Movies for the human genome

Posted: April 4, 2010 at 1:49 am

Story Summary: This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely available, as the result of a study in which they have identified the genes involved in mitosis – the most common form of cell division – in humans. Published today in Nature, their work begins to unravel the molecular workings of one of the most fundamental processes of life: how one cell becomes two. The end result is that we now have a very rich resource for the scientific community, as were making all the movies and all the analysis data freely available online, Ellenberg emphasises: Scientists can go to the website, type in the name of their favourite gene, and watch what happens when it is silenced; they can find out what other genes have similar effects – all in a few mouse clicks, instead of months or years of work in the lab!But mitosis is not solved yet, the scientists say. They have yet to uncover exactly how these genes act at the molecular level – a task which will be tackled by a follow-up project called Mitosys. A year after we developed these new siRNA microarrays, says Rainer Pepperkok, who led the methods development at EMBL, theyre already in use by over 10 research groups from across Europe….Read the Full Story

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