, which later causes you to reach for even more food to help you get your blood sugar back up again. But did you know that repeatedly working your way through this cycle may cause lasting damage? Sugar and refined carbohydrates play into constant elevated blood sugar that can lead to insulin resistance, when your body can't use glucose from your blood for energy (a form of prediabetes), Sassos says.
"Interestingly enough, insulin shares similarities with leptin a hormone that helps to regulate appetite and weight control," she explains. "Lepin and insulin actually directly regulate each other, and in the case of insulin resistance, this will cancel out the 'appetite-control' effect and can lead to a vicious hunger cycle." Sugar is naturally found in nutritious items like fruits, but if you can identify snacks in your daily rotation that are high in added sugars or processed carbs, those are some of the first items you should cut back on.
If you're new to trying out a vegetarian or vegan diet, this could be especially true. And protein doesn't just mean red meat! It includes lean fish, poultry, and plant-based items like tofu or lentils. "A diet low in protein can also lead to frequent feelings of hunger, even though one may be consuming a higher amount of calories," Dr. Benard says.
She explains that a hormone called ghrelin is the hormone responsible for our hunger pangs at the molecular level, and is released when the stomach is empty. Our stomach is stretched in the process of eating, thus decreasing the levels of ghrelin released, but "what we're eating can determine how long our ghrelin levels stay low," Dr. Benard says. "Protein is the most effective nutrient at keeping ghrelin low for longer periods of time, especially compared to carbohydrates." Science!
Which is why you may always fall prey to a post-lunch (or dinner) snack later on. "A lot of people will tell me they're 'being good' with their nutrition up until the afternoon, where cravings hit and they just fall off the wagon," Sassos explains. "When I go to analyze their 'good' mornings, it's usually just low-calorie! Restricting yourself early in the day actually may set you up for failure as the day progresses."
There's been a lot of debate around skipping breakfast recently, and some dieters swear by restricting their meals to certain hours of the day (often referred to as intermittent fasting). Regardless of when you choose to eat your first meal of the day, it should be full of nourishing items alongside plenty of water, Sassos recommends. "Im a fan of bulking up that breakfast and lunch meal with lean protein, healthy fiber, and tons of vegetables to keep you full for hours," she says. "Eating fiber in the morning can help to control afternoon cravings, and I like to look at it as making an investment to help you have a successful day."
Feeling hungry might be a side effect of purposefully not feeding yourself because you feel that you've "lost control," says David Schlundt, PhD, an associate professor of psychology at Vanderbilt University and a member of the university's Diabetes Research and Training Center. "Food provides some temporary relief from negative emotion, but hunger is rarely the trigger for emotional eating It's a problem when people impose unrealistically strict dietary rules on themselves," he says.
For example, if you believe that you shouldn't eat breakfast because it'll make you gain weight, then you will likely feel hungry when you skip it and then break other self-imposed dietary rules. "An example might be that you believe donuts are bad, but when you're hungry and there's a donut in the break room, you pick up two when no one is looking," Schlundt explains. "This becomes a problem not because you took in calories your body was telling you to do that but because the perceived rule violation is a negative experience leading to guilt, self-blame, and abstinence violation. This is the extended loss of control that occurs as a result of your self-defined dietary violation."
This behavior can lead you to be extremely restrictive in what you eat, when you eat, or how much you eat later on, Schlundt says, all factors that can influence your appetite.
Photo credit: Mike Garten
Ah, yet another way that sleep can impact our daily lives. Not getting enough rest at night may inadvertently affect how much you're eating throughout the day, especially if you're frequently getting less than 7 hours of sleep. "Feeling sleep deprived can do a number on our will power, as we then tend to not make the best nutrition choices," Dr. Benard says, like easy ready-to-eat items containing refined carbs and sugar. "On a hormonal level, some studies also suggest that a lack of sleep may be associated with lower levels of leptin our 'feeling full' hormone and higher levels of ghrelin the hungry hormone."
These hormones may be at the heart of why sleep deprivation has been associated with excessive weight gain over a longer period, Sassos says. A landmark study published in the American Journal of Epidemiology followed 60,000 women over 16 years while recording their sleep habits and dietary functions alongside other lifestyle aspects; it noted that women who slept 5 hours or less per night had a 15% higher risk of becoming obese, and were 30% more likely to gain 30 pounds in the same time frame compared to women who slept 7 hours each night.
All to say: You should be doing everything in your power to establish better sleep hygiene, and work on creating a better-for-you bedtime routine.
"I like to categorize cravings by whether they're coming from above the neck or below the neck," Sassos explains. "Above the neck cravings are emotional, often come on suddenly, and aren't satisfied even if you do eat a full meal. They may trigger feelings of shame and guilt, and you may feel like you have no control over your food choices."
On the flip side, then, "below the neck" cravings are actually a sign of physical hunger that you shouldn't ignore, Sassos says. "These cravings build gradually, and many food options sound appealing. Once you're sensibly full, the cravings go away. Below the neck cravings aren't associated with any feelings of guilt or anger, but rather you feel satisfied or even relieved after eating that particular item or meal."
Stress has a terrible way of impacting much of our lives, including how much we eat; the flight-or-fight response associated with stress can lead to an increase in hunger later on (the Cleveland Clinic even lists hunger a side effect of stress). But more seriously, Schlundt says that a severe, sustained change in appetite is one of the main symptoms of major depressive disorder. "There are two types of people: Those who eat more when depressed, and those who lose interest in food when depressed," he adds. "Eating more when depressed may be more complicated than just increased hunger. It is probably some degree of loss of control over behavior rather than hunger alone."
If mealtimes have become an unstable part of your day and feel that it might be due to anxiety, depression, or emotional trauma, you should consider seeking out professional help. The American Psychological Association's Psychologist Locator tool can help you find a licensed therapist in your area that takes your insurance.
Underlying conditions like these can be the source of your insatiable appetite, but this is probably the least likely explanation for feeling hungry all the time. "Increased hunger can certainly be a sign of diabetes, alongside increased thirst or frequent urination," Dr. Benard says. "It also could be a sign of hyperthyroidism, which goes hand in hand with an increased heart rate, feeling jittery, or losing weight without trying There are rarely genetic changes that can lead to insatiable hunger as well."
If you feel like you've exhausted the suggestions on this list to no avail, it's time to schedule a checkup with your healthcare provider, where you can address your diet and other aspects of your hunger in depth. Your appetite may be caused by a condition that's beyond your control and could require qualified attention.
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Health Experts Weigh In on the Real Reason You're Always Feeling Hungry - Yahoo Canada Shine On
Simple hair test ‘could tell women how many eggs they have left’ – Brinkwire
A simple test of a womans hair could tell women how many eggs they have left by judging levels of a key fertility hormone, scientists say.
US and Spanish researchers found biologically relevant levels of anti-Mllerian hormone (AMH) an indicator of ovarian reserves in womens hair samples.
AMH is a hormone produced by the cells within a womans ovaries and gives an indication of her egg reserves and subsequent fertility.
The hormone is incorporated into the matrix of hair before it reaches the surface of the skin.
Levels of AMH from the hair correlated with levels from blood samples, which is currently the most common method of measuring the hormone.
But taking AHM readings from the hair would be less invasive than a blood sample and a more appropriate representation of hormone levels, according to scientists.
Testing can be done without visiting a clinic, such as by sending a hair sample through the post, which makes this type of test cheaper and available to a broader range of women.
The role of AMH as a measure of ovarian reserve in predicting response to ovarian stimulation for IVF now seems beyond question, researchers add.
Hair is a medium that can accumulate biomarkers over several weeks, while serum is an acute matrix representing only current levels, said Sarthak Sawarkar at US health tech firm MedAnswers, who presented his research online at the 36th Annual Meeting of the European Society of Human Reproduction and Embryology.
While hormone levels in blood can fluctuate rapidly in response to stimuli, hormone levels measured in hair would represent an accumulation over several weeks.
A measurement using a hair sample is more likely to reflect the average hormone levels in an individual.
AMH has become a key marker in the assessment of how women may respond to fertility treatment.
The hormone is produced by small cells surrounding each egg as it develops in the ovary.
Studies have not correlated AMH levels to a reliable chance of live birth, nor to forecasting the time of menopause.
However, AMH measurement has become an intrinsic marker in assessing how a patient will respond to ovarian stimulation for IVF as a normal responder, poor responder (with few eggs), or over-responder (with many eggs and a risk of ovarian hyperstimulation syndrome).
Currently, AMH is presently measured in serum taken from a blood sample drawn intravenously, but readings taken this way represent just a snapshot of a moment in time and are relatively invasive to complete.
To learn more about the potential of AMH readings taken from the hair, researchers collected hair and blood samples 152 women from whom hair were during hospital visits.
AMH was also measured in blood samples from the same subjects, as well as an ultrasound count of developing follicles in the ovary a method known as antral follicle count (AFC).
Biologically relevant AMH levels were successfully detected in the hair samples, which declined with patient age, as expected by the team.
AMH levels from hair strongly correlated with levels as determined by both serum in the blood and AFC.
The hair test was also able to detect a wide range of AMH levels within individuals from a similar age cohort, suggesting a greater accuracy than from a single blood sample.
Hormones accumulate in hair shafts over a period of months, while hormone levels in serum can change over the course of hours, they found, meaning the hair test may be a more reliable measurement.
Hormone levels are also assessed non-invasively, which reduces testing stress and offers a less expensive assay.
This study is very interesting as it suggests AMH can be reliably measured from hair samples as opposed to the standard approach of a blood test, Tim Child, medical director at Oxford Fertility, told the Times.
The AMH level in hair is more likely to be averaged-out over a time period rather than the more instant level in a blood sample.
The question is whether the hair AMH levels correlate to the ovarian response and therefore numbers of eggs collected during an IVF cycle this is not examined in this study.
If the correlation is poor then hair samples will be of no benefit.
If the correlation is as good as, or perhaps even better than with blood AMH, then this technique promises to further simplify the fertility treatment process for women and will be an exciting development.
The results have been presented by PhD student Sarthak Sawarkar, working in the laboratory of Professor Manel Lopez-Bejar in Barcelona, with collaborators from MedAnswers.
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Simple hair test 'could tell women how many eggs they have left' - Brinkwire
Global Bone Marrow Transplant Rejection Treatment Market Report 2020, Size, Share, Business Plan, Growth Opportunities, Top Players, Application,…
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Bellicum Pharmaceuticals, Inc.Bio-Cancer Treatment International LimitedBiogen IncBoryung Pharmaceutical Co., Ltd.Bristol-Myers Squibb CompanyCantex Pharmaceuticals, Inc.Capricor Therapeutics, Inc.Cell Source, Inc.Cell2B S.A.CellECT Bio, Inc.Cleveland BioLabs, Inc.Compugen Ltd.Cynata Therapeutics LimitedCytodyn Inc.Dompe Farmaceutici S.p.A.Dr. Falk Pharma GmbHEscape Therapeutics, Inc.F. Hoffmann-La Roche Ltd.Fate Therapeutics, Inc.Generon (Shanghai) Corporation Ltd.Gilead Sciences, Inc.GlaxoSmithKline PlcIdera Pharmaceuticals, Inc.
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Segmentation by Type:
AzathioprineAdrenocorticotropic HormoneCyclophosphamideCyclosporine AOthers
Segmentation by Application:
HospitalClinicOthers
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Global Bone Marrow Transplant Rejection Treatment Market Report 2020, Size, Share, Business Plan, Growth Opportunities, Top Players, Application,...
Infertility, and the stress thereof – Greater Kashmir
There is no greater feeling than that of being a parent. This is what most parents say when you ask them how they feel about being parents, and we fully agree with them. Because the joy of bringing life into this world is completely overwhelming. The joy of becoming parents, for couples suffering from infertility problems, is above everything in this world. For us (me and my wife) to undergo this experience was a very long journey on a tough road, full of pain, stress, worry, and tensions.
After we got married in Sept 2013, my wife was suffering from some infertility problem so we couldnt conceive naturally. It is after the 10th month of our marriage the most difficult phase of our life started when people in our neighborhood, friends and relatives stared, asking queries, especially womenfolk; as it is common in our culture people start asking Kehn Chusa, meaning if they have conceived. You hear this talk just after only a few months of marriage. The infertile couples like us face so many problems, a mental harassment. Same is the case with us. We got treatment from leading gynaecologists and infertility specialists of the valley, who prescribed every kind of test, scan, hormone therapy, laparoscopy, HSG, and loads of medicines. One day we used to visit clinic and the next day to some peer baba. On the one hand doctors looted us in lacks, on the other hand peer babas in thousands. This took a heavy toll on our bodies. It consumed us physically, mentally and psychologically. We lost our precious assets, health deteriorated, money wasted, and our valuable time consumed in it. But all in vain.
God is great. We never lost hope and our prayers were accepted. When, on one day I came across an advertisement in a newspaper about Dr. Manika Khanna from Delhi, a leading IVF Specialist. We visited for appointment to Karan Nagar, Srinagar, and after consultations we decided to accept her advice to visit Delhi for IVF Treatment. That visit changed our life for good. In our first attempt we conceived (Gaudium IVF Hospital Delhi). Manika Madam came like an angel in our life. She and her dedicated team including names like Dr. Meetu, Dr. Nikita, staff nurses like Minni sister etc. work very hard to bring happiness in childless families. I am thankful to almighty Allah who sent an angel in the form of Manika madam and her team Gaudium, for providing us life changing experience. At the same time I am thankful to dear Ishfaq Shaheen who belongs to Srinagar branch of Gaudium who guided me and all such couples like us throughout this successful journey.
At last I would like to advice all such couples, dont waste your hard earned money and your precious time. Consult some authentic specialist, and then leave it to God.
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Infertility, and the stress thereof - Greater Kashmir
COVID-19 Impact on Endometriosis Therapies Market Trends, Key Players, Overview, Competitive Breakdown and Regional Forecast by 2026 – Owned
Endometriosis Therapies Market 2020: Inclusive Insight
Los Angeles, United States, July 2020: The Endometriosis Therapies on the Move market has been garnering remarkable momentum in the recent years. The steadily escalating demand due to improving purchasing power is projected to bode well for the market. Report Hives latest publication, Titled [Endometriosis Therapies on the Move Market Research Report 2020], offers an insightful take on the drivers and restraints present in the market. It assesses the historical data pertaining to the Endometriosis Therapies on the Move market and compares it to the current market trends to give the readers a detailed analysis of the trajectory of the market. A team subject-matter experts have provided the readers a qualitative and quantitative data about the market and the various elements associated with it. Additionally, this report encompasses an accurate competitive analysis of major market players and their strategies during the projection timeline.
The research study includes the latest updates about the COVID-19 impact on the Endometriosis Therapies on the Move sector. The outbreak has broadly influenced the global economic landscape. The report contains a complete breakdown of the current situation in the ever-evolving business sector and estimates the aftereffects of the outbreak on the overall economy. Key players in this market are AbbVie, Eli Lilly, AstraZeneca, Bayer, Astellas Pharma, Meditrina Pharmaceuticals, Pfizer, Neurocrine Biosciences, Takeda Pharmaceutical
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There are 10 Chapters to deeply display the Endometriosis Therapies market:
Chapter 1, is executive summary of Endometriosis Therapies Market; Chapter 2, is definition and segment of Endometriosis Therapies; Chapter 3, to show info and data comparison of Endometriosis Therapies Players; Chapter 4, to explain the industry chain of Endometriosis Therapies; Chapter 5, to show comparison of regions and courtiers(or sub-regions); Chapter 6, to show competition and trade situation of Endometriosis Therapies Market; Chapter 7, to show comparison of applications; Chapter 8, to show comparison of types; Chapter 9, to show investment of Endometriosis Therapies Market; Chapter 10, to forecast Endometriosis Therapies market in the next years.
Global Endometriosis Therapies Market is estimated to reach xxx million USD in 2020 and projected to grow at the CAGR of xx% during 2020-2026. According to the latest report added to the online repository of Report Hive Research the Endometriosis Therapies market has witnessed an unprecedented growth till 2020. The report also emphasizes the initiatives undertaken by the companies operating in the market including product innovation, product launches, and technological development to help their organization offer more effective products in the market. It also studies notable business events, including corporate deals, mergers and acquisitions, joint ventures, partnerships, product launches, and brand promotions.
COVID-19 Impact on Endometriosis Therapies Market
This study specially analyses the impact of Covid-19 outbreak on the Endometriosis Therapies Market, covering the supply chain analysis, impact assessment to the Endometriosis Therapies Market size growth rate in several scenarios, and the measures to be undertaken by Endometriosis Therapies Market companies in response to the COVID-19 epidemic.
Competitive Landscape:
The competitive analysis of major market players is another notable feature of the Endometriosis Therapies Market industry report; it identifies direct or indirect competitors in the market.
Key parameters which define the Competitive Landscape of the Endometriosis Therapies Market:
Revenue and Market Share by Player Production and Share by Player Average Price by Player Base Distribution, Sales Area and Product Type by Player Concentration Rate Mergers & Acquisitions, Expansion Manufacturing Base
While segmentation has been provided to list down various facets of the Endometriosis Therapies market, analysis methods such as S.T.E.E.P.L.E., S.W.O.T., Regression analysis, etc. have been utilized to study the underlying factors of the market. Summarization of various aspects consisted of the report has also been encompassed.
Analysis of Global Endometriosis Therapies Market: By Type
Hormonal Contraceptives, Gonadotropin-releasing Hormone (Gn-RH) Agonists , Progestin Therapy, Aromatase Inhibitors
Analysis of Global Endometriosis Therapies Market: By Application
Hospital, Clinic, Other
Endometriosis Therapies Market: Regional analysis includes:
North America (United States, Canada and Mexico) Europe (Germany, France, UK, Russia and Italy) Asia-Pacific (China, Japan, Korea, India and Southeast Asia) South America (Brazil, Argentina, etc.) Middle East & Africa (Saudi Arabia, Egypt, Nigeria and South Africa)
Our exploration specialists acutely ascertain the significant aspects of the global Endometriosis Therapies market report. It also provides an in-depth valuation in regards to the future advancements relying on the past data and present circumstance of Endometriosis Therapies market situation. In this Endometriosis Therapies report, we have investigated the principals, players in the market, geological regions, product type, and market end-client applications. The global Endometriosis Therapies report comprises of primary and secondary data which is exemplified in the form of pie outlines, Endometriosis Therapies tables, analytical figures, and reference diagrams. The Endometriosis Therapies report is presented in an efficient way that involves basic dialect, basic Endometriosis Therapies outline, agreements, and certain facts as per solace and comprehension.
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Some of the Major Highlights of TOC covers:
1 Study Coverage1.1 Endometriosis Therapies Product Introduction1.2 Market Segments1.3 Key Endometriosis Therapies Manufacturers Covered: Ranking by Revenue1.4 Market 21.4.1 Global Endometriosis Therapies Market Size Growth Rate 21.4.2 Hormonal Contraceptives, Gonadotropin-releasing Hormone (Gn-RH) Agonists , Progestin Therapy, Aromatase Inhibitors1.5 Market 31.5.1 Global Endometriosis Therapies Market Size Growth Rate 31.5.2 Hospital, Clinic, Other1.6 Study Objectives1.7 Years Considered
2 Executive Summary2.1 Global Endometriosis Therapies Market Size, Estimates and Forecasts2.1.1 Global Endometriosis Therapies Revenue 2015-20262.1.2 Global Endometriosis Therapies Sales 2015-20262.2 Global Endometriosis Therapies, Market Size by Producing Regions: 2015 VS 2020 VS 20262.2.1 Global Endometriosis Therapies Retrospective Market Scenario in Sales by Region: 2015-20202.2.2 Global Endometriosis Therapies Retrospective Market Scenario in Revenue by Region: 2015-2020
3 Global Endometriosis Therapies Competitor Landscape by Players3.1 Endometriosis Therapies Sales by Manufacturers3.1.1 Endometriosis Therapies Sales by Manufacturers (2015-2020)3.1.2 Endometriosis Therapies Sales Market Share by Manufacturers (2015-2020)3.2 Endometriosis Therapies Revenue by Manufacturers3.2.1 Endometriosis Therapies Revenue by Manufacturers (2015-2020)3.2.2 Endometriosis Therapies Revenue Share by Manufacturers (2015-2020)3.2.3 Global Endometriosis Therapies Market Concentration Ratio (CR5 and HHI) (2015-2020)3.2.4 Global Top 10 and Top 5 Companies by Endometriosis Therapies Revenue in 20193.2.5 Global Endometriosis Therapies Market Share by Company Type (Tier 1, Tier 2 and Tier 3)3.3 Endometriosis Therapies Price by Manufacturers3.4 Endometriosis Therapies Manufacturing Base Distribution, Product Types3.4.1 Endometriosis Therapies Manufacturers Manufacturing Base Distribution, Headquarters3.4.2 Manufacturers Endometriosis Therapies Product Type3.4.3 Date of International Manufacturers Enter into Endometriosis Therapies Market3.5 Manufacturers Mergers & Acquisitions, Expansion Plans
4 Market Size 2 (2015-2026)4.1 Global Endometriosis Therapies Market Size 2 (2015-2020)4.1.1 Global Endometriosis Therapies Sales 2 (2015-2020)4.1.2 Global Endometriosis Therapies Revenue 2 (2015-2020)4.1.3 Endometriosis Therapies Average Selling Price (ASP) 2 (2015-2026)4.2 Global Endometriosis Therapies Market Size Forecast 2 (2021-2026)4.2.1 Global Endometriosis Therapies Sales Forecast 2 (2021-2026)4.2.2 Global Endometriosis Therapies Revenue Forecast 2 (2021-2026)4.2.3 Endometriosis Therapies Average Selling Price (ASP) Forecast 2 (2021-2026)4.3 Global Endometriosis Therapies Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End
5 Market Size 3 (2015-2026)5.1 Global Endometriosis Therapies Market Size 3 (2015-2020)5.1.1 Global Endometriosis Therapies Sales 3 (2015-2020)5.1.2 Global Endometriosis Therapies Revenue 3 (2015-2020)5.1.3 Endometriosis Therapies Price 3 (2015-2020)5.2 Endometriosis Therapies Market Size Forecast 3 (2021-2026)5.2.1 Global Endometriosis Therapies Sales Forecast 3 (2021-2026)5.2.2 Global Endometriosis Therapies Revenue Forecast 3 (2021-2026)5.2.3 Global Endometriosis Therapies Price Forecast 3 (2021-2026)
6 North America6.1 North America Endometriosis Therapies by Country6.1.1 North America Endometriosis Therapies Sales by Country6.1.2 North America Endometriosis Therapies Revenue by Country6.1.3 United States6.1.4 Canada6.1.5 Mexico6.2 North America Endometriosis Therapies Market Facts & Figures 26.3 North America Endometriosis Therapies Market Facts & Figures 3
7 Europe7.1 Europe Endometriosis Therapies by Country7.1.1 Europe Endometriosis Therapies Sales by Country7.1.2 Europe Endometriosis Therapies Revenue by Country7.1.3 Germany7.1.4 France7.1.5 UK7.1.6 Italy7.1.7 Russia7.2 Europe Endometriosis Therapies Market Facts & Figures 27.3 Europe Endometriosis Therapies Market Facts & Figures 3
8 Asia Pacific8.1 Asia Pacific Endometriosis Therapies by Region8.1.1 Asia Pacific Endometriosis Therapies Sales by Region8.1.2 Asia Pacific Endometriosis Therapies Revenue by Region8.1.3 China8.1.4 Japan8.1.5 South Korea8.1.6 India8.1.7 Australia8.1.8 Indonesia8.1.9 Thailand8.1.10 Malaysia8.1.11 Philippines8.1.12 Vietnam8.2 Asia Pacific Endometriosis Therapies Market Facts & Figures 28.3 Asia Pacific Endometriosis Therapies Market Facts & Figures 3
9 Latin America9.1 Latin America Endometriosis Therapies by Country9.1.1 Latin America Endometriosis Therapies Sales by Country9.1.2 Latin America Endometriosis Therapies Revenue by Country9.1.3 Brazil9.2 Central & South America Endometriosis Therapies Market Facts & Figures 29.3 Central & South America Endometriosis Therapies Market Facts & Figures 3
10 Middle East and Africa10.1 Middle East and Africa Endometriosis Therapies by Country10.1.1 Middle East and Africa Endometriosis Therapies Sales by Country10.1.2 Middle East and Africa Endometriosis Therapies Revenue by Country10.1.3 Turkey10.1.4 GCC Countries10.1.5 Egypt10.1.6 South Africa10.2 Middle East and Africa Endometriosis Therapies Market Facts & Figures 210.3 Middle East and Africa Endometriosis Therapies Market Facts & Figures 3
11 Company Profiles11.1 Company111.1.1 Company1 Corporation Information11.1.2 Company1 Description and Business Overview11.1.3 Company1 Sales, Revenue and Gross Margin (2015-2020)11.1.4 Company1 Endometriosis Therapies Products Offered11.1.5 Company1 Related Developments11.2 Company211.2.1 Company2 Corporation Information11.2.2 Company2 Description and Business Overview11.2.3 Company2 Sales, Revenue and Gross Margin (2015-2020)11.2.4 Company2 Endometriosis Therapies Products Offered11.2.5 Company2 Related Developments11.3 Company311.3.1 Company3 Corporation Information11.3.2 Company3 Description and Business Overview11.3.3 Company3 Sales, Revenue and Gross Margin (2015-2020)11.3.4 Company3 Endometriosis Therapies Products Offered11.3.5 Company3 Related Developments11.4 Company411.4.1 Company4 Corporation Information11.4.2 Company4 Description and Business Overview11.4.3 Company4 Sales, Revenue and Gross Margin (2015-2020)11.4.4 Company4 Endometriosis Therapies Products Offered11.4.5 Company4 Related Developments
12 Future Forecast by Regions (Countries) (2021-2026)12.1 Endometriosis Therapies Market Estimates and Projections by Region12.1.1 Global Endometriosis Therapies Sales Forecast by Regions 2021-202612.1.2 Global Endometriosis Therapies Revenue Forecast by Regions 2021-202612.2 North America Endometriosis Therapies Market Size Forecast (2021-2026)12.2.1 North America: Endometriosis Therapies Sales Forecast (2021-2026)12.2.2 North America: Endometriosis Therapies Revenue Forecast (2021-2026)12.2.3 North America: Endometriosis Therapies Market Size Forecast by Country (2021-2026)12.3 Europe Endometriosis Therapies Market Size Forecast (2021-2026)12.3.1 Europe: Endometriosis Therapies Sales Forecast (2021-2026)12.3.2 Europe: Endometriosis Therapies Revenue Forecast (2021-2026)12.3.3 Europe: Endometriosis Therapies Market Size Forecast by Country (2021-2026)12.4 Asia Pacific Endometriosis Therapies Market Size Forecast (2021-2026)12.4.1 Asia Pacific: Endometriosis Therapies Sales Forecast (2021-2026)12.4.2 Asia Pacific: Endometriosis Therapies Revenue Forecast (2021-2026)12.4.3 Asia Pacific: Endometriosis Therapies Market Size Forecast by Region (2021-2026)12.5 Latin America Endometriosis Therapies Market Size Forecast (2021-2026)12.5.1 Latin America: Endometriosis Therapies Sales Forecast (2021-2026)12.5.2 Latin America: Endometriosis Therapies Revenue Forecast (2021-2026)12.5.3 Latin America: Endometriosis Therapies Market Size Forecast by Country (2021-2026)12.6 Middle East and Africa Endometriosis Therapies Market Size Forecast (2021-2026)12.6.1 Middle East and Africa: Endometriosis Therapies Sales Forecast (2021-2026)12.6.2 Middle East and Africa: Endometriosis Therapies Revenue Forecast (2021-2026)12.6.3 Middle East and Africa: Endometriosis Therapies Market Size Forecast by Country (2021-2026)
13 Market Opportunities, Challenges, Risks and Influences Factors Analysis13.1 Market Opportunities and Drivers13.2 Market Challenges13.3 Market Risks/Restraints13.4 Porters Five Forces Analysis13.5 Primary Interviews with Key Endometriosis Therapies Players (Opinion Leaders)
14 Value Chain and Sales Channels Analysis14.1 Value Chain Analysis14.2 Endometriosis Therapies Customers14.3 Sales Channels Analysis14.3.1 Sales Channels14.3.2 Distributors
15 Research Findings and Conclusion
16 Appendix16.1 Research Methodology16.1.1 Methodology/Research Approach16.1.2 Data Source16.2 Author Details16.3 Disclaimer
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Death in Cellectis off-the-shelf CAR-T trial triggers FDA hold – FierceBiotech
The FDA has put a phase 1 trial of Cellectis off-the-shelf CAR-T therapy UCARTCS1A on clinical hold after learning of a death in the study. Cellectis said the multiple myeloma patient suffered a cardiac arrest after receiving the highest dose of the anti-CS1 allogeneic CAR-T.
Before joining the Cellectis trial, the patient underwent multiple prior lines of treatment, including with autologous CAR-T cells, without success. In the Cellectis trial, the patient was the first person to receive the higher, 3 million cells per kilogram dose of UCARTCS1A. The patient experienced cytokine release syndrome of undisclosed severity and died of a cardiac arrest 25 days after treatment.
The FDA has placed the trial on clinical hold while Cellectis evaluates the case. According to Cellectis, plans were already afoot to expand the lower, 1 million cells per kilogram dose cohort before the patient death. Preliminary data suggest 1 million cells per kilogram may be the phase 2 dose.
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There are signs the lower dose also has some safety issues. Analysts at Jefferies think investigators gave one or more of the three low-dose patients rituximab to activate the CAR-T safety switch. Work is underway to update the phase 1 protocol to mitigate the potential risks posed by UCARTCS1A.
The modifications may include increased monitoring of parameters related to cytokines. The Jefferies analysts think Cellectis should exclude patients previously treated with anti-BCMA CAR-Ts, such as Johnson & Johnsons JNJ-4528, due to risks related to back-to-back rounds of lymphodepletion, but note that management at the biotech think it is important to enroll that pre-treated population.
In a follow-up note, the analysts identified the use of cyclophosphamide, a chemotherapy drug, in the lymphodepletion regimen as a potential cause of the cardiac arrest. The argument is based on a 2017 paper that describes the case of a patient who died of acute heart failure after receiving a high dose of cyclophosphamide as part of an autologous stem cell transplantation treatment.
Many patients receive cyclophosphamide without suffering cardiac complications, but the analysts see reasons to think the subject enrolled in the Cellectis trial may have been at higher risk. Notably, prior exposure may increase risk, according to the analysts, suggesting the patients previous round of lymphodepletion may have been a factor.
Even if cyclophosphamide is at the heart of the problem, the analysts still think the UCARTCS1A dose is a contributing factor. With patients in the low-dose cohort also experiencing adverse events, the analysts see dosing at below 1 million cells per kilogram as one possible outcome of the situation.
Shares in Cellectis fell 13% in after-hours trading following news of the clinical hold. The value of Allogene Therapeutics, which licensed CAR-T assets that originated at Cellectis, held steady, likely reflecting a belief that the safety issue is limited to UCARTCS1A.
The Jefferies analysts see little or no read-through to other allogeneic programs, noting that the UCARTCS1A trial started at a higher dose than Cellectis two other clinical programs and that Allogene is testing several lymphodepletion regimens. The FDA placed a clinical trial of another Cellectis CAR-T, UCART123, on hold in 2017 after a patient died, but cleared it to resume months later.
Originally posted here:
Death in Cellectis off-the-shelf CAR-T trial triggers FDA hold - FierceBiotech
Could induced pluripotent stem cells be the breakthrough genetics has been waiting for? – The New Economy
Embryonic stem cells. The ethical issues associated with stem cell research could be resolved through the use of induced pluripotent stem cells, which are derived from fully committed and differentiated cells of the adult body
The almost miraculous benefits that stem cells may one day deliver have long been speculated on. Capable of becoming different types of cells, they offer huge promise in terms of transplant and regenerative medicine. It is, however, also a medical field that urges caution one that must constantly battle exaggeration. If stem cells do in fact hold the potential to reverse the ageing process, for example, then such breakthroughs remain many years away.
Recently, though, the field has had cause for excitement. In 2006, Japanese researcher Shinya Yamanaka discovered that mature cells could be reprogrammed to become pluripotent, meaning they can give rise to any cell type of the body. In 2012, the discovery of these induced pluripotent stem cells (iPSCs) saw Yamanaka and British biologist John Gurdon awarded the Nobel Prize in Physiology or Medicine. Since then, there has been much talk regarding the potential iPSCs possess, not only for the world of medicine, but for society more generally, too.
A big stepHistorically, one of the major hurdles preventing further research into stem cells has been an ethical one. Until the discovery of iPSCs, embryonic stem cells (ESCs) represented the predominant area of research, with cells being taken from preimplantation human embryos. This process, however, involves the destruction of the embryo and, therefore, prevents the development of human life. Due to differences in opinion over when life is said to begin during embryonic development, stem cell researchers face an ethical quandary.
The promise of significant health benefits and new revenue streams has led some clinics to offer unproven stem cell treatments to individuals
With iPSCs, though, no such dilemmas exist. IPSCs are almost identical to ESCs but are derived from fully committed and differentiated cells of the adult body, such as a skin cell. Like ESCs, iPSCs are pluripotent and, as they are stem cells, can self-renew and differentiate, remaining indefinitely propagated and retaining the ability to give rise to any human cell type over time.
One important distinction to make is that both ESCs and iPSCs do not exist in nature, Vittorio Sebastiano, Assistant Professor (Research) of Obstetrics and Gynaecology (Reproductive and Stem Cell Biology) at Stanford Universitys Institute for Stem Cell Biology and Regenerative Medicine, told The New Economy. They are both beautiful laboratory artefacts. This means that at any stage of development, you cannot find ESCs or iPSCs in the developing embryo, foetus or even in the postnatal or adult body. Both ESCs and iPSCs can only be established and propagated in the test tube.
The reason neither ESCs nor iPSCs can be found in the body is that they harbour the potential to be very dangerous. As Sebastiano explained, these cells could spontaneously differentiate into tumorigenic masses because of their intrinsic ability to give rise to any cell type of the body. Over many years of research, scientists have learned how to isolate parts of the embryo (in the case of ESCs) and apply certain culture conditions that can lock cells in their proliferative and stem conditions. The same is true for iPSCs.
To create iPSCs, scientists take adult cells and exogenously provide a cocktail of embryonic factors, known as Yamanaka factors, for a period of two to three weeks. If the expression of such factors is sustained for long enough, they can reset the programme of the adult cells and establish an embryonic-like programme.
Turning back the clockThere is already a significant body of research dedicated to how stem cells can be used to treat disease. For example, mesenchymal stem cells (usually taken from adult bone marrow) have been deployed to treat bone fractures or as treatments for autoimmune diseases. It is hoped that iPSCs could hold the key for many more treatments.
Global stem cell market:25.5%Expected compound annual growth rate (2018-24)$467bnExpected market value (2024)
IPSCs are currently utilised to model diseases in vitro for drug screening and to develop therapies that one day will be implemented in people, Sebastiano explained. Given their ability to differentiate into any cell type, iPSCs can be used to differentiate into, for example, neurons or cardiac cells, and study specific diseases. In addition, once differentiated they can be used to test drugs on the relevant cell type. Some groups and companies are developing platforms for cell therapy, and I am personally involved in two projects that will soon reach the clinical stage.
Perhaps the most exciting prospects draw on iPSCs regenerative properties. Over time, cells age for a variety of reasons namely, increased oxidative stress, inflammation and exposure to pollutants or sunlight, among others. All these inputs lead to an accumulation of epigenetic mistakes those that relate to gene expression rather than an alteration of the genetic code itself in the cells, which, over time, results in the aberrant expression of genes, dysfunctionality at different levels, reduced mitochondrial activity, senescence and more besides. Although the epigenetic changes that occur with time may not be the primary cause of ageing, the epigenetic landscape ultimately affects and controls cell functionality.
What we have shown is that, if instead of being expressed for two weeks we express the reprogramming factors for a very short time, then we see that the cells rejuvenate without changing their identity, Sebastiano said. In other words, if you take a skin cell and express the reprogramming genes for two to four days, what you get is a younger skin cell.
By reprogramming a cell into an iPSC, you end up with an embryonic-like cell the reprogramming erases any epigenetic errors. If expressed long enough, it erases the epigenetic information of cell identity, leaving embryonic-like cells that are also young.
Slow and steadyAs with any scientific advancement, financial matters are key. According to Market Research Engine, the global stem cell market is expected to grow at a compound annual growth rate of 25.5 percent between 2018 and 2024, eventually reaching a market value of $467bn. The emergence of iPSCs has played a significant role in shaping these predictions, with major bioscience players, such as Australias Mesoblast and the US Celgene, working on treatments involving this particular type of stem cell.
The business potential around stem cell research is huge, Sebastiano told The New Economy. [Particularly] when it comes to developing cell banks for which we have detailed genetic information and, for example, studying how different drugs are toxic or not on certain genetic backgrounds, or when specific susceptibility mutations are present.
Unfortunately, even as the business cases for iPSC treatments increase, a certain degree of caution must be maintained. The promise of significant health benefits and new revenue streams has led some clinics to offer unproven stem cell treatments to individuals. There have been numerous reports of complications emerging, including the formation of a tumour following experimental stem cell treatment in one particular patient, as recorded in the Canadian Medical Association Journal last year. Such failures risk setting the field back years.
The challenge for researchers now will be one of balance. The potential of iPSCs is huge both in terms of medical progress and business development but can easily be undermined by misuse. Medical advancements, particularly ones as profound as those associated with iPSCs, simply cannot be rushed.
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Could induced pluripotent stem cells be the breakthrough genetics has been waiting for? - The New Economy
New technology May Raise the quality of stem cells Found in regenerative medicine – Microbioz India
Stem cells have been holding great promise for regenerative medicine for ages. In the last decade, many studies have revealed this form of cell, which in Spanish is calledmother cell due to its ability to contribute to various different cell types, may be applied in regenerative medicine to diseases such as muscle and nervous system disorders, among others.
Scientists and stem cell leaders Sir John B. Gurdon and Shinya Yamanaka received the Nobel Prize in Physiology and Medicine in 2012 for this idea.
However, one of the key constraints in the application of these herbal remedies is the caliber of the stem cells that may be made in the lab, which impedes their use for curative purposes.
Currently, a team in the Cell Division and Cancer Group of the Spanish National Cancer Research Centre (CNIO), headed by researcher Marcos Malumbres, has recently developed a fresh, easy and fast technology that enhances in vitro and in vivo the possibility of stem cells to differentiate into adult cells. The study results will be released this week in The EMBO Journal.
In recent years, several protocols have been proposed to obtain reprogrammed stem cells in the laboratory from adult cells, but very few to improve the cells we already have.The method we developed is able to significantly increase the quality of stem cells obtained by any other protocol, thus favouring the efficiency of the production of specialised cell types.Mara Salazar-Roa, Study First Author and Researcher, Centro Nacional de Investigaciones Oncolgicas
Roa is likewise the co-corresponding author of this analysis.
Within this study, the researchers identified an RNA sequence, called microRNA 203, that can be found at the earliest embryonic stages before the embryo implants in the uterus and when stem cells have their highest ability to generate all the different cells.When they added this molecule to stem cells from the laboratory, they discovered that the cells ability to convert into other cell types improved appreciably.
To corroborate them, they used stem cells of both human and murine origin, and of genetically altered mice. The results were so spectacular, both in mouse cells and in human cells
Application of the microRNA for just 5 days boosts the potential of stem cells in most situations we tested and improves their ability to become other specialised cells, even months after being connected with the microRNA. Says Salazar-Roa.
According to the research, cells modified by this new protocol are more efficient in generating functional cardiac cells, opening the doorway to a better generation of different cell types essential for the cure of degenerative disorders.
Malumbres, mind of the CNIO Cell and Cancer Division Group, states:To deliver this asset to the clinic, cooperation with labs or companies that are looking to exploit that technology is now essential in each particular case.
In this circumstance, Salazar-Roa recently participated, in close collaboration with all the CNIOs Innovation group, in prestigious creation programs like IDEA2 International of the Massachusetts Institute of Technology (MIT) and also CaixaImpulse of thisLa Caixa Foundation, where they also obtained funding to start the maturation of the technology.
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New technology May Raise the quality of stem cells Found in regenerative medicine - Microbioz India
Expanded Access Protocol Initiated for Compassionate Use of Remestemcel-L in Children With Multisystem Inflammatory Syndrome Associated With COVID-19…
NEW YORK, July 06, 2020 (GLOBE NEWSWIRE) -- Mesoblast Limited (Nasdaq:MESO; ASX:MSB) today announced that an expanded access protocol (EAP) has been initiated in the United States for compassionate use of its allogeneic mesenchymal stem cell (MSC) product candidate remestemcel-L in the treatment of COVID-19 infected children with cardiovascular and other complications of multisystem inflammatory syndrome (MIS-C). Patients aged between two months and 17 years may receive one or two doses of remestemcel-L within five days of referral under the EAP.
The protocol was filed with the United States Food and Drug Administration (FDA) and provides physicians with access to remestemcel-L for an intermediate-size patient population1 under Mesoblast’s existing Investigational New Drug (IND) application. According to the FDA, expanded access is a potential pathway for a patient with an immediately life-threatening condition or serious disease or condition to gain access to an investigational medical product for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
MIS-C is a life-threatening complication of COVID-19 in otherwise healthy children and adolescents that includes massive simultaneous inflammation of multiple critical organs and their vasculature. In approximately 50% of cases this inflammation is associated with significant cardiovascular complications that directly involve heart muscle and may result in decreased cardiac function. In addition, the virus can result in dilation of coronary arteries with unknown future consequences. Recent articles from Europe and the United States have described this disease in detail.2-5
Mesoblast Chief Medical Officer Dr Fred Grossman said: The extensive body of safety and efficacy data generated to date using remestemcel-L in children with graft versus host disease suggest that our cellular therapy could provide a clinically important therapeutic benefit in MIS-C patients, especially if the heart is involved as a target organ for inflammation. Use of remestemcel-L in children with COVID-19 builds on and extends the potential application of this cell therapy in COVID-19 cytokine storm beyond the most severe adults with acute respiratory distress syndrome.”
Remestemcel-L Remestemcel-L is an investigational therapy comprising culture-expanded mesenchymal stem cells derived from the bone marrow of an unrelated donor and is administered in a series of intravenous infusions. Remestemcel-L is believed to have immunomodulatory properties to counteract the inflammatory processes that are implicated in several diseases by down-regulating the production of pro-inflammatory cytokines, increasing production of anti-inflammatory cytokines, and enabling recruitment of naturally occurring anti-inflammatory cells to involved tissues.
1.www.clinicaltrials.gov; NCT04456439 2.Lancet2020; May 7. DOI: https://doi.org/10.1016/S0140-6736(20)31094-1 3.Lancet. 2020; (May 13) https://doi.org/10.1016/S0140-6736(20)31103-X 4.https://www.nejm.org/doi/full/10.1056/NEJMoa2021756 5.https://www.nejm.org/doi/full/10.1056/NEJMoa2021680
About Mesoblast Mesoblast Limited (Nasdaq:MESO; ASX:MSB) is a world leader in developing allogeneic (off-the-shelf) cellular medicines. The Company has leveraged its proprietary mesenchymal lineage cell therapy technology platform to establish a broad portfolio of commercial products and late-stage product candidates. Mesoblast has a strong and extensive global intellectual property (IP) portfolio with protection extending through to at least 2040 in all major markets. The Company’s proprietary manufacturing processes yield industrial-scale, cryopreserved, off-the-shelf, cellular medicines. These cell therapies, with defined pharmaceutical release criteria, are planned to be readily available to patients worldwide.
Mesoblast’s Biologics License Application to seek approval of its product candidate RYONCIL (remestemcel-L) for pediatric steroid-refractory acute graft versus host disease (acute GVHD) has been accepted for priority review by the United States Food and Drug Administration (FDA), and if approved, product launch in the United States is expected in 2020. Remestemcel-L is also being developed for other inflammatory diseases in children and adults including moderate to severe acute respiratory distress syndrome. Mesoblast is completing Phase 3 trials for its product candidates for advanced heart failure and chronic low back pain. Two products have been commercialized in Japan and Europe by Mesoblast’s licensees, and the Company has established commercial partnerships in Europe and China for certain Phase 3 assets.
Mesoblast has locations in Australia, the United States and Singapore and is listed on the Australian Securities Exchange (MSB) and on the Nasdaq (MESO). For more information, please see http://www.mesoblast.com, LinkedIn: Mesoblast Limited and Twitter: @Mesoblast
Forward-Looking Statements This announcement includes forward-looking statements that relate to future events or our future financial performance and involve known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance or achievements to differ materially from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. We make such forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and other federal securities laws. Forward-looking statements should not be read as a guarantee of future performance or results, and actual results may differ from the results anticipated in these forward-looking statements, and the differences may be material and adverse. Forward- looking statements include, but are not limited to, statements about: the timing, progress and results of Mesoblast’s preclinical and clinical studies; Mesoblast’s ability to advance product candidates into, enroll and successfully complete, clinical studies; the timing or likelihood of regulatory filings and approvals; and the pricing and reimbursement of Mesoblast’s product candidates, if approved; Mesoblast’s ability to establish and maintain intellectual property on its product candidates and Mesoblast’s ability to successfully defend these in cases of alleged infringement. You should read this press release together with our risk factors, in our most recently filed reports with the SEC or on our website. Uncertainties and risks that may cause Mesoblast’s actual results, performance or achievements to be materially different from those which may be expressed or implied by such statements, and accordingly, you should not place undue reliance on these forward-looking statements. We do not undertake any obligations to publicly update or revise any forward-looking statements, whether as a result of new information, future developments or otherwise.
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Expanded Access Protocol Initiated for Compassionate Use of Remestemcel-L in Children With Multisystem Inflammatory Syndrome Associated With COVID-19...
Global Hereditary Genetic Testing Market: Focus on Product, Sample, Technology, Genetic Testing Type, Application Area, Country Data (16 Countries),…
New York, July 08, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Global Hereditary Genetic Testing Market: Focus on Product, Sample, Technology, Genetic Testing Type, Application Area, Country Data (16 Countries), and Competitive Landscape - Analysis and Forecast, 2020-2030" - https://www.reportlinker.com/p05930381/?utm_source=GNW
Product Type:Kits, Consumables, and Services Sample Type: Tumor Tissue, Blood, Saliva, Bone Marrow Technology: Next Generation Sequencing, Polymerase Chain Reaction,Immunohistochemistry, In-situ Hybridization, Microarray Techniques Oncology Genetic Testing: Breast, Colorectal,Prostate, Lung, Melanoma Cardiology Genetic Testing: Cardiomyopathy,Aortopathy, Arrythmia Neurology Genetic Testing: Epilepsy, Neurodegenerative Disorders, Neuromuscular Disorders Other Genetic Testing: Newborn Screening, NIPT, Rare Disease Testing, Direct to Consumer Testing Application Area: Academia and Research Centers, Clinical Diagnostics, Drug Discovery, Monitoring and Screening
Regional Segmentation North America U.S., Canada Europe Germany, France, Italy, U.K., Spain, Russia, Netherlands Asia-Pacific Japan, China, India, Australia, Singapore Latin America Brazil, Mexico Rest-of-the-World Kingdom of Saudi Arabia (K.S.A.), U.A.E., Palestine, Algeria
Cross Segmentation North America Genetic Testing Type (Oncology Genetic Testing, Cardiology Genetic Testing, Neurology Genetic Testing, Newborn Screening, NIPT, Rare Disease Testing, Direct to Consumer Testing Europe Genetic Testing Type (Oncology Genetic Testing, Cardiology Genetic Testing, Neurology Genetic Testing, Newborn Screening, NIPT, Rare Disease Testing, Direct to Consumer Testing Asia-Pacific - Genetic Testing Type (Oncology Genetic Testing, Cardiology Genetic Testing, Neurology Genetic Testing, Newborn Screening, NIPT, Rare Disease Testing, Direct to Consumer Testing Latin America Genetic Testing Type (Oncology Genetic Testing, Cardiology Genetic Testing, Neurology Genetic Testing, Newborn Screening, NIPT, Rare Disease Testing, Direct to Consumer Testing Rest-of-the-World Genetic Testing Type (Oncology Genetic Testing, Cardiology Genetic Testing, Neurology Genetic Testing, Newborn Screening, NIPT, Rare Disease Testing, Direct to Consumer Testing
Growth Drivers Rising Prevalence of Genetic Disorders Increasing Prevalence of Various Types of Cancer, Globally Increasing Research Funding in the Field of Genomics
Market Challenges Expensive Sequencing Procedures and Their Applications in Medical Treatments High Capital Requirement Hampering the Expansion of Global Reach Stringent Regulatory Standards
Market Opportunities Technological Advancements for Exome Sequencing Rise of Direct-to-Consumer (DTC) Testing Services Massive Scope for Adoption of NGS-Based in Emerging Nations
Key Companies ProfiledAgilent Technologies, Inc., Ambry Genetics, Beijing Genomics Institute (BGI), CENTOGENE AG, Eurofins Scientific SE, F. Hoffmann-La Roche Ltd, Inc. Illumina, Inc. , Laboratory Corporation of America Holdings, Myriad Genetics, Inc., PerkinElmer, Inc., Quest Diagnostics Incorporated, Thermo Fisher Scientific Inc.
Key Questions Answered in this Report: What are the possible long-term and short-term impacts of hereditary genetic testing on the human health continuum? What are the major market drivers, challenges, and opportunities in the hereditary genetic testing? What are the key development strategies which are being implemented by the major players in order to sustain in the competitive market? What are the key regulatory implications in the developed and developing regions for the global hereditary genetic testing market? How are service-based companies impacting the growth of the global hereditary genetic testing industry and further shaping up future trends? How each segment of the market is expected to grow during the forecast period from 2020 to 2030? Who are the leading players with significant offerings to the global hereditary genetic testing market? What is the expected market dominance for each of these leading players? Which companies are anticipated to be highly disruptive in the future, and why? What are the needs that are yet to be met by the global hereditary genetic testing market with respect to the application area? What are the dynamics of various application areas and countries are impacting the global hereditary genetic testing market? What are the new market opportunities of various technologies influencing the growth of the global hereditary genetic testing market?
Market OverviewThe hereditary genetic testing has grown significantly since the technology was first commercialized, but it is important to quantify that growth and describe future trends.The genome testing industry is proliferating, and its growth is expected to continue at its torrid pace.
However, there are significant challenges that may dampen future growth if not addressed.
Our healthcare experts have found hereditary genetic testing to be one of the most rapidly evolving technologies, and the global market for hereditary genetic testing is predicted to grow at a CAGR of 13.59% over the forecast period of 2020-2030.
The unmet clinical needs for better tools to predict, diagnose, treat, and monitor disease are acting as significant factors driving the growth of sequencing industry. Other factors driving the growth include the increased understanding of the molecular basis of disease, patient demand, industry investment, and regulations that allow marketing of tests without FDA approval.
Despite rapid advanced sequencing industry growth, there are several key issues that are needed to be addressed to facilitate future growth.The relatively high total costs of delivering sequencing test results compared with other technology platforms, and limited coverage by payers, are the key challenges to the growth of this industry.
Whole genome and exome sequencing remain relatively costly requiring initial equipment investment, specialized workforce requirements, and time-intensive variant interpretation.
Within the research report, the market is segmented on the basis of oncology genetic testing, cardiology genetic testing, neurology genetic testing, product, sample, application area, and region. Each of these segments covers the snapshot of the market over the projected years, the inclination of the market revenue, underlying patterns, and trends by using analytics on the primary and secondary data obtained.
Competitive LandscapeThe exponential rise in the application of next generation sequencing on the global level has created a buzz among companies to invest in the products and services of whole genome and exome sequencing. Due to the diverse product portfolio and intense market penetration, whole genome and exome has been a pioneer in this field and been a significant competitor in this market.
On the basis of region, North America holds the largest share, due to improved healthcare infrastructure, rise in per capita income, and improvised reimbursement policies in the region. Apart from this, Latin America and the Asia-Pacific region are anticipated to grow at the fastest CAGR during the forecast period.
Countries Covered North America U.S. Canada Europe Germany France Italy U.K. Spain Russia Netherlands Rest-of-Europe Asia-Pacific China Japan India Australia Singapore Rest-of-APAC Latin America Brazil Mexico Rest-of-Latin America Rest-of-the-World (RoW)Read the full report: https://www.reportlinker.com/p05930381/?utm_source=GNW
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Global Hereditary Genetic Testing Market: Focus on Product, Sample, Technology, Genetic Testing Type, Application Area, Country Data (16 Countries),...
Pre-Pregnancy Genetic Testing Expected to Witness a Fast-paced Growth Over the Forecast Period 2016 2026 Bulletin Line – Bulletin Line
A new intelligence report Pre-Pregnancy Genetic Testing Market has been recently Added into Global Market Research collection of top-line market research reports. Global Pre-Pregnancy Genetic Testing Market report is a meticulous comprehensive analysis of this market that provides access to direct first-hand insights on the growth trail of market in near term and long term. On the basis of factual advice sourced from authentic industry pros and extensive main industry research, the report provides insights about the historical growth pattern of Pre-Pregnancy Genetic Testing Market and current market situation. It then provides short- and long-term market development projections.
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Competitive companies And manufacturers in global market
Key Players
Some of the key market players for genetic testing market are Sequenom Laboratories, Illumina, Inc, Natera, Inc, Ariosa Diagnostics, Inc, BGI Health, Natera and LifeCodexx.
The research report presents a comprehensive assessment of the market and contains thoughtful insights, facts, historical data, and statistically supported and industry-validated market data. It also contains projections using a suitable set of assumptions and methodologies. The research report provides analysis and information according to categories such as market segments, geographies, types, technology and applications.
The report covers exhaustive analysis on:
Regional analysis includes:
North America (U.S., Canada)
Latin America (Mexico. Brazil)
Western Europe (Germany, Italy, France, U.K, Spain, Nordic countries, Belgium, Netherlands, Luxembourg)
Eastern Europe (Poland, Russia)
Asia Pacific (China, India, ASEAN, Australia & New Zealand)
Japan
Middle East and Africa (GCC, S. Africa, N. Africa)
The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain. The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.
Report Highlights:
Detailed overview of parent market
Changing market dynamics in the industry
In-depth market segmentation
Historical, current and projected market size in terms of volume and value
Recent industry trends and developments
Competitive landscape
Strategies of key players and products offered
Potential and niche segments, geographical regions exhibiting promising growth
A neutral perspective on market performance
Must-have information for market players to sustain and enhance their market footprint.
NOTE All statements of fact, opinion, or analysis expressed in reports are those of the respective analysts. They do not necessarily reflect formal positions or views of Future Market Insights.
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Opportunity assessment Provided in the Pre-Pregnancy Genetic Testing Market report Is important concerning understanding the profitable regions of investment, which are the technical insights for major market players, suppliers, vendors, and other stakeholders in Pre-Pregnancy Genetic Testing Market.
In-depth global Pre-Pregnancy Genetic Testing Market taxonomy presented in this Report offers detailed insights about each of the market sections and their sub-segments, which are categorized based on par various parameters. An exhaustive regional evaluation of global Pre-Pregnancy Genetic Testing Market divides international market landscape into essential geographies.
Regional outlook and country-wise evaluation of Pre-Pregnancy Genetic Testing Market Allows for the evaluation of multi-faceted performance of market in all the crucial markets. This advice plans to provide a wider scope of report to readers and identify the most relevant profitable areas in global market place.
Key Regions and Countries Covered in Global Pre-Pregnancy Genetic Testing Market Report-
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Pan-Cancer Consortium Moves to Clarify and Promote Consistent Use of Common Terms for Biomarker and Germline Genetic Testing – BioSpace
WASHINGTON, July 7, 2020 /PRNewswire/ --A LUNGevity Foundation-led consortium of 41 leading patient advocacy organizations, professional societies, and industry partners has published a white paper detailing recommendations for the use of testing terminology in precision medicine for patient education throughout the cancer community. Use of consistent language will significantly improve patient awareness and understanding of potentially lifesaving testing options available for both new cancer diagnoses and progression or recurrence of disease.
Research shows that despite widespread acceptance of the importance of testing, actual testing rates lag far behind best-practice recommendations for both biomarker testing for somatic (acquired) mutations and other biomarkers, and for germline genetic testing for identifying germline (inherited) mutations (also known as variants). Analysis by The Consistent Testing Terminology Working Group (Working Group) indicates that language disparity is a primary obstacle to patient communication with providers about testing for their specific cancer type. Further, development of consistent language can increase patient understanding and communication, facilitate shared decision making, support value-based care, and assure concordance in policy development.
The Working Group is a consortium of 20 cancer patient advocacy groups representing solid tumor and hematologic malignancies, three professional societies, and 18 pharmaceutical and diagnostic companies and testing laboratories. Over the course of many years, multiple activities, led by numerous individual patient advocacy organizations and professional societies, have developed the groundwork for this effort. The Working Group has launched a multi-faceted dissemination and communications effort to ensure that its recommendations and supporting materials are widely available among all key stakeholders within the cancer ecosystem, including providers, patient advocacy organizations, guidelines agencies, payers, and policymakers.
In developing its recommendations, the Working Group, first convened in 2019 by LUNGevity Foundation, identified 33 terms related to biomarker, genetic, and genomic testing that were being used in patient education and clinical care within the different cancer communities. In many cases, multiple terms were used to describe the same test. Various testing modalities, the source of testing samples, and the multiplicity of gene mutations currently identifiable by testing were contributing factors in this often-confusing overlap.
In the final analysis, three umbrella descriptor terms emerged as recommendations from the Working Group's milestone exploration: "Biomarker testing"was selected as the preferred term for tests that identify characteristics, targetable findings, or other test results originating from malignant tissue and blood; "genetic testing for an inherited mutation" and "genetic testing for inherited cancer risk" were selected as consensus terms for tests used to identify germline (inherited) mutations.
"Far too many patients across all cancer types are still missing out on essential tests for biomarkers and inherited mutations indicating cancer risk," said Michelle Shiller, DO, AP/CP, MGP, Co-Medical Director of Genetics at Baylor Sammons Cancer Center and Staff Pathologist at Baylor University Medical Center. "With rates of biomarker testing and genetic testing for an inherited mutation at sub-optimal levels for numerous patient populations, patients are not benefiting from biomarker-directed care or not learning about their inherited cancer risk. Confusion around testing terms is a driving factor in this undertesting and ultimately has a detrimental impact on patient care."
Adds Nikki Martin, Director of Precision Medicine Initiatives at LUNGevity Foundation, "When someone is diagnosed with cancer, they're swept into a whirlwind of bewildering words and complex, pressing decisions. Our Working Group's goal is to help calm that storm of confusion with clear and consistent language that facilitates communication and medical decision-making. A unified voice and message from providers, industry, and the patient advocacy community about testing is absolutely vital to optimal cancer care."
An abstract on the Working Group's recommendations was published in May 2020 as part of the American Society of Clinical Oncology (ASCO) Annual Meeting Virtual Library.
The White Paper can be viewed in its entirety atwww.CommonCancerTestingTerminology.org.
Working Groupparticipating organizations include:
Patient Advocacy: CancerCare; Cancer Support Community;The CholangiocarcinomaFoundation;Clearity Foundation; Colorectal Cancer Alliance; Fight CRC; FORCE(Facing Our Risk of Cancer Empowered); International Cancer Advocacy Network; Leukemia & Lymphoma Society; The Life Raft Group; Lymphoma Research Foundation; Living Beyond Breast Cancer; Lung Cancer Action Network (LungCan); LUNGevity Foundation; National Lung Cancer Roundtable(American Cancer Society); PanCAN; Personalized Medicine Coalition; Prostate Cancer Foundation; Ovarian Cancer Research Alliance (OCRA); Sharsheret(The Jewish Breast & Ovarian Cancer Community);and Susan G. Komen.
Professional Societies: Association of Community Cancer Centers(ACCC);Association for Molecular Pathology(AMP); and National Society of Genetic Counselors(NSGC).
Industry Partners: Abbvie; Amgen;AstraZeneca; Blueprint Medicines; Boehringer Ingelheim; Bristol-Myers Squibb; Caris Life Sciences; Eli Lilly and Company; Foundation Medicine; Genentech;GlaxoSmithKline (GSK); Novartis; Myriad Women's Health; NeoGenomics; Pfizer; Personal Genome Diagnostics (PGDx); andThermo Fisher Scientific.
About LUNGevity Foundation
LUNGevity Foundation is the nation's leading lung cancer organization focused on improving outcomes for people with lung cancer through research, education, policy initiatives, and support and engagement for patients, survivors, and caregivers. LUNGevity seeks to make an immediate impact on quality of life and survivorship for everyone touched by the diseasewhile promoting health equity by addressing disparities throughout the care continuum. LUNGevity works tirelessly to advance research into early detection and more effective treatments, provide information and educational tools to empower patients and their caregivers, promote impactful public policy initiatives, and amplify the patient voice through research and engagement. The organization provides an active community for patients and survivorsand those who help them live better and longer lives.
Comprehensive resources include a medically vetted and patient-centric website, a toll-free HELPLine for support, the International Lung Cancer Survivorship Conference, and an easy-to-use Clinical Trial Finder, among other tools. All of these programs are to achieve our visiona world where no one dies of lung cancer. LUNGevity Foundation is proud to be a four-star Charity Navigator organization.
About Lung Cancer in the US
Please visit http://www.LUNGevity.orgto learn more.
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SOURCE LUNGevity Foundation
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Pan-Cancer Consortium Moves to Clarify and Promote Consistent Use of Common Terms for Biomarker and Germline Genetic Testing - BioSpace
Genetic Support Foundation of Olympia Announces New Resource for Hereditary Cancer Risk – ThurstonTalk
Submitted by Genetic Support Foundation
For those who have received a positive result after genetic testing for pathogenic variants that significantly increase cancer risk, a new resource is available for connecting with others who are in a similar situation.
Positive Results is a new Facebook group for support and resources around hereditary cancer risk. The group was formed by Genetic Support Foundation (GSF) to help connect the hereditary cancer community in a welcoming, digital environment. The group is administered by professionals and patients connected to GSF and aims to provide expert educational materials and to host meaningful discussions around all facets of hereditary cancer. The forum is open to those with positive results, caregivers and loved ones of those with positive results, and those in the medical community who are familiar with the unique needs of someone with hereditary cancer risk. It is not intended to replace any medical care or advice.
When patients receive a positive result for hereditary cancer risk, we often point them to external resources for support. While these resources are well-known and respected, we found that many patients want to connect with others who are going through a similar experience, explains Katie Stoll, executive director of GSF. With this new forum, we can offer people accurate information in a safe and welcoming space with support that goes beyond the counseling appointment.
Inherited pathogenic genetic variants, sometimes called mutations, play a major role in about 5 to 10 percent of all cancers. Better-known pathogenic gene variants include BRCA1 and BRCA2, which increases risk of breast and ovarian cancers, among others. But with mutations in specific genes being linked to more than 50 hereditary cancer syndromes, the hope is that all those affected will feel welcome to join the group.
Carrying the knowledge of being predisposed to cancer can be a burden, or it can be empowering, and often its both, says Nikki McCoy, who will help as an admin on the page, and who is positive for a BRCA1 gene variant. We hope that members feel empowered after visiting the group and that they feel supported and not alone. Community-building can be extremely healing and helpful.
The group is also welcoming of those who may not have had genetic testing but have a strong family history of cancer.
Women and men both have a 50 percent chance to inherit and pass down pathogenic variants. Almost all people who have a pathogenic variant will have a parent who also carries it. Many people who have a pathogenic variant and develop cancer do so at younger ages than the general population.
For more information, visit the Facebook group.
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Genetic Support Foundation of Olympia Announces New Resource for Hereditary Cancer Risk - ThurstonTalk
Direct-to-consumer Genetic Testing Market Patents Analysis 2019-2036 – Cole of Duty
The global Direct-to-consumer Genetic Testing Marketplace gives detailed Evaluation about all of the important aspects related to the marketplace. The analysis on global Direct-to-consumer Genetic Testing market, offers profound insights about the Direct-to-consumer Genetic Testing market covering all of the crucial characteristics of the market. Moreover, the report provides historical information with prospective prediction over the forecast period. Various important aspects like market trends, revenue development patterns market shares and supply and demand are included in almost all the market research report for every single business. Some of the vital aspects analyzed in the report includes market share, production, key regions, revenue rate as well as key players.
The study of different sections of the global market are also Covered in the research report. Along with that, for the prediction periods conclusion of variables such as market size and the competitive landscape of this sector is assessed in the report. On account of the rising globalization and digitization, there are new tendencies coming to the marketplace daily. The research report provides the in-depth analysis of all of these tendencies.
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Regional and Country-level AnalysisThe report offers an exhaustive geographical analysis of the global Direct-to-consumer Genetic Testing market, covering important regions, viz, North America, Europe, China, Japan, Southeast Asia, India and Central & South America. It also covers key countries (regions), viz, U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, India, Australia, Taiwan, Indonesia, Thailand, Malaysia, Philippines, Vietnam, Mexico, Brazil, Turkey, Saudi Arabia, UAE, etc.The report includes country-wise and region-wise market size for the period 2015-2026. It also includes market size and forecast by each application segment in terms of revenue for the period 2015-2026.Competition AnalysisIn the competitive analysis section of the report, leading as well as prominent players of the global Direct-to-consumer Genetic Testing market are broadly studied on the basis of key factors. The report offers comprehensive analysis and accurate statistics on revenue by the player for the period 2015-2020. It also offers detailed analysis supported by reliable statistics on price and revenue (global level) by player for the period 2015-2020.On the whole, the report proves to be an effective tool that players can use to gain a competitive edge over their competitors and ensure lasting success in the global Direct-to-consumer Genetic Testing market. All of the findings, data, and information provided in the report are validated and revalidated with the help of trustworthy sources. The analysts who have authored the report took a unique and industry-best research and analysis approach for an in-depth study of the global Direct-to-consumer Genetic Testing market.The following players are covered in this report:23andMeMyHeritageLabCorpMyriad GeneticsAncestry.comQuest DiagnosticsGene By GeneDNA Diagnostics CenterInvitaeIntelliGeneticsAmbry GeneticsLiving DNAEasyDNAPathway GenomicsCentrillion TechnologyXcodeColor GenomicsAnglia DNA ServicesAfrican AncestryCanadian DNA ServicesDNA Family CheckAlpha BiolaboratoriesTest Me DNA23 MofangGenetic HealthDNA Services of AmericaShuwen Health SciencesMapmygenomeFull GenomesDirect-to-consumer Genetic Testing Breakdown Data by TypeDiagnostic ScreeningPrenatal, Newborn Screening, and Pre-Implantation DiagnosisRelationship TestingDirect-to-consumer Genetic Testing Breakdown Data by ApplicationOnlineOffline
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The Direct-to-consumer Genetic Testing market report provides helpful insights for Every established and advanced players across the world. Additionally the Direct-to-consumer Genetic Testing marketplace report provides accurate analysis for the shifting competitive dynamics. This study report includes a whole analysis of future growth concerning the evaluation of this mentioned prediction interval. The Direct-to-consumer Genetic Testing marketplace report provides a thorough study of the technological growth outlook over time to be aware of the industry growth rates. The Direct-to-consumer Genetic Testing market report also includes innovative analysis of the massive number of unique factors that are fostering or operating as well as regulating the Direct-to-consumer Genetic Testing marketplace development.
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Direct-to-consumer Genetic Testing Market Patents Analysis 2019-2036 - Cole of Duty
Direct-to-Consumer Genetic Testing (DTC-GT) Market | Global Industry Analysis By Trends, Size, Share, Company Overview, Growth And Forecast By 2026 -…
The Global Direct-to-Consumer Genetic Testing (DTC-GT) Market analysis report published on Dataintelo.com is a detailed study of market size, share and dynamics covered in XX pages and is an illustrative sample demonstrating market trends. This is a latest report, covering the current COVID-19 impact on the market. The pandemic of Coronavirus (COVID-19) has affected every aspect of life globally. This has brought along several changes in market conditions. The rapidly changing market scenario and initial and future assessment of the impact is covered in the report. It covers the entire market with an in-depth study on revenue growth and profitability. The report also delivers on key players along with strategic standpoint pertaining to price and promotion.
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The Global Direct-to-Consumer Genetic Testing (DTC-GT) Market report entails a comprehensive database on future market estimation based on historical data analysis. It enables the clients with quantified data for current market perusal. It is a professional and a detailed report focusing on primary and secondary drivers, market share, leading segments and regional analysis. Listed out are key players, major collaborations, merger & acquisitions along with upcoming and trending innovation. Business policies are reviewed from the techno-commercial perspective demonstrating better results. The report contains granular information & analysis pertaining to the Global Direct-to-Consumer Genetic Testing (DTC-GT) Market size, share, growth, trends, segment and forecasts from 2020-2026.
With an all-round approach for data accumulation, the market scenarios comprise major players, cost and pricing operating in the specific geography/ies. Statistical surveying used are SWOT analysis, PESTLE analysis, predictive analysis, and real-time analytics. Graphs are clearly used to support the data format for clear understanding of facts and figures.
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The report segments the Global Direct-to-Consumer Genetic Testing (DTC-GT) Market as:Global Direct-to-Consumer Genetic Testing (DTC-GT) Market Size & Share, by Regions
Global Direct-to-Consumer Genetic Testing (DTC-GT) Market Size & Share, by ProductsOver-the-Counter (OTC) ChannelOnline Channel
Global Direct-to-Consumer Genetic Testing (DTC-GT) Market Size & Share, ApplicationsAncestry-based Genetic TestsHealth and Wellness-based Genetic TestsEntertainment-based Genetic Tests
Key Players24GeneticsAncestry.com LLCDante LabsEasyDNAGenebaseAtlas BiomedFamily Tree DNAMyHeritageMapmygenome
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Direct-to-Consumer Genetic Testing (DTC-GT) Market | Global Industry Analysis By Trends, Size, Share, Company Overview, Growth And Forecast By 2026 -...
Preimplantation Genetic Testing Market Anticipated to Grow at a Significant Pace by 2017 to 2022 – Cole of Duty
A recent Research published on the Global Preimplantation Genetic Testing marketplace provides a comprehensive comprehension of the general prospects of this marketplace. Whats more, the overview of the major findings of this study together with the megatrends affecting the increase of the Preimplantation Genetic Testing market is emphasized in the study. The market definition and introduction is included to assist our readers know the fundamental concepts of the analysis on the Preimplantation Genetic Testing industry.
According to the report, the Preimplantation Genetic Testing marketplace is set to increase the regional commerce analysis together with the major importers and exporters is contained in the research. Additionally, the supply-demand investigation as well as the crucial improvements in the Preimplantation Genetic Testing market are highlighted from the report.
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Important Findings of this Report
Segmentation Of this Preimplantation Genetic Testing Market
Competition Tracking
The report also profiles companies operating in the preimplantation genetic testing market, which include Agilent Technologies Inc., Abbott Laboratories, CooperSurgical Inc., Oxford Gene Technology IP, Illumina, Inc., Thermo Fisher Scientific, Inc., PerkinElmer, Inc., Genea Limited, Natera, Inc., Rubicon Genomics, Inc., and CombiMatrix Corporation.
Note: The insights mentioned here are of the respective analysts, and do not reflect the position of Fact.MR
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Preimplantation Genetic Testing Market Anticipated to Grow at a Significant Pace by 2017 to 2022 - Cole of Duty
Genesis Healthcare Co. launched ‘GeneLife Generations’, a New Ancestry Kit Designed for the Diversity and Richness of Asian Ethnicities and Ancestral…
Singapore and Taiwan to be the first markets in Asia to launch the test kit
SINGAPORE, July 7, 2020 /PRNewswire/ -- Genesis Healthcare Co., Japan's leading genetic testing and research company, today announced the launch of its Asian ancestry focused test kit, GeneLife Generations. The test kit will be officially available to customers from 20 July 2020.
From left to right: GeneLife Generations kit design and mobile application report images showcasing an ethnic mix chart and maternal migration route
Singapore and Taiwan will be the first countries in Asia to launch, followed by other markets in the coming year. GeneLife Generations has been specifically developed for the diversity and richness of the Asian ethnicities and ancestral heritage.
The GeneLife Generations Journey
Through an interactive mobile application, GeneLife Generations will bring users on a personal journey through time to discover what their DNA reveals about their ethnic mix and their lineage, providing unique experiences about possible migration routes from generations ago. This genetic composition analysis service comprehensively predicts the shared genetic composition of ancestors. Along with the genetic ancestral composition analysis, the report will identify origins and migration routes of both maternal and paternal lineages traced back to approximately 150,000 to 270,000 years ago.
Revealing Rich and Diverse Asian Ethnicities
This test kit has been specifically developed for Asian populations, unveiling the various unique ethnic origins through detailed, engaging, and rich contents. These ethnic groups include, but not limited to the following: Chinese Dai, Northern/Southern Han, Singaporean Malay, Vietnamese Kinh, Filipino, Thai, Japanese, Korean, Indonesian, Punjabi, Taiwanese, etc[1].
GeneLife Generations also covers other regions and ethnic groups from different parts of the world including Europe, Africa, and the Americas. Please note that these ethnic groups will be updated and expanded regularly as our science and research develops.
"We are truly proud to be launching GeneLife Generations amongst our suite of consumer DNA test kits," highlighted Michel Mommejat, General Manager, Genesis Healthcare Asia. "We have seen an increasing demand for Ancestry tests that truly represent the Asian population from markets that we operate in, especially Singapore. With over 16 years of R&D applied to genetics and more than 870,000 users who have taken their DNA journey with us, we are in the best position to introduce an ancestry service focused on Asia," he added.
Maternal and Paternal Ancestral Migrations
Our ancestors have travelled across the globe, looking for a place to call home in Asia. GeneLife Generations reveals migrations from maternal and paternal ancestors with an interactive display of their journeys on maps on a smartphone, supported with a dynamic chronological timeline and a range of fun and entertaining information.
The Science Behind GeneLife Generations
Genesis Healthcare is using its specially designed chip for populations in Asia and around the globe, with support from a Micro-array technology platform. For the test, DNA is simply extracted from saliva samples and subjected to genotype calling according to stringent protocols. As more users undertake the genetic test, the panel reference, algorithms, and analysis will be continuously enhanced to provide more refined information as well as reflect latest developments, technology updates and new scientific discoveries.
Story continues
Genesis Healthcare has been actively involved in genetic research and development across multiple domains and has been collaborating in joint research with the National Institute of Genetics in Japan over the years.
Availability & Price
GeneLife Generations will be launching in Singapore on 20 July 2020 at a retail price of SGD199. To celebrate this milestone, GeneLife will be running a pre-release exclusive for the first 500 customers at a discounted price of SGD129. More information can be found on http://www.genelife.asia/product_generations.
About Genesis Healthcare Co. Ltd
Genesis Healthcare Co., Ltd. is a leading biotech company, pioneering genetic research since 2004 and promoting preventive healthcare and wellness through genetic testing. Leveraging more than 16years of genetic research and development, Genesis Healthcare empowers medical institutions and end consumers alike to evolve towards personalized wellness and medicine. Over the years, more than 857,000+ users have trusted GeneLife and Genesis Healthcare to undertake genetic testing. This has allowed the company to validate and improve its science and algorithms over time. Originated in Japan, Genesis Healthcare offers medical, corporate, and consumer services through a range of innovative services across the Asia Pacific region. GeneLife is the direct-to-consumer brand of Genesis Healthcare.
Photo - https://photos.prnasia.com/prnh/20200707/2850185-1
SOURCE Genesis Healthcare Co. Ltd
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Genesis Healthcare Co. launched 'GeneLife Generations', a New Ancestry Kit Designed for the Diversity and Richness of Asian Ethnicities and Ancestral...